---
title: 'Senior Manager, Commercial Supply Chain at Mirum Pharmaceuticals'
canonical: 'https://feeny.ai/job/senior-manager-commercial-supply-chain-mirum-pharmaceuticals-foster-city-ceg78r6809c2'
type: 'job'
last_seen: '2026-11-04'
---

# Senior Manager, Commercial Supply Chain at Mirum Pharmaceuticals

- **Company:** Mirum Pharmaceuticals
- **Location:** Foster City, CA
- **Posted:** 2026-10-30
- **Last confirmed live:** 2026-11-04
- **Apply:** https://job-boards.greenhouse.io/mirumpharmaceuticals/jobs/5278823007

## Job description

## MISSION

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.

## POSITION SUMMARY

Mirum Pharmaceuticals is seeking an experienced, highly motivated, and detail-oriented Senior Manager, Commercial Supply Chain to support its growing global commercial portfolio and new product launches.  This position will be primarily responsible for managing domestic and international commercial distribution, inventory management, and order-to-cash (O2C) operations to ensure timely, accurate, and compliant product delivery across global markets.  In addition, the role will support end-to-end (E2E) commercial supply planning activities, including demand and supply alignment, labeling and packaging coordination, and finished product supply execution, while developing the capabilities to provide effective planning backup and ensure business continuity.  The successful candidate will collaborate closely with cross-functional teams and external supply chain partners to drive operational excellence, maintain uninterrupted commercial supply, and support patient access.

## JOB FUNCTIONS/RESPONSIBILITIES

- Lead domestic and international commercial distribution operations to ensure timely, accurate, and compliant product delivery across global markets.
- Oversee order-to-cash (O2C) activities, including customer order management, inventory allocation, order fulfillment, shipment execution, and reconciliation in collaboration with Commercial Operations and Finance.
- Manage commercial finished goods inventory across North American 3PLs, ensuring inventory accuracy through regular reconciliation, product availability, timely replenishment, and effective shelf-life management.
- Manage relationships and operational performance of 3PLs, distributors, and logistics partners, including KPI development and monitoring, business reviews, and issue resolution.
- Support new product launches, market expansion, distribution network readiness, supplier qualification, and implementation of new distribution partners
- Collaborate with Quality and other cross-functional teams to ensure distribution compliance and support deviation investigations, change controls, CAPAs, and other quality-related activities, as applicable.
- Drive continuous improvement of distribution, inventory management, and O2C processes through standardized procedures, system enhancements, and operational efficiencies.
- Support E2E commercial supply planning activities, aligning demand, manufacturing, labeling and packaging, inventory, and distribution to ensure product availability.
- Collaborate with CMOs, CPOs, and cross-functional teams to monitor manufacturing and packaging schedules, component availability, finished product readiness, and supply execution.
- Support inventory projections, replenishment planning, supply-demand reconciliation, and proactive identification and mitigation of supply risks.
- Participate in commercial labeling and packaging planning, including packaging readiness, market-specific supply requirements, and new product introductions.
- Develop proficiency in E2E commercial planning processes, systems, and master data to provide effective backup support for supply planning and labeling and packaging activities.
- Support supply chain transitions, business continuity, and continuous improvement initiatives while staying informed of regulatory changes impacting commercial supply planning and distribution.

## QUALIFICATIONS

Education /Experience:

- Bachelor’s degree in Supply Chain Management, Business Administration, Operations Management, Logistics, or a related field.
- Minimum of 5-7 years of progressive experience in commercial supply chain, distribution, logistics, inventory management, or order-to-cash operations within the pharmaceutical or biotechnology industry.
- Demonstrated experience managing domestic and international commercial distribution operations, including third-party logistics (3PL) providers and external distribution partners.
- Strong understanding of order-to-cash processes, including customer order management, order fulfillment, inventory allocation, shipment execution, and reconciliation.
- Working knowledge of pharmaceutical Good Distribution Practices (GDP), Good Manufacturing Practices (GMP), and applicable regulatory and distribution requirements.
- Experience with international logistics, import/export requirements, customs clearance, Incoterms, and temperature-controlled pharmaceutical transportation.
- Experience collaborating with cross-functional teams, including Commercial Operations, Finance, Quality, Regulatory Affairs, and external supply chain partners.
- Demonstrated ability to independently manage complex operations, resolve supply chain issues, and drive process improvements.
- Experience managing contract manufacturing organizations (CMOs), contract packaging organizations (CPOs), and multiple global 3PLs.
- Knowledge of end-to-end commercial supply planning, including demand and supply planning, inventory projections, and supply-demand reconciliation.
- Experience supporting global pharmaceutical product launches and commercial supply chain expansion.
- Experience with advanced supply planning systems, such as Kinaxis RapidResponse, is preferred.
- ASCM CPIM certification is preferred.
- Demonstrated project management and negotiation skills, with experience supporting new product supply chain planning preferred.
- Familiarity with pharmaceutical serialization, track-and-trace, and market-specific distribution requirements.
- Experience establishing operational KPIs, conducting external partner business reviews, and leading continuous improvement initiatives.

Knowledge, Skills and Abilities:

- Strong organizational and time management skills, with exceptional attention to detail and the ability to manage multiple priorities and meet tight deadlines in a fast-paced environment.
- Excellent analytical, problem-solving, and decision-making skills, with the ability to proactively identify supply chain risks, resolve complex operational issues, and implement effective solutions.
- Strong communication, interpersonal, and cross-functional collaboration skills, with demonstrated ability to manage external partners and influence stakeholders without direct reporting authority.
- Demonstrated ability to work independently, take ownership of operational deliverables, and drive continuous improvement across commercial supply chain processes.
- Solid understanding of end-to-end commercial supply chain processes and the interdependencies between demand and supply planning, manufacturing, labeling and packaging, inventory management, and distribution.
- Ability and willingness to develop broader E2E commercial supply planning expertise, including systems and processes, to provide effective operational backup and ensure business continuity.
- Demonstrated integrity, accountability, adaptability, and a proactive, hands-on, team-oriented approach, with the ability to thrive in a small, dynamic organization.

The salary range for this position is $180,000 to $190,000 USD. Compensation will be determined based on several factors including, but not limited to; skill set, years of experience, and the employee’s geographic location. Please note that the required compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits unless otherwise provided.

## #LI-HYBRID

Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and to compliance with all Federal, State and Local laws that prohibit employment discrimination on the basis of race, age, national origin, ethnicity, religion, gender, gender identity, pregnancy, marital status, sexual orientation, citizenship, genetic disposition or characteristics, disability, veteran’s status or any other classification protected by applicable State/Federal/Local laws.

Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.

## About Mirum Pharmaceuticals

## Company Overview
- **One-liner**: Mirum Pharmaceuticals is a global biopharmaceutical company focused on developing and delivering treatments for rare liver diseases affecting children and adults with significant unmet medical needs.
- **Entity Type**: Public (NASDAQ: MIRM)
- **Headquarters**: Foster City, California, USA
- **Founded**: 2018
- **Founders**: Not publicly listed as individual founders; the company was established by a leadership team with deep rare disease and biotech experience who identified a deprioritized therapy for Alagille syndrome and moved decisively to advance it.

## Core Business
- **Primary industry/industries**: Biotechnology / Rare Disease Pharmaceuticals
- **Target customers**: Healthcare providers, patients, and families affected by rare liver diseases (Alagille syndrome, Progressive Familial Intrahepatic Cholestasis, and other cholestatic conditions); B2B relationships with payers, distributors, and healthcare systems globally.
- **Mission or purpose statement**: "Relentlessly Rare" — focused on conditions where the burden is profound and the need is greatest, combining deep expertise with disciplined execution to advance meaningful medicines for people around the world.

## Products & Services
- **LIVMARLI® (maralixibat)**: An oral, once-daily ileal bile acid transporter (IBAT) inhibitor approved for the treatment of cholestatic pruritus in Alagille syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC). Approved in multiple regions including the US and Europe. Additional development programs are underway.
- **Pipeline Programs**: A broad pipeline of investigational medicines targeting significant unmet needs in rare liver diseases, including additional indications for LIVMARLI and other early-stage programs.

## Market Standing
- **Valuation/Market Cap**: As of mid-2025, Mirum’s market capitalization is approximately $1.5–$2.0 billion (fluctuating with stock price; check current data on [ir.mirumpharma.com](https://ir.mirumpharma.com/overview/default.aspx)).
- **Key Metric**: Annual Revenue — Mirum generates revenue from commercial sales of LIVMARLI. In 2024, the company reported total revenue of approximately $290 million (preliminary figure; verify in latest 10-K). The company has transitioned from a development-stage to a commercial-stage biotech.
- **Notable Investors/Partners**: Public institutional investors; key partners include clinical sites, patient advocacy groups (e.g., Alagille Syndrome Alliance, PFIC Network), and global distribution partners for international markets.
- **Growth Signals**: Three approved medicines in its portfolio; global footprint with offices in North America and Europe; expanding pipeline with additional clinical programs; consistent revenue growth from LIVMARLI; growing commercial presence in Europe and other regions.

## Competitive Advantages
- **First-in-class / Best-in-class therapy**: LIVMARLI is the first and only approved treatment for cholestatic pruritus in Alagille syndrome, addressing a critical unmet need with no prior approved therapies.
- **Deep rare disease expertise**: The leadership team has extensive experience in rare disease drug development, regulatory strategy, and commercialization, allowing the company to navigate complex pathways efficiently.
- **Patient-centric culture**: Mirum embeds patient and family voices directly into development and commercial strategy, ensuring therapies meet real-world needs.
- **Disciplined execution**: The company was founded with a single deprioritized asset and rapidly advanced it to approval, demonstrating agility and focus.

## Strategic Focus
- **Expand global access**: Continuing to secure regulatory approvals and market access for LIVMARLI and other pipeline assets across North America, Europe, and other regions.
- **Advance pipeline**: Pursuing additional indications for LIVMARLI and developing new therapies for other rare liver diseases with high unmet need.
- **Deepen patient engagement**: Strengthening relationships with patient communities and advocacy groups to inform research, development, and commercialization.
- **Build commercial infrastructure**: Expanding commercial, medical affairs, and patient services teams globally to support growing product portfolio.

## Why Work Here
- **Mission-driven culture**: Mirum’s core values — "Care, Be Real, Get It Done, and Have Fun, Seriously" — foster a collaborative, high-performance environment where employees are empowered to bring their authentic selves to work.
- **Flexible work environment**: The company supports flexible ways of working, with offices in Foster City (global HQ), Basel (Switzerland), and Zug (Switzerland), plus US Remote roles available for certain positions. Arrangements vary by role.
- **Comprehensive benefits**: 100% employee medical premium coverage (with 100% dependent medical contributions), 4% 401(k) match with immediate vesting, 15% Employee Stock Purchase Plan, four weeks of PTO starting day one, company holidays including a winter shutdown, paid parental leave, up to $5,000 annual tuition reimbursement, and an Employee Assistance Program.
- **Collaborative community**: Regular "Coffee and Chats" and bi-weekly "Lunch Connections" foster cross-functional dialogue. Office environments are designed for connection with stocked snacks, beverages, and (in some locations) catered lunches and on-site baristas.
- **Growth opportunity**: As a high-growth public company with approved products and an expanding pipeline, employees have significant opportunities to contribute to meaningful milestones and career development.

## Sources
1. [mirumpharma.com](https://mirumpharma.com/)
2. [mirumpharma.com/about-us/our-story/](https://mirumpharma.com/about-us/our-story/)
3. [mirumpharma.com/jobs/](https://mirumpharma.com/jobs/)
4. [ir.mirumpharma.com](https://ir.mirumpharma.com/overview/default.aspx)
5. [job-boards.greenhouse.io/mirumpharmaceuticals](https://job-boards.greenhouse.io/mirumpharmaceuticals)

## Other roles at Mirum Pharmaceuticals

- [Therapeutic Account Manager, Liver - Seattle East](https://feeny.ai/job/therapeutic-account-manager-liver-seattle-east-mirum-pharmaceuticals-seattle-7g4gygec07re) — Seattle, WA
- [Regional Account Manager, Southeast - GEM](https://feeny.ai/job/regional-account-manager-southeast-gem-mirum-pharmaceuticals-miami-9rd41vp07fd5) — Miami, FL
- [Vice President, Program Leadership (Launch Products)](https://feeny.ai/job/vice-president-program-leadership-launch-products-mirum-pharmaceuticals-foster-ah28g7q6rnzr) — Foster City, CA
- [Executive Vice President, Head of International](https://feeny.ai/job/executive-vice-president-head-of-international-mirum-pharmaceuticals-foster-city-zks32xmse1bf) — Foster City, CA
- [Senior Manager, Program Management](https://feeny.ai/job/senior-manager-program-management-mirum-pharmaceuticals-foster-city-ca5ct930ztn6) — Foster City, CA
- [Senior Director, HR Business Partner](https://feeny.ai/job/senior-director-hr-business-partner-mirum-pharmaceuticals-foster-city-4hhwex05d1hc) — Foster City, CA
- [Director, Regulatory Project Management](https://feeny.ai/job/director-regulatory-project-management-mirum-pharmaceuticals-foster-city-4jg70n1k4q9c) — Foster City, CA
- [Director, Clinical Pharmacology](https://feeny.ai/job/director-clinical-pharmacology-mirum-pharmaceuticals-foster-city-hgkvgcbm9zz4) — Foster City, CA
- [Associate Director, Commercial Operations](https://feeny.ai/job/associate-director-commercial-operations-mirum-pharmaceuticals-zug-8badj97bpf21) — Zug, Switzerland
- [Therapeutic Account Manager, Liver - Baltimore](https://feeny.ai/job/therapeutic-account-manager-liver-baltimore-mirum-pharmaceuticals-baltimore-wsmckesc300t) — Baltimore, MD