--- title: 'Senior Director, Total Rewards and HRIS at Vir Biotechnology' canonical: 'https://feeny.ai/job/senior-director-total-rewards-and-hris-vir-biotechnology-san-francisco-cbww9w8dee7n' type: 'job' last_seen: '2026-10-17' --- # Senior Director, Total Rewards and HRIS at Vir Biotechnology - **Company:** Vir Biotechnology - **Location:** San Francisco, CA - **Posted:** 2026-10-01 - **Last confirmed live:** 2026-10-17 - **Apply:** https://job-boards.greenhouse.io/virbiotechnologyinc/jobs/4739639005 ## Job description Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies. Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company. We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best. ## THE OPPORTUNITY Reporting to the CHRO, the Sr Director of Total Rewards and HRIS will lead the design, delivery, and governance of Vir Bio's global compensation and benefits programs. You will also be responsible for the strategy and implementation of HR analytics initiatives and HRIS oversight across the HR function and broader organization. In this role you will partner with senior business leaders and the HR leadership team to translate business strategy into total rewards strategies that attract, reward, and retain key talent. You will ensure programs are competitive, equitable, and aligned with organizational objectives. The ideal candidate will be a hands-on leader with deep compensation and benefits expertise, strong analytical capabilities, and a track record of developing successful strategies. This position requires the ability to balance strategic thinking with tactical execution-conceptualizing innovative solutions while driving day-to-day program administration and continuous improvement. This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office. ## WHAT YOU'LL DO - Lead the strategic design, implementation, and administration of global compensation and benefits programs, including base pay structures, short-term and long-term incentive plans (including commercial sales incentive plans), recurring compensation cycles, and program targets - Design and implement benefits programs through needs analysis, competitive benchmarking, and cost-effectiveness evaluation - Manage annual benefit enrollment, plan changes, wellness initiatives, and compensation planning cycles - Conduct competitive market analysis to ensure programs remain competitive, equitable, and aligned with business objectives - Ensure compliance with federal, state, and international compensation and benefits regulations - Serve as the hands-on lead for executive compensation, including program design and benchmarking - Prepare and present analyses and recommendations to senior leadership, the Board of Directors, and the Compensation Committee - Strategically lead all aspects of management and coordination with the Compensation Committee including meeting planning, deliverable preparation, meeting facilitation, and tracking of follow up actions. - Align compensation programs with performance management processes to drive accountability and reward performance - Oversee global mobility programs including immigration and relocation - Develop and implement HR analytics strategy and provide HRIS oversight to ensure data integrity - Execute total rewards communication strategies to ensure employees understand and value their compensation and benefits - Manage a high-performing team across compensation, benefits, and analytics functions ## WHO YOU ARE AND WHAT YOU BRING - BA/BS and 12+ years or MS/MBA and 10+ years of relevant experience - Proven track record leading compensation and benefits teams at a public company - Experience within a commercial-stage life sciences organization is strongly preferred - Deep expertise in executive compensation programs, including presenting to Board of Directors, Compensation Committees, and external stakeholders - Comprehensive knowledge of compensation regulatory, compliance, and legislative requirements - Strong analytical capabilities with experience performing complex reporting and analysis - Superior executive presence and communication skills with ability to present credibly at all organizational levels - Proven ability to build trust with stakeholders through strong organizational skills and proactive problem-solving - Experience with HRIS systems, including UKG - Strong people management skills with a track record of developing high-performing teams - Experience managing vendor relationships with benefits brokers, consultants, and external partners - Collaborative leadership style with a hands-on approach to problem-solving and stakeholder engagement ## #LI-AS1 #LI-Onsite ## WHO WE ARE AND WHAT WE OFFER The expected salary range for this position is $227,500 to $318,000 per year. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors. Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications. All full-time employees receive a package that includes compensation, bonus and equity as well as many other Vir Biotechnology benefits and perks such as health and welfare benefit plans, non-accrual paid time off, company shut down for holidays, commuter benefits, 401K match and lunch each day in the office. Applicants must currently be authorized to work for any employer in the U.S.  We are unable to sponsor or take over sponsorship of an employment Visa at this time. All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics. This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs.  Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment. Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees. For hires based in the United States, Vir Biotechnology, participates in [E-Verify](https://www.e-verify.gov/sites/default/files/everify/posters/EVerifyParticipationPoster.pdf). [Candidate Privacy Notice](https://www.vir.bio/candidate-notice/) ## About Vir Biotechnology ## Company Overview - **One-liner**: Vir Biotechnology is a clinical-stage immunology company focused on engineering powerful antibody-based medicines to treat infectious diseases and cancer. - **Entity Type**: Public (Ticker: VIR) - **Headquarters**: San Francisco, California, United States - **Founded**: 2016 - **Founders**: Not publicly available (the company was formed with founding investments from ARCH Venture Partners, the Bill & Melinda Gates Foundation, and others) ## Core Business - **Primary Industry**: Biotechnology (Immunology, Infectious Disease, Oncology) - **Target Customers**: Patients with serious infectious diseases (e.g., chronic hepatitis delta, COVID-19, Ebola) and specific cancers; the company's customers are effectively patients and healthcare systems, with revenue coming from partnerships and product sales. - **Mission/Purpose**: "Power the immune system to transform lives" by delivering potentially transformative medicines for patients with high unmet medical needs. ## Products & Services - **Next-Generation Antibody Platform**: A proprietary platform that enables the rapid discovery, optimization, and advancement of antibody candidates for infectious diseases. - **PRO-XTEN® Protease-Releasable Masking Technology**: A platform (exclusive rights for oncology and infectious disease) used to engineer conditionally activated antibodies that are designed to be safer and more effective in treating cancer. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company. - **Pipeline Programs**: The company’s pipeline includes leading programs in chronic hepatitis delta virus (HDV) and strategically expanding into oncology. They have demonstrated their ability to discover and develop antibody-based medicines for COVID-19 and Ebola. ## Market Standing - **Valuation/Market Cap**: Market cap fluctuates with stock price. As of recent reporting, it is in the range of several billion USD. For the most current figure, refer to financial data providers. - **Key Metric**: As a public company, key metrics include R&D spending, cash position, and pipeline progress. The company had significant revenue from its COVID-19 antibody partnership (sotrovimab) but is now focused on advancing its pipeline. - **Notable Investors/Partners**: Founding investors include ARCH Venture Partners and the Bill & Melinda Gates Foundation. Key partners include Alnylam Pharmaceuticals and Sanofi (via the Amunix/PRO-XTEN platform). - **Growth Signals**: The company is actively expanding its oncology pipeline, appointing an SVP of Oncology and a Vice President of Clinical Research-Oncology. It continues to hire across R&D, regulatory, and business development, signaling a phase of growth and pipeline advancement. ## Competitive Advantages - **Deep Immunology Expertise**: The company has a world-class team with deep knowledge of immunology and antibody engineering. - **Dual-Platform Strategy**: Combining a powerful antibody discovery platform with the PRO-XTEN® masking technology gives it a unique ability to create both potent and safer therapies. - **Proven Track Record**: Successfully developed and brought to market a COVID-19 antibody (sotrovimab) and an Ebola treatment (mAb114) on an accelerated timeline, demonstrating execution capability. - **Focus on Unmet Needs**: Concentrates on diseases with limited treatment options, such as chronic hepatitis delta and hard-to-treat cancers. ## Strategic Focus - **Infectious Disease Foundation**: Continuing to advance its core programs in infectious diseases, with a leading program in chronic hepatitis delta. - **Strategic Oncology Expansion**: Building a robust oncology pipeline using its antibody and PRO-XTEN® platforms, with a focus on indications with high unmet need. - **Pipeline Acceleration**: Leveraging its platforms to rapidly identify, optimize, and advance candidates from concept to clinic. - **Building for the Long Term**: The company is strategically building its capabilities and team to become a multi-product, multi-indication biotech. ## Why Work Here - **Mission-Driven**: Employees are directly contributing to developing transformative medicines for patients with serious diseases. - **World-Class Team**: Opportunity to work alongside industry-leading scientists, clinicians, and business leaders in the U.S. and Europe. - **Commitment to Fair Pay**: The company has an "unwavering commitment to fair pay" with a rigorous, proactive approach to compensation based on skills and experience. U.S. salary ranges are shared internally for transparency. - **Generous Benefits**: Includes health benefits and wellness program, unaccrued time off with structured holidays, on-site paid parking, lunch, and transit spending account (in the U.S.). - **Workplace Culture**: The company emphasizes "Virtues" over values and a culture of urgency and impact. - **Locations**: Primarily San Francisco, CA, with some remote options for specific roles (e.g., Regulatory Writer). European offices are also part of the company. ## Sources 1. [vir.bio](https://www.vir.bio/) 2. [vir.bio/careers](https://www.vir.bio/careers/) 3. [job-boards.greenhouse.io/virbiotechnologyinc](http://job-boards.greenhouse.io/virbiotechnologyinc) 4. [vir.bio/about/strategy](https://www.vir.bio/about/strategy/) ## Other roles at Vir Biotechnology - [Senior Director, Head of Clinical Pharmacology](https://feeny.ai/job/senior-director-head-of-clinical-pharmacology-vir-biotechnology-united-states-3rhq3yhvnnf1) — United States - [SVP, Regulatory Affairs](https://feeny.ai/job/svp-regulatory-affairs-vir-biotechnology-san-francisco-q3eswvctgp3v) — San Francisco, CA - [Director, Clinical Contracts](https://feeny.ai/job/director-clinical-contracts-vir-biotechnology-san-francisco-ann0130xxcqz) — San Francisco, CA - [Senior Director, Clinical Research-Program Executive-Oncology](https://feeny.ai/job/senior-director-clinical-research-program-executive-oncology-vir-biotechnology-r41tr7w00x99) — San Francisco, CA - [Director, Clinical Operations](https://feeny.ai/job/director-clinical-operations-vir-biotechnology-san-francisco-ajxvfttp1cq5) — San Francisco, CA - [Associate Director, Clinical Scientist](https://feeny.ai/job/associate-director-clinical-scientist-vir-biotechnology-san-francisco-kz6ttfjzvf2m) — San Francisco, CA - [Associate Director, CMC Project Management](https://feeny.ai/job/associate-director-cmc-project-management-vir-biotechnology-san-francisco-rgwkehm4691f) — San Francisco, CA - [Associate Director, Quality Systems (Temporary)](https://feeny.ai/job/associate-director-quality-systems-temporary-vir-biotechnology-san-francisco-x0xjcec1q94g) — San Francisco, CA - [Senior Specialist, QA Operations (Temporary)](https://feeny.ai/job/senior-specialist-qa-operations-temporary-vir-biotechnology-san-francisco-mjvvaa0hjtne) — San Francisco, CA - [Senior Scientist I, Drug Product & Device Development (Temporary)](https://feeny.ai/job/senior-scientist-i-drug-product-device-development-temporary-vir-biotechnology-yxcegjgez7qk) — San Francisco, CA