---
title: 'Scientist, LNP-Drug Product Development at NewLimit'
canonical: 'https://feeny.ai/job/scientist-lnp-drug-product-development-newlimit-south-san-francisco-nyvhkqvmdezz'
type: 'job'
last_seen: '2026-09-11'
---

# Scientist, LNP-Drug Product Development at NewLimit

- **Company:** NewLimit
- **Location:** South San Francisco, CA
- **Posted:** 2026-07-29
- **Last confirmed live:** 2026-09-11
- **Apply:** https://job-boards.greenhouse.io/newlimit/jobs/6129296004

## Job description

Company info

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat aging by reprogramming the epigenome, a new therapeutic mechanism to restore youthful function in aged cells. We’ve built the world’s leading experimental and artificial intelligence system to discover reprogramming medicines at massive scale. Our first products are focused on restoring youthful metabolic, endothelial, and immune function.

Description

NewLimit is seeking a Scientist to join our Delivery Sciences team. In this role, you will development formulations, purification processes, and characterization methods for lipid nanoparticle (LNP) drug products. NewLimit’s reprogramming medicines rely upon these LNP chemistries to carry reprogramming payloads to target cells and tissues throughout the body.

The ideal candidate possesses a deep technical understanding of LNP assembly via various mixing methods, expertise in downstream purification, and hands-on experience with advanced analytical characterization techniques.

## What you’ll do

- Formulate, purify, and characterize LNPs for nucleic acid delivery
- Collaborate with the Epigenetic Editing and Product teams (Immunology, Metabolism, Vascular) to develop LNP-RNA reprogramming medicines.
- Develop and optimize LNP compositions to target new cell types for reprogramming.
- Interpret complex experimental data and perform statistical analyses to reach robust conclusions.
- Maintain rigorous and detailed records of experimental protocols and results in an Electronic Laboratory Notebook (ELN).

## Requirements

- Ph.D. in Biomedical Engineering, Chemical Biology, Pharmaceutical Sciences, or a related discipline or equivalent industry experience
- Experience formulating LNPs with diverse lipid components for nucleic acid delivery
- Experience with purification techniques, including dialysis, Tangential Flow Filtration (TFF), ultracentrifugation, and sterile filtration.
- Proficiency in LNP analysis using dynamic or multi-angle light scatting, liquid chromatography, and standard molecular biology assays (ELISA, qPCR, spectroscopy).

## Nice to have

- Experience contributing to drug product development at the preclinical or clinical stages.
- Background in extra-hepatic nucleic acid delivery.
- Experience with bioconjugation, surface modification, or targeted LNP formulation.
- Experience with data visualization and statistical analysis (R, Python)

## Benefits

NewLimit provides generous benefits so our team can remain focused on our mission:

- Comprehensive Health, Dental, and Vision insurance.
- 401(k) plan with company match.
- Paid parental leave.
- Industry-leading PTO**:** 20 days per year plus holidays.
- On-site meals and snacks.

Salary Range: $113,000 to $171,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers   *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.

## About NewLimit

## Company Overview
- **One-liner**: NewLimit is a biotechnology company developing epigenetic reprogramming medicines to radically extend human healthspan by reversing cellular aging.
- **Entity Type**: Private (Series B)
- **Headquarters**: South San Francisco, California, United States
- **Founded**: 2022
- **Founders**: Jacob Kimmel (Co-founder & President), Brian Armstrong (Co-founder), Blake Byers (Co-founder)

## Core Business
- **Primary industry/industries**: Biotechnology, Epigenetic Reprogramming, Longevity Therapeutics, Drug Discovery
- **Target customers**: B2B (pharmaceutical partners, clinical development), B2C (ultimately patients with age-related diseases)
- **Mission or purpose statement**: To radically extend human healthspan by creating the first medicines that reverse cellular aging at the epigenetic level.

## Products & Services
- **Discovery Engine**: An AI-powered platform that designs epigenetic payloads to make old cells look and act young. It tests thousands of designs simultaneously using genomics and retrains models iteratively on new data.
- **Therapeutics (Pipeline)**: Medicines focused on restoring youthful function in the liver, immune system, and vasculature. Initial programs target diseases resembling accelerated aging, with the goal of restoring youthful metabolism, energy levels, resilience to disease, and cognition.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed
- **Key Metric**: Total Funding of **$215M** (across three rounds); Annual Revenue estimated at **$12.8M** [linkedin.com](https://linkedin.com/company/newlimit)
- **Notable Investors/Partners**: Kleiner Perkins (led Series B), Valor Equity Partners, Quiet Capital, S32, Duke University Management Company, Liberty Mutual Investments, Fred Ehrsam, Elad Gil, Joe Lonsdale, Eric Schmidt, Garry Tan, Brian Armstrong, Blake Byers [newlimit.com](https://www.newlimit.com/company)
- **Growth Signals**: 44 employees (+40.5% YoY), 12 active job postings (+100% YoY), LinkedIn followers grew 157.6% in the past year, and the company closed a $130M Series B in May 2025 led by Kleiner Perkins [linkedin.com](https://linkedin.com/company/newlimit).

## Competitive Advantages
- **Proprietary AI Platform**: A frontier intelligence system that designs, tests, and retrains models on epigenetic reprogramming at unprecedented scale.
- **Scientific Moats**: Deep expertise in epigenetic reprogramming (a validated but complex mechanism for reversing cellular age); a team with backgrounds from Calico, UCSF, and Stanford.
- **Founding Team & Backing**: Co-founded by Brian Armstrong (CEO of Coinbase) and Blake Byers (early investor in OpenAI, Anthropic, Neuralink), providing deep capital access and a culture of ambitious, long-term execution.

## Strategic Focus
- **Current priorities**: Advancing pipeline programs into the clinic (Head of Clinical Development role is open); scaling the Discovery Engine; building the team across computational biology, immunology, and manufacturing.
- **Direction for growth**: Transition from a discovery-stage R&D company to a clinical-stage therapeutics company; generating large revenue streams to fund the mission; expanding into new cell types and disease areas.

## Why Work Here
- **Culture**: "Not for the faint of heart" — a high-performance, mission-focused team. No pure management roles; everyone executes. Values include safety then speed, clear communication, inherent optimism, independent thinking, and top talent in every seat [newlimit.com](https://www.newlimit.com/careers).
- **Remote/Hybrid/Office**: Likely on-site/hybrid given the lab-based nature of the work (headquarters in South San Francisco).
- **Notable Perks**: Competitive salaries, comprehensive health benefits (medical, dental, vision), equity packages, 401(k) with up to 4% match, generous parental leave, 20 days PTO + 15 holidays, free EV charging [newlimit.com](https://www.newlimit.com/careers).
- **Engineering Culture**: Strong emphasis on computational biology, machine learning, and functional genomics. The team spans both wet-lab and dry-lab disciplines, with a focus on building scalable methods and iterative data-driven discovery.

## Sources
1. [NewLimit Website](https://www.newlimit.com/)
2. [NewLimit Careers Page](https://www.newlimit.com/careers)
3. [NewLimit Company Page](https://www.newlimit.com/company)
4. [NewLimit Team Page](https://www.newlimit.com/team)
5. [NewLimit LinkedIn Page](https://www.linkedin.com/company/newlimit)

## Other roles at NewLimit

- [Senior Scientist / Scientist, In Vivo Pharmacology](https://feeny.ai/job/senior-scientist-scientist-in-vivo-pharmacology-newlimit-south-san-francisco-t4a3w08ps5rd) — South San Francisco, CA
- [Senior Manager, Lab Operations](https://feeny.ai/job/senior-manager-lab-operations-newlimit-south-san-francisco-2s9yfb1zrv9n) — South San Francisco, CA
- [Scientist, LNP-Lipid Chemistry](https://feeny.ai/job/scientist-lnp-lipid-chemistry-newlimit-south-san-francisco-dhqb4z5sh4rw) — South San Francisco, CA
- [VP/Senior Director, Clinical Operations](https://feeny.ai/job/vp-senior-director-clinical-operations-newlimit-south-san-francisco-3myq4z294a7c) — South San Francisco, CA
- [Laboratory Operations Specialist](https://feeny.ai/job/laboratory-operations-specialist-newlimit-south-san-francisco-mf010pr8xwk8) — South San Francisco, CA
- [Executive Recruiter](https://feeny.ai/job/executive-recruiter-newlimit-south-san-francisco-gyv2et7crq90) — South San Francisco, CA
- [Executive Assistant](https://feeny.ai/job/executive-assistant-newlimit-south-san-francisco-jznmrqh4wrvw) — South San Francisco, CA
- [IT & Security Lead](https://feeny.ai/job/it-security-lead-newlimit-south-san-francisco-zdar0wnmwbkn) — South San Francisco, CA
- [Senior/Research Associate, Functional Genomics](https://feeny.ai/job/senior-research-associate-functional-genomics-newlimit-south-san-francisco-09h6rva4fp46) — South San Francisco, CA
- [Scientist, Drug Product Analytical](https://feeny.ai/job/scientist-drug-product-analytical-newlimit-south-san-francisco-x377jpajt45d) — South San Francisco, CA