--- title: 'Scientist, Membrane Protein at Superluminal Medicines, Inc.' canonical: 'https://feeny.ai/job/scientist-membrane-protein-superluminal-medicines-inc-boston-1xpt5v22wx42' type: 'job' last_seen: '2026-10-14' --- # Scientist, Membrane Protein at Superluminal Medicines, Inc. - **Company:** Superluminal Medicines, Inc. - **Location:** Boston, MA - **Posted:** 2026-10-06 - **Last confirmed live:** 2026-10-14 - **Apply:** https://job-boards.greenhouse.io/superluminalrx/jobs/5445109008 ## Job description About Superluminal Medicines: Superluminal Medicines is a generative biology and chemistry company revolutionizing the speed and accuracy of how small molecule medicines are created. The Company’s platform aims to create candidate-ready compounds with unprecedented speed using a combination of deep biology, computational and medicinal chemistry, machine learning, and proprietary big data infrastructure. We are expanding the team of talented scientists who seek to build the future of small molecule drug discovery with creativity and innovation. Position Summary We are seeking a highly innovative and experienced Scientist to drive membrane protein production efforts. The successful candidate will be a subject matter expert (SME) in membrane protein biochemistry, responsible for developing and implementing strategies to express, purify, and characterize challenging G-protein coupled receptors (GPCRs) to support structural biology, biophysics, and biochemistry across drug discovery programs. This role focuses on hands-on laboratory work and provides opportunities for scientific leadership to shape Superluminal's platform and drug discovery projects. ## Key Responsibilities - Design, produce, and optimize membrane protein constructs that increase the success rates of small-molecule therapeutic discovery programs. - Drive the development of high-throughput protein expression (mammalian/insect cells) and purification workflows, ensuring high-quality, homogeneous protein for assays and structural studies (Cryo-EM). - Partner with pharmacology, structural biology, and medicinal chemistry teams to support drug discovery projects and advance programs from hit finding to lead optimization. - Serve as a SME on membrane protein expressions on internal and external project teams; evaluate and implement new technologies. - Document experiments in ELN, present data and strategies to internal/external audiences. Required Qualifications - Bachelor’s degree in Biochemistry, Molecular Biology, Biophysics, or a related field with 8+ years of relevant experience, a Master’s degree with 5+ years of experience, or a Ph.D. with 2+ years of experience - 2+ years of working experience in the biotech or pharmaceutical industry. - Experience in molecular biology (cloning, construct design, mutagenesis). - Experience in protein stabilization techniques (e.g., antibody fragments, fusion partners, mutagenesis). ## Preferred Qualifications - 5+ years of membrane protein expression and purification. - Experience in protein purification of GPCRs using FPLC (e.g. affinity, SEC). - Experience with structural biology methods (e.g. data collection and Cryo-EM). - Experience in laboratory automation in protein sciences & purification. - Experience in computational protein design tools (e.g., Rosetta, AI/ML-driven prediction). Pay Range $125,000 - $139,902 The annual base salary range listed above represents the lowest and highest amounts we reasonably and in good faith expect to pay for this position at the time of posting. An individual’s starting base salary within this range will be based on relevant experience, job-related skills, and education relevant to the role. In addition to base salary, this position offers bonus and equity opportunities, as well as benefits. Benefits: Superluminal offers a comprehensive benefits package that fully covers employees’ annual deductibles and monthly premiums for medical, dental, and vision insurance. The package also includes a 401(k) match program, a Massachusetts transportation subsidy, equity, unlimited paid time off, and both disability and life insurance. Equal Opportunity Statement: Superluminal Medicines is an Equal Opportunity Employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status. ## About Superluminal Medicines, Inc. ## Company Overview - **One-liner**: Superluminal Medicines is a drug discovery company integrating AI/ML, protein dynamics, and structural biology to rapidly develop small molecule therapeutics targeting challenging G protein-coupled receptors (GPCRs) for cardiometabolic diseases and obesity. - **Entity Type**: Private (Convertible Note financing round; total funding $158M as of 2026) - **Headquarters**: Boston, Massachusetts, United States (15 Necco Street, 4th Floor) - **Founded**: 2022 - **Founders**: Not publicly disclosed ## Core Business - **Primary Industry**: Biotechnology / Drug Discovery & Development - **Target Customers**: B2B partnerships with large pharmaceutical companies (e.g., Eli Lilly) and, ultimately, patients with cardiometabolic conditions and obesity - **Mission / Purpose**: “Revolutionizing the speed and accuracy of how medicine is created” by combining generative biology and chemistry with AI-driven computational methods. ## Products & Services - **Hyperloop™ Platform**: An integrated drug discovery platform that merges structure-based drug discovery, machine learning, proprietary big data infrastructure, and experimental validation to generate candidate-ready small molecule compounds targeting GPCRs. (SaaS/internal tool – not sold externally) - **Pipeline – MC4R Agonist**: A selective, biased MC4R agonist advancing to IND-enabling studies for the treatment of obesity. - **Other pipeline programs**: Undisclosed GPCR targets for cardiometabolic diseases, developed in collaboration with Eli Lilly. ## Market Standing - **Valuation**: Not publicly available - **Key Metric**: Total funding raised – $158M (CB Insights estimate) - **Notable Investors/Partners**: Eli Lilly and Company (collaborator and equity investor), RA Capital Management, Insight Partners, Gaingels, NVentures (NVIDIA’s venture arm) - **Growth Signals**: - Announced a multi-target collaboration with Eli Lilly worth up to $1.3B in upfront, near-term, milestone payments, equity investment, and tiered royalties. - Biased MC4R agonist moving into IND-enabling studies. - Active hiring: 5+ open positions in Machine Learning, Protein Design, Computational Chemistry, HR, and Finance. ## Competitive Advantages - **Hyperloop Platform**: Combines deep biology/chemistry expertise with AI and proprietary big data in a single, rapid iteration cycle – enabling candidate-ready compounds at unprecedented speed. - **GPCR Focus**: Specialization in the most challenging GPCR targets, a proven class for drug development but historically difficult to modulate selectively. - **Big Pharma Backing**: Strategic collaboration with Eli Lilly provides significant funding, validation, and potential for rapid clinical development. ## Strategic Focus - Advance the MC4R agonist and other pipeline candidates through IND-enabling studies and into clinical trials. - Expand the Hyperloop platform’s application to additional GPCR targets and disease areas beyond cardiometabolic indications. - Leverage AI/ML and structural biology to compress traditional drug discovery timelines from years to months. ## Why Work Here - **Culture**: Core values emphasize urgency (speed to patients), resilience, collaboration, transparency, and compassion. The team describes the environment as inclusive, collaborative, and supportive. - **Work Policy**: Primarily onsite at a brand-new lab space in Boston’s Seaport area (Lilly Gateway Labs). Remote/hybrid flexibility is not explicitly stated. - **Benefits**: 100% employer-paid health/dental/vision insurance, equity participation, 401k, unlimited paid time off, and a subsidy for parking or mass transit. - **Engineering & Science Culture**: Opportunities to work at the intersection of AI/ML, computational chemistry, and structural biology in a well-funded, fast-moving biotech startup with direct pharma partnerships. ## Sources 1. [superluminalrx.com](https://www.superluminalrx.com/about/) 2. [superluminalrx.com](https://www.superluminalrx.com/careers/) 3. [cbinsights.com](https://www.cbinsights.com/company/superluminal-medicines) 4. [job-boards.greenhouse.io](https://job-boards.greenhouse.io/superluminalrx) ## Other roles at Superluminal Medicines, Inc. - [Sr. Scientist, In-Vivo Pharmacology](https://feeny.ai/job/sr-scientist-in-vivo-pharmacology-superluminal-medicines-inc-boston-t0xzfs92rdv8) — Boston, MA - [Research Associate, Discovery Biology](https://feeny.ai/job/research-associate-discovery-biology-superluminal-medicines-inc-boston-e0kb5bkcyks8) — Boston, MA - [Sr. Scientist, Discovery Biology](https://feeny.ai/job/sr-scientist-discovery-biology-superluminal-medicines-inc-boston-16yz8snbevdt) — Boston, MA - [Sr. Scientist / Principal Scientist, Computational Chemistry](https://feeny.ai/job/sr-scientist-principal-scientist-computational-chemistry-superluminal-medicines-amgvtc3fygv1) — Boston, MA