--- title: 'Research Associate I/II at Freenome' canonical: 'https://feeny.ai/job/research-associate-i-ii-freenome-brisbane-b2v3jsj88dmn' type: 'job' last_seen: '2026-09-07' --- # Research Associate I/II at Freenome - **Company:** Freenome - **Location:** Brisbane, CA - **Work type:** onsite - **Posted:** 2026-07-24 - **Last confirmed live:** 2026-09-07 - **Apply:** https://job-boards.greenhouse.io/freenome/jobs/8637397002 ## Job description About this opportunity: At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early detection and intervention in human disease. As a Research Associate I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. Starting with a prototype assay, you will contribute to developing and validating clinical-grade assays to measure complex, blood-based analytes. You will work closely with multiple teams including molecular research, computational science, automation engineering, and clinical operations to develop the assays in a regulated, high-throughput environment as well as identify ways to rapidly iterate and improve on existing methods to evaluate technologies that can enhance our end-to-end test performance. The role reports to the Senior Manager and Staff Research Scientist. This role will be an Onsite role. What you’ll do: - Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA. - Characterize automated assays by generating and analyzing experimental data. - Gather high-quality data, take detailed notes, and openly communicate on lessons learned while performing experiments. - Collaborate with research team and computational biologists, understand how data reflect underlying molecular biology, and contribute to analyzing data and generating study conclusions. - Present data in cross functional teams. - Participate in troubleshooting efforts and design experiments with some supervisor guidance. - Help with process improvements across the lab by thinking critically about the execution of all experiments. Must haves: - Bachelors with 1+ years of relevant industry experience or Masters in molecular biology, or a related field. - Hands-on experience in NGS based assay development including sample preparation, library preparation, target capture, and sequencing. - Biological understanding of human cell-free nucleic acids, single-cell analysis methods, immunology, and/or cancer biology. - High attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as required. - Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities. - Ability to manual pipette with high confidence, accuracy, and precision. - Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines. Nice to haves: - Experience working in a regulated laboratory environment (CLIA, GLP/GCLP, IVD development). - Experience with automated platforms in plate-based, low-volume formats and/or microfluidics and experience working with automated liquid handlers. - Experience using ELN (electronic lab notebook) and LIMS (lab information management system). - Familiarity with programing in a scientific programming language (e.g., Python or R). Benefits and additional information: The US target range of our base hourly rate for new hires is $37.68 - $46.69. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered.  Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ [freenome.com/job-openings/](http://freenome.com/job-openings/) for additional company information. Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. Applicants have rights under Federal Employment Laws. - https://www.dol.gov/agencies/whd/posters/fmla - https://www.dol.gov/agencies/ofccp/posters - https://www.dol.gov/agencies/whd/posters/employee-polygraph-protection-act California applicants please review the CCPA Notice at Collection here: - https://www.freenome.com/ccpa-privacy-notice-for-freenome-california-job-applicants/ ## #LI-ONSITE ## About Freenome ## Company Overview - **One-liner**: Freenome is a biotechnology company developing blood-based multi-omics tests powered by machine learning to detect cancer in its earliest, most treatable stages. - **Entity Type**: Private (Late Stage) – raised over $2B in total funding; stock symbol FRNM (NASDAQ) is associated with a related SPAC entity but the operating company remains privately held [linkedin.com] - **Headquarters**: Brisbane, California, United States - **Founded**: 2014 - **Founders**: Riley Ennis (Co-Founder and Chief Product Officer) and others [freenome.com] ## Core Business - **Primary industry**: Biotechnology / Early Cancer Detection - **Target customers**: B2B (health systems, insurers, employers) and B2C (patients via healthcare providers) - **Mission**: To create tools that empower everyone to prevent, detect, and treat their disease, starting with early cancer detection. ## Products & Services - **Freenome Multi-Omics Blood Test (Colorectal Cancer)**: A next-generation blood test that uses a multi-omics platform (cell-free DNA, methylation, proteins, etc.) combined with machine learning to detect early-stage colorectal cancer and advanced adenomas. Type: Diagnostic test (IVD) – currently under clinical validation and regulatory review [freenome.com]. ## Market Standing - **Valuation / Market Cap**: Not publicly disclosed (private). Total funding of $2.07B (LinkedIn estimate) or $1.428B (CB Insights); conflicting reports reflect different counting methods [linkedin.com], [cbinsights.com] - **Key Metric (Funding)**: Most recent round – $75M corporate round (Nov 2025) led by Roche, plus $254M venture round (Feb 2024) also led by Roche [linkedin.com] - **Notable Investors**: Perceptive Advisors, RA Capital Management, Roche Venture Fund, Kaiser Permanente, Novartis, American Cancer Society’s BrightEdge Ventures, Exact Sciences [linkedin.com], [freenome.com] - **Growth Signals**: - Blood-based test included in updated American Cancer Society colorectal cancer screening guideline - Appointed industry veteran Rob Guigley as Chief Commercial Officer (2025) - Ongoing clinical programs for multiple cancer types - Employee headcount of 304 with 22 active job postings (as of mid-2025) [linkedin.com] ## Competitive Advantages - **Multi-omics + AI platform**: Combines multiple biological signals (DNA methylation, fragmentomics, proteins) with proprietary machine learning algorithms to achieve high sensitivity and specificity for early-stage cancer. - **Strong clinical program**: Rigorous multi-site studies and partnerships with leading health systems (e.g., Kaiser Permanente). - **Deep investor backing**: Long-term support from top healthcare investors and strategic partners (Roche, Exact Sciences) provides capital and commercial pathways. - **First-mover in multi-cancer blood screening**: Focus on colorectal cancer as first indication, with potential to expand to other cancers. ## Strategic Focus - **Clinical validation & regulatory approval**: Completing pivotal studies and preparing FDA submission for colorectal cancer test. - **Commercial launch preparation**: Building commercial team (hiring Strategic Account Executives, VP Revenue Cycle Management) and establishing relationships with payers and health systems. - **Platform expansion**: Extending multi-omics technology to additional cancer types (lung, pancreatic, etc.) through research programs. ## Why Work Here - **Mission-driven culture**: Employees are motivated by the opportunity to “outpace cancer” and make a tangible impact on patient lives. Values include integrity, empathy, trust, servant leadership, and striving for greatness [freenome.com]. - **Equity ownership**: Every U.S. full-time employee receives equity packages, aligning personal success with company milestones [freenome.com/careers]. - **Competitive benefits**: Comprehensive medical plans, wellness programs, generous PTO, 12 paid holidays, annual bonus opportunities, and market-based salaries [freenome.com/careers]. - **Collaborative environment**: Cross-functional teams across clinical, scientific, and business domains; emphasis on respect and inclusion [freenome.com/careers]. - **Work model**: Likely office-based in Brisbane, CA (hybrid flexibility not explicitly stated). The company has a physical lab and office presence. - **Engineering & science culture**: Opportunity to work with state-of-the-art multi-omics data, machine learning, and clinical trial design. The team includes senior ML scientists, computational biologists, and software engineers. ## Sources 1. [freenome.com](https://www.freenome.com/) – Company overview, leadership, values, products 2. [freenome.com/careers](https://www.freenome.com/careers/) – Benefits, culture, job openings 3. [linkedin.com/company/freenome](https://www.linkedin.com/company/freenome) – Employee count, revenue estimate, funding rounds, investor list, recent hires and departures 4. [cbinsights.com/company/freenome](https://www.cbinsights.com/company/freenome) – Funding total, company description, patent activity ## Other roles at Freenome - [Help Desk Specialist (Contractor)](https://feeny.ai/job/help-desk-specialist-contractor-freenome-brisbane-ypj66zndzpfp) — Brisbane, CA - [Senior Bioinformatics Research Engineer](https://feeny.ai/job/senior-bioinformatics-research-engineer-freenome-brisbane-jqm79zg6pz00) — Brisbane, CA - [Senior Development Scientist I](https://feeny.ai/job/senior-development-scientist-i-freenome-brisbane-q9tqegw3c6c4) — Brisbane, CA - [Senior Research Associate](https://feeny.ai/job/senior-research-associate-freenome-brisbane-tsgfk8fbvpav) — Brisbane, CA - [Computational Biologist](https://feeny.ai/job/computational-biologist-freenome-remote-989vnftsd0w5) - [Staff Computational Biologist](https://feeny.ai/job/staff-computational-biologist-freenome-remote-9yh259vcdkp1) - [Strategic Account Executive (South)](https://feeny.ai/job/strategic-account-executive-south-freenome-remote-yr0frzr784de) - [Senior Director, Real World Data (RWD)](https://feeny.ai/job/senior-director-real-world-data-rwd-freenome-remote-djm04bx8qkbm) - [Vice President, Product Management](https://feeny.ai/job/vice-president-product-management-freenome-brisbane-sk773jd0f1tq) — Brisbane, CA - [Research Scientist I/II](https://feeny.ai/job/research-scientist-i-ii-freenome-brisbane-t4ngtdsjkvhc) — Brisbane, CA