--- title: 'Research Scientist II - In Vivo Science at AbCellera' canonical: 'https://feeny.ai/job/research-scientist-ii-in-vivo-science-abcellera-vancouver-t05sv48rmhry' type: 'job' last_seen: '2026-10-16' --- # Research Scientist II - In Vivo Science at AbCellera - **Company:** AbCellera - **Location:** Vancouver, Canada - **Posted:** 2026-09-26 - **Last confirmed live:** 2026-10-16 - **Apply:** https://job-boards.greenhouse.io/abcellera/jobs/8005913003 ## Job description Each of us cares about someone who will need medicines. That’s why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients who need them. We pursue truth and scientific rigour and have the courage to work at the edge of the unknown. We are looking for a lab-based Research Scientist II to join our Vancouver team and become a bridge between our in vivo models and the biological insights that shape our pipeline’s future. Working alongside experienced pharmacologists, you will support the design, execution, and analysis of in vivo studies that reveal how our drug to candidates behave in physiologically relevant settings to  inform important go/no-go decisions on our programs. This is hands-on, detail-driven science, and your rigour and curiosity will play a direct role in getting new medicines closer to the patients who need them. ## How you might spend your days - Working with team members and project teams to define the preclinical in vivo strategy to advance pipeline programs from hit identification through candidate selection - Collaborating with the In Vivo Models Team to design, develop, and validate novel animal models to expand internal capabilities and capture complex disease biology - Designing, coordinating, and interpreting robust in vivo efficacy and pharmacology studies to generate efficacy data and build high confidence in lead candidate selection - Collaborating with in vitro biology, protein engineering, and pharmacokinetics (PK/PD) scientists, as well as external CROs, to execute translational studies to screen and optimize lead molecules and advance programs toward human clinical trials - Developing, performing, and supervising sample analysis to assess target engagement, biomarker modulation, and downstream pathway effects - Training and mentoring junior scientists in ex vivo experimental plans and analytical methodologies - Synthesizing and reporting complex research findings to internal program teams and senior leadership to enable clear, data-driven decisions We’d love to hear from you if - You have a PhD in pharmacology, immunology, or a related field with 2-5 years of relevant industry experience, or an MSc with 5-8 years of experience, including hands-on work in oncology, immuno-oncology, and biologics drug development - You have hands-on experience designing and interpreting in vivo pharmacology models to assess PK, PD, and efficacy of test articles - You have a strong understanding of research ethics specific to animal care - You are genuinely curious, with an interest in discussing innovative ideas in a highly collaborative, cross-functional and fast paced environment - You communicate scientific and/or technical concepts effectively, with an emphasis on application - You have a proven track record of independently identifying project needs and translating them into practical, well-executed solutions - You enjoy tackling complex biological questions and building datasets that help predict which therapies will succeed ## What we offer AbCellera’s hiring range for this role is CAD $95,000 - $112,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution. You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find a strong sense of community and connections across AbCellera through our work, clubs, and socials. ## About AbCellera Creating medicines is the most important work we can do. We are a clinical-stage biotechnology company focused on discovering and developing antibody-based medicines in the areas of endocrinology, women’s health, immunology, and oncology. We have built a platform for advancing antibody drug programs from target to clinic, and we are using it to build our internal pipeline. Today, our pipeline includes two drug candidates in clinical development, two preclinical development candidates (DCs) in Investigational New Drug (IND)-enabling activities, and more than 20 active discovery programs across multiple modalities and indications. We believe that when tenacious people share a vision and work together, they can truly have a positive impact. That’s why we hire for character and intelligence, not just for CVs or experience. We look for people with drive and energy. People we trust. People who need to know their days are being well spent. That their work really matters. In the end, our success will be measured by the impact of our medicines. To apply Please submit your application through our website and refer to Job ID 23402 in your cover letter. We receive a large volume of applications and are only able to contact those who are selected for an interview. All communication from our Talent Discovery team will come from an @abcellera.com email address. ## About AbCellera ## Company Overview - **One-liner**: AbCellera is a clinical-stage biotechnology company that discovers and develops antibody-based medicines using an integrated platform from target identification through clinical manufacturing. - **Entity Type**: Public (Nasdaq: ABCL) - **Headquarters**: Vancouver, British Columbia, Canada - **Founded**: 2012 (based on “14+ Years” on corporate site) - **Founders**: Carl Hansen, PhD (Chairman, CEO & President); Véronique Lecault, PhD (Director, CTO) – originally six scientists from an academic lab ## Core Business - **Primary industry**: Biotechnology – antibody therapeutics - **Target customers**: B2B partnerships with biopharma companies (historically) and now also developing its own pipeline for patients - **Mission**: “To create a pipeline of innovative antibody medicines.” ## Products & Services - **Platform Technology**: A fully integrated antibody discovery and development platform combining microfluidics, single-cell analysis, computational biology, and protein engineering. Used to generate antibodies against complex targets (GPCRs, ion channels, multipass membrane proteins). - **ABCL635**: A first-in-class antibody for non-hormonal treatment of vasomotor symptoms (hot flashes) associated with menopause. Targets NK3R. Currently in Phase 1/2 clinical trial. - **ABCL575**: An investigational monoclonal antibody for moderate-to-severe atopic dermatitis, targeting OX40L with Fc-silencing and half-life extension. Phase 1 trial initiated Q3 2025. - **ABCL688**: An antibody medicine targeting a multipass complex membrane protein for an undisclosed autoimmune indication. Entered IND-enabling studies in Q2 2025. - **Partnership Business**: Completed 100+ discovery programs with 40+ partners since 2015, generating passive royalty stakes in partner drug programs. ## Market Standing - **Valuation/Market Cap**: Not publicly available from provided sources (public company; check Nasdaq: ABCL for current cap) - **Key Metric**: Public company with ~600 employees; 100+ programs delivered; internal pipeline moving into clinic - **Notable Investors/Partners**: Not specified in sources (as a public company, institutional investors are listed in SEC filings) - **Growth Signals**: Shift from pure partnership model to advancing internal pipeline; first internal program (ABCL635) reached Phase 1/2; new 130,000 sq ft GMP manufacturing facility in Vancouver; headcount growth from six scientists to ~600 ## Competitive Advantages - **Integrated platform** that covers the entire antibody development chain from target to clinical manufacturing, reducing handoffs and accelerating timelines. - **Proprietary microfluidics and single-cell analysis** technologies that enable high-throughput screening of natural immune responses. - **Deep expertise in difficult targets** (GPCRs, ion channels, multipass membrane proteins) that are challenging for traditional antibody discovery. - **Built over a decade of partnerships** – the platform was refined through 100+ partnered programs, creating a robust technology base. ## Strategic Focus - Transitioning from a technology-partnership company to a clinical-stage biotech advancing its own pipeline. - Prioritizing internal and co-development programs in endocrinology / women’s health, immunology & inflammation, and oncology. - Building in-house clinical manufacturing capabilities (CMC) to support GMP production of drug substance and drug product. ## Why Work Here - **Culture**: Values “truth and scientific rigor,” independent thinking, and courage to work at the edge of the unknown. - **Team focus areas**: Discovery, Data Science / ML / IT / Engineering, Clinical Manufacturing, Quality, and more. - **Perks & benefits**: - Comprehensive health benefits (medical, dental, life, critical illness) - Equity ownership (stock options/RSUs) - Retirement savings (RRSP/401K) with no employee match required (North America) - Minimum 3 weeks vacation plus 2 company-wide closures per year - Active lifestyle allowance - Immigration and relocation assistance - Personal & professional development (workshops, conferences) - World-class labs, offices, and on-site gym - **Work policy**: Likely on-site in Vancouver given lab and manufacturing roles; specific remote/hybrid options not detailed in provided sources. ## Sources 1. [abcellera.com](https://www.abcellera.com/) 2. [abcellera.com/about](https://www.abcellera.com/about) 3. [abcellera.com/careers](https://www.abcellera.com/careers) 4. [abcellera.com/current-openings](https://www.abcellera.com/current-openings) 5. 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