---
title: 'Scientist I, mRNA, Process Development at ElevateBio'
canonical: 'https://feeny.ai/job/scientist-i-mrna-process-development-elevatebio-waltham-massachusetts-f06qj3k2ynxh'
type: 'job'
last_seen: '2026-09-11'
---

# Scientist I, mRNA, Process Development at ElevateBio

- **Company:** ElevateBio
- **Location:** Waltham Massachusetts, United States
- **Posted:** 2026-09-10
- **Last confirmed live:** 2026-09-11
- **Apply:** https://elevate.bio/about/jobs/6188496004?gh_jid=6188496004

## Job description

ElevateBio is a technology-driven company powering the industry forward by helping partners realize the potential of their therapies from design to commercialization. We have integrated a differentiated set of technologies, end-to-end services, and industry-leading manufacturing expertise to develop advanced therapies faster and more efficiently.

The Role:

We are seeking a highly skilled mRNA Scientist to join our process development team at ElevateBio. The ideal candidate will have extensive hands-on experience in mRNA synthesis, purification, and characterization. As an mRNA Scientist, you will be responsible for designing, executing, and optimizing experiments related to mRNA production and purification. You will work closely with cross-functional teams to support the tech transfer of mRNA-based therapeutics. Your contributions will be critical in advancing the manufacturing of mRNA-based products here at ElevateBio.

Here’s What You’ll Do:

- Lead the development, optimization, and scale-up experiments for mRNA based processes to achieve desired yields and purity
- Characterize mRNA samples using analytical techniques such as electrophoresis, spectrophotometry, and HPLC/UPLC to ensure product quality and consistency
- Work closely with cross-functional teams, including MSAT, analytical development, and external clients, to support project goals.
- Support the business development team in creating SOWs and proposals for external clients looking to partner for mRNA therapeutics
- Communicate experimental results and progress to internal stakeholders and external clients.
- Contribute to the development of standard operating procedures (SOPs) and technical documents.

Requirements:

Education Requirements

- BS/MS in Microbiology, Bioengineering, Biochemistry, or a related discipline with 8+ years of relevant experience, with a minimum of 4 years in working with mRNA-based therapeutics

## Experience Requirements

- Comprehensive mRNA processing experience with hands-on experience in in-vitro transcription (IVT) and plasmid DNA linearization.
- Knowledge in mRNA downstream methods for Tangential Flow Filtration (TFF) and multiple chromatography techniques such as dT Affinity, IEX, and RP-HPLC.
- Experience operating automated chromatography systems (ÄKTA Avant/Pure) and filtration skids (Repligen KrosFlow Kr2i).
- Comprehensive understanding of tech transfer activities around the production of mRNA drug substance
- Expertise in process scaling around mRNA production from bench scale to GMP manufacturing

## Preferred Qualifications

- Experience with mRNA-LNP formulation and mixing technologies/equipment
- Ability to use statistical software such as JMP for Design of Experiments (DoE) and data analysis.
- Familiarity with GMP regulations, Quality by Design principles, and preparing regulatory filing documentation.

The budgeted range for this position is $105,000 - $145,000. This range is a good faith estimate of the expected salary range for this position, based on a wide range of factors including qualifications, experience and training, operational and business needs and other considerations permitted by law. ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

## About ElevateBio

## Company Overview
- **One-liner**: ElevateBio is a technology-driven contract development and manufacturing organization (CDMO) that powers the creation of genetic medicines by providing integrated gene editing, process development, and cGMP manufacturing capabilities.
- **Entity Type**: Private (Series D – raised $401M in November 2025; total capital raised ~$1.3B)
- **Headquarters**: Waltham, Massachusetts, United States
- **Founded**: 2017
- **Founders**: Not publicly available

## Core Business
- Primary industry: Biopharmaceutical CDMO (cell and gene therapy, gene editing, mRNA therapeutics)
- Target customers: Biopharmaceutical innovators (B2B, enterprise)
- Mission: “To be the world’s most indispensable advanced therapy technology company, changing how companies operate, how products are created, and how disease is treated.”

## Products & Services
- **Gene Editing Tools & Discovery Services**: One of the world’s largest toolboxes of gene editing technologies (e.g., CRISPR enzymes), enabling flexible editing and broad access to the genome. Includes discovery services to move from target to optimized therapeutic candidate.
- **Process Development**: Scalable, robust manufacturing process design from preclinical through commercial scale.
- **Manufacturing (cGMP)**: Viral vectors, cell therapies, mRNA therapeutics, and lipid nanoparticles (LNP). Multi-modality capabilities with 98% batch success rate. Automated cell therapy manufacturing platform.
- **Regulatory Support & Commercialization**: Navigate CMC regulatory strategy from IND through BLA.
- **Next-Generation Sequencing / Rapid Analytics**: In-house analytics for quality and characterization.

## Market Standing
- **Valuation/Market Cap**: Not disclosed (private company)
- **Key Metric**: Total funding ~$1.3 billion (as of Series D close in November 2025)
- **Notable Investors/Partners**: Novo Nordisk (multi-target R&D collaboration worth up to ~$1.9B), Amazon Web Services (generative AI for CRISPR discovery), Sartorius (automated cell therapy platform), University of Pittsburgh / Richard King Mellon Foundation ($100M grant for biomanufacturing facility)
- **Growth Signals**: CNBC Disruptor 50 in 2021, 2023, 2024, 2025; Fast Company’s 2024 Most Innovative Companies; Boston Globe Top Place to Work (2022, 2023); first genetic medicines manufacturer to achieve ICMC multi-modality certification; opened flagship purpose-built biomanufacturing facility in Waltham, MA; achieved 98% manufacturing batch success rate across cell therapy, viral vector, and mRNA batches.

## Competitive Advantages
- **Integrated Model**: Science, process development, manufacturing, and quality operate under one roof – no hand-offs between stages.
- **Continuous Technology Investment**: Automation, AI-assisted design, and process innovation embedded as a permanent operating principle to reduce costs and timelines.
- **Multi-Modality Expertise**: Covers viral vectors, cell therapies, mRNA, LNP delivery, and gene editing – enabling partners to switch modalities without restarting.
- **Proprietary Gene Editing Toolbox**: Acquired Life Edit Therapeutics, adding one of the largest collections of gene editing enzymes and patents.
- **Industry-Leading Quality**: ICMC certification across multiple modalities and 98% batch success rate exceed industry standards.

## Strategic Focus
- Expand gene editing capabilities and delivery technologies (e.g., LNP in vivo delivery for nuclease editing).
- Scale manufacturing capacity through new facilities (Waltham flagship, Pittsburgh site).
- Deepen collaborations with pharma (Novo Nordisk) and tech (AWS) to accelerate therapy development.
- Apply generative AI to broaden CRISPR discovery for complex monogenic and polygenic diseases.
- Establish manufacturing blueprints for novel modalities such as base-edited therapies.

## Why Work Here
- **Culture**: Described as a group of “explorers” passionate about constant discovery, new technology, and progress in life-transforming therapies.
- **Benefits**: Medical, vision, and dental covered at 90%; low deductible; employer-paid life insurance and disability; 401(k) with 4% match (no vesting); 12 weeks parental leave; competitive PTO; commuter reimbursement; monthly cell phone stipend; fitness reimbursement; access to wellness apps.
- **Development**: LinkedIn Learning access, Insights Discovery training, ongoing professional development and manager training.
- **Work Environment**: Roles primarily based in Waltham, MA (on-site for manufacturing and lab positions). Hybrid/remote not explicitly stated but likely limited for operational roles.
- **Recognition**: Boston Globe Top Place to Work; named to CNBC Disruptor 50 multiple years.

## Sources
1. [elevate.bio](https://elevate.bio/)
2. [elevate.bio/about](https://elevate.bio/about/)
3. [elevate.bio/about/careers](https://elevate.bio/about/careers/)
4. [elevate.bio/about/our-journey](https://elevate.bio/about/our-journey/)
5. [LinkedIn](https://www.linkedin.com/company/elevatebio)

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