--- title: 'Senior Director, Medical Strategy and Operations at Alumis' canonical: 'https://feeny.ai/job/senior-director-medical-strategy-and-operations-alumis-united-states-bsawqvwmzrka' type: 'job' last_seen: '2026-09-15' --- # Senior Director, Medical Strategy and Operations at Alumis - **Company:** Alumis - **Location:** United States - **Posted:** 2026-04-30 - **Last confirmed live:** 2026-09-15 - **Apply:** https://job-boards.greenhouse.io/alumis/jobs/5202649008 ## Job description Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. This role will serve as a strategic and operational partner to the Vice President of Medical Affairs and Medical leadership team, and is responsible for ensuring that medical capabilities, processes, systems, and execution models are efficient, compliant, scalable, and aligned with Alumis’ growth strategy. The Senior Director, Medical Strategy and Operations, will be responsible for advancing key initiatives aimed at optimizing and showcasing the impact of the Medical Affairs team. This is a hands-on position that includes driving medical strategic initiatives, enhancing the Medical Affairs systems, supporting critical medical insights processes, and developing innovative solutions to measure and report on medical affairs performance and impact. The role demands an individual who combines scientific knowledge with strong operational leadership to thrive in a fast-paced, agile environment to elevate our medical affairs capabilities. Key Responsibilities: Strategic Leadership: - Lead and drive the development and execution of initiatives that elevate the strategic and operational effectiveness of the Medical Affairs team in a consistent and scalable manner. Medical Affairs Systems Optimization: - Oversee the design, implementation, and optimization of our Medical Affairs systems to improve internal efficiencies, engagement and communications with key opinion leaders (KOLs), healthcare providers, and other relevant stakeholders. - Lead continuous improvement initiatives to enhance efficiency, quality, and compliance across the Medical function. - Implement best practices for operational metrics, KPIs, dashboards, and reporting to support data-driven decision-making. Medical Insights: - Collaborate with Medical Affairs Leadership to collect, analyze, and integrate valuable medical insights that inform strategic decisions and optimize the impact of our medical programs. Content Management: - Serve as Medical Affairs content owner through review and approval process for external-facing materials. Cross-functional Collaboration - Collaborate with other functional areas such as Clinical Development, Marketing, Market Access, Commercial, Analytics, Compliance, and Regulatory to ensure alignment and integration of medical excellence within the broader organizational strategy. Guidance and SOP Development: - Leverage expertise to develop guidance documents and SOPs to foster consistency, clarity, and accountability across Medical Affairs. Planning, Budgeting & Resource Management - Lead medical annual planning, forecasting, and budget management. - Optimize headcount planning, vendor strategy, and external spend to maximize impact and efficiency. - Provide transparency and insights into medical investments and their impact. Qualifications: - Experience: Minimum of 10 years in Medical Affairs leadership. Proven experience in managing and optimizing medical operations, systems, content, and medical insights. Experience in a fast-paced, small biotech environment a plus - Education: Advanced degree (PhD, MD, MBA, PharmD or similar) - Leadership Skills: Exceptional leadership abilities with a demonstrated ability to manage cross-functional teams and drive change across complex medical operations. Must have track record of effectively leading without authority - Operational Expertise: Strong experience in developing and managing Medical Affairs dashboards and other qualitative outcomes to measure impact and performance. - Strategic Thinking: Ability to develop and implement strategic initiatives aligned cross-functionally that drive organizational goals and enhance the impact of Medical Affairs functions. - Strong Communication: Excellent communication and interpersonal skills, with the ability to engage and influence stakeholders at all levels, both internally and externally. The salary range for this position is $265,00 USD to 310,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices degree and background. Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. Other benefits include: - Health insurance premiums paid at 90% for employee, 80% for dependents - Free access to Genentech Bus & Ferry Share program - $100 monthly cell phone stipend - Unlimited PTO for Exempt employees - Free onsite gym and a kitchen stocked with yummy snacks and drinks! We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way. Alumis Inc. is an equal opportunity employer. ## About Alumis ## Company Overview - **One-liner**: Alumis is a public biotechnology company pioneering precision-targeted therapies for immune-mediated diseases, with a late-stage pipeline and proprietary data analytics platform. - **Entity Type**: Public (ticker symbol not confirmed in available sources; reports quarterly financials as a public company) - **Headquarters**: South San Francisco, California, United States - **Founded**: 2021 - **Founders**: Incubated by Foresite Labs; leadership includes Martin Babler (President, CEO and Chairman of the Board) ## Core Business - **Primary industry**: Biotechnology – immune-mediated disease therapeutics. - **Target customers**: Patients with immune-mediated diseases (e.g., psoriasis, lupus), physicians, and healthcare systems (B2B/B2C). - **Mission statement**: Transform treatment for immune-mediated diseases, empower people to reimagine their lives. ## Products & Services - **Envudeucitinib (oral TYK2 inhibitor)**: Late-stage candidate for plaque psoriasis; Phase 3 trials demonstrated early and robust improvements in skin clearance, quality of life, and psoriasis symptoms. Designed as a next-generation oral therapy. - **Proprietary Data Analytics Platform**: Internal platform that integrates scientific insights to select the right target, molecule, indication, patient, and endpoint. - **Pipeline of targeted therapies**: Additional programs for other immune-mediated diseases (specific indications not publicly detailed), all aiming to replace broad immunosuppression with precise treatments. ## Market Standing - **Valuation/Market Cap**: Not disclosed in available sources. - **Key Metric**: Total funding (private) not publicly available; as a public company, annual revenue is not yet disclosed (likely pre-revenue or early commercial stage). - **Notable Investors/Partners**: Incubated by Foresite Labs; board includes members from Foresite Capital, Arvinas, and other biotech leadership. - **Growth Signals**: - Active late-stage Phase 3 trials with positive results for plaque psoriasis (March 2026). - Employee headcount of 246 (as of mid-2026), growing ~1.3% monthly. - 13 active job postings, up 30% in the month prior. - Listed job openings span Clinical Development, Commercial, Research & Technical Operations, and G&A. ## Competitive Advantages - **Precision approach**: Proprietary data analytics platform enables smarter target selection and clinical trial design, reducing failure risk. - **Late-stage portfolio**: Envudeucitinib already in Phase 3, targeting a large market (plaque psoriasis) with potential to become a leading oral therapy. - **Experienced leadership**: Deep biotech expertise from CEO Martin Babler and a seasoned leadership team. - **Focus on patient outcomes**: Differentiates from broad immunosuppressants by aiming for efficacy without life-limiting side effects. ## Strategic Focus - Advance Envudeucitinib through regulatory approval and launch for plaque psoriasis. - Expand pipeline into additional immune-mediated indications (rheumatology, lupus, etc.). - Leverage data analytics to optimize clinical development and commercialization. - Build commercial infrastructure (hiring VP of Medical Affairs, Director of Market Access, etc.). ## Why Work Here - **Culture**: Emphasizes openness, collaboration, and respect; employee-led Culture Team drives engagement, growth, and inclusion. - **Values**: Challenge conventional wisdom, nurture teammates, elevate each other. - **Benefits**: Medical, dental, vision, 401k, unlimited time off, pet insurance, Employee Stock Purchase Plan, commuter benefits (including company-paid access to Genentech Bus and Ferry lines). - **Work Environment**: Mostly based in South San Francisco; some roles offer remote flexibility (indicated as "United States" in job listings). Hybrid likely for local roles. - **Growth**: High-performance, mission-driven environment with expanding headcount and pipeline; opportunity to impact transformative therapies. - **Job Openings**: Currently hiring for senior scientific, clinical, commercial, and operational roles (Associate Director Biostatistics, Vice President Medical Affairs, Director Market Access, etc.). ## Sources 1. [alumis.com – Company Website](https://www.alumis.com/) 2. [alumis.com – Careers Page](https://www.alumis.com/careers/) 3. [alumis.com – About / Leadership](https://www.alumis.com/about/) 4. [alumis.com – Job Opportunities](https://www.alumis.com/careers/job-opportunities/) 5. 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