---
title: 'Senior Manager, People & Culture Operations at Alumis'
canonical: 'https://feeny.ai/job/senior-manager-people-culture-operations-alumis-south-san-francisco-5h92h9gc4d8j'
type: 'job'
last_seen: '2026-09-15'
---

# Senior Manager, People & Culture Operations at Alumis

- **Company:** Alumis
- **Location:** South San Francisco, CA
- **Posted:** 2026-08-06
- **Last confirmed live:** 2026-09-15
- **Apply:** https://job-boards.greenhouse.io/alumis/jobs/5380299008

## Job description

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.

The Senior Manager, People & Culture Operations, will report to the Senior Director, People & Culture, to establish and maintain strong HR operational framework.  This position will manage the day-to-day input of the HRIS, offer process, onboarding and offboarding, as well as all operational excellence related to annual merit process, employee reward and recognition programs.

## Responsibilities

- Offer and Onboarding Process including New Hire Orientation
- Exit and Offboarding Process
- Daily maintenance of Alumis’ HRIS, supporting system enhancements, and ensuring efficient HR operations.
- Management of the employee reward and recognition programs and processes
- Administer mandatory employee training by tracking completion, maintaining records, issuing reminders, and ensuring compliance with federal, state, and company requirements.
- Manage and maintain employee swag inventory, fulfillment processes, and vendor coordination
- Identify opportunities for process improvements and automation to increase efficiency and scalability
- Process verifications of employment
- Maintain P&C SharePoint site
- Strong partnership with Total Rewards, HR Business Partners and Talent Acquisition teams
- Adhoc P&C team administrative support

Must Have Skills/Experience

- Bachelor’s Degree in related field.
- 7+ years’ experience in HR, HR operations, customer services
- Strong business and HR acumen.
- High level of discretion and ability to handle sensitive and confidential information.
- Exceptional attention to detail.
- Ability to manage multiple priorities and meet deadlines in a fast-paced environment.
- Ability to consistently meet or exceed goals and KPIs with excellence mind-set.
- Knowledge of large-scale data management, payroll, time and HRIS systems solutions and strong skills in technologies.
- Understanding of interactions between HR, accounting, and finance.
- Demonstrated ability to influence across teams and collaborate well with cross-functional partners.
- Strong analytical, problem-solving, planning, decision-making skills and process orientation.
- Experience in continuous improvement projects.
- Proficient in Microsoft Office applications, including Excel, Word, PowerPoint, and Outlook, as well as SharePoint

Nice-to-Have Skills/Experience

- Current/Previous HRIS experience (BambooHR)
- HR Policy experience
- Strong process and project management skills
- Ability to work within the gray
- Strong communication skills

This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.

The salary range for this position is $156,900 USD to $185,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.

Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.

Other benefits include:

- Health insurance premiums paid at 90% for employee, 80% for dependents
- Free access to Genentech Bus & Ferry Share program
- $100 monthly cell phone stipend
- Unlimited PTO for Exempt employees
- Free onsite gym and a kitchen stocked with yummy snacks and drinks!

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.

Alumis Inc. is an equal opportunity employer.

## About Alumis

## Company Overview
- **One-liner**: Alumis is a public biotechnology company pioneering precision-targeted therapies for immune-mediated diseases, with a late-stage pipeline and proprietary data analytics platform.
- **Entity Type**: Public (ticker symbol not confirmed in available sources; reports quarterly financials as a public company)
- **Headquarters**: South San Francisco, California, United States
- **Founded**: 2021
- **Founders**: Incubated by Foresite Labs; leadership includes Martin Babler (President, CEO and Chairman of the Board)

## Core Business
- **Primary industry**: Biotechnology – immune-mediated disease therapeutics.
- **Target customers**: Patients with immune-mediated diseases (e.g., psoriasis, lupus), physicians, and healthcare systems (B2B/B2C).
- **Mission statement**: Transform treatment for immune-mediated diseases, empower people to reimagine their lives.

## Products & Services
- **Envudeucitinib (oral TYK2 inhibitor)**: Late-stage candidate for plaque psoriasis; Phase 3 trials demonstrated early and robust improvements in skin clearance, quality of life, and psoriasis symptoms. Designed as a next-generation oral therapy.
- **Proprietary Data Analytics Platform**: Internal platform that integrates scientific insights to select the right target, molecule, indication, patient, and endpoint.
- **Pipeline of targeted therapies**: Additional programs for other immune-mediated diseases (specific indications not publicly detailed), all aiming to replace broad immunosuppression with precise treatments.

## Market Standing
- **Valuation/Market Cap**: Not disclosed in available sources.
- **Key Metric**: Total funding (private) not publicly available; as a public company, annual revenue is not yet disclosed (likely pre-revenue or early commercial stage).
- **Notable Investors/Partners**: Incubated by Foresite Labs; board includes members from Foresite Capital, Arvinas, and other biotech leadership.
- **Growth Signals**: 
  - Active late-stage Phase 3 trials with positive results for plaque psoriasis (March 2026).
  - Employee headcount of 246 (as of mid-2026), growing ~1.3% monthly.
  - 13 active job postings, up 30% in the month prior.
  - Listed job openings span Clinical Development, Commercial, Research & Technical Operations, and G&A.

## Competitive Advantages
- **Precision approach**: Proprietary data analytics platform enables smarter target selection and clinical trial design, reducing failure risk.
- **Late-stage portfolio**: Envudeucitinib already in Phase 3, targeting a large market (plaque psoriasis) with potential to become a leading oral therapy.
- **Experienced leadership**: Deep biotech expertise from CEO Martin Babler and a seasoned leadership team.
- **Focus on patient outcomes**: Differentiates from broad immunosuppressants by aiming for efficacy without life-limiting side effects.

## Strategic Focus
- Advance Envudeucitinib through regulatory approval and launch for plaque psoriasis.
- Expand pipeline into additional immune-mediated indications (rheumatology, lupus, etc.).
- Leverage data analytics to optimize clinical development and commercialization.
- Build commercial infrastructure (hiring VP of Medical Affairs, Director of Market Access, etc.).

## Why Work Here
- **Culture**: Emphasizes openness, collaboration, and respect; employee-led Culture Team drives engagement, growth, and inclusion.
- **Values**: Challenge conventional wisdom, nurture teammates, elevate each other.
- **Benefits**: Medical, dental, vision, 401k, unlimited time off, pet insurance, Employee Stock Purchase Plan, commuter benefits (including company-paid access to Genentech Bus and Ferry lines).
- **Work Environment**: Mostly based in South San Francisco; some roles offer remote flexibility (indicated as "United States" in job listings). Hybrid likely for local roles.
- **Growth**: High-performance, mission-driven environment with expanding headcount and pipeline; opportunity to impact transformative therapies.
- **Job Openings**: Currently hiring for senior scientific, clinical, commercial, and operational roles (Associate Director Biostatistics, Vice President Medical Affairs, Director Market Access, etc.).

## Sources
1. [alumis.com – Company Website](https://www.alumis.com/)
2. [alumis.com – Careers Page](https://www.alumis.com/careers/)
3. [alumis.com – About / Leadership](https://www.alumis.com/about/)
4. [alumis.com – Job Opportunities](https://www.alumis.com/careers/job-opportunities/)
5. [LinkedIn – Alumis Company Profile](https://www.linkedin.com/company/alumis-com)

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