---
title: 'Senior In-House Clinical Research Associate at Immunome, Inc.'
canonical: 'https://feeny.ai/job/senior-in-house-clinical-research-associate-immunome-inc-bothell-washington-xd757hs9sz89'
type: 'job'
last_seen: '2026-09-12'
---

# Senior In-House Clinical Research Associate at Immunome, Inc.

- **Company:** Immunome, Inc.
- **Location:** Bothell Washington, United States
- **Compensation:** $128k–$156k
- **Posted:** 2026-09-09
- **Last confirmed live:** 2026-09-12
- **Apply:** https://job-boards.greenhouse.io/immunomeinc/jobs/5419581008

## Job description

Company Overview

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.

Position Overview

The Senior In-house Clinical Research Associate (Sr. IHCRA) provides hands-on support for the day-to-day execution of clinical trial activities as assigned by Clinical Project Delivery (CPD) and/or Clinical Site and Trial Operations (CSTO).  They operate in compliance with protocols, ICH-GCP, and applicable regulation, and Standard Operating Procedures (SOPs).

This role supports functional activities across assigned trials, sites, and vendors throughout the trial lifecycle, under the guidance and oversight of CPD and CSTO to help ensure timely, compliant trial execution.

The person in this position may participate in cross-trial process improvement initiatives and may also provide guidance to new or more junior team members.

## Responsibilities

Project Delivery and Trial Execution Support

- Assist with completion of assigned project delivery and clinical trial operational tasks in compliance with ICH-GCP, applicable SOPs, and protocols.
- Help implement various study tracking tools and contribute to the development of study-level documents.
- Maintain study timelines as assigned.
- Assist with data review, protocol deviation review, and the query process as assigned
- Contribute to the development, maintenance and quality control of trial documentation, including study manuals, plans, protocols, instructions, trackers, worksheets, and presentations.
- Help ensure completeness, maintenance, and quality of the Trial Master File.

Site Management and Monitoring Support

- Support site management and monitoring activities as assigned, including tasks related to site selection and activation, investigational product (IP) and clinical supplies management, site monitoring visit preparation, site-level Informed Consent review, and site contracts management.
- Help develop, distribute, review, track, and file essential documents and study binder documents, troubleshooting related issues to ensure on time delivery at all stages.
- Maintain site- and participant-level tracking.
- Support data cleaning activities as assigned

Vendor Management Support

- Assist with day-to-vendor management activities including tracking and workflow management of vendor contracts.
- Support change order and change notification tracking, as assigned.
- May serve as day-to-day vendor contact for assigned activities.
- Participate in vendor teleconferences, record meeting minutes, track action items and decisions.
- Assist with invoice review and budget tracking.

Cross-Functional Collaboration

- Collaborate with the clinical study team members as assigned to support consistency and efficiency of trial execution.
- Develop and maintain positive, effective, and collaborative working relationships with team members and vendors.
- Help onboard and guide new or junior team members.

## Qualifications

- Bachelor’s degree with 3 years of clinical project or trial management experience in the biotechnology or pharmaceutical industry, or an equivalent combination of education and experience.
- Demonstrated experience with site management and vendor management activities, including CROs and central labs.
- Demonstrated experience with trial documentation and Trial Master File management.

Knowledge and Skills

- Working knowledge of clinical trial processes, and ICH-GCP.
- Strong organizational skills with the ability to manage multiple competing tasks.
- Ability to effectively work cross-functionally and build relationships with stakeholders without direct authority.
- Strong communication and interpersonal skills.
- Detail-oriented with an analytical approach to problem-solving.
- Able to prioritize and manage multiple tasks and projects in a fast-paced, dynamic environment.
- Highly professional, adaptable, and accountable.

Washington State Pay Range $127,890—$155,682 USD

E/E/O

Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

E-Verify

Immunome, Inc. is a participant in E-Verify. Please review the following notices: [E-Verify Participation Poster](https://immunome.box.com/s/bopxukipfidxjscs4bjxt75f90bvpppk) | https://immunome.box.com/s/r51g9subw1wqni9xkutbl6up635sjr8e | https://immunome.box.com/s/r3ekbimwh988my9vzl76tnlbg60zvh9u.

## About Immunome, Inc.

## Company Overview
- **One-liner**: Immunome is a clinical-stage oncology company developing first-in-class and best-in-class targeted cancer therapies, with a primary focus on antibody-drug conjugates (ADCs).
- **Entity Type**: Public (Nasdaq: IMNM)
- **Headquarters**: Bothell, Washington, United States
- **Founded**: The company was formed through a merger of Morphimmune and Immunome in October 2023.
- **Founders**: The company is led by Clay Siegall, Ph.D. (Chairman, CEO, and President), who co-founded Seagen. The original Immunome entity was founded earlier, but the current company structure dates to the 2023 merger.

## Core Business
- Primary industry/industries: Biotechnology, Oncology, Drug Discovery & Development
- Target customers: Patients with cancer, healthcare providers, and clinical trial sites. The company is a B2B/B2C entity in the healthcare and life sciences space.
- Mission or purpose statement: "Our mission is to improve outcomes for cancer patients by advancing and expanding a portfolio of first-in-class and best-in-class therapeutic candidates." [immunome.com](https://immunome.com/)

## Products & Services
- **Varegacestat (formerly AL102)**: A late-clinical stage gamma secretase inhibitor for the treatment of desmoid tumors. The company submitted a New Drug Application (NDA) to the U.S. FDA in April 2026. [investors.immunome.com](https://investors.immunome.com/)
- **IM-1021**: A ROR1-targeted antibody-drug conjugate (ADC) currently in a Phase 1 trial.
- **IM-3050**: A FAP-targeted radioligand which received IND clearance in Q1 2025.
- **Preclinical ADC Pipeline (IM-1617, IM-1340, IM-1335)**: ADCs pursuing undisclosed targets with expression in multiple solid tumors. IM-1617 had its first patient dosed in a Phase 1 trial in June 2026. [investors.immunome.com](https://investors.immunome.com/)

## Market Standing
- **Valuation/Market Cap**: Not publicly available in the search results. As a public company, this fluctuates. (Check recent filings for current data).
- **Key Metric**: The company is pre-revenue (clinical-stage) and has raised significant capital. Since the 2023 merger, CEO Clay Siegall has raised $355 million in equity financings. [immunome.com](https://immunome.com/about/)
- **Notable Investors/Partners**: The company is publicly traded. Key leadership previously worked at Seagen (acquired by Pfizer for $43 billion).
- **Growth Signals**: The company is rapidly advancing its pipeline. Key milestones include the NDA submission for varegacestat, first patient dosed for IM-1617, and positive Phase 3 data presented at ASCO 2026. The company currently lists 32 open positions on its careers page, indicating strong hiring momentum. [job-boards.greenhouse.io](http://job-boards.greenhouse.io/immunomeinc)

## Competitive Advantages
- **World-Class Leadership**: The executive team, led by Seagen co-founder Clay Siegall, has deep experience in designing, developing, and commercializing blockbuster ADCs (ADCETRIS, PADCEV, TIVDAK, TUKYSA). [immunome.com](https://immunome.com/about/)
- **Proprietary ADC Platform**: A systematic, data-driven process for optimizing antibodies, linkers, and payloads to create differentiated ADCs. [immunome.com](https://immunome.com/)
- **Near-Term Catalyst**: The NDA submission for varegacestat provides a potential near-term commercial opportunity.
- **Strong Financial Backing**: Raised $355M in equity since the merger, providing a solid runway for pipeline advancement.

## Strategic Focus
- **Advancing the Pipeline**: The primary focus is on executing clinical trials for varegacestat (Phase 3), IM-1021 (Phase 1), and IM-3050 (Phase 1), and advancing preclinical ADCs into the clinic.
- **Regulatory Filing**: Successfully navigating the FDA NDA submission and potential approval for varegacestat.
- **Discovery & Expansion**: Using their ADC discovery platform to generate new candidates and identify and acquire targeted oncology assets to expand the portfolio. [immunome.com](https://immunome.com/about/)

## Why Work Here
- **Mission-Driven**: The work directly impacts the lives of cancer patients, with a stated goal of developing transformative therapies. [immunome.com](https://immunome.com/about/)
- **High-Impact Team**: Opportunity to work with "some of the brightest and most experienced minds in ADC development," including leaders who have brought multiple drugs to market. [immunome.com](https://immunome.com/careers/)
- **Growth Stage**: With 32 open roles, the company is in a rapid growth phase, offering significant career advancement opportunities. [job-boards.greenhouse.io](http://job-boards.greenhouse.io/immunomeinc)
- **Comprehensive Benefits**: Includes 100% company-paid medical premiums for employees, a 401(k) with employer match, paid parental leave, and a week-long winter break. [immunome.com](https://immunome.com/careers/)
- **Location & Culture**: Based in Bothell, WA. The company describes a culture of "innovative, collaborative environment where employees are empowered to do their best work." [immunome.com](https://immunome.com/careers/)

## Sources
1. [Immunome Official Website](https://immunome.com/)
2. [Immunome About Page](https://immunome.com/about/)
3. [Immunome Investor Relations](https://investors.immunome.com/)
4. [Immunome Careers Page](https://immunome.com/careers/)
5. [Immunome Jobs on Greenhouse](http://job-boards.greenhouse.io/immunomeinc)

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