---
title: 'Senior Manager, Medical Affairs Operations at BridgeBio Pharma'
canonical: 'https://feeny.ai/job/senior-manager-medical-affairs-operations-bridgebio-pharma-san-francisco-t05gjew4g5xx'
type: 'job'
last_seen: '2026-10-21'
---

# Senior Manager, Medical Affairs Operations at BridgeBio Pharma

- **Company:** BridgeBio Pharma
- **Location:** San Francisco, CA
- **Compensation:** $165k–$190k
- **Posted:** 2026-10-16
- **Last confirmed live:** 2026-10-21
- **Apply:** https://job-boards.greenhouse.io/bridgebio/jobs/5264700007

## Job description

Mavericks Wanted

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on

In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.

Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.

## What You'll Do

The Senior Manager, Medical Affairs Operations is the operational engine behind execution of the Medical Affairs Function (MAF) plan. This role owns the processes, timelines, tracking, and cross-functional coordination that allow medical strategy to be executed on time, on budget, and in compliance with company SOPs.

The core of the role is the interface between Medical Affairs and the budget, contracting, and procurement organization. This individual partners directly with cross-functional teams to ensure MAF activities are properly scoped, contracted, funded, tracked, and closed out. This spans MLR submissions, advisory boards, sponsorships, grants, congresses, and vendor engagements.

This position suits a highly organized project manager who is energized by making complex, multi-stakeholder plans happen.

## Key Responsibilities

- Serve as the primary Medical Affairs liaison to the budget, contracting, and procurement teams to ensure timely and compliant execution of all MAF activities
- Own contract workflow and logistical organization for advisory boards; this involves contract initiation, routing, fair market value documentation, execution, amendments, and close-out along with liaising with vendors for venue and technology needs.
- Coordinate the annual and quarterly MAF planning cycle, driving timelines, templates, inputs, and reviews to keep the process on schedule, spend to date, budget commitments
- Maintain the master MAF activity calendar, including sponsorship submission windows, contracting lead times, and congress sponsorship deadlines,
- Build and maintain a professional society sponsorship entitlement tracker maximizing sponsorship opportunities
- Coordinate logistics for meetings with society and organization leaders on behalf of medical leadership: scheduling, agendas
- Own congress operational execution: meeting room and workspace reservations, badge and registration management, and vendor coordination
- Liaise with scientific communications team to help manage production, shipment, tracking, and on-site delivery of medical and booth materials, with clear ownership of quantities, timelines, and approval status
- Serve as the operational point of contact with congress organizers, hotels, exhibit houses, AV vendors, and logistics providers
- Assist Medical Directors with MLR submissions — compiling submission packages, routing materials, tracking review status, monitoring turnaround times, and following up to keep materials moving

Where You’ll Work

This is either a hybrid role requiring in-office collaboration 2-3x per week in our San Francisco Office, or a U.S.-based remote role that will require quarterly, or as needed, visits to our San Francisco Office.

Travel up to 25% is expected for scientific congresses, advisory boards, company-sponsored symposia, KOL engagements, and key internal meetings.

## Who You Are

- Bachelor’s degree
- 5+ years of experience in Medical Affairs operations, medical or clinical program management, or a comparable operations role within pharmaceutical, biotech, or medical device
- Demonstrated experience managing budgets, forecasts, purchase orders, and vendor or contract administration in partnership with Finance and Legal
- Hands-on experience executing advisory boards, sponsorships, grants, or contracted service engagements from initiation through payment and close-out
- Proven congress or large-meeting logistics experience, including vendor management and materials coordination
- Experience supporting or coordinating medical/legal/regulatory review submissions
- Excellent project management skills with a track record of managing multiple concurrent workstreams
- Working knowledge of pharmaceutical compliance requirements (PhRMA Code, Sunshine Act, OIG guidance) as they apply to advisory boards, sponsorships, grants, and HCP engagements
- Excellent project management skills with the ability to manage multiple concurrent workstreams
- Strong cross-functional communication and stakeholder management skills, comfortable interacting with both internal leadership and external society representatives

## Preferred

- Experience in a rare disease, launch-stage, or high-growth biotech environment
- Experience building or scaling Medical Affairs operational infrastructure where processes did not previously exist
- Experience managing a sponsorship portfolio and tracking benefit realization
- Familiarity with contract lifecycle management and MLR review platforms

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

Salary $165,000—$190,000 USD

As a global company, our comprehensive benefits may vary based on location.  We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.

For BridgeBio Full-Time U.S Based Roles:

Financial & Rewards

- Market-leading compensation
- 401(k) with employer match
- Employee Stock Purchase Program (ESPP)
- Pre-tax commuter benefits (transit and parking)
- Referral bonus for hired candidates
- Subsidized lunch and parking on in-office days

Health & Well-Being

- 100% employer-paid medical, dental, and vision premiums for you and your dependents
- Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)
- Fertility & family-forming benefits
- Expanded mental health support (therapy and coaching resources)
- Hybrid work model with flexibility
- Flexible, “take-what-you-need” paid time off and company-paid holidays
- Comprehensive paid medical and parental leave to care for yourself and your family

Skill Development & Career Paths:

- People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
- We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching
- We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities

By applying, you acknowledge that BridgeBio will process your personal information as described in our [Global Candidate Privacy Notice](https://bridgebio.com/bridgebio-global-candidate-privacy-notice). Questions or requests: dataprivacy@bridgebio.com

## About BridgeBio Pharma

## Company Overview
- **One-liner**: BridgeBio Pharma develops transformative medicines for genetic conditions, using a decentralized hub-and-spoke model to accelerate drug development from early research to commercialization.
- **Entity Type**: Public (Nasdaq: BBIO)
- **Headquarters**: Palo Alto, California, USA (with hybrid offices in San Francisco, CA)
- **Founded**: Not explicitly stated in provided sources; the company references “over the past 10 years” as of 2026, suggesting founding around 2015–2016.
- **Founders**: Not publicly available from provided sources.

## Core Business
- **Primary industry**: Biotechnology / Genetic disease therapeutics
- **Target customers**: Patients living with genetic conditions, healthcare providers, payers, and academic research partners
- **Mission**: “To develop transformative medicines for genetic conditions” and “bridge the gap between advancements in genetic science and meaningful medicines for underserved patient populations.”

## Products & Services
BridgeBio’s pipeline includes both approved therapies and investigational candidates across dozens of indications. Key offerings:

- **Acoramidis**: Approved for transthyretin amyloidosis (ATTR) – a first-in-class treatment with $8B+ peak year sales potential.
- **Infigratinib**: Phase 3 completed for achondroplasia; published in the *New England Journal of Medicine* (2026).
- **BBP-418**: Investigational for Limb-Girdle Muscular Dystrophy Type 2I/R9 (LGMD2I/R9).
- **Encaleret**: Investigational for Autosomal Dominant Hypocalcemia Type 1 (ADH1).
- **BBP-812**: Investigational for Canavan Disease.
- **BridgeBio Oncology Therapeutics (BBOT)**: Subsidiary focused on RAS and PI3Kα-driven cancers.
- **GondolaBio**: Subsidiary developing bioavailable small molecule inhibitors for oncology.
- **Other programs**: Covering hypochondroplasia, chronic hypoparathyroidism, and more.

The company has received **3 FDA approvals** and has over **70+ peer-reviewed publications**.

## Market Standing
- **Valuation / Market Cap**: Not explicitly stated in provided data; as a public company, current market cap can be found on financial platforms (e.g., ~$8B based on peak sales potential, but not a direct valuation number).
- **Key Metric**: **3 FDA-approved medicines**; **2000+ patients enrolled** in global clinical trials; **6 Phase 3 trials** conducted over the past 10 years.
- **Notable Investors / Partners**: Not detailed in provided sources, but the company partners with leading academic institutions to advance early-stage research.
- **Growth Signals**: Recent publication of Phase 3 PROPEL 3 trial results in NEJM (June 2026); expansion into oncology via BBOT and GondolaBio; 100% of pipeline is first-in-class or best-in-class; 48 unique disease indications targeted.

## Competitive Advantages
- **Hub-and-spoke model**: Decentralized structure where autonomous affiliate teams (spokes) focus on specific conditions, while a central hub provides clinical, regulatory, and commercial expertise. This enables speed, scalability, and risk reduction.
- **First-in-class / best-in-class focus**: 100% of pipeline aims to be first or best in class, targeting underserved genetic conditions with clear biological rationale.
- **Speed and adaptability**: The model allows rapid pivoting to the most promising opportunities, reducing development timelines compared to traditional biotech.
- **Strong scientific foundation**: Over 70 peer-reviewed papers and collaborations with top academic institutions.

## Strategic Focus
- **Advance late-stage pipeline**: Prioritize Phase 3 programs (e.g., infigratinib for achondroplasia, acoramidis for ATTR) and seek additional FDA approvals.
- **Expand into oncology**: Leverage subsidiaries BBOT and GondolaBio to address RAS/PI3Kα-driven cancers.
- **Maintain urgency**: “Every minute counts” – continue to operate with speed and autonomy to bring treatments to patients faster.
- **Build on commercial success**: Leverage existing approved products to fund further R&D and expand global reach.

## Why Work Here
- **Award-winning culture**: Named **#1 Best Place to Work** by BioSpace (2026, small biotech category) with an **88% employee engagement score** in 2025.
- **Flexible work model**: Hybrid policy with offices in San Francisco and Palo Alto, CA; “flexible working model” emphasized.
- **Compensation and benefits**: Market-leading pay, comprehensive healthcare, and strong emphasis on growth and internal mobility.
- **Impact-driven mission**: Work on transformative treatments for genetic conditions where patient need is urgent – “Impatient for Patients” is a core mantra.
- **Values**: Put patients first, let science speak, think independently, speak up, and act with urgency. The culture is described as “high on standards, low on convention.”
- **Growth opportunities**: 113 open jobs (as of mid-2026) across functions including clinical, regulatory, manufacturing, commercial, and corporate; talent community available for future roles.

## Sources
1. [bridgebio.com](https://bridgebio.com/) – Home page with pipeline overview and $8B peak sales potential
2. [bridgebio.com/about](https://bridgebio.com/about) – Company description, hub-and-spoke model, and key metrics
3. [bridgebio.com/careers](https://bridgebio.com/careers) – Careers page with awards, culture, and benefits
4. [investor.bridgebio.com](https://investor.bridgebio.com/overview/default.aspx) – Investor relations overview, latest news, and corporate presentation
5. [job-boards.greenhouse.io/bridgebio](http://job-boards.greenhouse.io/bridgebio) – Current job listings (113 roles) and departmental categories

## Other roles at BridgeBio Pharma

- [Commercial Learning & Development, Associate Director](https://feeny.ai/job/commercial-learning-development-associate-director-bridgebio-pharma-san-trqgav8a5c7b) — San Francisco, CA
- [Principal Clinical Database Systems Programmer](https://feeny.ai/job/principal-clinical-database-systems-programmer-bridgebio-pharma-united-states-q01smtxf9bc3) — United States
- [Field Reimbursement Manager - Northern CA](https://feeny.ai/job/field-reimbursement-manager-northern-ca-bridgebio-pharma-united-states-th5wwrdfe4n0) — United States
- [Senior Director, Commercial, EU Center](https://feeny.ai/job/senior-director-commercial-eu-center-bridgebio-pharma-germany-4t6tncfrnpf0) — Germany
- [Field Reimburesement Manager - Pennsylvania](https://feeny.ai/job/field-reimburesement-manager-pennsylvania-bridgebio-pharma-united-states-h2c4mn5nf8fg) — United States
- [Field Reimbursement Manager - Michigan](https://feeny.ai/job/field-reimbursement-manager-michigan-bridgebio-pharma-united-states-6shtx6w6zc4w) — United States
- [Sr. Manager/Associate Director, Medical Affairs](https://feeny.ai/job/sr-manager-associate-director-medical-affairs-bridgebio-pharma-united-states-52dejpfy2e92) — United States
- [Field Reimbursement Manager-Southeast](https://feeny.ai/job/field-reimbursement-manager-southeast-bridgebio-pharma-united-states-9r2cmwtagmzc) — United States
- [Field Reimbursement Manager-Pacific](https://feeny.ai/job/field-reimbursement-manager-pacific-bridgebio-pharma-united-states-rzn1q25j1qes) — United States
- [Field Reimbursement Manager-Northeast](https://feeny.ai/job/field-reimbursement-manager-northeast-bridgebio-pharma-united-states-pw7vp013z0pf) — United States