--- title: 'Scientist / Sr. Scientist In Vivo Translational Sciences at Altos Labs' canonical: 'https://feeny.ai/job/scientist-sr-scientist-in-vivo-translational-sciences-altos-labs-san-francisco-89z998pb5r1a' type: 'job' last_seen: '2026-10-15' --- # Scientist / Sr. Scientist In Vivo Translational Sciences at Altos Labs - **Company:** Altos Labs - **Location:** San Francisco Bay Area, CA - **Posted:** 2026-09-11 - **Last confirmed live:** 2026-10-15 - **Apply:** https://job-boards.greenhouse.io/altoslabs/jobs/6186161004 ## Job description ## Our Mission Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life. For more information, see our website at [altoslabs.com.](https://altoslabs.com/) Our Value Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission. Diversity at Altos Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list.  At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment. ## What You Will Contribute To Altos An exciting opportunity is available for a Scientist to join the In Vivo Translational Sciences team within Drug Discovery and Development Sciences (3DS) at Altos Labs. We are seeking a dedicated and highly skilled Scientist for our In Vivo Pharmacology Operations. In this role you will be responsible for the full lifecycle of in vivo pharmacology studies — from design and protocol development through execution, analysis, and interpretation — to support the progression of our therapeutic programs. This role demands a solid understanding of in vivo research methodologies and the ability to operate in a complex, fast-moving research environment. ## Responsibilities - Lead the full lifecycle of in vivo pharmacology studies across multiple projects — providing in vivo pharmacology and physiology expertise from study design and model selection through dosing and in-life monitoring, tissue collection and processing, data analysis, interpretation, and reporting of results to program teams - Contribute to selection of pharmacodynamic and target-engagement readouts - Contribute to building translational strategy by leveraging in vivo research for target validation and candidate progression - Develop, characterize, and implement new animal models; including models of fibrosis and other age-related pathologies - Evaluate and implement new technologies, platforms, and best practices for in vivo research to enhance study efficiency and quality - Execute studies in both mice and rats, including conducting survival surgeries to establish rodent models using aseptic technique - Occasionally execute downstream ex vivo analyses - Maintain detailed documentation of all studies in the electronic lab notebook to ensure data integrity and traceability - Collaborate with cross-functional partners across discovery biology, pharmacology and assay sciences, DMPK, and technology development to advance therapeutic programs - Ensure all in vivo work meets IACUC-approved protocols and uphold the highest ethical standards in study conduct - Contribute to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion ## Who You Are - Ph.D. in biological sciences with a minimum of 3-5 years (Scientist) and 6+ years (Sr. Scientist) of industry experience in a drug discovery and development setting - Extensive expertise with all aspects of in vivo rodent research (various dosing routes, anesthesia, surgical procedures, necropsy, tissue processing, etc.) in both mice and rats - Strong commitment to animal welfare and a 3Rs-centered approach to experimental design - Excellent communication skills for effective collaboration with internal teams and external CRO partners - Exceptional organizational skills, strong attention to detail, and the ability to work independently and collaboratively in a dynamic environment - Demonstrate creative thinking and a proactive, solution-oriented mindset; able to design, troubleshoot, and refine complex in vivo studies with resourcefulness and innovation - High-level problem-solving ability with strong analytical thinking and the capacity to make practical, data-driven decisions - Hands-on experience with molecular and cell biology techniques (RNA/DNA extraction, PCR, Western blot, ELISA, and small molecule/biologic assays) - Willingness and ability to work in a lab/vivarium environment for the majority of working hours, including supporting weekend study needs ## Preferred Qualifications - Experience working across diverse therapeutic modalities, including small molecules, biotherapeutics, nucleic acid therapeutics, and gene therapy is highly desirable - Experience analyzing age-related diseases/deficits in animal models, including fibrosis, inflammation, metabolic disorders or neurodegeneration The salary range for Redwood City, CA - Scientist II, In Vivo Pharmacology: $148,400 - $190,300 - Senior Scientist I, In Vivo Pharmacology $171,400 - $219,700 Exact compensation may vary based on skills, experience, and location. ## #LI-NN1 For UK applicants, before submitting your application: - Please click here to read the Altos Labs EU and UK Applicant Privacy Notice ([bit.ly/eu_uk_privacy_notice](https://bit.ly/eu_uk_privacy_notice)) - This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment. ## Equal Opportunity Employment We value collaboration and scientific excellence. We believe that a culture of belonging are foundational to scientific innovation and inquiry. At Altos Labs, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining an inclusive environment. Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training. Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging. Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/ ## About Altos Labs ## Company Overview - **One-liner**: Altos Labs is a biotechnology company pioneering cellular rejuvenation programming to reverse disease, injury, and disabilities by restoring cell health and resilience. - **Entity Type**: Private (believed to be well-funded by high-profile investors including Jeff Bezos and Yuri Milner; no public funding rounds listed) - **Headquarters**: San Francisco Bay Area, CA, USA (also major sites in San Diego, CA and Cambridge, UK) - **Founded**: 2021 (publicly launched in January 2022) - **Founders**: Hal Barron (CEO), Hans Bishop (President), Rick Klausner (Chief Scientific Advisor) ## Core Business - **Primary industry**: Biotechnology / Longevity & Cell Rejuvenation / Drug Discovery - **Target customers**: B2B/Institutional (partners, academic collaborators); ultimate end-users are patients with age-related diseases - **Mission statement**: “To restore cell health and resilience through cell rejuvenation to reverse disease, injury and the disabilities that can occur throughout life.” ## Products & Services Currently in the research and preclinical/early clinical stage. No marketed products yet. Major initiatives include: - **[Cell Rejuvenation Programming Platform]**: Proprietary technology based on partial cellular reprogramming (building on Yamanaka factors and Belmonte lab discoveries) to reset epigenetic age and restore cell function. - **[Institute of Computation]**: Developing multi-scale generative AI models to decode the “language of cell health” and accelerate discovery of rejuvenation-based therapies. - **[Institute of Medicine]**: Translational arm focused on converting fundamental biology into potential breakthrough medicines for age-related diseases. - **[Discovery Engine]**: Integrated platform combining experimental biology, high-quality internal data generation, and computational modeling to identify novel targets and therapies. ## Market Standing - **Valuation/Market Cap**: Not publicly disclosed; widely reported to have raised over **$3 billion** in initial financing (one of the largest biotech startup financings ever). Investors include Jeff Bezos, Yuri Milner, and others. - **Key Metric**: **$3+ billion total funding** (reported launch round) - **Notable Investors/Partners**: Jeff Bezos (via Bezos Expeditions), Yuri Milner (via DST Global), and other undisclosed high-net-worth individuals; partnerships with leading academic institutions including the Salk Institute and Cambridge University. - **Growth Signals**: Rapidly scaling headcount (26 open roles listed on Greenhouse as of mid-2026); expansion of computational and AI teams; launched Institute of Computation; appointed Joan Mannick (M.D.) as Chief Medical Officer in 2025 to lead early clinical development. ## Competitive Advantages - **Massive capital base**: Over $3 billion in funding provides long runway for high-risk, long-horizon science. - **World-class scientific leadership**: CEO Hal Barron (ex-GSK, ex-Roche), President Hans Bishop (ex-Juno Therapeutics), Chief Scientific Advisor Rick Klausner, and founding scientist Juan Carlos Izpisua Belmonte (pioneer of partial reprogramming). - **“Academic freedom meets industry focus” model**: Combines the freedom of academic inquiry with the discipline and resources of a biotech company. - **AI-first approach**: Dedicated Institute of Computation with a focus on generative AI and foundational models for biology, differentiating from traditional drug discovery. - **Multi-site global footprint**: Operations spanning US (Bay Area, San Diego) and UK (Cambridge) attract top talent from both sides of the Atlantic. ## Strategic Focus - **Near-term**: Advancing first therapeutic programs into clinical trials; building out the Institute of Computation and AI models; scaling drug discovery and development capabilities. - **Long-term**: Transform medicine by developing therapies that address the root cause of disease—cellular aging—rather than just symptoms. ## Why Work Here - **Mission-driven culture**: Focus on a single, ambitious goal—reversing disease through cell rejuvenation—unites the organization. - **Unique work model**: Blends academic freedom (pursue deep questions, publish, collaborate openly) with industry urgency (focus on medicines, milestones, patient impact). - **Computational focus**: Heavy investment in AI/ML (machine learning scientists, AI engineers, computational biology) makes it appealing for those interested in the intersection of tech and biology. - **Work environment**: Collaborative, interdisciplinary, and global; values diverse perspectives. Described as “a unique and inspiring place to work” with “many ways to contribute to our mission.” - **Currently hiring across multiple disciplines**: Discovery Science, Drug Development, Computation, Technology, and Operations—with roles in San Francisco Bay Area, San Diego, and Cambridge, UK. - **Perks/culture highlights**: Not explicitly detailed on careers page, but the emphasis on “freedom to collaborate broadly” and “big questions” suggests a high-autonomy, high-trust environment. ### Company Website & Careers 1. [altoslabs.com](https://www.altoslabs.com/) – Official company site (overview, science, about, careers) 2. [altoslabs.com/careers](https://www.altoslabs.com/careers) – Careers page (mission, culture, job listings) 3. [altoslabs.com/about](https://www.altoslabs.com/about) – About page (leadership, institutes, model) 4. [altoslabs.com/science](https://www.altoslabs.com/science) – Science page (founding science, partial reprogramming) ### Job Board 5. [job-boards.greenhouse.io/altoslabs](http://job-boards.greenhouse.io/altoslabs) – Greenhouse job board (26 open positions as of mid-2026) ## Other roles at Altos Labs - [Manager / Senior Manager Genomics Hub](https://feeny.ai/job/manager-senior-manager-genomics-hub-altos-labs-cambridge-2c83teqhdrg9) — Cambridge, MA - [Senior Knowledge Engineer, Ontology and Data Standards (Contract)](https://feeny.ai/job/senior-knowledge-engineer-ontology-and-data-standards-contract-altos-labs-san-0gj7kggw8sq9) — San Francisco Bay Area, CA - [Senior Patent Counsel / Director, Intellectual Property](https://feeny.ai/job/senior-patent-counsel-director-intellectual-property-altos-labs-san-diego-rqa72w59efpg) — San Diego, CA - [Deputy General Counsel and Vice President, Intellectual Property](https://feeny.ai/job/deputy-general-counsel-and-vice-president-intellectual-property-altos-labs-san-rfncypwagg9c) — San Francisco Bay Area, CA - [Director / Senior Director, Lab-in-the-Loop](https://feeny.ai/job/director-senior-director-lab-in-the-loop-altos-labs-san-francisco-bay-area-x0r6dn63de1j) — San Francisco Bay Area, CA / San Diego, CA - [Senior Manager/Manager, CRO and KOL Alliances (Contract to Hire)](https://feeny.ai/job/senior-manager-manager-cro-and-kol-alliances-contract-to-hire-altos-labs-san-vw71whqxekvc) — San Diego, CA - [Scientist / Senior Scientist, Membrane Biochemistry](https://feeny.ai/job/scientist-senior-scientist-membrane-biochemistry-altos-labs-san-francisco-bay-2as6grjx00j9) — San Francisco Bay Area, CA - [Scientist, Neurodegeneration](https://feeny.ai/job/scientist-neurodegeneration-altos-labs-san-francisco-bay-area-ptan9vfe9dfh) — San Francisco Bay Area, CA - [Senior Research Associate, Drug Discovery](https://feeny.ai/job/senior-research-associate-drug-discovery-altos-labs-san-francisco-bay-area-es0k39mddn6n) — San Francisco Bay Area, CA - [Director / Senior Director, Machine Learning for Biology](https://feeny.ai/job/director-senior-director-machine-learning-for-biology-altos-labs-san-diego-tav9vfz1h2qf) — San Diego, CA / San Francisco Bay Area, CA