--- title: 'Senior Manager, Vendor Management at Generate Biomedicines' canonical: 'https://feeny.ai/job/senior-manager-vendor-management-generate-biomedicines-remote-321ee8qrkrzj' type: 'job' last_seen: '2026-10-30' --- # Senior Manager, Vendor Management at Generate Biomedicines - **Company:** Generate Biomedicines - **Location:** Remote - **Compensation:** $140k–$185k - **Work type:** remote - **Posted:** 2026-10-29 - **Last confirmed live:** 2026-10-30 - **Apply:** https://generatebiomedicines.com/open-positions?gh_jid=4725357006 ## Job description The Role: We are seeking a Senior Manager to lead vendor oversight and internal coordination for our late-stage clinical program. This role will serve as a central point of coordination across external vendors and internal functions, helping ensure that work is aligned, timelines are integrated, dependencies are managed, and issues are addressed promptly. The Senior Manager will build strong working relationships with vendor teams and internal stakeholders, and will support effective alliance management across the program. The role requires a blend of clinical project management, vendor governance, and cross-functional coordination to keep complex, multi-vendor work moving toward program and study milestones. Here's how you will contribute: - Lead day-to-day oversight and coordination of vendors supporting the late-stage program, working with functional owners to track deliverables, timelines, risks, and performance. - Serve as a central coordination point across vendors and internal teams, helping clarify ownership, align activities, and resolve handoffs and dependencies. - Establish and maintain integrated program and vendor timelines, tracking milestones, critical-path activities, interdependencies, and changes that may affect delivery. - Coordinate cross-functional and vendor meetings, including agendas, pre-reads, decisions, action items, and follow-up. - Support the alliance management function by building effective working relationships, enabling clear communication, and helping resolve operational issues across company and vendor teams. - Partner with Clinical Operations, Clinical Data Management, Biostatistics, Regulatory, Safety, Quality, Finance, and other relevant functions to align vendor work with program needs. - Monitor vendor deliverables and service levels against agreed plans; identify gaps early and coordinate corrective actions with internal owners and vendor leads. - Maintain visibility of key risks, issues, decisions, assumptions, and dependencies; escalate matters requiring leadership attention with clear context and proposed next steps. - Support governance forums and program reviews by preparing concise status updates, dashboards, and recommendations. - Coordinate change control and scope updates with internal stakeholders and vendors, assessing impacts on timelines, resources, and study execution. - Promote consistent ways of working across vendors, including meeting cadence, reporting, escalation pathways, and documentation. - Contribute to continuous improvement by identifying coordination gaps, recurring issues, and opportunities to improve vendor collaboration and program delivery. The Ideal Candidate will have: - Bachelor’s degree in life sciences, business, project management, or a related field; advanced degree or project management certification is a plus. - 8+ years of experience in clinical operations, clinical project management, vendor management, or alliance management within the biopharmaceutical or clinical research industry. - 3+ years of experience managing late-stage clinical studies, clinical vendors, or complex cross-functional workstreams. - Experience coordinating vendors and cross-functional teams supporting late-stage clinical studies or complex development programs. - Demonstrated ability to manage integrated timelines, deliverables, dependencies, risks, and issues across multiple workstreams. - Familiarity with clinical trial operations and the roles of common clinical service providers, such as CROs, central laboratories, imaging providers, and technology vendors. - Experience facilitating vendor governance meetings and maintaining productive relationships across organizational boundaries. - Strong organizational and communication skills, including the ability to turn complex updates into clear status, decisions, and actions. - Sound judgment in identifying emerging risks, coordinating solutions, and escalating issues at the right time. - Ability to influence without direct authority and to work effectively with stakeholders at different levels. - Comfort working in a dynamic environment with competing priorities and changing program needs. Who Will Love This Job: The successful candidate is organized, collaborative, and accountable. They create clarity across teams, follow through on commitments, and build constructive relationships with vendors and internal partners. They can maintain a program-level view while staying close enough to operational details to spot coordination risks early and keep work progressing. ## About Generate Biomedicines We are a clinical-stage generative biology company pioneering the AI revolution in drug design and development. We are advancing a new approach to drug creation—one grounded in the ability to design proteins with defined biological intent. By integrating machine learning with large-scale experimentation, this approach aims to reduce the uncertainty, time, and cost associated with developing protein-based medicines. Founded in 2018, we are advancing a growing pipeline of clinical and preclinical programs across multiple disease areas and protein modalities. By unifying computational design and clinical development within a single operating model, we translate this approach into clinical-stage programs and are leading a shift from traditional drug discovery toward systematic drug generation. At Generate:Biomedicines, we collaborate across disciplines in new ways to invent and innovate. We bring diverse perspectives to a shared goal of delivering better medicines to patients in need, faster, guided by our values and leadership behaviors. Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Recruitment & Staffing Agencies: Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto. ## #LI-RT1 Compensation: The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package. Per Year Salary Range $140,000—$185,000 USD ## About Generate Biomedicines ## Company Overview - **One-liner**: Generate Biomedicines is a clinical-stage generative biology company pioneering the use of machine learning to design and develop protein-based medicines on demand. - **Entity Type**: Public (ticker: GBIO) - **Headquarters**: Somerville, Massachusetts, USA (Boynton Yards and Andover locations) - **Founded**: 2018 - **Founders**: Gevorg Grigoryan, Daria Hazuda, and others ## Core Business - **Primary industry**: Biotechnology / Drug Discovery & Development - **Target customers**: B2B (pharmaceutical partners) and patients (via clinical programs) - **Mission statement**: "We don’t discover medicines—we design them," with a belief that speed is a moral obligation to patients. ## Products & Services - **[Generate Platform™]**: An integrated computational and biohardware innovation stack that uses generative biology to design proteins with defined biological intent. It can generate up to a billion designed variants per cycle with cycle times as fast as ~8 days. - **[GB-0895 (Anti-TSLP Antibody)]**: A next-generation anti-TSLP monoclonal antibody for severe asthma and COPD, currently in global Phase 3 trials. Designed for ultra-high affinity (106 fM binding, 20x improvement over tezepelumab) and an extended half-life (98 days, longest known among TSLP-targeting therapies), enabling twice-yearly subcutaneous dosing. - **[GB-5267 (MUC-16 Armored CAR-T)]**: A cell therapy candidate for metastatic ovarian cancer, expected to enter Phase 1 in 1H26. - **[GB-4362 (Free MMAE Toxin Neutralizer)]**: A first-in-class neutralizer designed for combination with MMAE-based antibody-drug conjugates (ADCs), with Phase 1 initiation in bladder cancer expected 1H26. ## Market Standing - **Valuation/Market Cap**: Not publicly disclosed; IPO in February 2026 raised net proceeds of approximately $370 million. - **Key Metric**: $221.5 million cash balance at YE 2025, plus ~$370 million from IPO (early 2026). - **Notable Investors/Partners**: Strategic collaborations with Amgen, Novartis, MD Anderson Cancer Center, and Roswell Park Comprehensive Cancer Center. - **Growth Signals**: 5 clinical-stage programs enabled by the platform; initiated global Phase 3 studies for GB-0895; operating out of 140k+ square feet of lab and office space; has studied millions of proteins and generated 42,000 proteins built and tested. ## Competitive Advantages - **Fully integrated computational-biohardware loop**: Machine learning drives generative design, which feeds directly into high-throughput experimentation (including proprietary CryoEM with four of the best microscopes in the world), and results continuously train the AI system — a "living feedback loop" that compounds over time. - **Multimodal platform**: Can generate candidates across antibodies, CAR-T, and other protein modalities from a single core technology, enabling a pipeline that covers both immunology and oncology. - **Record speed and scale**: Capable of generating up to a billion designed variants in ~8-day cycles, dramatically reducing the time and cost traditionally associated with drug discovery. - **First-mover in next-gen anti-TSLP**: First known next-generation anti-TSLP antibody to enter the clinic (GB-0895) with a differentiated half-life profile that could enable twice-yearly dosing, a significant competitive edge in a large market. ## Strategic Focus - **Clinical execution**: Advancing GB-0895 through global Phase 3 trials in severe asthma (with data in 2H27/1H28) and initiating late-stage development in COPD. - **Pipeline expansion**: Moving GB-5267 (CAR-T) and GB-4362 (ADC neutralizer) into Phase 1 in 2026, expanding the platform's therapeutic scope. - **Platform scaling**: Continuing to refine the generative biology engine to unlock new modalities and therapeutic areas, while deepening existing strategic collaborations with major pharma partners. - **Organizational growth**: Building out the team across computational, wet-lab, clinical, and operational functions to support the growing pipeline. ## Why Work Here - **Mission-driven**: The company is explicit that "speed is not just a competitive advantage—it’s a moral obligation." Employees are directly involved in designing drugs rather than discovering them, with a focus on getting treatments to patients faster. - **Interdisciplinary culture**: The company emphasizes true integration across machine learning, biological engineering, and medicine. As stated on their site, "We are a close-knit group of cross-disciplinary experts... each conversant in one another’s fields, working together to create a new one." - **Cutting-edge technology**: Access to unique computational and biohardware infrastructure, including "the four best CryoEM microscopes in the world" and a high-throughput experimental loop that powers AI training in real-time. - **Values-driven leadership**: Explicit leadership behaviors include "value the knowledge we gain more than the knowledge we have," "bring creativity, tenacity, and ingenuity to every challenge," and "hold oneself and others to an obligation to dissent." - **Hybrid/office policy**: Not explicitly stated, but the company operates large physical facilities in Somerville and Andover, MA, and offers free parking, monthly subway passes, or subsidized commuter rail passes, suggesting a significant on-site expectation. - **Comprehensive benefits**: Competitive pay, employee stock option plan, health/vision/dental insurance, long- and short-term disability, life insurance, EAP, retirement savings, paid parental/adoption/caregiver leave, free weekly lunch, and stocked kitchen. - **Growth trajectory**: As a newly public company with a cash-rich balance sheet and multiple catalysts over the next 12–24 months, the company offers significant career growth potential for those who want to be part of building a "transcendent company" that redefines an industry. ## Sources 1. [generatebiomedicines.com](https://generatebiomedicines.com/) 2. [generatebiomedicines.com/careers](https://generatebiomedicines.com/careers) 3. [generatebiomedicines.com/about-us](https://generatebiomedicines.com/about-us) 4. [investors.generatebiomedicines.com](https://investors.generatebiomedicines.com/) 5. [Non-Confidential Overview (April 2026)](https://investors.generatebiomedicines.com/wp-content/uploads/2026/04/Generate-Biomedicines-Non-Confidential-Overview_April-2026-1.pdf) ## Other roles at Generate Biomedicines - [Senior Clinical Trial Manager](https://feeny.ai/job/senior-clinical-trial-manager-generate-biomedicines-remote-c0vrxewkybbt) - [Director, Clinical Procurement](https://feeny.ai/job/director-clinical-procurement-generate-biomedicines-remote-qakj30d4dthm) - [Senior Director, Clinical Operations Business & Excellence](https://feeny.ai/job/senior-director-clinical-operations-business-excellence-generate-biomedicines-42e1kvgmzdf6) - [Senior Scientist I, Computational Protein Design](https://feeny.ai/job/senior-scientist-i-computational-protein-design-generate-biomedicines-somerville-caa239jvj23x) — Somerville, MA - [Scientist I, Computational Protein Design](https://feeny.ai/job/scientist-i-computational-protein-design-generate-biomedicines-somerville-6n26sf6x6wva) — Somerville, MA - [Scientist II, Functional Bioassays & High Throughput Screening](https://feeny.ai/job/scientist-ii-functional-bioassays-high-throughput-screening-generate-ajjehf28b7v6) — Somerville, MA - [Senior Scientist I, Protein Analytics & Biophysics](https://feeny.ai/job/senior-scientist-i-protein-analytics-biophysics-generate-biomedicines-somerville-84zvsqcb2gzh) — Somerville, MA - [Principal Scientist, Target Binding](https://feeny.ai/job/principal-scientist-target-binding-generate-biomedicines-somerville-nst4sw7htmp7) — Somerville, MA - [Scientist I, Synthetic Biology](https://feeny.ai/job/scientist-i-synthetic-biology-generate-biomedicines-somerville-xfvg8ftyvq3y) — Somerville, MA - [Associate Director, Biotherapeutic Production and Characterization](https://feeny.ai/job/associate-director-biotherapeutic-production-and-characterization-generate-vhxshbh7baa1) — Somerville, MA