---
title: 'Senior Informatics Engineer at Eikon Therapeutics'
canonical: 'https://feeny.ai/job/senior-informatics-engineer-eikon-therapeutics-millbrae-2g6dsjx5a73z'
type: 'job'
last_seen: '2026-09-06'
---

# Senior Informatics Engineer at Eikon Therapeutics

- **Company:** Eikon Therapeutics
- **Location:** Millbrae, CA
- **Posted:** 2026-08-14
- **Last confirmed live:** 2026-09-06
- **Apply:** https://job-boards.greenhouse.io/eikontherapeutics/jobs/5210573007

## Job description

Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.

Position

We are currently seeking an experienced Informatics Engineer to contribute to the design, implementation, and development of our informatics processes and systems in support of all phases of our research pipelines. You will work closely with our scientists and engineers to capture and manage functional requirements, and you will be a core member of a team responsible for building scalable, AI-enabled solutions that fit into our information ecosystem and ensure the integrity of our data architecture.

## About You

You are agile of mind and effectively communicate difficult concepts. You work well within a fast-paced, mission-driven, dynamic environment and possess a deep desire to pursue creative solutions with broad guidance and a high degree of independence. You are prepared to tackle a broad selection of challenges as the company grows. You can partner with R&D leadership and functional area scientists to proactively identify areas of need, design solutions, prioritize work, make “build versus buy” decisions, coordinate pilot studies, ensure appropriate system usage, and regularly report on system metrics and portfolio execution.

## What You'll Do

- Actively participate in the administration, design, implementation, integration, development, and testing of informatics solutions, including LIMS/ELN software (e.g., Dotmatics, CDD Vault), Inventory Management systems (e.g. Mosaic), and AI/ML platforms (e.g., Databricks), to support R&D projects and scientific workflows
- Design, build, and deploy AI agentic tools and LLM-powered workflows that automate scientific data processes and accelerate research decision-making
- Implement data warehouse / data lake systems and ETL pipelines to support advanced analytics and AI/ML strategy
- Design and build data automation pipelines and ETL processes that ingest, transform, and harmonize research data from multiple sources
- Collaborate with a cross-functional team to develop an end-to-end digital architecture roadmap
- Work with project stakeholders to analyze data management, data access, analytics, and visualization needs across R&D functions
- Gather user stories, design applications, implement and integrate systems, and guide the functionality of IT systems across the company
- Ensure that systems are fully documented with system requirements, architectural design, and operational plans
- Coordinate the training and support of end-users on system usage and best practices
- Participate in the design of enterprise-wide data platform architecture and ensure systems adhere to that architecture
- Stay up to date with emerging technologies and trends in LIMS engineering, AI/ML platforms, and agentic systems

## Qualifications

- BS plus 5 years of relevant experience or MS plus 3 years of relevant experience in computer science, life science, engineering, or a related field, or equivalent training, fellowship, and/or work experience
- Experience with ELN, LIMS, scientific data management, compound registration, sample inventory, instrument data capture, and assay results, such as Dotmatics and CDD Vault
- Experience with the administration, implementation, and integration of AI/ML and data lake platforms, such as Databricks
- Hands-on experience building AI agentic workflows or LLM-integrated applications, and applying them to real research or data problems
- Applicable experience in software development and/or systems integration, preferably within a scientific or laboratory environment, especially one related to drug development
- Experience with programming, scripting, and query languages and platforms such as Python, SQL, JavaScript (React) and Java
- Experience with different types of data storage implementations, relational and non-relational (e.g., key-value, document, SQL, graph databases), and optimizing data storage using a mix of approaches
- Familiarity with Docker, containerized applications, and AWS cloud computing services
- Experience documenting detailed software requirements, user stories, business processes, and/or software specifications for both custom and Commercial-Off-The-Shelf (COTS) systems
- Familiarity with laboratory operations and workflows, and experience designing, implementing, and maintaining computational workflows involving multiple modular steps
- Proven experience working closely with scientific stakeholders to understand their informatics needs, and subsequently defining complex system requirements, scope, objectives, and key results in the context of larger organizational goals
- Experience working in a life sciences or biopharmaceutical environment such as early-stage research, drug discovery, or another biological sciences discipline is preferred
- Excellent problem-solving and analytical skills in a fast-paced R&D environment where product requirements and internal software tools may change over time
- Demonstrated success working independently on initiatives of high complexity, uncertainty, and risk with minimal guidance and direction
- Able to present your work, both verbally and in writing, to diverse audiences including scientific stakeholders, technical teams, and research leadership

At Eikon, employee compensation also includes bonus and equity compensation, in addition to several generous benefit programs, including:​

- 401k plan with company matching​
- Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)​
- Mental health and wellness benefits​
- Weeklong summer and winter holiday shutdowns​
- Generous paid time off and holiday policies​
- Life/AD&D Insurance (premiums covered by Eikon at 100%) and optional supplemental employee-paid life/AD&D policies ​
- Enhanced parental leave benefit​
- Daily subsidized lunch program when on-site​

The expected salary range for this role is $134,000 to $161,700 depending on skills, competency, and the market demand for your expertise. Eikon is proud to be an equal opportunity employer and will consider all qualified applicants for employment.

We are currently not accepting any new third-party agencies or firms at this time. Please do not forward unsolicited agency resumes to our website, employees or Human Resources. Eikon Therapeutics will not pay fees to any third-party agency or firm associated with unsolicited resumes.

## About Eikon Therapeutics

## Company Overview
- **One-liner**: Eikon Therapeutics is a late-stage clinical biopharmaceutical company that integrates single-molecule imaging, machine learning, and engineering to discover and develop novel therapies for oncology, immunology, and neuroscience.
- **Entity Type**: Public (NASDAQ: EIKN) – originally privately held, went public via a post-IPO equity round in 2026.
- **Headquarters**: Millbrae, California, United States
- **Founded**: 2019
- **Founders**: Not publicly named in the search results; the company was seeded by The Column Group.

## Core Business
- **Primary industry**: Biotechnology research and drug development (therapeutics)
- **Target customers**: Patients with unmet medical needs; the company partners with clinical research organizations, healthcare providers, and regulators.
- **Mission or purpose statement**: “Better insights will lead to better medicines” – the company aims to introduce new therapies that improve and extend life by deeply understanding human disease biology.

## Products & Services
- **EIK10 (TLR7/8 agonist)**: Phase 2 clinical program for solid tumors, leveraging immune response modulation.
- **VCP inhibitor (undisclosed target)**: Phase 1 program in oncology.
- **AR-v7 degrader**: Preclinical/early clinical program targeting androgen receptor splice variant in cancer.
- **PARP1 inhibitor**: Early-stage oncology program; also a CNS-penetrant PARP1 candidate for neuroscience.
- **AR degrader**: Preclinical androgen receptor degrader.
- **Discovery-stage programs**: Multiple undisclosed targets in oncology, immunology, and neuroscience, supported by the company’s single-molecule imaging platform.

## Market Standing
- **Valuation/Market Cap**: Not disclosed in search results; total funding of ~$1.5B as of mid-2026.
- **Key Metrics**:
  - Annual Revenue: $5.6M (reflective of early-stage, pre-commercial biotech).
  - Total Funding: $1.5B (seed, Series A $148M in 2021, Series B $518M in 2022, Series C $106M in 2023, and post-IPO equity of $381.2M in 2026).
- **Notable Investors/Partners**: The Column Group (lead seed/Series A), 18 investors in Series B, and multiple institutional partners across rounds; board includes industry veterans (e.g., Roger Perlmutter, former Merck CEO).
- **Growth Signals**:
  - Headcount grew ~2.7% YoY to 314 employees (2025–2026).
  - Active job postings increased 270% year-over-year (as of mid-2026).
  - Expanding pipeline into immunology and neuroscience beyond oncology.
  - Recent $351M financing event (reported by multiple outlets) to fund late-stage trials.

## Competitive Advantages
- **Proprietary single-molecule imaging platform** that enables real-time observation of protein dynamics at the single-molecule level, providing insights into disease mechanisms that traditional methods miss.
- **Machine learning integration** to analyze massive imaging datasets, accelerating target identification and drug design.
- **Deep bench of scientific talent**: Executives include Roger Perlmutter (CEO, ex-Merck), Roy Baynes (CMO, ex-Merck), and a team drawing from Genentech, Bristol Myers Squibb, Pfizer, and top academic institutions.
- **Cross-disciplinary approach** merging biology, engineering, and computation under one roof, reducing the “translation gap” between discovery and clinic.

## Strategic Focus
- **Advancing late-stage oncology pipeline**: Lead program (TLR7/8 agonist) in Phase 2, with plans to move into pivotal trials.
- **Expanding into new therapeutic areas**: Significant preclinical investment in immunology and neuroscience, with CNS-penetrant PARP1 and AR programs.
- **Continued platform development**: Scaling imaging and machine learning capabilities to enable faster, more precise drug discovery across multiple indications.
- **Building commercial infrastructure**: Post-IPO financing supports preparation for potential product launches and expanded clinical operations.

## Why Work Here
- **Culture**: Values-driven environment prioritizing execution, collaboration, innovation, transparency, respect, and caring for patients and colleagues.
- **Engineering & science fusion**: Opportunity to work at the intersection of advanced imaging, machine learning, and drug development – unique in biotech.
- **Growth trajectory**: Young company with strong funding, public listing, and rapidly expanding pipeline; employees can have significant impact.
- **Compensation**: Competitive base salaries (e.g., Software Engineer ~$140k, Senior Software Engineer ~$167k) plus equity incentives.
- **Work model**: Likely office-based at the Millbrae HQ or satellite labs in Hayward, CA; clinical roles may require travel; no explicit remote/hybrid policy in search results.
- **Perks**: Not detailed, but typical biotech benefits (health, 401k, PTO) are assumed; the company emphasizes a “transparent and inclusive culture” per its values.
- **Employee sentiment**: Overall rating 3.0/5 on LinkedIn (66 reviews); work-life balance 3.2, compensation 3.4, culture 3.0, career opportunities 2.9 – indicating room for improvement in career development.

## Sources
1. [eikontx.com](https://www.eikontx.com/)
2. [eikontx.com/about-us](https://www.eikontx.com/about-us/)
3. [eikontx.com/join-us](https://www.eikontx.com/join-us/)
4. [eikontx.com/pipeline](https://www.eikontx.com/pipeline/)
5. [linkedin.com/company/eikon-therapeutics-inc](https://www.linkedin.com/company/eikon-therapeutics-inc)

## Other roles at Eikon Therapeutics

- [Associate Director, Clinical Regulatory](https://feeny.ai/job/associate-director-clinical-regulatory-eikon-therapeutics-jersey-city-k85gtnexs2a1) — Jersey City, NJ
- [Senior Clinical Trial Manager, Oncology (APAC)](https://feeny.ai/job/senior-clinical-trial-manager-oncology-apac-eikon-therapeutics-jersey-city-vq62tce7x87v) — Jersey City, NJ / Millbrae, CA
- [Senior Director, Clinical Research (Medical Director)](https://feeny.ai/job/senior-director-clinical-research-medical-director-eikon-therapeutics-jersey-mcxrw0kk581x) — Jersey City, NJ
- [Staff Software Engineer, Machine Learning and Computational Chemistry](https://feeny.ai/job/staff-software-engineer-machine-learning-and-computational-chemistry-eikon-202k9e76vmy5) — Millbrae, CA
- [Sr. Director, Regulatory Affairs](https://feeny.ai/job/sr-director-regulatory-affairs-eikon-therapeutics-jersey-city-jkyatykrntds) — Jersey City, NJ
- [Senior Director, Total Rewards](https://feeny.ai/job/senior-director-total-rewards-eikon-therapeutics-millbrae-550rjqcker3j) — Millbrae, CA
- [Senior Clinical Quality Operations Manager](https://feeny.ai/job/senior-clinical-quality-operations-manager-eikon-therapeutics-jersey-city-cktq0jdk1mn1) — Jersey City, NJ / Millbrae, CA
- [Senior Manager, Biostatistics](https://feeny.ai/job/senior-manager-biostatistics-eikon-therapeutics-jersey-city-cdzwe0z05kpz) — Jersey City, NJ
- [Senior Clinical Trial Manager, Oncology](https://feeny.ai/job/senior-clinical-trial-manager-oncology-eikon-therapeutics-millbrae-f90cz419kkaf) — Millbrae, CA / Jersey City, NJ
- [Senior Scientist, Analytical CMC](https://feeny.ai/job/senior-scientist-analytical-cmc-eikon-therapeutics-millbrae-y03yk2c2hwv6) — Millbrae, CA