---
title: 'Senior Clinical Research Associate at Pedestal Health'
canonical: 'https://feeny.ai/job/senior-clinical-research-associate-pedestal-health-research-triangle-park-mms5e1bjft8k'
type: 'job'
last_seen: '2026-09-14'
---

# Senior Clinical Research Associate at Pedestal Health

- **Company:** Pedestal Health
- **Location:** Research Triangle Park, NC
- **Posted:** 2026-08-19
- **Last confirmed live:** 2026-09-14
- **Apply:** https://job-boards.greenhouse.io/pedestalhealth/jobs/5395374008

## Job description

## About Pedestal Health

Pedestal Health (formerly Target RWE) combines deep health system partnerships, longitudinal data curation at scale, and modern study design to build continuous, high-quality evidence for life sciences organizations. The company partners with pharmaceutical and biotech companies, providers and payers to generate rigorous, multimodal evidence that supports clinical, regulatory and strategic decision-making across the full lifecycle of care. Pedestal Health is committed to advancing medical decision making to improve outcomes for patients. Pedestal Health is a Highlander Health company. Learn more at [pedestalhealth.com](http://pedestalhealth.com).

## The Role

Pedestal Health is seeking a Senior Clinical Research Associate to conduct site management and data monitoring of assigned clinical sites, ensuring all activities are conducted in accordance with applicable Good Clinical Practices (GCP) and Standard Operating Procedures (SOPs). In addition to core monitoring responsibilities, the Senior CRA serves as a mentor to other CRAs and as a technical subject matter expert within the organization.

## What You’ll Do

- Conduct remote site selection visits (PSVs) to evaluate whether facilities and staff are adequate for conducting the study.
- Conduct remote site initiation visits (SIVs) to ensure sites and study staff are adequately trained and prepared to conduct the study.
- Verify that investigator(s) and study personnel are conducting the study in accordance with the protocol, GCP, and applicable regulatory requirements to protect the rights and ensure the ethical treatment of human subjects.
- Perform monitoring activities per the monitoring plan, including verification of source documents, informed consent review, site communications, and follow-up on data anomalies.
- Review the accuracy and completeness of site records, including essential documents, query resolution, and other study documentation.
- Ensure complete and accurate reporting and documentation of all monitoring activities.
- Assist with site start-up activities, including developing PSV/SIV presentation materials and supporting the Regulatory and Site Contracting teams in the collection and review of regulatory documents.
- Review and contribute to study plans and procedures, including the Monitoring Plan, Trial Management Plan, and Risk Plan.
- Travel to conduct on-site visits as needed. This position assumes the bulk of monitoring will be conducted remotely, but travel up to 25% may be required.
- Perform other duties as assigned.

Senior-Level Responsibilities

- Act as a mentor and role model for other Clinical Research Associates.
- Act as a technical subject matter expert and point of contact for management and other departments.

## What You’ll Bring

- Bachelor's degree preferred, preferably in science or a related field, with 5+ years of CRA or advanced clinical data experience.
- Substantial site management experience, or equivalent experience in clinical research and/or clinical studies.
- Ability to handle complex problems regularly, with a wide latitude for independent judgment.
- Solid understanding of clinical research and clinical studies methodology and terminology.
- Excellent written and verbal communication skills.
- Excellent Microsoft Office skills, along with computer data acquisition and report-writing ability.
- Ability to interact effectively with all levels of internal and external contacts.
- Ability to independently set and manage multiple priorities and evaluate unpredictable scenarios to achieve project timelines and deliverables.
- An equivalent combination of education and experience will be considered.
- Ability to work in a hybrid environment based in Research Triangle Park, NC (3 days in office, 2 days remote). This position assumes the bulk of monitoring will be conducted remotely, but travel up to 25% may be required.

## Nice to Have

- Certified Clinical Research Associate (CCRA) certification.
- Real-world evidence or Phase IV experience.
- Experience managing studies in REDCap Cloud highly desirable.

## What We Offer You

- Hybrid work arrangement, with regular onsite collaboration at a Pedestal Health office
- Comprehensive health, dental, and vision coverage
- 401(k) with company match
- Generous PTO and paid parental leave

If you are ready to be part of a team where your work truly matters—where your expertise is valued, your growth is supported, and your contributions help shape the future of healthcare—Pedestal Health is the place for you. We’re building something meaningful together, and we’d love for you to be a part of it.

Pedestal Health is an equal opportunity employer and seeks candidates from diverse backgrounds and abilities.

## About Pedestal Health

## Company Overview
- **One-liner**: Pedestal Health is an integrated evidence generation partner for life sciences organizations, building continuous, longitudinal patient cohorts to support drug development, regulatory decisions, and clinical care.
- **Entity Type**: Private (Part of Highlander Health, a venture-backed company co-founded by Amy Abernethy and Brad Hirsch)
- **Headquarters**: Durham, North Carolina, USA
- **Founded**: The company emerged from the rebranding of Target RWE and NoviSci, announced in May 2026. Target RWE was founded earlier; the current entity is the result of that merger.
- **Founders**: Co-CEOs: Amy Abernethy, MD, PhD, and Brad Hirsch, MD

## Core Business
- **Primary industry/industries**: Healthcare Technology, Real-World Evidence (RWE), Clinical Research, Life Sciences Data & Analytics
- **Target customers**: Pharmaceutical and biotech companies, health systems, payers, and regulatory bodies (FDA/EMA).
- **Mission or purpose statement**: To build a modern evidence-generation engine that reduces treatment access time by 50% through continuous evidence and personalized care, moving from episodic, start-from-scratch clinical studies to an infrastructure that compounds over time.

## Products & Services
- **Longitudinal Real-World Data Cohorts**: Deeply phenotyped, disease-specific patient datasets (e.g., hepatology, dermatology, gastroenterology) built directly from clinical practice, continuously queried for safety, effectiveness, and regulatory studies.
- **Regulatory-Grade Evidence Generation**: Full-service design and execution of externally controlled trials, prospective interventional studies, registries, and traditional real-world evidence studies for submission to FDA/EMA/HTA bodies.
- **Headwater Science (Sister Company)**: A methodological and analytical engine offering deep expertise in causal inference, comparative effectiveness, healthcare utilization, and regulatory-grade analytical software. This is a separate but closely integrated entity within Highlander Health.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed.
- **Key Metric**: Formed from the merger of two established companies (Target RWE and NoviSci) with strong existing revenue and partnerships; backed by Highlander Health, which is focused on evidence generation innovation.
- **Notable Investors/Partners**: Highlander Health (the lead investor and parent company). Key health system partnerships are highlighted (e.g., University of North Carolina).
- **Growth Signals**: Rebranding and strategic merger in May 2026 signals significant capital and strategic ambition. The company is actively hiring across multiple roles (engineering, data science, delivery, finance). Leadership includes former FDA Deputy Commissioner (Amy Abernethy) and founder of a successful clinical trial technology company (Brad Hirsch).

## Competitive Advantages
- **Continuous Evidence Infrastructure**: Unlike traditional CROs or data providers, Pedestal builds **continuous** cohorts that compound over time, avoiding the "start from scratch" model for every new study.
- **Deep Clinical Domanin Expertise**: Deepest footprint in hepatology, dermatology, and gastroenterology with pre-existing, deeply phenotyped patient populations and long-standing health system relationships.
- **Regulatory & C-Suite Credibility**: Leadership team with unparalleled experience (former FDA Principal Deputy Commissioner, founders of successful healthcare tech companies, top clinical researchers). This translates into regulatory-grade outputs trusted by agencies.
- **Integrated Methodological Engine (Headwater Science)**: Built-in access to world-class causal inference and data science expertise for complex analytical challenges, a significant moat against generalist competitors.
- **Health System Embeddedness**: Data is sourced directly from clinical practice, offering a richer, more longitudinal picture of patient journeys than claims data alone.

## Strategic Focus
- **Current priorities**: Expanding into new therapeutic areas beyond their core hepatology, dermatology, and GI strongholds. Scaling the "continuous evidence system" model across more biopharma partners. Integrating more deeply with health system IT for seamless data flow.
- **Direction for growth**: Becoming the "evidence infrastructure" for the life sciences industry, moving from project-based work to platform-based, recurring partnerships. Focus on solving the most complex, high-stakes regulatory and access questions.

## Why Work Here
- **Culture**: The company emphasizes passion, dedication, and use of patient data to shift the healthcare paradigm. They highlight "diverse and innovative perspectives" as core to their cutting-edge approach.
- **Remote/Hybrid Policy**: **Hybrid work** is explicitly offered as a benefit.
- **Notable Perks & Benefits**:
    - Competitive Health Insurance
    - **Paid Parental Leave**
    - Professional Development Courses
    - Employee Recognition Programs
    - Paid Holidays & Floating Holidays
    - **401(k) with Company Match & Immediate Vesting**
    - Paid Time Off
- **Engineering/Data Science Culture**: At the intersection of clinical research, data science, and regulatory technology. The work directly impacts drug development timelines and patient access. The team includes world-class biostatisticians, epidemiologists, data engineers, and product managers. For those passionate about data for social impact in health, this is a mission-driven, fast-paced environment backed by deep expertise.

## Sources
1. [Pedestal Health Official Website](https://www.pedestalhealth.com/)
2. [About Us / Leadership](https://www.pedestalhealth.com/about/)
3. [Careers Page (Greenhouse)](https://job-boards.greenhouse.io/pedestalhealth)
4. [Pedestal Health Careers / Benefits](https://www.pedestalhealth.com/careers/)
5. [Yahoo Finance: Target RWE and NoviSci Rebrand as Pedestal Health and Headwater Science](https://finance.yahoo.com/sectors/healthcare/articles/target-rwe-novisci-rebrand-pedestal-110000567.html)

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