---
title: 'Procurement Manager at Xaira Therapeutics'
canonical: 'https://feeny.ai/job/procurement-manager-xaira-therapeutics-south-san-francisco-368fe4j3aymx'
type: 'job'
last_seen: '2026-10-19'
---

# Procurement Manager at Xaira Therapeutics

- **Company:** Xaira Therapeutics
- **Location:** South San Francisco, CA
- **Posted:** 2026-09-22
- **Last confirmed live:** 2026-10-19
- **Apply:** https://job-boards.greenhouse.io/xairatherapeutics/jobs/5244683007

## Job description

## About Xaira Therapeutics

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

## The Role

Xaira is seeking a Procurement Manager at the leading edge of the function — a builder who treats procurement as a commercial engine and a proving ground for AI-enabled operations. You're obsessed with stakeholders: scientists, engineers, and business partners are your customers, and their success is your scoreboard. You'll inherit a strong foundation but you have an obsession to drive the function beyond the empirical high-bar. This position is based in South San Francisco, CA.

## What You'll Do

Operations Leadership

- Own end-to-end procurement operations: P2P process, sourcing, and technology enablement across all goods and services
- Drive adoption of our contract-first CLM framework while reducing cycle times
- Run procurement as a service business, with stakeholder experience as a core focus
- Support Accounting: PO hygiene, invoice-match resolution, accruals, vendor master data and close activities

AI Enablement

- Pilot and scale AI across the lifecycle: contract analysis, spend classification, supplier intelligence, negotiation prep, workflow automation
- Make Xaira's procurement a showcase for AI-augmented operations — measured in cycle time, coverage, and cost
- Translate the emerging procure-tech landscape into practical and adopted tooling

Supplier Engagement & Negotiations

- Lead sourcing events and negotiations across core life-sciences suppliers
- Structure agreements that protect Xaira's flexibility: competitive tension, cancellation frameworks and leading engagement terms
- Build supplier relationships that scale: performance management, risk monitoring and strategic partnerships

Procure-Tech, Data & Analytics

- Drive build-vs-buy decisions across the stack (P2P, CLM, sourcing, cost savings/avoidance) with an emphasis toward lean, high-leverage solutions
- Build spend analytics that turn data into decisions: category insights, supplier concentration, budget-to-actual
- Own data integrity across procurement and P2P systems

## What You Bring

- 5+ years in procurement, strategic sourcing, or supply chain; biotech, pharma, or high-growth tech preferred
- Proven negotiation results on complex service agreements (CRO, services, and technology)
- Hands-on with modern procurement tools (Ironclad, Coupa, NetSuite, Ramp) and curiosity about what replaces them
- Practical AI fluency applied to real workflows — you can point to processes you've automated
- Strong analytics: spend analysis, dashboarding, supplier ecosystems, advanced metrics and analytics giving Xaira leverage as a competitive advantage among Xaira’s peer group
- Stakeholder obsession - Building trust through accountability and delivery making Procurement an invaluable business partnership
- Concise, executive-ready communication
- Entrepreneurial: you find the gap, propose the fix, and ship it

## Why This Role Matters

Every dollar and every week Procurement saves is capacity redirected toward discovering new medicines. If you want to build the most advanced Procurement function in biotech, this is the seat.

## Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity.  The base pay range for this position is expected to be $124,000 - $155,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.

## About Xaira Therapeutics

## Company Overview
- **One-liner**: Xaira Therapeutics is an integrated biotechnology company applying artificial intelligence across the entire drug discovery and development process to design next-generation medicines.
- **Entity Type**: Private (Series A)
- **Headquarters**: South San Francisco, California, United States (with offices in Seattle, Washington, and London, UK)
- **Founded**: 2023
- **Founders**: Co-founded and incubated by ARCH Venture Partners and Foresite Labs, with foundational scientific contributions from Nobel Laureate Dr. David Baker (Institute for Protein Design, University of Washington).

## Core Business
- **Primary industry/industries**: Biotechnology, Drug Discovery & Development, Artificial Intelligence
- **Target customers**: B2B (pharmaceutical partners, biotech collaborators) and ultimately patients via its own therapeutic pipeline.
- **Mission or purpose statement**: "Pioneering the transformative artificial intelligence that will help discover and develop the next generation of life-changing medicines." [xaira.com](https://www.xaira.com/)

## Products & Services
- **AI-Powered Drug Discovery Platform**: An end-to-end platform integrating advanced AI research, expansive data generation (functional genomics, proteomics, multi-omics), and robust therapeutic product development to shift drug discovery from an empirical science to a precise engineering discipline. [xaira.com](https://www.xaira.com/our-approach)
- **Computational Protein Design**: Built on foundational work by Nobel Laureate Dr. David Baker, leveraging AI to design entirely new proteins from scratch for previously undruggable targets. [xaira.com](https://www.xaira.com/our-approach)
- **X-Cell (Virtual Cell Model)**: An AI model trained on billions of genomic data points to simulate and understand cellular biology. [xaira.com](https://www.xaira.com/)
- **Therapeutic Pipeline**: A pipeline of differentiated therapeutics across multiple modalities (small molecules, biologics, protein therapeutics) developed through an integrated AI-driven process.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed. The company launched in 2023 with a $1 billion Series A financing, one of the largest in biotech history.
- **Key Metric**: Total Funding of $1 billion (Series A, 2023).
- **Notable Investors/Partners**: ARCH Venture Partners (co-founder and lead investor), Foresite Labs (co-founder and incubator), F-Prime Capital, and other top-tier investors. Board includes leaders from ARCH, Foresite, NEA, and Johnson & Johnson. Scientific advisors include Nobel Laureates Carolyn R. Bertozzi and David Baker, and other luminaries. [xaira.com](https://www.xaira.com/our-team)
- **Growth Signals**: Launched in 2023 with a record $1B Series A; rapidly building a world-class team across three global hubs (South San Francisco, Seattle, London); actively hiring across AI, computational biology, protein design, and drug development roles; announced X-Cell, a virtual cell model trained on billions of genomic data points. [xaira.com](https://www.xaira.com/)

## Competitive Advantages
- **Unprecedented Capital & Talent**: Launched with a $1B Series A, enabling aggressive hiring of top-tier AI and biology talent and long-term investment in infrastructure.
- **End-to-End AI Integration**: Uniquely positioned to apply AI across the entire drug discovery and development lifecycle, from target identification to clinical development, creating a powerful data flywheel.
- **World-Class Scientific Foundation**: Built on foundational AI protein design work from Nobel Laureate David Baker's lab, with a board and advisory board including multiple Nobel Laureates, former FDA commissioners, and industry leaders from Genentech, Johnson & Johnson, and top venture firms. [xaira.com](https://www.xaira.com/our-team)
- **Massive Data Generation**: Investing heavily in functional genomics and proteomics to generate proprietary, multi-dimensional datasets that fuel AI model development, creating a defensible data moat.

## Strategic Focus
- **End-to-End AI Integration**: Building predictive and agentic AI models across the complete drug discovery and development spectrum to increase probability of success, reduce timelines, and lower costs. [xaira.com](https://www.xaira.com/our-approach)
- **Data as a Core Asset**: Generating and integrating massive, multi-dimensional biological datasets (from molecular to human scales) to train and improve AI models continuously.
- **Pipeline Development**: Advancing a pipeline of differentiated therapeutics across multiple modalities (small molecules, biologics, protein therapeutics).
- **Talent Acquisition**: Aggressively hiring across AI research, engineering, computational biology, protein design, and drug development to build a world-class, interdisciplinary team.

## Why Work Here
- **Mission-Driven**: Opportunity to work at the forefront of AI and biology to fundamentally transform how medicines are discovered and developed, with the potential to impact millions of patients.
- **World-Class Team & Mentorship**: Work alongside and learn from Nobel Laureates, top AI researchers, and experienced drug developers from leading pharma and biotech companies. [xaira.com](https://www.xaira.com/our-team)
- **Interdisciplinary Culture**: A unique blend of AI/ML engineers, protein designers, computational biologists, and drug hunters all working together in a highly collaborative environment.
- **Global Hubs & Flexibility**: Offices in South San Francisco, Seattle, and London, offering multiple locations for talent.
- **Generous Resources**: Backed by a $1B Series A, providing the resources to pursue ambitious, long-term research without short-term funding pressure.
- **Job Scam Awareness**: The company has issued a warning about fraudulent job offers; all legitimate recruitment is conducted through official channels (Greenhouse) and never via Google Chat or requests for payment. [xaira.com](https://www.xaira.com/work-with-us)

## Sources
1. [xaira.com](https://www.xaira.com/)
2. [xaira.com](https://www.xaira.com/our-approach)
3. [xaira.com](https://www.xaira.com/our-team)
4. [xaira.com](https://www.xaira.com/work-with-us)
5. [greenhouse.io](https://job-boards.greenhouse.io/xairatherapeutics)

## Other roles at Xaira Therapeutics

- [Principal Scientist, Target Discovery & Portfolio Strategy](https://feeny.ai/job/principal-scientist-target-discovery-portfolio-strategy-xaira-therapeutics-e1120npv099c) — South San Francisco, CA
- [Senior Scientist, Antibody Characterization](https://feeny.ai/job/senior-scientist-antibody-characterization-xaira-therapeutics-south-san-28jxkpddcby2) — South San Francisco, CA
- [Senior Project Manager, Biologics R&D - Early Pipeline Programs](https://feeny.ai/job/senior-project-manager-biologics-r-d-early-pipeline-programs-xaira-therapeutics-36myc85pkttj) — South San Francisco, CA
- [Vice President, Clinical Development, Oncology](https://feeny.ai/job/vice-president-clinical-development-oncology-xaira-therapeutics-south-san-nwq8tfzcf3d0) — South San Francisco, CA
- [Senior Director, Clinical Operations](https://feeny.ai/job/senior-director-clinical-operations-xaira-therapeutics-south-san-francisco-nrx5ytj3me96) — South San Francisco, CA
- [Principal Scientist, Protein Engineering](https://feeny.ai/job/principal-scientist-protein-engineering-xaira-therapeutics-south-san-francisco-2dwzf5jmc3sv) — South San Francisco, CA
- [Research Associate / Senior Research Associate, Genomic Core](https://feeny.ai/job/research-associate-senior-research-associate-genomic-core-xaira-therapeutics-ds5ts7k1r4px) — South San Francisco, CA
- [Scientist II, High Throughput Biology](https://feeny.ai/job/scientist-ii-high-throughput-biology-xaira-therapeutics-south-san-francisco-dp58zy18q1wd) — South San Francisco, CA
- [Principal Scientist, Biology](https://feeny.ai/job/principal-scientist-biology-xaira-therapeutics-south-san-francisco-2azp7k7sb0b2) — South San Francisco, CA
- [Lab Software Engineer](https://feeny.ai/job/lab-software-engineer-xaira-therapeutics-south-san-francisco-mt9p82bbxdfp) — South San Francisco, CA