--- title: 'Senior Manager/Associate Director, Regulatory Affairs (Strategy, Hematology Oncology) at Nurix' canonical: 'https://feeny.ai/job/senior-manager-associate-director-regulatory-affairs-strategy-hematology-zsgdf1qycbew' type: 'job' last_seen: '2026-09-10' --- # Senior Manager/Associate Director, Regulatory Affairs (Strategy, Hematology Oncology) at Nurix - **Company:** Nurix - **Location:** Brisbane California, United States - **Posted:** 2026-09-07 - **Last confirmed live:** 2026-09-10 - **Apply:** https://job-boards.greenhouse.io/nurix/jobs/8785500002 ## Job description Senior Manager / Associate Director, Regulatory Affairs (Strategy, Hematology Oncology) Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease. Job Summary: In this role, you will be a core member of the Regulatory team and will be responsible for helping build and execute on global regulatory strategy, objectives, policies and programs pertaining to development and future marketing of products. Responsibilities: - Provides regulatory strategic direction and support for assigned global development programs/development program activities - Assists Sr. Regulatory Affairs staff with their development program activities and deliverables - Designs and implements regulatory strategies with Regulatory Affairs staff to obtain and maintain product investigative and marketing applications for assigned programs, as well as their life cycle management - Acts as regulatory representative on early and/or late phase clinical studies, ensuring compliant execution of trials - Strong competency in understanding regulatory requirements and emerging regulatory landscapes associated with US and global regulatory authorities - Experienced in responding to inquiries from global regulatory authorities as well as the preparation and conduct of meetings with global regulatory authorities - Assist in the preparation and maintenance of Annual Reports, Development Safety Update Reports (DSURs), Investigator’s Brochures and other documents required for INDs, CTAs, NDAs and other related regulatory development and marketing applications - Assist in the cataloging and maintenance of regulatory application submissions - Conduct research and stay up-to-date on regulatory requirements and changes - Collaborate with cross-functional teams to ensure product compliance throughout the development lifecycle - Monitor and assess regulatory risks and develop mitigation strategies - Oversee quality assurance processes to ensure compliance with regulatory standards - Review SOPs pertaining to Regulatory - Works strategically with all regulatory functions to develop detailed, actionable submission plans, tracks major submission deliverables, and ensures consistent management submission documents, health authority communications, and all other regulatory information supporting Nurix’s investigational and marketing applications - Plays an essential part in defining requirements for, implementing, and supporting future systems and tools to be employed by Nurix in the areas of document management, submission content planning, and regulatory information management - Tracks the status of major deliverables for regulatory submissions (e.g., study reports, summary documents, labeling) along with their dependencies - Develops and maintains submission plan templates to ensure Nurix regulatory submissions are consistently planned and executed across programs - Participates in cross-functional process initiatives impacting regulatory submission processes and systems - Manages consultants and contractors as needed Experience and Skills: - Bachelor's degree in life-sciences or related scientific discipline; advanced degree preferred Manager: - Must have minimum of 8 years in Regulatory affairs strategy - Strong demonstration of knowledge of drug development, FDA, EMA and ICH guidelines and regulations - Experience providing hands-on support for planning clinical trial and marketing applications to health authorities including but not limited to FDA, EMA - Ability to read, analyze and interpret scientific and technical information, as well as regulatory - Ability to understand and explain detailed regulatory affairs and compliance programs and/or to effectively present information to senior regulatory management, other departments or external - Ability to comply with changing regulatory - Proven track record of supporting Regulatory affairs in the planning and execution of major filings and ongoing maintenance of clinical trial and marketing applications - Strong project management and critical thinking skills - Experience applying project management techniques and tools (e.g., MS Project, Smartsheet, Excel trackers) to the planning and execution of regulatory submissions - Excellent organizational and communication skills, both written and verbal - Ability to work independently as well as part of a team environment - Positive attitude, energetic and proactive - Proven ability to manage multiple projects, identify and resolve regulatory issues - Strong interpersonal skills and the ability to effectively work with others Fit with Nurix Culture and Values - Strong team orientation; highly collaborative - Solutions and results-oriented focus - Hands-on approach; resourceful and open to diverse points of view Salary Range:   SM $187,800 - $208,638   AD $199,500 - $231,200 Location:          Brisbane, CA - Onsite ## About Nurix ## Company Overview - **One-liner**: Nurix Therapeutics is a clinical-stage biopharmaceutical company pioneering targeted protein degradation medicines to outmatch disease by harnessing the cell’s natural protein disposal system. - **Entity Type**: Public (NASDAQ: NRIX) - **Headquarters**: San Francisco, California, USA - **Founded**: 2009 - **Founders**: Not publicly listed as individual founders; the company was spun out from research at UC Berkeley and UC San Francisco. ## Core Business - **Primary industry**: Biopharmaceuticals / Targeted Protein Degradation - **Target customers**: B2B (pharma partners) and B2C (patients via clinical trials and eventual commercial therapies); enterprise-level partnerships with major pharma. - **Mission or purpose statement**: "Writing medicine’s next chapter using targeted protein degradation as a new script to outmatch disease." [nurixtx.com](https://www.nurixtx.com/) ## Products & Services - **Bexobrutideg (NX-5948)**: A potential best-in-class BTK degrader in Phase 1b/2 clinical trials for relapsed/refractory CLL/SLL and chronic spontaneous urticaria. Co-developed and co-commercialized with Roche under a global collaboration announced June 2026. [nurixtx.com](https://www.nurixtx.com/) - **NX-2127**: A BTK degrader in clinical development for B-cell malignancies. - **CBL-B Inhibitor (NX-1607)**: An E3 ligase inhibitor designed to activate T cells for immuno-oncology, in Phase 1 clinical trials. - **IRAK4 Degrader**: A partnered program with Gilead in Phase 1 for inflammatory diseases. - **STAT6 Degrader**: A partnered program with Sanofi in IND-enabling studies. - **DEL-AI Discovery Engine**: A proprietary, fully AI-integrated platform combining DNA-encoded libraries (DEL), automated chemistry, and machine learning to design and optimize targeted protein degraders and degrader-antibody conjugates (DACs). ## Market Standing - **Valuation/Market Cap**: Not publicly available in the provided search results; as a public company (NRIX), market cap fluctuates daily. Check financial platforms for the latest figure. - **Key Metric**: Annual Revenue (public) — Not publicly available in the provided search results; as a clinical-stage biotech, revenue is typically minimal or pre-revenue. Total funding raised prior to IPO is not detailed in the provided results. - **Notable Investors/Partners**: Roche (global co-development and co-commercialization collaboration for bexobrutideg, announced June 2026), Gilead (partnered IRAK4 degrader program), Sanofi (partnered STAT6 degrader program). - **Growth Signals**: Announced a landmark global collaboration with Roche in June 2026 to co-develop and co-commercialize bexobrutideg across malignant hematology, immunology, and neurology. Presented positive Phase 1a/b data for bexobrutideg in CLL/SLL and chronic spontaneous urticaria in 2026. Multiple partnered and wholly owned pipeline programs advancing through clinical and preclinical stages. ## Competitive Advantages - **Proprietary DEL-AI Discovery Engine**: A fully AI-integrated platform combining DNA-encoded libraries, automated chemistry, and machine learning to design degraders against any protein class, providing a significant speed and innovation advantage. [nurixtx.com](https://www.nurixtx.com/) - **Unparalleled Ligase Expertise**: Deep understanding of E3 ligase biochemistry and biology, a critical and complex component of the protein degradation mechanism, giving them a unique moat. - **Multi-Modal Pipeline**: Developing both small molecule degraders and Degrader-Antibody Conjugates (DACs), expanding the therapeutic reach and creating multiple shots on goal. - **Strong Partnership Network**: Collaborations with top-tier pharma (Roche, Gilead, Sanofi) validate their platform and provide non-dilutive funding and shared risk. ## Strategic Focus - **Clinical Advancement**: Driving lead asset bexobrutideg through pivotal trials in CLL/SLL and expanding into immunology (chronic spontaneous urticaria) and neurology. - **Platform Expansion**: Leveraging the DEL-AI engine to develop Degrader-Antibody Conjugates (DACs) for enhanced cell specificity and safety. - **Pipeline Breadth**: Advancing a multi-modal pipeline across oncology, immunology, and neurology, both wholly owned and through strategic partnerships. - **Partnership Leverage**: Deepening collaborations with Roche, Gilead, and Sanofi to co-develop and co-commercialize programs, reducing risk and accelerating timelines. ## Why Work Here - **Culture**: Mission-focused, values-based, and spirited culture emphasizing "breakthrough innovation," "leadership," "accountability," and "zealousness." Employees are encouraged to "think big and act bold." [nurixtx.com](https://www.nurixtx.com/work-at-nurix/) - **Work with Industry Leaders**: The team includes scientific innovators who built the protein degradation field, seasoned executives with biotech scaling expertise, and leading clinicians. [nurixtx.com](https://www.nurixtx.com/work-at-nurix/) - **Growth & Impact**: Employees can "wear many hats" and gain broad exposure in a lean, virtual drug developer environment. The company emphasizes career growth and opportunity-rich experiences. - **Work Policy**: Onsite in Brisbane, CA (San Francisco Bay Area) for most roles, as indicated by job postings. [nurixtx.com](https://www.nurixtx.com/explore-jobs/) - **Benefits**: Comprehensive health and welfare plans, enhanced parental leave, wellness reimbursement, 401(k) employer match, and a highly collaborative culture. [nurixtx.com](https://www.nurixtx.com/work-at-nurix/) - **Engineering/Science Culture**: Described as "mission-focused, values-based, and spirited," with a focus on "intellectual and technical ingenuity" and "intelligent risk-taking." The company is a "virtual drug developer" with a lean internal infrastructure, relying on SaaS and cloud platforms. [nurixtx.com](https://www.nurixtx.com/explore-jobs/) ## Sources 1. [nurixtx.com](https://www.nurixtx.com/) 2. [nurixtx.com](https://www.nurixtx.com/work-at-nurix/) 3. [nurixtx.com](https://www.nurixtx.com/explore-jobs/) 4. 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