---
title: 'Senior Director, Clinical Development at Triveni Bio'
canonical: 'https://feeny.ai/job/senior-director-clinical-development-triveni-bio-watertown-6zqvzj0pe16q'
type: 'job'
last_seen: '2026-10-17'
---

# Senior Director, Clinical Development at Triveni Bio

- **Company:** Triveni Bio
- **Location:** Watertown, MA
- **Compensation:** $330k–$355k
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-09-15
- **Last confirmed live:** 2026-10-17
- **Apply:** https://jobs.lever.co/trivenibio/83954bd3-73c1-4c02-896c-d53c587ca800

## Job description

## COMPANY INTRODUCTION

Triveni Bio is breaking new ground in the identification of novel disease targets – working at the convergence of human genetics, best-in-class antibody design, and precision medicine.  We are pioneering a Mendelian genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Our lead antibody program (TRIV-509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch – providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. In all the work we do, we adhere to our core values: patient impact, bold and rigorous science, open collaboration, kindness & respect.

## SUMMARY

The Senior Director, Clinical Development will lead the clinical strategy and study execution of our I&I development programs. Working closely with internal and external stakeholders, this individual will drive clinical development plans, provide medical leadership across clinical studies, and contribute to study design, protocol development, safety reviews, data interpretation, regulatory submissions, publications, and presentations. As a key member of the development leadership team, this individual will guide cross-functional activities to achieve program objectives while ensuring compliance with ICH-GCP and applicable regulatory requirements.

## RESPONSIBILITIES:

Clinical Strategy & Leadership Develop and execute a multi-year clinical development strategy for our clinical programs. Lead creation and execution of medical plans across the US, Europe, and other potential jurisdictions. Provide medical leadership and scientific guidance to a cross-functional program team through all phases of clinical development. Evaluate and integrate emerging scientific, clinical, and competitive insights into development strategies. Clinical Trial Design & Execution Drive the development of clinical content including protocols, amendments, investigator brochures, informed consent forms, and clinical study reports Lead Medical Monitoring, or provide oversight and guidance to designated Medical Monitors, across clinical programs; provide medical oversight, review safety data, and ensure adherence to protocol and regulatory standards. Partner with clinical operations to support site selection, investigator training, and issue resolution during study conduct. Safety & Compliance Oversee the assessment and interpretation of safety data, including adverse events, safety signals, and risk mitigation strategies. Oversee pharmacovigilance to ensure timely evaluation and reporting of safety information. Ensure clinical programs follow ICH-GCP, ethical standards, and regional/global regulatory requirements. Regulatory & Scientific Communication Contribute to the preparation and review of regulatory submissions including INDs, CTAs, briefing documents, and NDAs/BLAs. Represent the clinical program in interactions with health authorities such as FDA, EMA, and other global agencies. Develop and review key clinical documents including protocols, investigator brochures (IBs), clinical study reports (CSRs), and publications. Cross-Functional Collaboration Partner cross-functionally with Research and Operations functions Provide medical and scientific expertise for internal decision-making, including business development activities as required Support advisory boards, KOL engagement, and scientific congress activities. External Engagement Build and maintain relationships with investigators, key opinion leaders, and external experts. Stay current on scientific advances, competitive intelligence, and therapeutic area trends to inform program direction.

## EXPERIENCE & QUALIFICATIONS

M.D. required; significant I&I or rare disease clinical development experience strongly preferred Minimum of 8+ years of relevant experience with a demonstrated track record of success in clinical research and drug development within academia, biotechnology, and/or the pharmaceutical industry. Demonstrated experience designing and executing clinical programs across multiple phases and geographic regions. Experience with phase 1/2 clinical studies is required Strong knowledge of GCP, ICH guidelines, global regulatory requirements, and the drug development process. Experience building and leading a team of direct reports and contractors Proven medical and scientific leadership of cross-functional teams, with experience engaging regulatory agencies, investigators, KOLs, and external partners. Excellent analytical, strategic, and communication skills. Experience authoring and reviewing key clinical and regulatory documents and contributing to global regulatory submissions and health authority interactions.

The posted range reflects the current reasonable and good faith estimate of the base salary for this full-time position. Actual compensation will be based on a variety of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location and other organizational needs. This role also offers a competitive target bonus, equity, and a comprehensive benefits package.

We are committed to fair pay practices, and we regularly review our compensation programs to ensure they are competitive, equitable, and aligned with our values. Please note that the advertised pay range is not a guarantee or promise of a specific wage.

Triveni Bio, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Official Triveni Bio applications will always be submitted through Lever, our ATS. Any applications that take you to other platforms could be fraudulent. We do not use text or chat applications to conduct interviews or make job offers. Official Triveni Bio correspondence will always be conducted from email addresses ending in @triveni.bio or @hire.lever.co. Please disregard any other communications that do not originate from these domain names. If you receive any suspicious requests or communications, please verify their authenticity before responding.

## About Triveni Bio

## Company Overview
- **One-liner**: Triveni Bio is a clinical-stage biotechnology company applying a genetics-informed precision medicine approach to develop functional antibodies for immune and inflammatory (I&I) disorders.
- **Entity Type**: Private (Series C; total funding $223.4M)
- **Headquarters**: Watertown, Massachusetts, United States
- **Founded**: Not publicly available (earliest funding round was Series A in 2020)
- **Founders**: Not publicly available (key leadership includes CEO Vishal Patel, CSO Jennifer Dovey [founding employee], CMO Bhaskar Srivastava, COO Nicholas Scarchilli)

## Core Business
- Primary industry: Biotechnology (therapeutics for inflammatory and immune-mediated diseases)
- Target customers: Patients with I&I disorders, physicians, and pharmaceutical partners (B2B + B2C model)
- Mission statement: "Our measure of success is the impact we have on patients."

## Products & Services
- **TRIV-509** – A first-in-class, dual-specific, half-life extended monoclonal antibody that inhibits active kallikreins 5 and 7 (KLK5/7). Currently in Phase 2 clinical trials for moderate-to-severe atopic dermatitis, with potential expansion into eosinophilic esophagitis (EoE) and epidermal differentiation disorders (EDD). (Therapeutic antibody – biologic)
- **TRIV-573** – A second-generation bispecific antibody combining dual inhibition of KLK5/7 with an anti-IL‑13 mechanism. Currently in Phase 1, with plans to initiate a Phase 2 proof-of-concept trial in moderate-to-severe atopic dermatitis in the second half of 2026. (Therapeutic antibody – bispecific)
- **TRIV-920** – A first-in-class monoclonal antibody targeting trypsin 1 and 2 for the treatment of pancreatitis (preclinical stage). (Therapeutic antibody – first-in-class)

## Market Standing
- **Valuation**: Not disclosed
- **Key Metric**: Total funding of $223.4M (3 rounds: Series A $16.4M in 2020, Series A‑2 $92M in 2023, Series B $115M in 2024, and an undisclosed Series C led by Janus Henderson Investors and Ascenta Capital in 2026)
- **Notable Investors/Partners**: Atlas Venture, Cormorant Asset Management, Goldman Sachs Alternatives, Janus Henderson Investors, Ascenta Capital
- **Growth Signals**: 43.6% year-over-year headcount growth (now 47 employees); expanded into new headquarters in Watertown, MA; advanced TRIV‑509 into Phase 2; initiated first human studies for TRIV‑573; raised Series C to broaden clinical studies and drive company growth.

## Competitive Advantages
- **Genetics‑informed target selection**: Uses integrated multi‑omic datasets and “knowledge graphs” to identify disease drivers (e.g., KLK5/7 in atopic dermatitis) and leverage both risk and protective alleles.
- **Advanced antibody engineering**: Developed a single monoclonal antibody that binds both KLK5 and KLK7 with equal potency, overcomes historic targeting challenges, and includes half‑life extension for convenient dosing.
- **First‑in‑class potential**: TRIV‑920 addresses pancreatitis, a condition with no approved therapies, showing preclinical reduction of pancreatic damage markers.

## Strategic Focus
- Advance TRIV‑573 through Phase 2 proof‑of‑concept in atopic dermatitis (2H 2026).
- Expand TRIV‑509 into additional indications (EoE, EDD).
- Continue preclinical development of TRIV‑920 for pancreatitis.
- Scale the organization while maintaining a collaborative, patient‑focused culture.

## Why Work Here
- **Culture**: Described as “bold & rigorous,” collaborative, and kind, with a strong emphasis on patient impact. Employees note that leadership actively listens and creates a safe space for ideas.
- **Location**: On-site in Watertown, MA (newly expanded headquarters) with an additional office in Waltham.
- **Work Environment**: Clinical‑stage biotech with exciting science; opportunity to “make medicines for patients in need alongside colleagues pushing the boundaries of science and medicine.”
- **Perks**: Not explicitly detailed, but the organization values “curious minds” and “drive to turn ideas into impact.”

## Sources
1. [triveni.bio/about](https://triveni.bio/about/)
2. [triveni.bio/pipeline](https://triveni.bio/pipeline/)
3. [triveni.bio/science](https://triveni.bio/science/)
4. [linkedin.com/company/triveni-bio](https://linkedin.com/company/triveni-bio)
5. [jobs.lever.co/trivenibio](https://jobs.lever.co/trivenibio)

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