---
title: 'Regional Director, Site Engagement & Access at Definium Therapeutics'
canonical: 'https://feeny.ai/job/regional-director-site-engagement-access-definium-therapeutics-remote-svpfzm9r0a9n'
type: 'job'
last_seen: '2026-11-10'
---

# Regional Director, Site Engagement & Access at Definium Therapeutics

- **Company:** Definium Therapeutics
- **Location:** Remote
- **Compensation:** $195k–$285k
- **Work type:** remote
- **Posted:** 2026-11-05
- **Last confirmed live:** 2026-11-10
- **Apply:** https://job-boards.greenhouse.io/definiumtherapeutics/jobs/6249937004

## Job description

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!

We are seeking to hire 2 Regional Directors, Site Engagement & Access (East and West) to build and lead a field-based team responsible for advancing treatment site readiness, supporting operational implementation, and establishing the reimbursement capabilities necessary for successful & sustainable treatment delivery.

The Regional Director will lead a team of Site Engagement and Access Leads who serve as integrated resources to sites of care, supporting both operational readiness and reimbursement needs throughout the treatment journey.

This role requires strategic, hands-on leadership with experience in market access, field reimbursement, site of care activation and complex therapy launches. The successful candidate will translate national strategy into regional execution, build strong cross-functional partnerships, and drive measurable progress in site readiness, treatment implementation, and access & reimbursement effectiveness.

Responsibilities:

- Recruit, develop, coach and lead a compliant, high-performing team of Site Engagement and Access Leads responsible for both site readiness and ongoing reimbursement support
- Translate national strategy into regional priorities, execution plans and measurable objectives
- Oversee regional site engagement strategies to assess operational capabilities and identify barriers
- Guide team in supporting site workflows, staffing, scheduling, training requirements and applicable REMS requirements
- Ensure field teams effectively educate on coverage, coding, billing, and reimbursement processes, including buy-and-bill requirements
- Identify and escalate complex reimbursement barriers, emerging payer challenges, and site-level financial concerns
- Partner with Market Access, Patient Services, and other internal functions to develop solutions and improve site reimbursement capabilities
- Ensure field reimbursement activities remain within applicable regulatory, legal, and company compliance requirements
- Partner with Sales Leadership, Market Access, Medical Affairs, Training, Trade & Distribution, Patient Services, and other stakeholders to coordinate site engagement and access strategies
- Provide actionable regional insights regarding site capabilities, operational barriers, reimbursement challenges, and treatment implementation needs
- Support the development and refinement of field tools, training programs, reimbursement resources, and operational processes

Qualifications:

- Minimum bachelor’s degree required, degree in business, healthcare administration, life sciences, or a related field preferred
- Minimum 10 years of experience in pharmaceuticals, biotechnology, healthcare, or related industries required
- Minimum 5 years of experience in market access, field reimbursement, patient services, site-of-care management, or healthcare operations
- Launch experience is required
- Experience working in a small entrepreneurial type environment
- Demonstrated experience building, leading and developing field-based teams
- Strong understanding of healthcare delivery systems, provider operations, and complex treatment implementation
- Demonstrated knowledge of medical benefit reimbursement, including buy-and-bill models, coverage, coding, billing, and payer processes
- Proven ability to execute complex field strategies and influence cross-functional stakeholders
- Strong leadership, communication, analytical, and problem-solving skills
- Up to 75% travel may be required based upon business needs within an assigned region

Individual compensation within the range is determined based on factors such as relevant skills, experience, qualifications, scope of the role, and other legitimate business considerations.  In addition to base salary, this role may be eligible for bonus and equity opportunities. We also offer a comprehensive benefits package including health insurance, 401(k) with company match, flexible time off and additional wellness benefits and perks.  Learn more about our benefits on our Careers page.

The anticipated base salary range for this position is: $195,000—$285,000 USD

## About Definium Therapeutics

## Company Overview
- **One-liner**: Definium Therapeutics is a clinical-stage biopharmaceutical company applying scientific rigor to psychedelic medicine to develop accessible treatments for psychiatric disorders.
- **Entity Type**: Public (NASDAQ: DFTX)
- **Headquarters**: Not specified in available sources; the company operates as a remote-first organization.
- **Founded**: 2019 (originally as MindMed)
- **Founders**: Not publicly available in provided sources.

## Core Business
- **Primary Industry**: Biotechnology / Psychiatric drug development (psychedelic medicine)
- **Target Customers**: Patients with major depressive disorder (MDD), generalized anxiety disorder (GAD), posttraumatic stress disorder (PTSD), and autism spectrum disorder (ASD); also healthcare providers and payers.
- **Mission/Purpose**: “Unlock healing at scale” by harnessing the full therapeutic potential of psychedelic medicine through precise, evidence-based science.

## Products & Services
- **DT120 ODT (Lysergide/LSD D-Tartrate Oral Disintegrating Tablet)**: Investigational drug for GAD, MDD, and PTSD. Currently in four Phase 3 trials (Voyage, Panorama, Emerge, Ascend) and a fifth planned for PTSD. FDA Breakthrough Therapy Designation for GAD. No adjunctive psychotherapy required.
- **DT402 (R(-)-MDMA)**: R-enantiomer of MDMA selected for serotonergic properties with a potentially superior tolerability profile. In Phase 2a study for social communication challenges in autism spectrum disorder.

## Market Standing
- **Valuation/Market Cap**: Not publicly available (publicly listed on NASDAQ as DFTX as of 2026, but recent market cap not provided in search results).
- **Key Metric**: Pre-revenue clinical-stage company; total funding history not disclosed in available sources.
- **Notable Investors/Partners**: Not disclosed in provided sources.
- **Growth Signals**:
  - Five Phase 3 trials ongoing or planned for DT120 ODT.
  - FDA Breakthrough Therapy Designation for DT120 in GAD.
  - Phase 2a trial initiated for DT402 in ASD.
  - Full results from Phase 2b GAD trial published in JAMA (2025).
  - Strong intellectual property with issued patents covering formulation, manufacturing, and treatment.

## Competitive Advantages
- **Proprietary Formulations**: Pharmaceutically optimized ODT for LSD (DT120) and novel R-enantiomer of MDMA (DT402) with potential improved tolerability.
- **Scientific Rigor**: Standalone drug studies without psychotherapy, enabling clearer efficacy and safety data.
- **Regulatory Momentum**: FDA Breakthrough Therapy Designation and multiple IND clearances.
- **Experienced Management Team**: Proven track record in developing and commercializing CNS therapies.
- **Comprehensive IP Strategy**: Patents covering drug formulations, methods of manufacture, and treatment use.

## Strategic Focus
- **Late-Stage Pipeline Advancement**: Completing Phase 3 trials for GAD and MDD, initiating PTSD trial.
- **Pipeline Expansion**: Advancing DT402 for ASD and exploring additional neuropsychiatric indications.
- **Commercial Readiness**: Building infrastructure (hiring VP of Sales, Senior Director of Field VEOR, etc.) to support potential future launch.
- **Data Generation**: Generating high-quality evidence to support regulatory submissions and differentiation.

## Why Work Here
- **Remote-First Culture**: “You can live anywhere in the country you’re employed in” (remote-first workforce).
- **Comprehensive Benefits**: 100% paid medical, dental, vision for employees and dependents; FSA/HSA; life and disability insurance.
- **Wellness & Time Off**: Annual wellness allowance, flexible PTO, company-wide shutdowns for rest.
- **Family Support**: Paid parental leave for birthing and non-birthing parents, 2-week return-to-work transition.
- **Financial Wellness**: Competitive compensation, 401(k) with employer match, employee equity (new hire grants and refreshes), Employee Stock Purchase Plan (ESPP) with discount.
- **Mission-Driven Work**: Opportunity to contribute to groundbreaking treatments in psychedelic psychiatry with a science-driven, collaborative team.

## Sources
1. [definiumtx.com](https://definiumtx.com/) – Company overview and pipeline details
2. [definiumtx.com](https://definiumtx.com/story/) – Company history, leadership, and strategic milestones
3. [definiumtx.com](https://definiumtx.com/careers/) – Careers page with benefits and remote-first policy
4. [definiumtx.com](https://definiumtx.com/research-development/) – Research and development pipeline details
5. [linkedin.com](https://www.linkedin.com/company/definiumtherapeutics) – LinkedIn company page

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