---
title: 'Senior IT Engineer at Plasmidsaurus'
canonical: 'https://feeny.ai/job/senior-it-engineer-plasmidsaurus-san-francisco-37nxx70rqkjx'
type: 'job'
last_seen: '2026-10-14'
---

# Senior IT Engineer at Plasmidsaurus

- **Company:** Plasmidsaurus
- **Location:** San Francisco, CA
- **Employment:** full-time
- **Work type:** hybrid
- **Posted:** 2026-10-08
- **Last confirmed live:** 2026-10-14
- **Apply:** https://jobs.ashbyhq.com/plasmidsaurus/4fab86ab-d0e1-4de7-9c83-0e87f5022f3e

## Job description

## About Plasmidsaurus

Plasmidsaurus is on a mission to accelerate new cures and promote a healthier planet by unlocking a new level of productivity for scientists. Our sequencing services are used daily by thousands of innovators, including Nobel laureates, Fortune 100 pharma, and over 70,000 scientists.

We began by revolutionizing plasmid sequencing, making it exponentially cheaper and faster, with innovative sequencing technologies and a global network of laboratories that turn samples into answers in hours, not weeks.

Now we are expanding that same disruptive model across all of genomics. With the launch of our new RNA-seq service, we are taking a bold step toward our vision to sequence everything, providing scientists everywhere with faster, simpler, and more affordable access to the data that powers discovery.

Every team member at Plasmidsaurus plays a crucial role in driving the future of biotech research. Together, we are building the world’s most efficient sequencing engine that operates overnight, scales globally, and helps scientists make breakthroughs faster than ever before.

## Role Overview

At Plasmidsaurus, we're scaling a global network of labs where scientists, engineers, robots, and sequencing technology work together to accelerate scientific discovery. We're looking for a Senior IT Engineer to build the systems and support that keep our people productive, connected, and secure across 10 sites worldwide. You'll own our corporate IT infrastructure, from employee technology and identity management to security, compliance, and office networking, with the autonomy to improve how it all works. You will build and shape an IT function that reliably scales with the company, making it easier for everyone at Plasmidsaurus to do their best work.

## What You'll Do

Build Reliable, Scalable IT Systems

- Build and continuously improve reliable, automated IT systems and processes that support the company as it scales.
- Own the IT administration, integrations, and security of systems including Google Workspace (IdP), Rippling, and SentinelOne, ensuring reliable identity and access management, SSO/SCIM provisioning, and role-based access controls.
- Build and improve secure, automated onboarding, offboarding, device management, and access provisioning across our global workforce.
- Manage employee workstations, endpoint security, and access to corporate and on-prem systems across Mac, Windows, and Linux environments.

Own Corporate Security & Compliance

- Lead and manage our SOC 2 compliance efforts in Vanta, including developing cybersecurity policies, preparing for audits, monitoring controls, and addressing gaps.
- Own and strengthen organizational security through identity and access controls, endpoint protection, phishing prevention, vendor reviews, and security awareness
- Identify and address corporate IT security risks proactively, coordinating assessments and partnering with Platform Engineering on production infrastructure risks.

Keep Our Global Sites Connected

- Deploy, maintain, and troubleshoot office and lab networks across our 10 global sites, working with Platform Engineering on architecture, automation, and new site buildouts. Our networks use pfSense, MikroTik, Terraform, and Ansible.

You are someone who:

- Takes ownership of the IT function as a whole, building the systems, processes, and capabilities needed to support the company as it grows.
- Is equally comfortable troubleshooting a network, automating a workflow, and solving an employee's technical problem.
- Thinks ahead, proactively building solutions for the next stage rather than waiting for problems to emerge.
- Thrives in a high-agency environment where you can move quickly, make decisions, and see the impact of your work.
- Brings a service mindset without sacrificing technical rigor, security, or efficiency.
- Enjoys experimenting with new tools and technologies and finding smarter ways to work.

## Qualifications

- BS in Computer Science
- 7+ years of hands-on IT engineering or systems administration experience, ideally in a growing, technically complex company.
- Strong experience administering Google Workspace, identity and access management (SSO, SAML, SCIM), and endpoint management across Mac, Windows, and Linux.
- Experience with MDM, endpoint security, and device lifecycle management; familiarity with Rippling and SentinelOne preferred.
- Experience owning SOC 2 compliance, security controls, and audit readiness.
- Hands-on networking experience, including VLANs, DNS, DHCP, VPNs, and office infrastructure, Tailscale, pfSense and MikroTik experience preferred.
- Experience with scripting and infrastructure automation using tools such as Python, Bash, Terraform, and Ansible.
- Strong troubleshooting skills and a track record of independently improving IT systems, processes, and security.

We encourage you to apply even if your experience doesn't perfectly align with the job description as we seek out diverse and creative perspectives. Team members who love to learn and collaborate in an inclusive environment will thrive with us. We are an equal opportunity employer and do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. If you need additional accommodations to feel comfortable during your interview process, please let us know at careers@plasmidsaurus.com.

## About Plasmidsaurus

## Company Overview
- **One-liner**: Plasmidsaurus provides overnight, long-read sequencing services for plasmids, RNA, amplicons, whole genomes, AAV, and microbiomes to accelerate life science research.
- **Entity Type**: Private (Startup)
- **Headquarters**: South San Francisco, California, United States
- **Founded**: 2022
- **Founders**: James Stapleton (Co-founder and CTO), Eric Johnson (Co-founder and CSO)

## Core Business
- **Primary industry/industries**: Biotechnology Research, Genomics, Life Sciences
- **Target customers**: B2B — academic research labs, biotech startups, Fortune 100 pharmaceutical companies, and DIY biohackers
- **Mission or purpose statement**: "To accelerate new cures and promote a healthier planet by unlocking new levels of productivity for scientists."

## Products & Services
- **Whole Plasmid Sequencing**: Overnight, long-read sequencing of entire plasmids without the need for primers or minipreps, providing fully annotated maps.
- **RNA-Seq**: Ultrafast, affordable transcriptome analysis from cells, with results in as fast as 3 days.
- **Amplicon Sequencing**: Fast results for amplicons of any size, including overnight microbiome amplicon sequencing.
- **Whole Genome Sequencing**: Fast and complete genome sequences for nearly any organism.
- **AAV Genome Sequencing**: Full-length AAV genome sequences from intact capsids in 3 days, identifying potential issues other methods miss.
- **Microbiome Sequencing**: Species-level identification directly from raw environmental samples or PCR products.
- **Custom Sequencing**: Tailored sequencing solutions for specific research needs.

## Market Standing
- **Valuation/Market Cap**: Not publicly available
- **Key Metric**: Estimated annual revenue of $18.8 million (source: Datanyze)
- **Notable Investors/Partners**: Addgene (handling majority of their plasmid sequencing), Oxford Nanopore Technologies (expanded collaboration), Illumina, PacBio
- **Growth Signals**: Opened 10th global lab in Singapore (May 2025); launched ultrafast RNA-Seq service (Oct 2025); launched fast, low-input AAV genome sequencing service (May 2025); cited in over 2,500 publications; trusted by Nobel laureates, Fortune 100 pharma, and over 70,000 scientists; 110 employees with operations in 6 countries; website traffic up 63% year-over-year.

## Competitive Advantages
- **Speed and convenience**: Overnight turnaround for most services, with a global network of 1,000+ dropboxes and labs operating across multiple time zones (San Francisco, San Diego, Los Angeles, Seattle, Eugene, Louisville, Boston, London, Cologne, Singapore).
- **Technology leadership**: Pioneered Whole Plasmid Sequencing; partners with leading sequencing technology providers (Oxford Nanopore, PacBio, Illumina) for early access to latest chemistries and hardware.
- **Accuracy and reliability**: In an independent challenge study, Plasmidsaurus delivered the fastest and most accurate results on low concentration, degraded, and complex plasmids compared to leading vendors.
- **Simplicity**: No primers or minipreps needed; simple online ordering with PO, credit card, or "dinocoins"; results delivered as fully annotated maps straight to inbox.
- **Scale and trust**: Trusted by Nobel laureates, Fortune 100 pharma, and over 70,000 scientists; cited in 2,500+ publications.

## Strategic Focus
- **Expanding service menu**: Moving beyond plasmid sequencing into RNA-Seq, AAV genome sequencing, microbiome, and whole genome sequencing — aiming to "sequence everything."
- **Global scaling**: Opening new labs worldwide (10th lab in Singapore, May 2025) to enable overnight turnaround across time zones.
- **Product innovation**: Continuously launching ultrafast, low-input services (e.g., ultrafast RNA-Seq, low-input AAV sequencing) to reduce barriers for researchers.
- **Partnerships**: Deepening collaboration with Oxford Nanopore Technologies and other leading sequencing technology providers.

## Why Work Here
- **Mission-driven**: Directly contribute to accelerating new cures and promoting a healthier planet by making sequencing faster, cheaper, and more accessible.
- **High-growth environment**: Rapidly scaling company (founded 2022, now 110 employees across 6 countries) with strong revenue growth and expanding service lines.
- **Global, distributed team**: Labs in 10 cities across the US, UK, Germany, Singapore, Finland, and India; hybrid/remote-friendly roles available (e.g., Sales Account Manager listed as remote).
- **Cutting-edge tech**: Work with the latest sequencing technologies (Oxford Nanopore, PacBio, Illumina) and bioinformatics tools.
- **Culture**: Described as building "the world’s most efficient sequencing engine" with a focus on speed, simplicity, and scientific impact. Open roles include Senior Product Manager, Bioinformatics Scientist, Head of Logistics, Recruiter, and Customer Success Manager.
- **Headcount**: 110 employees with active hiring (7 open positions as of mid-2025); monthly headcount growth of -2.3% (likely seasonal fluctuation) but quarterly job postings up 75%.

## Sources
1. [plasmidsaurus.com](https://plasmidsaurus.com/)
2. [linkedin.com/company/plasmidsaurus](https://www.linkedin.com/company/plasmidsaurus)
3. [jobs.ashbyhq.com/plasmidsaurus](https://jobs.ashbyhq.com/plasmidsaurus)
4. [workinbiotech.com/companies/plasmidsaurus](https://workinbiotech.com/companies/plasmidsaurus)
5. [datanyze.com/companies/plasmidsaurus](https://www.datanyze.com/companies/plasmidsaurus/1316357043)

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