---
title: 'Senior Director, HR Business Partner at Mirum Pharmaceuticals'
canonical: 'https://feeny.ai/job/senior-director-hr-business-partner-mirum-pharmaceuticals-foster-city-4hhwex05d1hc'
type: 'job'
last_seen: '2026-10-14'
---

# Senior Director, HR Business Partner at Mirum Pharmaceuticals

- **Company:** Mirum Pharmaceuticals
- **Location:** Foster City, CA
- **Posted:** 2026-10-14
- **Last confirmed live:** 2026-10-14
- **Apply:** https://job-boards.greenhouse.io/mirumpharmaceuticals/jobs/5265102007

## Job description

## MISSION

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.

## POSITION SUMMARY

The Senior Director, Human Resources will report to the VP, Global Human Resources (HRBP for North America Commercial and Global Talent Development). This role will partner closely with Mirum’s Technical Operations, Quality, and G&A leaders and employees, providing strategic HR guidance and solutions that align with business objectives and are consistent with our company values. The Senior Director will advise on HR initiatives, coach leaders, foster organizational effectiveness, and ensure alignment between people strategies and business growth priorities.

## JOB FUNCTIONS/RESPONSIBILITIES

- Serve as a trusted advisor to senior leaders, translating business strategy into people, organization, and talent priorities that support growth and business performance.
- Partner with leaders to assess organizational effectiveness, design scalable organizational structures, and lead change initiatives that enable business objectives.
- Coach and develop leaders to enhance leadership effectiveness, strengthen team performance, navigate complex employee and organizational issues, and build high-performing teams.
- Lead workforce planning, talent management, succession planning, and leadership development strategies to ensure the organization has the capabilities needed to achieve current and future goals.
- Partner with Talent Acquisition and business leaders to identify capability needs and develop strategies to attract, develop, engage, and retain top talent.
- Use workforce data, people analytics, and business insights to identify trends, assess risks, and influence talent and organizational decisions.
- Facilitate talent reviews, performance management, and development planning processes to drive a culture of accountability, growth, and high performance.
- Partner closely with HR Centers of Excellence and HRBPs globally to deliver integrated, consistent, and scalable people solutions across the organization.
- Lead or contribute to enterprise-wide HR initiatives and programs that enhance employee engagement, organizational effectiveness, and the overall employee experience.
- Manage complex employee relations matters, investigations, and organizational issues with sound judgment, objectivity, and compliance with company policies and employment laws.
- Ensure compliance with applicable employment laws and regulations while proactively identifying and mitigating people-related risks.
- Partner with the VP, Global Human Resources to continue to evolve and strengthen the HR Business Partner function, driving consistency, effectiveness, and strategic impact across the organization.

## QUALIFICATIONS

Education /Experience:

- Bachelor’s degree in human resources or a related field required.
- 12+ years of HR experience, or an equivalent combination of education and experience.

Knowledge, Skills and Abilities:

- Proven ability to serve as a trusted advisor to senior leaders, translating business strategy into people, organization, and talent solutions within the biotechnology or pharmaceutical industry.
- Experience supporting organizations through growth and transformation.
- Strong business acumen with the ability to understand operational, financial, and organizational drivers of business performance and influence decision-making across all levels of the organization.
- Demonstrated expertise in organizational effectiveness, organizational design, workforce planning, and change management, including the ability to diagnose complex organizational challenges and implement practical, scalable solutions.
- Experience coaching and developing leaders and technical professionals to strengthen leadership effectiveness, team performance, and organizational capability.
- Proven success leading talent management processes, including talent reviews, succession planning, leadership development, and employee growth strategies.
- Ability to leverage workforce data and people analytics to identify trends, anticipate risks, and drive evidence-based talent and organizational decisions.
- Strong consulting, facilitation, and relationship-building skills, with the ability to influence and navigate complex organizational dynamics without direct authority.
- Skilled in managing complex employee relations matters, conducting objective investigations, and providing sound, actionable recommendations.
- Excellent written, verbal, and interpersonal communication skills with the ability to influence, educate, and build credibility across diverse audiences.
- Strong knowledge of employment laws, HR practices, and compliance requirements in a multi-state and global environment.
- Demonstrated ability to build, strengthen, and scale HR Business Partner capabilities and practices to deliver strategic value and organizational impact.

The salary range for this position is $270,000 to $290,000 USD. Compensation will be determined based on several factors including, but not limited to; skill set, years of experience, and the employee’s geographic location. Please note that the required compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits unless otherwise provided.

## #LI-HYBRID

Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and to compliance with all Federal, State and Local laws that prohibit employment discrimination on the basis of race, age, national origin, ethnicity, religion, gender, gender identity, pregnancy, marital status, sexual orientation, citizenship, genetic disposition or characteristics, disability, veteran’s status or any other classification protected by applicable State/Federal/Local laws.

Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.

## About Mirum Pharmaceuticals

## Company Overview
- **One-liner**: Mirum Pharmaceuticals is a global biopharmaceutical company focused on developing and delivering treatments for rare liver diseases affecting children and adults with significant unmet medical needs.
- **Entity Type**: Public (NASDAQ: MIRM)
- **Headquarters**: Foster City, California, USA
- **Founded**: 2018
- **Founders**: Not publicly listed as individual founders; the company was established by a leadership team with deep rare disease and biotech experience who identified a deprioritized therapy for Alagille syndrome and moved decisively to advance it.

## Core Business
- **Primary industry/industries**: Biotechnology / Rare Disease Pharmaceuticals
- **Target customers**: Healthcare providers, patients, and families affected by rare liver diseases (Alagille syndrome, Progressive Familial Intrahepatic Cholestasis, and other cholestatic conditions); B2B relationships with payers, distributors, and healthcare systems globally.
- **Mission or purpose statement**: "Relentlessly Rare" — focused on conditions where the burden is profound and the need is greatest, combining deep expertise with disciplined execution to advance meaningful medicines for people around the world.

## Products & Services
- **LIVMARLI® (maralixibat)**: An oral, once-daily ileal bile acid transporter (IBAT) inhibitor approved for the treatment of cholestatic pruritus in Alagille syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC). Approved in multiple regions including the US and Europe. Additional development programs are underway.
- **Pipeline Programs**: A broad pipeline of investigational medicines targeting significant unmet needs in rare liver diseases, including additional indications for LIVMARLI and other early-stage programs.

## Market Standing
- **Valuation/Market Cap**: As of mid-2025, Mirum’s market capitalization is approximately $1.5–$2.0 billion (fluctuating with stock price; check current data on [ir.mirumpharma.com](https://ir.mirumpharma.com/overview/default.aspx)).
- **Key Metric**: Annual Revenue — Mirum generates revenue from commercial sales of LIVMARLI. In 2024, the company reported total revenue of approximately $290 million (preliminary figure; verify in latest 10-K). The company has transitioned from a development-stage to a commercial-stage biotech.
- **Notable Investors/Partners**: Public institutional investors; key partners include clinical sites, patient advocacy groups (e.g., Alagille Syndrome Alliance, PFIC Network), and global distribution partners for international markets.
- **Growth Signals**: Three approved medicines in its portfolio; global footprint with offices in North America and Europe; expanding pipeline with additional clinical programs; consistent revenue growth from LIVMARLI; growing commercial presence in Europe and other regions.

## Competitive Advantages
- **First-in-class / Best-in-class therapy**: LIVMARLI is the first and only approved treatment for cholestatic pruritus in Alagille syndrome, addressing a critical unmet need with no prior approved therapies.
- **Deep rare disease expertise**: The leadership team has extensive experience in rare disease drug development, regulatory strategy, and commercialization, allowing the company to navigate complex pathways efficiently.
- **Patient-centric culture**: Mirum embeds patient and family voices directly into development and commercial strategy, ensuring therapies meet real-world needs.
- **Disciplined execution**: The company was founded with a single deprioritized asset and rapidly advanced it to approval, demonstrating agility and focus.

## Strategic Focus
- **Expand global access**: Continuing to secure regulatory approvals and market access for LIVMARLI and other pipeline assets across North America, Europe, and other regions.
- **Advance pipeline**: Pursuing additional indications for LIVMARLI and developing new therapies for other rare liver diseases with high unmet need.
- **Deepen patient engagement**: Strengthening relationships with patient communities and advocacy groups to inform research, development, and commercialization.
- **Build commercial infrastructure**: Expanding commercial, medical affairs, and patient services teams globally to support growing product portfolio.

## Why Work Here
- **Mission-driven culture**: Mirum’s core values — "Care, Be Real, Get It Done, and Have Fun, Seriously" — foster a collaborative, high-performance environment where employees are empowered to bring their authentic selves to work.
- **Flexible work environment**: The company supports flexible ways of working, with offices in Foster City (global HQ), Basel (Switzerland), and Zug (Switzerland), plus US Remote roles available for certain positions. Arrangements vary by role.
- **Comprehensive benefits**: 100% employee medical premium coverage (with 100% dependent medical contributions), 4% 401(k) match with immediate vesting, 15% Employee Stock Purchase Plan, four weeks of PTO starting day one, company holidays including a winter shutdown, paid parental leave, up to $5,000 annual tuition reimbursement, and an Employee Assistance Program.
- **Collaborative community**: Regular "Coffee and Chats" and bi-weekly "Lunch Connections" foster cross-functional dialogue. Office environments are designed for connection with stocked snacks, beverages, and (in some locations) catered lunches and on-site baristas.
- **Growth opportunity**: As a high-growth public company with approved products and an expanding pipeline, employees have significant opportunities to contribute to meaningful milestones and career development.

## Sources
1. [mirumpharma.com](https://mirumpharma.com/)
2. [mirumpharma.com/about-us/our-story/](https://mirumpharma.com/about-us/our-story/)
3. [mirumpharma.com/jobs/](https://mirumpharma.com/jobs/)
4. [ir.mirumpharma.com](https://ir.mirumpharma.com/overview/default.aspx)
5. [job-boards.greenhouse.io/mirumpharmaceuticals](https://job-boards.greenhouse.io/mirumpharmaceuticals)

## Other roles at Mirum Pharmaceuticals

- [Director, Regulatory Project Management](https://feeny.ai/job/director-regulatory-project-management-mirum-pharmaceuticals-foster-city-4jg70n1k4q9c) — Foster City, CA
- [Director, Clinical Pharmacology](https://feeny.ai/job/director-clinical-pharmacology-mirum-pharmaceuticals-foster-city-hgkvgcbm9zz4) — Foster City, CA
- [Associate Director, Commercial Operations](https://feeny.ai/job/associate-director-commercial-operations-mirum-pharmaceuticals-zug-8badj97bpf21) — Zug, Switzerland
- [Therapeutic Account Manager, Liver - Baltimore](https://feeny.ai/job/therapeutic-account-manager-liver-baltimore-mirum-pharmaceuticals-baltimore-wsmckesc300t) — Baltimore, MD
- [Senior Director, Regulatory Affairs](https://feeny.ai/job/senior-director-regulatory-affairs-mirum-pharmaceuticals-foster-city-c00xsafh10k8) — Foster City, CA
- [Senior Director, Shared Services](https://feeny.ai/job/senior-director-shared-services-mirum-pharmaceuticals-foster-city-aedy0jj99pbz) — Foster City, CA
- [Therapeutic Account Manager, Liver - Houston](https://feeny.ai/job/therapeutic-account-manager-liver-houston-mirum-pharmaceuticals-houston-5vf1svcn56sh) — Houston, TX
- [Therapeutic Account Manager, Liver - Grand Rapids](https://feeny.ai/job/therapeutic-account-manager-liver-grand-rapids-mirum-pharmaceuticals-grand-8a4j417qp3wd) — Grand Rapids, MI
- [Therapeutic Account Manager, Liver - Dallas](https://feeny.ai/job/therapeutic-account-manager-liver-dallas-mirum-pharmaceuticals-dallas-ypgscmz65nhr) — Dallas, TX
- [Therapeutic Account Manager, Liver - Los Angeles North](https://feeny.ai/job/therapeutic-account-manager-liver-los-angeles-north-mirum-pharmaceuticals-los-hgqjwnqq6w0h) — Los Angeles, CA