---
title: 'Product Manager, Science at Helix'
canonical: 'https://feeny.ai/job/product-manager-science-helix-united-states-rmmtfptp60qt'
type: 'job'
last_seen: '2026-10-20'
---

# Product Manager, Science at Helix

- **Company:** Helix
- **Location:** United States
- **Compensation:** $144k–$189k
- **Employment:** full-time
- **Work type:** remote
- **Posted:** 2026-10-16
- **Last confirmed live:** 2026-10-20
- **Apply:** https://jobs.gem.com/helix/am9icG9zdDqZ_8xgzulNH3b8Bh5R3Hey

## Job description

## Who We Are & What We Do

At Helix, our mission is simple: to help everyone improve their lives through their DNA.

Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics.

What is special about this role?

At Helix, we’re focused on improving patient lives, and this role sits at the center of that work. The Product team builds tools that support clinical genomics workflows at Helix. In this role, you’ll shape products for case management, data workflows, clinical review and sign-out, and data delivery. Your work will help lab directors, scientists and engineering teams deliver genomic insights efficiently while protecting clinical quality.

As a Product Manager, you will:

- Define the Vision: Set and own product priorities for case management, data workflows, clinical review and sign-out, and data delivery, translating input from clinical users and business partners into a roadmap the team can execute against.
- Accelerate Innovation: Use AI to build and iterate quickly, from user research to prototypes to specs, giving it clear context so outputs need minimal rework, while reserving your own judgment for strategy and stakeholder alignment.
- Simplify Complexity: Distill nuanced clinical needs into elegant, scalable product requirements while maintaining a relentless focus on priority.
- Balance & Scale: Navigate high-stakes tradeoffs to deliver efficiency and scalability without ever compromising on clinical quality.
- Unify Teams: Act as the bridge between lab directors, scientists, and global engineering teams to ensure seamless product releases.
- Guardian of Trust: Oversee the health of your product area, including data privacy, security, and governance within our AI-driven solutions.

About you:

- Educational Foundation: B.S. or M.S. in Biology, Engineering, or a related technical field.
- Domain Expertise: Deep experience or knowledge of clinical genomics and variant interpretation; you understand the science behind the software.
- Proven PM Track Record: 3+ years of software product management experience in a biotech laboratory, ideally within a clinical setting.
- AI Fluency: Comfortable building AI tools and applying critical judgment to what they output and when AI-driven automation is worth building to drive efficiency, all while keeping product integrity, user needs, business goals, and privacy or regulatory requirements in mind.
- Clarity & Collaboration: Exceptional communication skills with a natural ability to translate complex technical/biological nuances into clear, actionable product needs.
- Execution Mindset: Highly organized and reliable. You thrive in ever-changing environments and have the backbone to make high-stakes, risk-based tradeoff decisions.

Pluses:

- CLIA/CAP and/or medical device experience.
- Some familiarity with SQL and relational databases, some simple programming abilities with any language.

Expected Interview Process:

1. Recruiter Screen 2) Manager Screen/Tech Screen 3) Onsite 4) Offer

Expected Pay For This Role: There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity

- Expected Helix Base: $144,000 - $189,000
- Expected Helix Discretionary Annual Bonus: 10% of your annual salary
- Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.

Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:

- Comprehensive Health Insurance with Date of Hire eligibility - Above average employer paid premium coverage
- 12 weeks Helix Paid Parental Leave option
- 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
- Comprehensive Well-Being Benefits
- Flexible PTO
- Remote options for many roles and a home office stipend

What To Expect During Your First 90 days:

- First 30 days: you’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You’ll also gain a deeper understanding of our customers, our products, the impact we make in the lives of our communities, and how to thrive at Helix through participation in Helix U.
- Day 30 - 60: you’ll spend time contributing to projects, deeply familiarizing yourself with team and company processes, and developing a deeper understanding of Helix’s products, services and capabilities.
- Day 60 - 90: you’ll build your OKRs with your manager, start to take ownership of projects and initiatives on your team, and begin to demonstrate your impact on the Helix mission.

To learn how Helix collects, uses, and protects your personal information during the recruitment process, please review our[Privacy Notice](https://www.helix.com/privacy-policy).

Helix is proud to be an equal opportunity employer, and committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth and breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, and local laws.

#LI-Remote

## About Helix

## Company Overview
- **One-liner**: Helix is a population genomics company that integrates DNA insights into clinical care, research, and therapeutic development at scale.
- **Entity Type**: Private (Grant stage; $283.9M total funding)
- **Headquarters**: San Mateo, California, United States
- **Founded**: 2015
- **Founders**: Not publicly listed on major sources (founded as HELIX HOLDINGS I, LLC)

## Core Business
- **Primary Industry**: Healthcare technology / Population genomics / Precision medicine
- **Target Customers**: Health systems, life sciences companies, health plans, and payers (B2B); also provides patient-facing genetic testing (B2C/D2C)
- **Mission**: “To empower every person to improve their life through their DNA.”

## Products & Services
- **Population Genomics Platform**: A Sequence Once, Query Often™ model enabling health systems to uncover genetic risk efficiently and integrate insights at the point of care. Includes clinical decision support, EHR integration, and patient engagement tools.
- **Genetic Testing Services**: Seamless test ordering for clinicians, with results integrated into clinical workflows. Covers diagnostic and screening applications.
- **Helix Research Network®**: A large-scale network connecting real-world genomic data from health systems and life sciences partners to accelerate discovery and drug development.

## Market Standing
- **Valuation**: Not publicly disclosed
- **Total Funding**: $283.9M raised to date (latest round: Grant - II, $900K, ~5 years ago)
- **Notable Investors**: Kleiner Perkins, Warburg Pincus, Temasek, DFJ Growth Fund, The Rockefeller Foundation, and 7 others
- **Key Customers/Partners**: Renown Health, Mayo Clinic, Medical University of South Carolina
- **Growth Signals**: 162 patents filed; operating at the intersection of clinical care and research; population-scale programs showing cost-effectiveness (per internal models); active in large health system deployments

## Competitive Advantages
- **Sequence Once, Query Often™ model**: A proprietary approach that reuses genomic data across multiple clinical and research use cases, reducing cost and friction.
- **Integrated platform**: Combines lab testing, clinical decision support, EHR integration, and research network into one cohesive offering—hard for competitors to replicate.
- **Proven health system partnerships**: Deployments with leading institutions like Mayo Clinic and Renown Health provide real-world validation and a defensible moat.
- **Patent portfolio**: 162 patents covering molecular biology, genetics, and bioinformatics.

## Strategic Focus
- Scaling population genomics programs across more health systems and payers
- Deepening integration with EHRs and clinical workflows to drive adoption
- Expanding the Helix Research Network to generate more real-world evidence
- Demonstrating cost-effectiveness and ROI to health plans to drive reimbursement

## Why Work Here
- **Mission-driven**: Directly contributing to improving lives through DNA—translating complex genomics into actionable health insights.
- **Collaborative culture**: Described as “curious and passionate,” with a focus on transparency, collaboration, and empowerment across science, engineering, design, and marketing.
- **Interdisciplinary team**: Genomics scientists, engineers, product developers, and researchers working together—no PhD required to geek out on genomics.
- **Growth stage company**: Private with significant funding and major partnerships, offering the excitement of a scale-up with real impact.
- **Location**: San Mateo, CA (Bay Area); customer support hours are Pacific time.
- **No explicit remote/hybrid policy found**, but standard tech company culture likely applies.

## Sources
1. [helix.com](https://www.helix.com/)
2. [helix.com/careers](https://www.helix.com/company/careers)
3. [helix.com/about](https://www.helix.com/v2/about)
4. [helix.com/our-team](https://www.helix.com/company/our-team)
5. [cbinsights.com](https://www.cbinsights.com/company/helix)

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