---
title: 'Senior Bioinformatics Engineer at Sequencing'
canonical: 'https://feeny.ai/job/senior-bioinformatics-engineer-sequencing-united-states-y7fmfm7phzkq'
type: 'job'
last_seen: '2026-09-08'
---

# Senior Bioinformatics Engineer at Sequencing

- **Company:** Sequencing
- **Location:** United States
- **Employment:** full-time
- **Work type:** remote
- **Posted:** 2026-07-30
- **Last confirmed live:** 2026-09-08
- **Apply:** https://jobs.gem.com/sequencing/am9icG9zdDp0whx8HhM8IXPas6js-2RG

## Job description

The Position

Sequencing.com is hiring a Senior Bioinformatics Engineer to develop cutting edge genomic analysis tools and infrastructure for the Bioinformatics team. You build the data analysis and interpretation that helps users uncover meaningful insights about their health, wellness, and ancestry from their DNA. This role requires expertise in cloud technologies, large scale genomic data processing, and software development. Your work helps power the future of personal genomics.

The Impact

- Design, build, and maintain scalable pipelines for processing and analyzing clinical grade 30x whole genome data.
- Support a wide range of genomic data types at consumer scale.
- Optimize performance, reliability, and cost of data processing pipelines across AWS and hybrid environments.
- Keep throughput high and latency predictable for end users.
- Develop production quality services and tools using Python, C#, SQL, and AWS, including Lambda, Glue, Batch, S3, and RDS.
- Power Sequencing's DNA apps and reports with the services and tools you build.
- Collaborate across product, science, engineering, and UX teams to translate scientific findings into clear, consumer friendly genetic insights that are easy to navigate.
- Establish and adhere to best practices for software engineering, data versioning, testing, observability, and documentation across bioinformatics workflows.
- Debug complex data and infrastructure issues with a systematic approach.
- Operate and improve production systems where correctness and reliability are critical.
- Leverage AI tools to increase productivity, code quality, and testing depth.
- Deliver high quality, validated output.

## Qualifications

- 5+ years of experience in bioinformatics, computational biology, computer science, or a related field.
- Strong hands on experience working with real world genomic datasets and file formats such as VCF, BAM, and FASTQ.
- Solid understanding of genomic databases, standards, and annotation resources.
- Proficient in Python, SQL, and C#, with a track record of writing clean, maintainable code.
- Designed and implemented bioinformatics pipelines and data processing systems in production.
- Built scalable, reliable systems on cloud platforms such as AWS, including the use of managed services.
- Familiar with containerization and orchestration technologies such as Docker and Kubernetes.
- Excellent problem solving skills and exceptional attention to detail.
- Fluent in English, both written and verbal, with clear communication across technical and non technical stakeholders.

## About Sequencing

## Company Overview
- **One-liner**: Sequencing is a genomics platform that provides clinical-grade whole genome sequencing, free lifetime DNA data storage, and AI-powered interpretation to deliver personalized health, wellness, and ancestry insights.
- **Entity Type**: Private (seed-stage; $5M total funding)
- **Headquarters**: Pasadena, California, United States
- **Founded**: 2017
- **Founders**: Brandon Colby, MD

## Core Business
- **Primary industry**: Biotechnology Research / Digital Health (genomics, bioinformatics, AI-driven health)
- **Target customers**: B2C (individuals seeking DNA insights), B2B (healthcare professionals, healthtech companies)
- **Mission**: To help everyone outsmart their genes by making genomic data accessible, actionable, and transformative for humanity.

## Products & Services
- **Clinical-Grade Whole Genome Sequencing (WGS)**: 30x coverage WGS service delivered via at-home DNA kit or direct lab partnership.
- **Free Lifetime DNA Data Storage**: Unlimited, secure storage of raw genetic data.
- **App & Report Marketplace**: Ecosystem of third-party and proprietary apps/reports for health, wellness, ancestry, and longevity.
- **AI-Powered Interpretation**: Proprietary algorithms and AI combine bioinformatics with machine learning to generate dynamic, actionable insights.
- **Personalized Health Reports**: Ongoing updates covering disease predisposition, medication response, carrier status, and wellness optimization.

## Market Standing
- **Valuation**: Not publicly disclosed
- **Key Metric**: Annual Revenue ~$8M (LinkedIn estimate); Total Funding $5M (seed rounds)
- **Notable Investors/Partners**: Lerer Hippeau (led $5M seed round in November 2022), plus additional undisclosed investors in subsequent rounds.
- **Growth Signals**: Claims to be the world’s largest provider of clinical-grade WGS by volume; global headcount of ~29 employees distributed across 5 countries; fully remote team; expanding AI and bioinformatics capabilities; hiring for senior roles across engineering, security, marketing, and product.

## Competitive Advantages
- **Scale & Data**: Largest base of clinical-grade whole genomes sequenced, providing a unique foundation for AI training and genomic intelligence.
- **Privacy & Storage**: Free, unlimited DNA data storage with strong emphasis on privacy (HIPAA compliance).
- **Marketplace Model**: Open ecosystem of DNA apps/reports that continuously add value for users.
- **AI-Native Platform**: Combines deterministic bioinformatics with AI reasoning to ensure scientifically accurate, explainable insights.
- **Clinical-Grade Quality**: 30x WGS ensures highest accuracy for actionable health decisions.

## Strategic Focus
- Building the lifelong home for every human genome – a trusted platform for storage, interpretation, and continuous value.
- Expanding the AI-native genomic intelligence layer to support prevention, longevity, and personalized care.
- Growing the developer and partner ecosystem around the Sequencing platform.
- Scaling B2B partnerships with healthcare providers and healthtech companies.
- Preparing for regulatory certifications (SOC 2, ISO 27001) to deepen enterprise trust.

## Why Work Here
- **Culture**: Fully remote, global team of doctors, scientists, engineers, and AI researchers with a mission-driven focus on genomics and health.
- **Work Environment**: Remote-first with offices in Pasadena, Los Angeles, and Sioux Falls; flexible for global time zones.
- **Perks & Engineering Culture**: Opportunity to work at the intersection of genomics, cloud infrastructure (AWS), and AI; emphasis on data privacy, security, and scientific rigor; employee rating 4.0/5.0 on Built In (compensation 4.0, culture 3.1).
- **Growth**: High-impact roles across bioinformatics engineering, AI/ML, security, and product management in a fast-growing startup.

## Sources
1. [sequencing.com](https://sequencing.com/about)
2. [builtin.com](https://builtin.com/company/sequencing-com)
3. [linkedin.com](https://www.linkedin.com/company/sequencing-com)
4. [sequencing.com](https://sequencing.com/knowledge-center/faqs/who-is-sequencing)
5. [builtin.com](https://builtin.com/company/sequencing-com/jobs)

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