---
title: 'Senior Director, Commercial Accounting at Immunome, Inc.'
canonical: 'https://feeny.ai/job/senior-director-commercial-accounting-immunome-inc-bothell-b6t8y9rjmfjz'
type: 'job'
last_seen: '2026-10-17'
---

# Senior Director, Commercial Accounting at Immunome, Inc.

- **Company:** Immunome, Inc.
- **Location:** Bothell, WA
- **Compensation:** $250k–$291k
- **Posted:** 2026-10-14
- **Last confirmed live:** 2026-10-17
- **Apply:** https://job-boards.greenhouse.io/immunomeinc/jobs/5451936008

## Job description

Company Overview

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.

Position Overview

We are seeking a Senior Director, Commercial Accounting to lead the establishment and execution of commercial accounting operations as we prepare to launch our first product. This role will be instrumental in building scalable accounting processes and the internal control framework for revenue recognition, inventory and cost of goods sold, third-party logistics (3PL) accounting, and gross-to-net considerations while partnering closely with Commercial, Supply Chain, and Finance leadership.

The ideal candidate brings hands-on experience supporting product launches in biotech or life sciences, thrives in a fast-paced, pre-commercial or early-commercial environment, and can balance technical accounting expertise with cross-functional collaboration.

## Responsibilities

Revenue Recognition & Commercial Accounting

- Own and implement ASC 606 revenue recognition policies, procedures, and control activities for product sales.
- Manage the development of a model and oversee accounting processes for gross-to-net reserves (e.g., chargebacks, rebates, returns, Medicaid/Medicare, and other government and commercial programs, as applicable).
- Oversee accounting for the outsourced order-to-cash process, ensuring accurate billing, revenue cut-off, cash application, and reconciliations.
- Prepare and maintain technical accounting memos, internal control narratives, and process documentation to support internal and external audits.
- Collaborate with FP&A, Commercial, Market Access, Supply Chain, Legal, and IT teams to align accounting, forecasting, and operational execution.
- Provide accounting guidance on new commercial initiatives, pricing strategies, and distribution models in a SOX-controlled environment.
- Lead and develop commercial accounting staff and/or external consultants, as appropriate for company size.
- Prepare SEC reporting, audit committee materials, and internal management reporting related to commercial activities.
- Serve as a primary point of contact for external auditors for commercial accounting functions, including walkthroughs, control testing, and issue remediation.

Inventory & COGS

- Own accounting for worldwide commercial and clinical inventory, including costing, overhead rate planning and application, variances, and inventory cost and quantity roll-forwards.
- Direct the review of monthly manufacturing accruals, partner with cross-functional teams to ensure an accurate and timely financial close, and drive process improvements across the accrual close cycle.
- Establish SOX-compliant controls over inventory valuation, reserves, obsolescence, excess inventory, and physical counts.
- Ensure reconciliation and completeness controls between operational systems, 3PL reports, and the general ledger.
- Provide guidance for ERP and 3PL system implementations, including design, testing, internal controls and audit readiness.

## Qualifications

- Bachelor’s degree in Accounting or Finance; CPA preferred.
- 10+ years of progressive accounting experience, including experience in a public company subject to SOX 404(b), or equivalent, ideally 5+ years of experience in Commercial Accounting.
- Significant experience in biotech, pharmaceutical, or life sciences, with direct exposure to commercial operations.
- Demonstrated expertise in ASC 606 revenue recognition, inventory accounting, and cost of goods sold.
- Hands-on experience working with 3PLs, CMOs, and distribution partners in a controlled environment.
- Strong understanding of SOX internal controls, documentation standards, and audit processes.
- Experience building or enhancing accounting processes in a lean, high-growth public company.

Knowledge and Skills

- Excellent communication and cross-functional collaboration skills.
- Ability to operate at both a strategic and detailed execution level.
- Experience supporting a first commercial product launch in a public company preferred.
- Experience scaling SOX processes post-commercialization preferred.

Washington State Pay Range $250,111—$290,621 USD

E/E/O

Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

E-Verify

Immunome, Inc. is a participant in E-Verify. Please review the following notices: [E-Verify Participation Poster](https://immunome.box.com/s/bopxukipfidxjscs4bjxt75f90bvpppk) | https://immunome.box.com/s/r51g9subw1wqni9xkutbl6up635sjr8e | https://immunome.box.com/s/r3ekbimwh988my9vzl76tnlbg60zvh9u.

## About Immunome, Inc.

## Company Overview
- **One-liner**: Immunome is a clinical-stage oncology company developing first-in-class and best-in-class targeted cancer therapies, with a primary focus on antibody-drug conjugates (ADCs).
- **Entity Type**: Public (Nasdaq: IMNM)
- **Headquarters**: Bothell, Washington, United States
- **Founded**: The company was formed through a merger of Morphimmune and Immunome in October 2023.
- **Founders**: The company is led by Clay Siegall, Ph.D. (Chairman, CEO, and President), who co-founded Seagen. The original Immunome entity was founded earlier, but the current company structure dates to the 2023 merger.

## Core Business
- Primary industry/industries: Biotechnology, Oncology, Drug Discovery & Development
- Target customers: Patients with cancer, healthcare providers, and clinical trial sites. The company is a B2B/B2C entity in the healthcare and life sciences space.
- Mission or purpose statement: "Our mission is to improve outcomes for cancer patients by advancing and expanding a portfolio of first-in-class and best-in-class therapeutic candidates." [immunome.com](https://immunome.com/)

## Products & Services
- **Varegacestat (formerly AL102)**: A late-clinical stage gamma secretase inhibitor for the treatment of desmoid tumors. The company submitted a New Drug Application (NDA) to the U.S. FDA in April 2026. [investors.immunome.com](https://investors.immunome.com/)
- **IM-1021**: A ROR1-targeted antibody-drug conjugate (ADC) currently in a Phase 1 trial.
- **IM-3050**: A FAP-targeted radioligand which received IND clearance in Q1 2025.
- **Preclinical ADC Pipeline (IM-1617, IM-1340, IM-1335)**: ADCs pursuing undisclosed targets with expression in multiple solid tumors. IM-1617 had its first patient dosed in a Phase 1 trial in June 2026. [investors.immunome.com](https://investors.immunome.com/)

## Market Standing
- **Valuation/Market Cap**: Not publicly available in the search results. As a public company, this fluctuates. (Check recent filings for current data).
- **Key Metric**: The company is pre-revenue (clinical-stage) and has raised significant capital. Since the 2023 merger, CEO Clay Siegall has raised $355 million in equity financings. [immunome.com](https://immunome.com/about/)
- **Notable Investors/Partners**: The company is publicly traded. Key leadership previously worked at Seagen (acquired by Pfizer for $43 billion).
- **Growth Signals**: The company is rapidly advancing its pipeline. Key milestones include the NDA submission for varegacestat, first patient dosed for IM-1617, and positive Phase 3 data presented at ASCO 2026. The company currently lists 32 open positions on its careers page, indicating strong hiring momentum. [job-boards.greenhouse.io](http://job-boards.greenhouse.io/immunomeinc)

## Competitive Advantages
- **World-Class Leadership**: The executive team, led by Seagen co-founder Clay Siegall, has deep experience in designing, developing, and commercializing blockbuster ADCs (ADCETRIS, PADCEV, TIVDAK, TUKYSA). [immunome.com](https://immunome.com/about/)
- **Proprietary ADC Platform**: A systematic, data-driven process for optimizing antibodies, linkers, and payloads to create differentiated ADCs. [immunome.com](https://immunome.com/)
- **Near-Term Catalyst**: The NDA submission for varegacestat provides a potential near-term commercial opportunity.
- **Strong Financial Backing**: Raised $355M in equity since the merger, providing a solid runway for pipeline advancement.

## Strategic Focus
- **Advancing the Pipeline**: The primary focus is on executing clinical trials for varegacestat (Phase 3), IM-1021 (Phase 1), and IM-3050 (Phase 1), and advancing preclinical ADCs into the clinic.
- **Regulatory Filing**: Successfully navigating the FDA NDA submission and potential approval for varegacestat.
- **Discovery & Expansion**: Using their ADC discovery platform to generate new candidates and identify and acquire targeted oncology assets to expand the portfolio. [immunome.com](https://immunome.com/about/)

## Why Work Here
- **Mission-Driven**: The work directly impacts the lives of cancer patients, with a stated goal of developing transformative therapies. [immunome.com](https://immunome.com/about/)
- **High-Impact Team**: Opportunity to work with "some of the brightest and most experienced minds in ADC development," including leaders who have brought multiple drugs to market. [immunome.com](https://immunome.com/careers/)
- **Growth Stage**: With 32 open roles, the company is in a rapid growth phase, offering significant career advancement opportunities. [job-boards.greenhouse.io](http://job-boards.greenhouse.io/immunomeinc)
- **Comprehensive Benefits**: Includes 100% company-paid medical premiums for employees, a 401(k) with employer match, paid parental leave, and a week-long winter break. [immunome.com](https://immunome.com/careers/)
- **Location & Culture**: Based in Bothell, WA. The company describes a culture of "innovative, collaborative environment where employees are empowered to do their best work." [immunome.com](https://immunome.com/careers/)

## Sources
1. [Immunome Official Website](https://immunome.com/)
2. [Immunome About Page](https://immunome.com/about/)
3. [Immunome Investor Relations](https://investors.immunome.com/)
4. [Immunome Careers Page](https://immunome.com/careers/)
5. [Immunome Jobs on Greenhouse](http://job-boards.greenhouse.io/immunomeinc)

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