---
title: 'Scientist/Senior Scientist - Hemodynamic Biology at e184'
canonical: 'https://feeny.ai/job/scientist-senior-scientist-hemodynamic-biology-e184-portland-9fbgt0xwcn1a'
type: 'job'
last_seen: '2026-11-08'
---

# Scientist/Senior Scientist - Hemodynamic Biology at e184

- **Company:** e184
- **Location:** Portland, OR
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-11-02
- **Last confirmed live:** 2026-11-08
- **Apply:** https://jobs.lever.co/e184/a01944fa-1f54-47b3-a3c3-2fcab0173ecb

## Job description

## About us

e184 is a biotechnology research company dedicated to overcoming the limits of human biology. One of our programs in reproductive technologies develops ectogenesis - the ability to support human development outside the body - to expand reproductive freedom and redefine what is possible in medicine. Our mission is to remove the biological constraints that limit who can safely carry a pregnancy, enabling new pathways to parenthood for individuals facing medical risk, infertility, or physiological barriers to gestation. We operate at the intersection of biology, engineering, and computational science, building integrated platforms that combine advanced tissue models, adaptive culture systems, and automated experimental workflows to understand and recreate the conditions required for healthy human gestation beyond the uterus.

## Role overview

As a Scientist/Senior Scientist at e184, you will define the in vivo blood flow properties our engineered perfusion systems are ultimately built to reproduce, and characterize how the immune system and plasma function within living tissue under those flow conditions. Your work identifies the physiological properties, from vascular resistance and flow patterns to immune-cell trafficking and plasma-protein behavior in tissue, that translates real biology into design targets for the engineering teams. This is a bench-science-driven role for someone who wants to define what "normal" looks like in living tissue before it becomes an engineering specification.

## What you'll do

- Characterize in vivo blood flow: Define flow, pressure, resistance, and shear properties across relevant tissues and gestational stages using in vivo reference data, establishing the physiological targets engineered perfusion systems must reproduce.

- Study immune function within tissue: Characterize resident and trafficking immune cell populations, cytokine signaling, and immune-tolerance mechanisms as they operate within living tissue under normal blood flow conditions.

- Characterize plasma function in tissue: Define how plasma composition behaves and changes as it interacts with tissue in vivo, including oncotic and osmotic effects, protein binding, and delivery of tissue-relevant factors.

- Translate in vivo findings into design targets: Convert physiological characterization into quantitative benchmarks that inform perfusate composition, flow/pressure setpoints, and monitoring requirements for engineered systems.

- Collaborate cross-functionally: Work closely with the engineering team to ensure engineered systems are validated against in vivo physiology.

- Contribute to in vivo reference studies: Support characterization of in vivo reference animal models, generating the datasets other milestones benchmark engineered platforms against.

Core requirements

- PhD in physiology, immunology, hematology, vascular biology, or a related field, with 7+ years of relevant research experience

- Strong understanding of in vivo blood flow dynamics and vascular physiology

- Strong background in immunology, particularly immune cell function and signaling within tissue

- Deep knowledge of plasma composition and its physiological behavior in tissue

- Experience designing and executing in vivo or ex vivo physiological characterization studies

- Strong data analysis and quantitative benchmarking skills

- Strong collaboration and communication skills in interdisciplinary environments

- Comfort working in a fast-paced, iterative startup environment

You'll stand out with

- Experience with placental blood flow and uteroplacental circulation

- Experience in reproductive immunology, particularly maternal-fetal immune interactions

- Experience with in vivo imaging or monitoring of blood flow (e.g., contrast-enhanced ultrasound, Doppler, microcirculatory imaging)

- Experience with comparative physiology across species (rodent, nonhuman primate, human)

- Prior experience translating in vivo physiological data into engineering specifications

Why e184?

- Unrivaled impact: Your work directly enables technology that transforms human fertility and reproductive medicine.

- Full-spectrum growth: Gain exposure to the entire lifecycle of discovery. From screening to mechanistic validation.

- Best of both worlds: Experience the creative chaos of an early-stage startup with the stability of a well-capitalized company.

- Elite collaboration: Work alongside a world-class team who are as driven as you are.

The perks

- Competitive salary + equity participation is considered

- State-of-the-art facility in Portland metro area

- Comprehensive Medical, Dental, Vision, and 401(k) with company match

- 20 days PTO + 11 paid holidays

## About e184

## Company Overview
- **One-liner**: e184 is a biotechnology and neurotechnology research company working to overcome the limits of human biology, focusing on reproductive technologies (ectogenesis, in vitro gametogenesis) and non-implantable brain-computer interfaces.
- **Entity Type**: Private (Funding not publicly disclosed)
- **Headquarters**: Portland, Oregon, United States (with additional offices in the Cayman Islands and a BCI Lab in the United Kingdom)
- **Founded**: 2023
- **Founders**: Not publicly named (key executives include Aleksei Mikhalchenko, Chief Scientific Officer; Gavin Morley, CEO of BCI Lab; Pablo Hurtado González, COO)

## Core Business
- **Primary industries**: Biotechnology Research, Neurotechnology
- **Target customers**: B2B (research institutions, medical partners) and direct impact on individuals (future reproductive medicine, human-AI integration)
- **Mission or purpose**: To overcome the limits of human biology – beginning with reproduction and following life’s logic into symbiosis and beyond.

## Products & Services
- **Repro Lab (Ectogenesis & In Vitro Gametogenesis)**: Research and development of technology to support human development outside the body (ectogenesis) and create functional gametes from other cell types (IVG). Aimed at expanding reproductive freedom and enabling new pathways to parenthood. [e184.com/repro](https://www.e184.com/repro)
- **BCI Lab (Brain-Computer Interface)**: Development of a non-implantable brain-computer interface based on advanced sensors, intended to enable fluid human-AI collaboration and extend cognition, bandwidth, and memory. [e184.com/bci](https://e184.com/bci)

## Market Standing
- **Valuation/Market Cap**: Not disclosed
- **Key Metric**: 14 employees (as of 2026), with +100% year-over-year headcount growth
- **Notable Investors/Partners**: Not publicly listed (the company describes itself as “well-capitalized” in job postings)
- **Growth Signals**: Rapid team expansion (doubled headcount in the last year); active hiring across multiple scientific and engineering roles; distributed workforce across 6 countries (US, UK, Denmark, Cyprus, Mexico, Germany)

## Competitive Advantages
- **Pioneering focus**: Combines two frontier fields – ectogenesis/IVG and non-implantable BCIs – under one company, creating unique cross-disciplinary synergies.
- **Non-implantable BCI approach**: Targets true brain–AI integration without invasive surgery, potentially unlocking broader adoption and scalability.
- **Mission-driven science**: Tackles fundamental biological constraints (reproduction, cognition) that few startups address, attracting top talent from institutions like Insitro, Institut Pasteur, and Washington State University.

## Strategic Focus
- **Reproductive technology**: Advancing ectogenesis and in vitro gametogenesis to remove biological barriers to parenthood.
- **Neurotechnology**: Building scalable, non-implantable brain-computer interfaces for fluid human-AI collaboration.
- **Talent acquisition**: Aggressively hiring scientists, engineers, and industry professionals in both Portland (Repro Lab) and the UK (BCI Lab).

## Why Work Here
- **Unrivaled impact**: Directly contribute to technology that could transform human fertility and human-AI interaction.
- **Full-spectrum growth**: Exposure to the entire lifecycle of discovery – from screening to mechanistic validation.
- **Elite collaboration**: Work alongside a world-class, highly driven team in a fast-paced startup environment.
- **Benefits**: Competitive salary + equity; state-of-the-art facilities in Portland metro area; comprehensive Medical, Dental, Vision, and 401(k) with company match; 20 days PTO + 11 paid holidays. [jobs.lever.co/e184](https://jobs.lever.co/e184/3fbf4093-2621-4d4d-badf-7cf64ef7d70a)
- **Work policy**: Likely on-site for lab roles (Portland for Repro Lab, UK for BCI Lab); remote/hybrid not specified.

## Sources
1. [linkedin.com/company/e184](https://linkedin.com/company/e184)
2. [e184.com](https://www.e184.com)
3. [e184.com/repro](https://www.e184.com/repro)
4. [e184.com/bci](https://e184.com/bci)
5. [jobs.lever.co/e184](https://jobs.lever.co/e184/3fbf4093-2621-4d4d-badf-7cf64ef7d70a)

## Other roles at e184

- [Biosensor Integration Engineer](https://feeny.ai/job/biosensor-integration-engineer-e184-portland-35e18f1dery2) — Portland, OR
- [Senior Scientist - Tissue Engineer](https://feeny.ai/job/senior-scientist-tissue-engineer-e184-portland-101hrqb3gywz) — Portland, OR