--- title: 'Principal Software Quality Engineer at Pulse Biosciences' canonical: 'https://feeny.ai/job/principal-software-quality-engineer-pulse-biosciences-hayward-ac4c4axzx95d' type: 'job' last_seen: '2026-10-25' --- # Principal Software Quality Engineer at Pulse Biosciences - **Company:** Pulse Biosciences - **Location:** Hayward, CA - **Work type:** onsite - **Posted:** 2026-10-19 - **Last confirmed live:** 2026-10-25 - **Apply:** https://job-boards.greenhouse.io/pulsebiosciences/jobs/5454597008 ## Job description Pulse Biosciences (Nasdaq: PLSE): Join the Future of Bioelectric Medicine Pulse Biosciences is a novel bioelectric medicine company committed to health innovation that has the potential to improve the quality of life for patients.  The Company’s proprietary CellFX® nsPFA™ (nanosecond Pulsed Field Ablation) technology delivers nanosecond pulses of electrical energy to non-thermally ablate cells while sparing adjacent noncellular tissue. The Company is actively pursuing the development of its CellFX nsPFA technology for use in the surgical treatment of atrial fibrillation and percutaneously in a select few other markets where it could have a profound positive impact on healthcare for both patients and providers. Visit [pulsebiosciences.com](https://cts.businesswire.com/ct/CT?id=smartlink&url=http%3A%2F%2Fpulsebiosciences.com%2F&esheet=53299490&newsitemid=20230202005390&lan=en-US&anchor=pulsebiosciences.com&index=2&md5=be5397cf42a2c83df28cd007fa26f3d9) to learn more. Why Join Us? At Pulse Biosciences, we are driven by purpose and innovation. - Our Mission: To build a viable Company that designs, produces, and commercializes nano-pulse technology to improve and extend the lives of patients. To solve the needs of patients, physicians, and healthcare providers with high quality and high reliability products and services, developed in accordance with rigorous scientific, engineering, and clinical standards.  We exist to make a positive difference in the lives of patients, physicians, healthcare providers, shareholders and our Pulse Biosciences team members. - Our Culture: A community of creative, forward-thinking individuals tackling challenges with ingenuity and collaboration. - Our Commitment: Hiring the best and brightest minds to advance our world-class organization. What You Will Experience: - Culture and Purpose - Purposeful and rewarding work collaborating with bright and curious minds brings us together! - Innovative Environment - An environment that fosters innovation to take products from concept to human use quickly! - Growth Opportunities - Learning culture focusing on professional and personal growth and development that you can only get in a startup-like environment! - Comprehensive Benefits - A variety of health insurance plans and supplemental insurance options, and 401k retirement savings plan. - Ownership and Rewards - Stock options awards and Employee Stock Purchase Plan (ESPP) to share in our success. - Work-Life Balance - Enjoy paid time off, paid holidays, flexible work schedule and wellness program, including onsite gym and mindfulness classes. - Diversity & Inclusion - A commitment to providing a respectful work environment to our diverse workforce. ## About the Role The Principal Software Quality Engineer will be responsible for quality assurance activities related to software/system development, verification, validation, and overall system functionality and reliability of the CellFX system and accessories in support of the Company’s research and development, manufacturing, regulatory, clinical investigations, and commercial efforts.  In addition, this position will support the development and implementation of quality systems and regulatory filing activities. To Make an Impact, You Will: - Provide expertise and guidance to product development and manufacturing teams in the areas of SW quality assurance, design controls and compliance. - Develop, establish and maintain SW quality engineering methodologies, systems and practices that meet Pulse Biosciences’ customer and regulatory requirements. - Proactively investigate, identify and implement best-in-class SW quality engineering practices. - Identify and implement effective process control systems to support the development, qualification and on-going manufacturing of products to meet or exceed internal and external requirements. - Develop and validate SW methods, monitor medical device SW standards, facilitate and perform SW code review. - Assist with preparation of regulatory submissions, regulatory assessments related to software changes and cybersecurity. - Development of SW standard operating procedures, SW test methodologies, and software verification & validation protocols and reports. - Design and implement methods and procedures for SW release, SW field upgrade, and final quality assurance. - Work closely with the Software Development Team to plan, schedule, and improve development test processes. - Work well in a collaborative team environment with other engineers, developers and end users with minimal supervision and ensure understanding and validation of business requirements. - Perform validation and verification testing of medical devices and equipment in an FDA regulated environment. - Support internal quality audits, management review activities, Notified Body audits (ISO), and FDA QSIT audits. - Assist with development of product labeling, translation, and investigator brochures for commercial and clinical studies. - Supervise employees as assigned. - Carry out responsibilities in accordance with the organization’s policies and applicable laws. - Support the Pulse Biosciences Quality Policy and Quality System. To Excel, You Will Bring: - Bachelor’s degree in Computer Science, Software Engineering, Computer Engineering or related field. - 10+ years hands-on working experience in the field of SW quality assurance, SW testing, and/or SW development with at least 5+ years working with complex energy-based medical device system and Class III devices with SW. Cardiovascular devices are preferred. - Familiarity with the use of quality disciplines, tools, and methodologies - Working experience with various FDA software validation and Cybersecurity guidance’s and IEC 62304 Software Lifecycle process standard requirements - Must have working knowledge and experience in the following areas: Design Control, Design & Process Validation, Risk Management, Cybersecurity, Quality system compliance, Complaint handling, MDR/Vigilance Reporting, and CAPA program. - ANSI/AAMI/IEC 62304:2006 Medical device software –Software life cycle processes - Medical Electrical Safety and EMC standards (IEC 60601-1, IEC 60601-1-2) and Risk Assessment (ISO 14971: 2019) including Cybersecurity practices and implementation. - The ideal candidate will have background in software test development, test methodologies and test automation for native applications built QNX or Similar OS. - Good communication skills, including experience writing technical documentation, test protocol, test reports, etc. - Must have excellent oral and written communication and project management skills - Proven ability to independently manage critical projects as part of an interdisciplinary team and navigate challenges to deadlines. - Hands-on experience preparing, managing and submitting major regulatory submissions. - Ability to work conscientiously and with minimal direction, using good judgment, taking initiative to accomplish short and long-range projects, and recommend actions with minimal direction. - Ability to work as a team member, multi-task and be very flexible to adapt to the ever-changing work priorities and requirements of a dynamic, fast-growing company. - Proficient knowledge and skill in Microsoft Office Suite applications. - Ability to travel up to 10% of the time. Overnight and/or international travel may be required. - Ability to lift 10-15 pounds. Pay Range: Compensation is determined based on a wide range of factors including location, job-related skills, experience, education, and training. It is not typical for an individual to be hired at or near the top of the range for their role. This pay range is specific to Northern California location. Base salary range: $165k-$200k. This position is located onsite in Hayward, CA and candidates must reside in the San Francisco Bay Area. No relocation offered. Ready to Shape the Future of Healthcare? Apply today to join Pulse Biosciences and help us redefine the boundaries of medicine with bioelectric innovation.  To learn more about us, visit our website at [www.pulsebiosciences.com](http://www.pulsebiosciences.com). We provide equal employment opportunities (EEO) to all persons regardless of race, age, color, gender, sexual orientation, national origin, physical or mental disability, religion, or any other characteristic protected by federal, state or local law. We will make reasonable accommodations for qualified individuals with disabilities. PRINCIPALS ONLY; UNSOLICITED CANDIDATE SUBMISSIONS FROM RECRUITERS OR THIRD-PARTY AGENCIES WILL BE CONSIDERED FREE REFERRALS. ## About Pulse Biosciences ## Company Overview - **One-liner**: Pulse Biosciences is a bioelectric medicine company developing and commercializing its proprietary Nanosecond Pulsed Field Ablation (nsPFA) technology for nonthermal ablation of soft tissue, with initial applications in dermatology and expanding into cardiac electrophysiology and thyroid nodule treatment. - **Entity Type**: Public (ticker symbol not specified in provided search results; company maintains an investor relations page and files SEC reports). - **Headquarters**: Hayward, CA (derived from job listings showing Hayward addresses). - **Founded**: Not publicly available in provided sources. - **Founders**: Not publicly available in provided sources. ## Core Business - **Primary industries**: Medical devices, bioelectric medicine, electrophysiology, dermatology, and interventional cardiology. - **Target customers**: B2B – hospitals, clinics, and physicians (electrophysiologists, cardiologists, dermatologists, and surgeons). - **Mission**: “To build a viable Company that designs, produces, and commercializes nano-pulse technology to improve and extend the lives of patients.” (source: [pulsebiosciences.com/about-us](https://www.pulsebiosciences.com/about-us/)) ## Products & Services - **CellFX® nsPFA System** – The first commercial product harnessing nsPFA energy for dermatologic conditions (e.g., clearing cells nonthermally). Multi-application platform with a utilization-based revenue model. Used to treat over 6,000 patients outside of cardiology. - **nPulse™ Vybrance™ Percutaneous Electrode** – An investigational device for nonthermal ablation of benign thyroid nodules. First-in-human clinical study results presented at the 2024 NASIT Annual Meeting; 30 patients treated. Not yet cleared by FDA. - **CellFX® nsPFA™ 360 Cardiac Catheter** – Catheter-based system for atrial fibrillation (AF) ablation. First-in-human feasibility study of 150 patients showed rapid procedure times and minimal adverse effects, presented at the 31st Annual AF Symposium (Feb 2026). - **CellFX® nsPFA™ Cardiac Clamp** – A surgical cardiac ablation device designed to produce continuous linear transmural ablations. Submitted for 510(k) clearance to the FDA. - **nsPFA™ Generator Platform** – A versatile generator that connects to multiple applicator types (superficial, surgical, catheter-based), supporting the company’s pipeline. ## Market Standing - **Valuation/Market Cap**: Not disclosed in provided search results. - **Key Metric**: Over 6,000 patients treated safely and effectively outside of cardiology (source: [pulsebiosciences.com/technology](https://www.pulsebiosciences.com/technology/)). - **Notable Investors/Partners**: Not explicitly named in provided materials; the company has a deep IP portfolio and partnerships with clinical leaders such as Dr. Vivek Reddy (Mount Sinai Fuster Heart Hospital, NY). Board appointments include Maria Sainz (President & CEO of Hyperfine, Inc.) and Dr. David Kenigsberg (Chief Medical Officer of Electrophysiology). - **Growth Signals**: - Two 510(k) submissions to the FDA (Cardiac Clamp and Percutaneous Electrode) filed in 2025/2026. - First-in-human data for the Cardiac Catheter (150 patients) presented at major symposium; positive 60-day follow-up results from an early cohort. - Expansion from dermatology into cardiac and thyroid indications. - Over 130 issued patents globally (source: [pulsebiosciences.com/about-us](https://www.pulsebiosciences.com/about-us/)). ## Competitive Advantages - **Proprietary nsPFA technology** – Nonthermal mechanism spares noncellular tissue, offering potential safety benefits over thermal ablation. - **Broad IP moat** – Over 130 issued patents globally provide strong defensibility. - **Multi-application platform** – The nsPFA generator can be paired with different applicators, enabling entry into multiple large markets (dermatology, cardiac surgery, electrophysiology, thyroid). - **Clinical validation** – Demonstrated safety and efficacy in >6,000 patients across non-cardiac uses, plus promising cardiac first-in-human data. ## Strategic Focus - Securing FDA clearances for the cardiac clamp and percutaneous electrode (510(k) submissions underway). - Advancing the cardiac catheter program toward pivotal studies and commercialization. - Expanding the pipeline of nsPFA applications into additional therapy areas (e.g., other soft tissue ablations). - Growing the IP portfolio and extending the platform’s reach into surgical and interventional settings. ## Why Work Here - **Culture**: The company describes itself as “best suited for individuals who are creative, forward‑thinking and who approach challenges with an innovative attitude” (source: [job-boards.greenhouse.io/pulsebiosciences](http://job-boards.greenhouse.io/pulsebiosciences)). - **Work arrangements**: Roles are offered in Hayward, CA; some positions are hybrid (e.g., Patent Agent, Sr. Manager Technical Accounting) and others are onsite (e.g., Sr. Quality Engineer, Manager Electrical Engineering). - **Impact**: Employees work on a novel bioelectric medicine platform with the potential to change standard of care in cardiac and soft tissue ablation – directly improving patient outcomes. - **Team**: “Top experts in pulsed electric field technologies with a broad range of engineering expertise across multiple medical device domains.” (source: [pulsebiosciences.com/about-us](https://www.pulsebiosciences.com/about-us/)) ## Sources 1. [pulsebiosciences.com](https://www.pulsebiosciences.com/) – Main corporate site and latest news 2. [pulsebiosciences.com/about-us](https://www.pulsebiosciences.com/about-us/) – About Us, mission, and IP 3. [pulsebiosciences.com/technology](https://www.pulsebiosciences.com/technology/) – Technology description and patient data 4. [investors.pulsebiosciences.com](https://investors.pulsebiosciences.com/) – Investor relations (public company presence) 5. [job-boards.greenhouse.io/pulsebiosciences](http://job-boards.greenhouse.io/pulsebiosciences) – Careers page and job listings ## Other roles at Pulse Biosciences - [GENERAL JOB APPLICATION](https://feeny.ai/job/general-job-application-pulse-biosciences-hayward-k6mxn676e6bj) — Hayward, CA - [Principal Quality Engineer](https://feeny.ai/job/principal-quality-engineer-pulse-biosciences-hayward-aymxfercgy5f) — Hayward, CA - [Principal Global Regulatory Affairs Specialist](https://feeny.ai/job/principal-global-regulatory-affairs-specialist-pulse-biosciences-hayward-db6aq3v25dd3) — Hayward, CA - [Director, Clinical Affairs - Minimally Invasive Surgery Market](https://feeny.ai/job/director-clinical-affairs-minimally-invasive-surgery-market-pulse-biosciences-7erdqgq5854e) — Hayward, CA - [Sr. Systems Administrator](https://feeny.ai/job/sr-systems-administrator-pulse-biosciences-hayward-7mxeh4vswz75) — Hayward, CA - [Sr. Software Test Automation Engineer](https://feeny.ai/job/sr-software-test-automation-engineer-pulse-biosciences-hayward-1nt1acgf66th) — Hayward, CA - [Corporate Paralegal/Sr. Corporate Paralegal](https://feeny.ai/job/corporate-paralegal-sr-corporate-paralegal-pulse-biosciences-hayward-vd1rhrj9v022) — Hayward, CA - [Sr. Process Development Engineer, Catheter Engineering](https://feeny.ai/job/sr-process-development-engineer-catheter-engineering-pulse-biosciences-hayward-b3qv7n2cdz0n) — Hayward, CA - [Sr. Clinical Research Associate (Cardiac Catheter Products)](https://feeny.ai/job/sr-clinical-research-associate-cardiac-catheter-products-pulse-biosciences-fn14sg07jk2a) — United States - [Sr. Clinical Research Associate (Soft Tissue Ablation)](https://feeny.ai/job/sr-clinical-research-associate-soft-tissue-ablation-pulse-biosciences-united-8hqypfxjpffh) — United States