---
title: 'Principal Scientist (PD/MSAT) at Mytos'
canonical: 'https://feeny.ai/job/principal-scientist-pd-msat-mytos-london-k1sg669m78rx'
type: 'job'
last_seen: '2026-09-11'
---

# Principal Scientist (PD/MSAT) at Mytos

- **Company:** Mytos
- **Location:** London, United Kingdom
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-06-18
- **Last confirmed live:** 2026-09-11
- **Apply:** https://jobs.lever.co/mytos/dba7160d-a0f2-4891-9294-1fbc60689dbd

## Job description

About Us: You rarely get the chance to change an entire industry. But that's the position we find ourselves in. Join us, and you’ll help scale cures to patients that need them sooner. We’ve developed fully-automated cell manufacturing sites powered by custom robotics - to scale therapies to millions of patients. Last year, patients were cured of diseases like Parkinson’s Disease and vision loss using stem-cell derived cells - but today these Regenerative Medicines are produced by hand, meaning they’re too expensive and hard to scale. With our automated CDMO, these therapies can now be scaled globally at low cost. We've announced partnerships across multiple therapies so far ranging from Parkinson’s, to hearing loss, to bone repair - and raised $24m to expand into the market faster, and accelerate our development! Within the next 12-18 months, neurons grown on our machines will be going into Parkinson’s patient brains. We’ve assembled a world-class team to take on this challenge, with ex-Dyson engineers and Nature-published scientists working hand-in-hand. You can learn more about your potential Mytos teammates here: Team Mytos is backed by Y Combinator, the most successful startup program in the world which produced companies such as AirBnb, Dropbox, and Ginkgo Bioworks.

The Role: We are looking for a high-growth principal PD/MSAT Scientist to join our Biology team and push the limits of automation in cell therapy manufacture. This is a unique opportunity to learn how to execute projects at the interface of engineering and biology with a direct impact to patients.

Core Responsibilities:

- Provide technical leadership in the set up and operation of Mytos Bio’s CDMO site in Stevenage. Travel between London and Stevenage sites will be required where necessary.
- Lead process development and analytical method development projects in line with customer requirements.
- Plan and execute technology transfer activities, ensuring compliance with relevant regulatory standards.
- Drive continuous process improvement through the implementation of best practices, methods, and high quality standards.
- Support resource planning and timeline development for new projects.
- Help build out the teams technical capabilities by supporting hiring efforts and mentoring colleagues.
- Support business development activities through direct client engagement and involvement in the drafting of sales proposals.

## Skills & Experience

Required:

- PhD in Cell Biology (or related discipline) with 3+ years of industry experience, or 5+ years of relevant industry experience.
- Subject matter expertise in cell therapy development and manufacture across the PD → MSAT → cGMP pipeline.
- Subject matter expertise in optimising human stem cell culture (ESC/iPSC), differentiation, and characterisation under cGMP conditions.
- Strong understanding of regulatory requirements for cell therapy manufacture (MHRA, EMA, or FDA).
- Experience authoring quality documentation for cGMP manufacturing and QC.
- Demonstrated ability to lead, manage and deliver complex projects with multiple dependencies.
- Strong experimental design and analytical skills.
- Excellent communication and teamwork skills across multiple levels (customers, team members and inter departmental).
- Experience in a line manager capacity.

Desired:

- Prior experience developing cell therapy products that have been taken to Phase I clinical trials or beyond.
- Prior experience working in or with CDMOs.

Salary and Benefits

- Competitive salary with stock options
- Lunch covered daily
- Collaborative team environment with very high potential to learn new skills
- 24 days holiday (excluding bank holidays)
- Pension
- Awesome colleagues and an office in the Imperial College Innovation hub in White City, where you’ll be based.

We’re building a team that enjoys moving fast, strives for continuous improvement through learning from mistakes and is passionate about work that contributes to solving real world problems. Join us if you want a fast-paced environment, where you’re empowered to make decisions and do the best work of your career.

## About Mytos

## Company Overview
- **One-liner**: Mytos is building the world’s first fully automated cell manufacturing platform to scale regenerative medicines from clinical trials to millions of patients at low cost.
- **Entity Type**: Private (Series A, $24M+ total funding)
- **Headquarters**: London, United Kingdom
- **Founded**: 2016
- **Founders**: Ali Afshar (CEO) and Ignacio Willats

## Core Business
- **Primary industry**: Biotechnology / Regenerative Medicine / Automated Cell Therapy Manufacturing
- **Target customers**: Clinical-stage cell therapy companies (B2B, Enterprise CDMO), large pharma R&D groups
- **Mission**: To scale regenerative medicines to millions of patients by automating the production of stem cell-derived therapies

## Products & Services
- **iDEM™ Platform**: Proprietary automated cell culture system that uses standard 2D T-flasks to seamlessly port manual protocols into closed, scalable automation without compromising biology. Reduces labour per batch by up to 10x and cleanroom footprint per batch by another 10x.
- **Mytos CDMO**: A fully automated contract development and manufacturing organization (CDMO) powered by iDEM technology. Site 1 is housed within the Cell and Gene Therapy Catapult’s 80,000 sqft facility in Stevenage, UK. Offers end-to-end manufacturing services including Process & Analytical Development, Regulatory Support, and batch production with up to 50% lower batch costs compared to manual CDMOs.

## Market Standing
- **Valuation**: Not publicly disclosed
- **Key Metric**: Total funding of over $24M (Series A led by Buckley Ventures in November 2023; prior rounds include Y Combinator, IQ Capital, and TBD Angels)
- **Notable Investors/Partners**: Y Combinator, Buckley Ventures, IQ Capital; founders/execs from Wayve, Dropbox, Segment, Mercury, Sana, BMS, Revolut; partnerships with Pluristyx, NOVADIP Biosciences, StemSight, and Rinri Therapeutics
- **Growth Signals**: Headcount of ~27 employees (+11.6% YoY); announced three cell therapy manufacturing deals in September 2025; launched automated CDMO in October 2025; first in-patient dosing targeted for 2027; 5 active job postings; strong LinkedIn follower growth (+39.4% yearly)

## Competitive Advantages
- **Biology-preserving automation**: Uses the same 2D T-flask format as manual culture, meaning no need to re-engineer existing protocols — a major barrier to adoption for competing solutions.
- **Fleet architecture**: Unlike large robotic-arm solutions, the iDEM fleet has no single point of failure, increasing reliability for clinical/commercial production.
- **Cost leadership**: Claims up to 50% lower batch costs vs. manual CDMOs and 10x labour reduction, making therapies economically viable at scale.
- **End-to-end CDMO model**: Integrates process development, regulatory support, and manufacturing under one roof, reducing tech transfer delays.

## Strategic Focus
- **Scale the CDMO**: Expand global manufacturing sites beyond the UK (plans in place for a series of global sites).
- **Clinical validation**: Move from R&D partnerships to clinical-stage manufacturing, with cells produced on iDEM entering patients by 2027.
- **Partnership pipeline**: Continue signing deals across multiple therapeutic areas (Parkinson’s, blindness, bone repair, hearing loss) to diversify revenue and de-risk technology.
- **Hiring for growth**: Actively recruiting across engineering, quality, and scientific leadership to support CDMO ramp-up.

## Why Work Here
- **Mission-driven impact**: Directly work on curing Parkinson’s, blindness, and spinal cord injuries at scale — a rare combination of deep tech and patient impact.
- **Culture & team**: Rated 4.5/5 on employer review platforms (Culture: 4.4, Career: 4.6). Team includes engineers from Dyson, Autodesk, and Matic Robots alongside Nature-published scientists.
- **Work location**: On-site in London (HQ at 80 Wood Lane) with additional offices in Newark, California and Billingstad, Norway.
- **Growth opportunity**: Early-stage company (27 people) with clear trajectory to clinical manufacturing — offers outsized ownership and impact for early hires.
- **Perks & environment**: Fast-paced startup environment; cross-disciplinary collaboration between hardware, software, and biology teams; close ties to Y Combinator and top-tier biotech investors.

## Sources
1. [mytos.bio](https://www.mytos.bio/)
2. [mytos.bio/about](https://www.mytos.bio/about)
3. [mytos.bio/team](https://www.mytos.bio/team)
4. [jobs.lever.co/mytos](https://jobs.lever.co/mytos)
5. [linkedin.com/company/mytosbio](https://linkedin.com/company/mytosbio)

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