---
title: 'Scientist, In Vivo Biology at Altos Labs'
canonical: 'https://feeny.ai/job/scientist-in-vivo-biology-altos-labs-san-diego-knkjj1wwr991'
type: 'job'
last_seen: '2026-09-10'
---

# Scientist, In Vivo Biology at Altos Labs

- **Company:** Altos Labs
- **Location:** San Diego, CA
- **Posted:** 2026-07-20
- **Last confirmed live:** 2026-09-10
- **Apply:** https://job-boards.greenhouse.io/altoslabs/jobs/6114500004

## Job description

## Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at [altoslabs.com.](https://altoslabs.com/)

Our Value

Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.

Diversity at Altos

Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list.  At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.

## What You Will Contribute To Altos

We are seeking an exceptional and versatile Scientist to join Discovery Science at Altos Labs. This role is ideal for a creative experimental scientist with deep expertise in in vivo and ex vivo disease biology who is excited to characterize and validate novel interventions for improving cell resilience and rejuvenating tissue functions.

The successful candidate will help develop and apply animal disease models for characterizing novel interventions, with opportunities to contribute across areas such as target discovery and validation, in vivo screening, and tissue-level functional assessment.

We are looking for broadly capable scientists with strong technical depth, scientific creativity, and the curiosity to pursue new biological frontiers in a highly collaborative environment.

## Responsibilities

- Design and execute innovative research strategies to identify causal regulators of cell state, aging, regeneration, and disease biology.
- Develop and apply robust experimental workflows connecting genetic perturbation to molecular and phenotypic readouts across cellular and animal models.
- Support genomic and molecular profiling methods, including transcriptome, proteome and single-cell readouts, to uncover novel biological mechanisms.
- Translate in vitro discoveries into in vivo systems through the design and execution of hands-on mouse studies in relevant disease models.
- Collaborate closely with computational scientists and cross-functional teams to integrate multidimensional datasets and generate actionable biological insight.
- Lead project strategy, experimental design, execution, troubleshooting, and data interpretation.
- Contribute to publications, patents, and broader scientific strategy.

## Who You Are

- PhD in Biology, Stem cell, Aging, Physiology, or related field, with relevant postdoctoral and/or industry experience preferred.
- Strong track record of scientific accomplishment through publications, patents, or impactful platform development.
- Demonstrated expertise in the following areas:
- Hands-on in vivo experience with disease mouse models.
- Disease cell and mechanistic biology
- Ability to independently lead complex research projects from concept to execution.
- Strong analytical skills and ability to derive biological insight from multidimensional datasets.
- Excellent written and verbal communication skills.
- Demonstrated ability to work effectively in highly collaborative, interdisciplinary environments.
- Scientific rigor, creativity, and comfort operating in rapidly evolving areas.

## Minimum Qualifications

- Experience in small rodent handling, with an ability to independently design and coordinate the execution of complex in vivo studies, including drug administration, tissue harvest and processing.
- Expertise in physiologically relevant mouse models for chronic diseases.
- Hands-on experience with in vivo delivery modalities such as AAV, LNP, or related delivery systems.
- Experience or interest in studying novel biological mechanisms and emerging areas of biology.

## Preferred Qualifications

- Background in aging biology, regeneration, fibrosis, inflammation, metabolic disease, neurodegeneration, or related therapeutic areas.
- Direct experience with in vivo lung, kidney, or liver disease models.
- Hands-on experience generating and maintaining ex vivo precision-cut tissue slices.
- Experience with tissue-level genomics assays and analyses

The salary range for San Diego:

- Scientist I $127,100 - $162,900
- Scientist II $143,800- $184,300

## #LI-NN1

Exact compensation may vary based on skills, experience, and location.

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice ([bit.ly/eu_uk_privacy_notice](https://bit.ly/eu_uk_privacy_notice))
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

## Equal Opportunity Employment

We value collaboration and scientific excellence.

We believe that a culture of belonging are foundational to scientific innovation and inquiry. At Altos Labs, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining an inclusive environment.

Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.

Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/

## About Altos Labs

## Company Overview
- **One-liner**: Altos Labs is a biotechnology company pioneering cellular rejuvenation programming to reverse disease, injury, and disabilities by restoring cell health and resilience.
- **Entity Type**: Private (believed to be well-funded by high-profile investors including Jeff Bezos and Yuri Milner; no public funding rounds listed)
- **Headquarters**: San Francisco Bay Area, CA, USA (also major sites in San Diego, CA and Cambridge, UK)
- **Founded**: 2021 (publicly launched in January 2022)
- **Founders**: Hal Barron (CEO), Hans Bishop (President), Rick Klausner (Chief Scientific Advisor)

## Core Business
- **Primary industry**: Biotechnology / Longevity & Cell Rejuvenation / Drug Discovery
- **Target customers**: B2B/Institutional (partners, academic collaborators); ultimate end-users are patients with age-related diseases
- **Mission statement**: “To restore cell health and resilience through cell rejuvenation to reverse disease, injury and the disabilities that can occur throughout life.”

## Products & Services
Currently in the research and preclinical/early clinical stage. No marketed products yet. Major initiatives include:

- **[Cell Rejuvenation Programming Platform]**: Proprietary technology based on partial cellular reprogramming (building on Yamanaka factors and Belmonte lab discoveries) to reset epigenetic age and restore cell function.
- **[Institute of Computation]**: Developing multi-scale generative AI models to decode the “language of cell health” and accelerate discovery of rejuvenation-based therapies.
- **[Institute of Medicine]**: Translational arm focused on converting fundamental biology into potential breakthrough medicines for age-related diseases.
- **[Discovery Engine]**: Integrated platform combining experimental biology, high-quality internal data generation, and computational modeling to identify novel targets and therapies.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed; widely reported to have raised over **$3 billion** in initial financing (one of the largest biotech startup financings ever). Investors include Jeff Bezos, Yuri Milner, and others.
- **Key Metric**: **$3+ billion total funding** (reported launch round)
- **Notable Investors/Partners**: Jeff Bezos (via Bezos Expeditions), Yuri Milner (via DST Global), and other undisclosed high-net-worth individuals; partnerships with leading academic institutions including the Salk Institute and Cambridge University.
- **Growth Signals**: Rapidly scaling headcount (26 open roles listed on Greenhouse as of mid-2026); expansion of computational and AI teams; launched Institute of Computation; appointed Joan Mannick (M.D.) as Chief Medical Officer in 2025 to lead early clinical development.

## Competitive Advantages
- **Massive capital base**: Over $3 billion in funding provides long runway for high-risk, long-horizon science.
- **World-class scientific leadership**: CEO Hal Barron (ex-GSK, ex-Roche), President Hans Bishop (ex-Juno Therapeutics), Chief Scientific Advisor Rick Klausner, and founding scientist Juan Carlos Izpisua Belmonte (pioneer of partial reprogramming).
- **“Academic freedom meets industry focus” model**: Combines the freedom of academic inquiry with the discipline and resources of a biotech company.
- **AI-first approach**: Dedicated Institute of Computation with a focus on generative AI and foundational models for biology, differentiating from traditional drug discovery.
- **Multi-site global footprint**: Operations spanning US (Bay Area, San Diego) and UK (Cambridge) attract top talent from both sides of the Atlantic.

## Strategic Focus
- **Near-term**: Advancing first therapeutic programs into clinical trials; building out the Institute of Computation and AI models; scaling drug discovery and development capabilities.
- **Long-term**: Transform medicine by developing therapies that address the root cause of disease—cellular aging—rather than just symptoms.

## Why Work Here
- **Mission-driven culture**: Focus on a single, ambitious goal—reversing disease through cell rejuvenation—unites the organization.
- **Unique work model**: Blends academic freedom (pursue deep questions, publish, collaborate openly) with industry urgency (focus on medicines, milestones, patient impact).
- **Computational focus**: Heavy investment in AI/ML (machine learning scientists, AI engineers, computational biology) makes it appealing for those interested in the intersection of tech and biology.
- **Work environment**: Collaborative, interdisciplinary, and global; values diverse perspectives. Described as “a unique and inspiring place to work” with “many ways to contribute to our mission.”
- **Currently hiring across multiple disciplines**: Discovery Science, Drug Development, Computation, Technology, and Operations—with roles in San Francisco Bay Area, San Diego, and Cambridge, UK.
- **Perks/culture highlights**: Not explicitly detailed on careers page, but the emphasis on “freedom to collaborate broadly” and “big questions” suggests a high-autonomy, high-trust environment.

### Company Website & Careers
1. [altoslabs.com](https://www.altoslabs.com/) – Official company site (overview, science, about, careers)
2. [altoslabs.com/careers](https://www.altoslabs.com/careers) – Careers page (mission, culture, job listings)
3. [altoslabs.com/about](https://www.altoslabs.com/about) – About page (leadership, institutes, model)
4. [altoslabs.com/science](https://www.altoslabs.com/science) – Science page (founding science, partial reprogramming)

### Job Board
5. [job-boards.greenhouse.io/altoslabs](http://job-boards.greenhouse.io/altoslabs) – Greenhouse job board (26 open positions as of mid-2026)

## Other roles at Altos Labs

- [Scientist / Senior Scientist, Structural Cell Biology](https://feeny.ai/job/scientist-senior-scientist-structural-cell-biology-altos-labs-san-francisco-bay-2as6grjx00j9) — San Francisco Bay Area, CA
- [Neuroscience Research Associate / Research Specialist](https://feeny.ai/job/neuroscience-research-associate-research-specialist-altos-labs-san-francisco-r0jg5an2qvkn) — San Francisco Bay Area, CA
- [Scientist, Neurodegeneration](https://feeny.ai/job/scientist-neurodegeneration-altos-labs-san-francisco-bay-area-ptan9vfe9dfh) — San Francisco Bay Area, CA
- [Senior Research Associate, Drug Discovery](https://feeny.ai/job/senior-research-associate-drug-discovery-altos-labs-san-francisco-bay-area-es0k39mddn6n) — San Francisco Bay Area, CA
- [Director /  Senior Director, Machine Learning for Biology](https://feeny.ai/job/director-senior-director-machine-learning-for-biology-altos-labs-san-diego-tav9vfz1h2qf) — San Diego, CA / San Francisco Bay Area, CA
- [Scientist I, Disease Biology](https://feeny.ai/job/scientist-i-disease-biology-altos-labs-san-francisco-bay-area-et5derm8tk55) — San Francisco Bay Area, CA
- [Research Specialist / Scientist, Assay Development](https://feeny.ai/job/research-specialist-scientist-assay-development-altos-labs-san-francisco-bay-mh03x0h22xn9) — San Francisco Bay Area, CA
- [Research Specialist / Scientist, Metabolic Phenotyping (In Vitro & In Vivo)](https://feeny.ai/job/research-specialist-scientist-metabolic-phenotyping-in-vitro-in-vivo-altos-labs-5t2sm6dhx8vq) — San Francisco Bay Area, CA
- [Business and Laboratory Operations Manager, Drug Discovery & Development Sciences](https://feeny.ai/job/business-and-laboratory-operations-manager-drug-discovery-development-sciences-ndphgkvmg07w) — San Francisco Bay Area, CA
- [Senior Counsel II / Corporate Counsel, Transactions](https://feeny.ai/job/senior-counsel-ii-corporate-counsel-transactions-altos-labs-san-francisco-bay-z6yn7t54afpe) — San Francisco Bay Area, CA