--- title: 'Senior Clinical Research Scientist at Noctrix Health' canonical: 'https://feeny.ai/job/senior-clinical-research-scientist-noctrix-health-pleasanton-qzcr329xc6kz' type: 'job' last_seen: '2026-10-16' --- # Senior Clinical Research Scientist at Noctrix Health - **Company:** Noctrix Health - **Location:** Pleasanton, CA - **Posted:** 2026-10-14 - **Last confirmed live:** 2026-10-16 - **Apply:** https://job-boards.greenhouse.io/noctrixhealth/jobs/5451829008 ## Job description Noctrix Health is redefining the treatment of chronic neurological disorders with clinically validated therapeutic wearables. Our team of medical device specialists, neuroscientists, and consumer electronics engineers is dedicated to delivering prescription-grade therapy with an outstanding user experience. We have pioneered the world’s first drug-free wearable therapy, clinically proven to alleviate symptoms in adults with drug-resistant Restless Legs Syndrome (RLS). Be part of our mission to transform healthcare, improve lives, and drive meaningful change with Noctrix Health. We are seeking an experienced and hands-on Senior Clinical Research Scientist to lead the strategy and execution of clinical research supporting the development and validation of emerging therapeutic technologies. This role will have direct responsibility for study design and analysis, physiological data collection, algorithm development, external research collaborations, and the communication of scientific findings through grants, publications, and conference presentations. The ideal candidate is a highly collaborative scientist who is equally comfortable developing research strategy and working directly with engineering, clinical affairs, investigators, and research partners to execute studies and solve complex scientific problems. This individual will play a critical role in translating physiological and clinical data into meaningful product insights, clinical evidence, and future research opportunities. This is a full-time, hybrid position based in Pleasanton, CA, with a minimum of three days onsite per week, or more depending on business needs. Travel is expected to be approximately 10%. ## Responsibilities - Design and lead the execution of multiple clinical research studies in parallel - Lead the analysis and interpretation of physiological and clinical data sets - Develop research strategies, study plans, protocols, case report forms, and statistical analysis plans that produce scientifically meaningful and operationally feasible data - Develop proof-of-concept algorithms that generate clinically meaningful insights from physiological data, including IMU, PPG, EMG, and other biosensor signals - Collaborate with embedded systems engineers to develop and refine systems for collecting physiological sensor data - Partner closely with Clinical Affairs, Engineering, Product, Regulatory, and other cross-functional teams to support research and product-development priorities - Write and submit grant reports, white papers, abstracts, manuscripts, and peer-reviewed publications - Present research findings at scientific and medical conferences - Develop and manage partnerships and collaborations with investigators, research sites, subject matter experts, and other external research partners - Provide training, technical guidance, and ongoing support to external research partners - Translate research findings into product specifications, user requirements, clinical strategies, and patent applications - Identify opportunities to expand the clinical research program through feasibility studies, external collaborations, publications, and grant applications - Maintain accurate study documentation and ensure research activities are conducted in accordance with applicable Good Clinical Practice standards, company procedures, and regulatory requirements - Manage multiple research projects, priorities, timelines, and stakeholders within a collaborative and fast-paced environment - Maintain a high level of ownership, accountability, scientific rigor, and hands-on involvement throughout study planning, execution, analysis, and reporting ## Requirements - PhD in neuroscience, biomedical engineering, or a closely related scientific or technical field - 3+ years of experience leading clinical research projects, preferably within the medical device industry - 2+ years of experience with physiological signal analysis and algorithm development - Strong first-author publication and/or grant-writing record demonstrating excellent technical writing ability - Proficiency in Python or advanced proficiency in a comparable programming language with the ability to work effectively in Python - Strong data-analysis skills ranging from interpreting small exploratory data sets to analyzing large and complex data sets - Experience designing research studies and developing protocols, analysis plans, and scientific documentation - Experience managing collaborations with investigators, subject matter experts, research sites, or external research partners - Excellent written communication skills, including the ability to produce clear scientific, technical, and regulatory documentation - Excellent verbal communication and presentation skills, including the ability to communicate complex scientific concepts to technical and nontechnical audiences - Enthusiasm for providing hands-on support throughout the planning and execution of clinical research studies - Ability to manage multiple projects and priorities within a complex and rapidly changing environment - Strong sense of ownership, accountability, organization, and scientific integrity - Ability to travel approximately 10% as business needs require ## Preferred Qualifications - Experience managing NIH-funded clinical trials or contributing to successful grant applications - Working knowledge of Good Clinical Practice standards and applicable CFR requirements for clinical research - Experience supporting research and development within an FDA-regulated medical device product-development environment - Experience with wearable technologies, neuromodulation, sleep medicine, neuroscience, or neurological disorders - Experience analyzing IMU, PPG, EMG, EEG, or other physiological and biosensor data - Experience translating clinical and physiological research findings into product requirements, development priorities, or intellectual property - Experience working within a startup, growth-stage, or rapidly evolving medical device organization ## Compensation - Base pay: $130,000–$150,000 per year - Annual bonus eligibility ## About Noctrix Health ## Company Overview - **One-liner**: Noctrix Health develops clinically validated wearable neuromodulation devices as non-pharmaceutical alternatives for managing chronic neurological disorders, starting with Restless Legs Syndrome (RLS). - **Entity Type**: Private (Acquired by ResMed in May 2026 for $340M) - **Headquarters**: Pleasanton, California, United States - **Founded**: 2018 - **Founders**: Jonathan Charlesworth (CSO), Justin Kelly (SVP, Product), Steve Lien (SVP, Patient Access), Shriram Raghunathan (CEO) ## Core Business - **Primary industry/industries**: Medical Device Manufacturing, Neuromodulation, Wearable Therapeutics, Sleep Health - **Target customers**: B2B (healthcare providers, sleep clinics, DMEs) and B2C (patients with Restless Legs Syndrome) - **Mission or purpose statement**: To innovate the next generation of clinically-validated wearable therapeutics to address the unmet needs of millions of people living with chronic medical conditions. ## Products & Services - **[Nidra® Therapy (TOMAC Therapy)]**: A prescription wearable device that delivers Tonic Motor Activation (TOMAC) therapy to treat Restless Legs Syndrome (RLS). It is a non-pharmaceutical, clinically validated alternative that uses neuromodulation to alleviate symptoms without disrupting sleep. The therapy has received favorable inclusion in the American Academy of Sleep Medicine (AASM) clinical practice guidelines and has dedicated CMS reimbursement codes. ## Market Standing - **Valuation/Market Cap**: Acquired by ResMed for $340 million (announced May 6, 2026). - **Key Metric**: Total funding raised was approximately $57M (per CB Insights) to $107.2M (per LinkedIn), with the most recent round being a Series C - II. Annual revenue is estimated at $2.5M (pre-acquisition). - **Notable Investors/Partners**: ResMed (acquirer), OrbiMed, Treo Ventures, The Blue Venture Fund, Sandbox Industries, Bridge Bank. - **Growth Signals**: Headcount grew 100% YoY to 110 employees. The company secured dedicated CMS reimbursement codes for Nidra therapy. The therapy was included in new AASM clinical practice guidelines for RLS. The company was acquired by ResMed for $340M in May 2026, signaling strong validation and a major growth trajectory. ## Competitive Advantages - **First-to-market with a non-pharmaceutical wearable for RLS**: Nidra therapy is a clinically validated, drug-free alternative for a condition affecting ~7% of adults globally, offering a significant differentiator in a market dominated by pharmaceuticals. - **Strong clinical and regulatory moat**: The therapy has been included in AASM clinical practice guidelines and has dedicated CMS reimbursement codes, creating high barriers to entry for competitors. - **Backed by ResMed**: The $340M acquisition by the global leader in sleep health provides immense resources, distribution channels, and market credibility. ## Strategic Focus - **Post-acquisition scaling**: Following the acquisition by ResMed, the primary focus is on rapidly scaling U.S. commercialization, expanding market access, and integrating Nidra therapy into ResMed's global sleep health portfolio. - **Expanding indications**: While currently focused on RLS, the company's platform technology has potential for treating other chronic neurological disorders. - **Building the commercial engine**: The company is actively hiring across sales, marketing, patient access, and engineering roles to support its growth. ## Why Work Here - **Patient-centered mission**: The company is deeply mission-driven, with a culture that prioritizes improving patient lives. Employees describe a strong sense of purpose in delivering life-changing therapy. - **High-growth environment**: With 100% YoY headcount growth, a recent $340M acquisition, and 50+ open roles, this is a fast-scaling company with significant career advancement opportunities. - **Culture of transparency and problem-solving**: The company emphasizes core values like "embrace the unknown," "build trust through transparency," and "win as a team," fostering a collaborative and innovative environment. - **Remote-friendly**: Many roles are listed as remote, including sales, patient access, and support positions, though some engineering and marketing roles are based in Pleasanton, CA, or Pittsburgh, PA. - **Strong engineering and clinical culture**: The team is a mix of seasoned medical device experts, neuroscientists, and engineers from the consumer electronics world, offering a unique blend of high-tech and life-science work. ## Sources 1. [noctrixhealth.com](https://noctrixhealth.com/) 2. [noctrixhealth.com/careers](https://noctrixhealth.com/careers/) 3. [greenhouse.io](http://job-boards.greenhouse.io/noctrixhealth) 4. [linkedin.com](https://www.linkedin.com/company/noctrix-health) 5. [cbinsights.com](https://www.cbinsights.com/company/noctrix-health) ## Other roles at Noctrix Health - [Director, Supply Chain & Operations](https://feeny.ai/job/director-supply-chain-operations-noctrix-health-pleasanton-qsdt7cqdp57t) — Pleasanton, CA - [Payments Associate](https://feeny.ai/job/payments-associate-noctrix-health-pleasanton-4f0515fff7gc) — Pleasanton, CA - [Territory Sales Manager – Georgia](https://feeny.ai/job/territory-sales-manager-georgia-noctrix-health-remote-bbsvb9hxhtbp) - [Staff Accountant](https://feeny.ai/job/staff-accountant-noctrix-health-pleasanton-anhkzmksr5nk) — Pleasanton, CA - [Manager, Regulatory Affairs](https://feeny.ai/job/manager-regulatory-affairs-noctrix-health-pleasanton-rww4jfgpsbbq) — Pleasanton, CA - [Director, Clinical Affairs](https://feeny.ai/job/director-clinical-affairs-noctrix-health-pleasanton-d2z573r6sg9t) — Pleasanton, CA - [Patient Access Appeals Case Manager](https://feeny.ai/job/patient-access-appeals-case-manager-noctrix-health-remote-zhezztk3yg44) - [Patient Access Case Manager](https://feeny.ai/job/patient-access-case-manager-noctrix-health-remote-ed8qk3d71rek) - [Head of Marketing](https://feeny.ai/job/head-of-marketing-noctrix-health-pleasanton-5etv0s0qq434) — Pleasanton, CA - [Senior Full Stack Software Engineer](https://feeny.ai/job/senior-full-stack-software-engineer-noctrix-health-pittsburgh-kfs3r5jfe8bm) — Pittsburgh, PA