---
title: 'Senior Medical Science Liaison - Movement Disorders at Praxis Precision Medicines, Inc.'
canonical: 'https://feeny.ai/job/senior-medical-science-liaison-movement-disorders-praxis-precision-medicines-6mw00pf2a0c0'
type: 'job'
last_seen: '2026-09-13'
---

# Senior Medical Science Liaison - Movement Disorders at Praxis Precision Medicines, Inc. 

- **Company:** Praxis Precision Medicines, Inc. 
- **Location:** United States
- **Compensation:** $190k–$220k
- **Work type:** remote
- **Posted:** 2026-07-31
- **Last confirmed live:** 2026-09-13
- **Apply:** https://job-boards.greenhouse.io/praxisprecisionmedicines/jobs/5376589008

## Job description

Location:  This position is field-based and will require up to 80% travel.

The Opportunity

Praxis is seeking a field-based Senior Medical Science Liaison (Senior MSL) to support Medical Affairs activities for ulixacaltimide during prelaunch and potential launch. This role is focused on building trusted scientific partnerships, delivering high-quality scientific exchange, and generating actionable insights to inform medical strategy and ensure clinical readiness. You will provide coaching, guidance, and peer leadership to other MSLs while also maintaining strategic engagement with key investigators, movement disorder specialists, and other neurology stakeholders.

This individual will play a critical role in translating medical strategy into field execution, ensuring high-quality scientific exchange, and driving clinical and account readiness in advance of and following potential approval. The role requires strategic thinking and field engagement, serving as a field-based scientific leader and trusted resource to the broader MSL team.

Given the significant unmet need in essential tremor and the opportunity to introduce a novel therapeutic option, this role will help shape disease education, stakeholder engagement, and the evolving treatment paradigm across both academic and community neurology settings.

Success in this role requires strong clinical credibility, excellent communication skills, strategic thinking, and comfort operating autonomously in a fast-paced environment.

Primary Responsibilities

Field Strategy & Execution

- Translate medical strategy into a clear, executable field plan aligned with pre-launch and launch priorities
- Contribute to territory planning, KOL identification, and stakeholder engagement strategies across regions
- Ensure consistent, high-quality scientific exchange across the team, including disease state education and product data communication
- Support clinical and account readiness efforts, including site preparedness, patient identification, and integration into clinical practice
- Monitor field activity and adapt strategy based on evolving insights and market dynamics
- Support territory alignment and resource deployment strategies to ensure optimal coverage of key accounts and stakeholders
- Support the evolution of field medical strategy across the product lifecycle, from pre-launch readiness through post-launch adoption and expansion

KOL Engagement & Scientific Leadership

- Maintain direct relationships with key national and regional KOLs, investigators, and thought leaders
- Lead high-impact scientific engagements, including advisory boards, congress interactions, and complex clinical discussions
- Serve as a scientific leader within the organization, ensuring credibility and consistency in external interactions
- Support the identification and development of emerging influencers and strategic partnerships

Insight Generation & Cross-Functional Collaboration

- Oversee the collection, synthesis, and communication of field insights to inform medical and cross-functional strategy
- Partner closely with Clinical Development, Commercial, and Market Access to ensure alignment and effective execution
- Translate field insights into actionable recommendations that shape launch strategy, evidence generation, and stakeholder engagement
- Contribute to the development of medical materials, training, and strategic initiatives as needed
- Represent the voice of the external medical community by translating field insights into strategic recommendations that inform medical and cross-functional decision-making

## Qualifications and Key Success Factors

- Advanced clinical or scientific degree (PharmD, PhD, MD, NP, PA, or RN)
- Experience in medical affairs, clinical research, clinical care, or field-based roles within biotech/pharma
- Demonstrated ability to interpret, communicate, and translate complex scientific and clinical data into clear, actionable insights for diverse stakeholders
- Strong ownership mindset with the ability to operate independently, navigate ambiguity, and drive impact in a dynamic pre-launch/launch environment
- Proven ability to build and maintain trusted relationships with healthcare professionals, including investigators and key opinion leaders
- Experience gathering, synthesizing, and translating field insights into actionable recommendations for cross-functional teams
- Ability to manage multiple priorities with strong organizational skills, attention to detail, and consistent follow-through
- Willingness and ability to travel extensively (60–80%) in a field-based role
- Demonstrated experience leading, coaching field-based teams
- Proven ability to translate medical strategy into effective field execution and operational plans
- Experience influencing cross-functional stakeholders and aligning teams in a matrixed environment
- Experience in neurology, CNS disorders or movement disorders is preferred
- Experience within market access/payor landscape is preferred
- Demonstrated ability to rapidly develop expertise in new therapeutic areas and apply insights to field strategy
- Candidates with prior field-based experience and a demonstrated track record of independently driving scientific engagement, shaping clinical perspectives, and contributing to successful pre-launch and launch activities will be considered at a higher level

The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement.  You'll need comfort with screen work, basic hand coordination, and focus.  Reasonable accommodations may be made to enable individuals with disabilities to perform these functions. Annualized Base Salary $190,000—$220,000 USD

## Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans.  We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together!

Company Overview

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.  At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders.  Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Attention: Job Scam Alert Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

## About Praxis Precision Medicines, Inc. 

## Company Overview
- **One-liner**: Praxis Precision Medicines is a fully integrated, clinical-stage biopharmaceutical company developing precision therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance.
- **Entity Type**: Public (NASDAQ: PRAX)
- **Headquarters**: Boston, Massachusetts, United States
- **Founded**: 2015
- **Founders**: Dr. Steven Petrou (Co-Founder and President of R&D)

## Core Business
- **Primary Industry**: Biotechnology (CNS / Neuroscience)
- **Target Customers**: Patients with rare and prevalent neurological disorders (e.g., essential tremor, developmental and epileptic encephalopathies, focal epilepsy); healthcare providers; payers.
- **Mission / Purpose**: To translate genetic insights into the development of life-altering therapies for CNS disorders more effectively and efficiently.

## Products & Services
Praxis operates two proprietary platforms and a pipeline of late-stage and early-stage programs:
- **Cerebrum™ (Small Molecule Platform)**: Orally available precision therapies targeting ion channels and neuronal circuits. Key assets include:
    - **Ulixacaltamide**: A T-type calcium channel inhibitor for essential tremor (ET). NDA submission to the FDA expected by mid-February 2026. Breakthrough Therapy Designation.
    - **Relutrigine**: For SCN2A- and SCN8A-developmental and epileptic encephalopathies (DEEs). NDA submission expected by mid-February 2026. Breakthrough Therapy Designation. Also in Phase 3 for broad DEEs.
    - **Vormatrigine**: A sodium-channel modulator for focal onset seizures (FOS). In Phase 3 trials (POWER1, POWER2).
- **Solidus™ (Antisense Oligonucleotide Platform)**: For genetically defined CNS disorders. Key asset:
    - **Elsunersen**: An ASO designed to reduce SCN2A gene expression for early-seizure-onset SCN2A-DEE. In Phase 3 (EMBRAVE3). Orphan Drug Designation.
- **Early-Stage Pipeline**: Preclinical candidates (PRAX-020, PRAX-080, PRAX-090, PRAX-100) targeting other genetic epilepsies and neurodevelopmental disorders.

## Market Standing
- **Market Cap**: ~$156.0 million (as of mid-2026 data) [linkedin.com]
- **Key Metric (Revenue/Funding)**: Annual revenue reported at ~$8.6M (pre-commercial stage). Pro forma cash, cash equivalents, and marketable securities stand at **$1.5 billion** following a public offering in January 2026 that raised ~$621 million [ir.praxismedicines.com].
- **Notable Investors/Partners**: Ionis Pharmaceuticals, Inc. (collaboration on elsunersen); RogCon, Inc. (license agreement).
- **Growth Signals**:
    - Rapidly scaling headcount: 166 employees (+49.7% year-over-year) [linkedin.com].
    - Transformation to a commercial-stage company: Preparing for two NDA submissions by mid-February 2026.
    - Combined peak revenue estimates for its four late-stage assets expected to exceed **$20 billion** [ir.praxismedicines.com].
    - Active hiring: 31 open positions in mid-2026 (up 933% year-over-year) [linkedin.com].

## Competitive Advantages
- **Precision Neuroscience Moat**: Deep understanding of shared biological targets and circuits in the brain derived from genetic epilepsies.
- **Proprietary Dual Platforms**: Leveraging both small molecule (Cerebrum) and ASO (Solidus) modalities to address a wide range of CNS disorders.
- **Breakthrough Therapy Designations**: Both lead assets (ulixacaltamide, relutrigine) have FDA Breakthrough Therapy Designation, accelerating development and review.
- **Strong Cash Position**: $1.5 billion pro forma cash provides a long runway through multiple potential product launches and pipeline expansion.
- **Late-Stage Pipeline**: Four late-stage product candidates approaching potential commercial launch, de-risking the company substantially.

## Strategic Focus
- **Commercial Launch Readiness**: Building out commercial infrastructure, sales force, and patient support programs in parallel with regulatory submissions.
- **Pipeline Expansion**: Declaring multiple new drug candidates from both Cerebrum and Solidus platforms in 2026.
- **Lifecycle Management**: Exploring indication expansion for existing assets (e.g., relutrigine in broad DEEs via the EMERALD study; vormatrigine for monotherapy FOS).
- **Global Reach**: Operating in 5 countries (US, Australia, India, Colombia, Brazil) with a growing workforce.

## Why Work Here
- **Mission-Driven Work**: Opportunity to deliver transformative therapies to patients with severe, underserved CNS disorders.
- **Growth Trajectory**: The company is at a pivotal inflection point, transitioning from a clinical-stage to a commercial-stage organization — offering dynamic career growth.
- **Remote-First Culture**: The vast majority of open positions across all departments (Clinical, Medical, Commercial, Finance, Legal, etc.) are listed as **"United States - Remote"** [greenhouse.io]. This includes roles like Director, Commercial Compliance; Senior Clinical Trial Manager; and Director, Field Reimbursement.
- **Global Talent**: Engineering and technical roles are open internationally (e.g., Software Engineer in Brazil) [greenhouse.io].
- **Strong Leadership**: Recent appointments of experienced pharmaceutical executives (Jeffrey B. Kinder, Stuart Arbuckle) and internal promotions (Megan Sniecinski to COO).
- **Compensation**: Employee reviews indicate a strong **Compensation rating of 4.0/5.0**, though overall culture and career ratings are lower (2.8 and 2.7 respectively on LinkedIn) [linkedin.com].
- **Workforce Demographics**: A high proportion of Director-level roles are open (20% of workforce), alongside specialists and senior IC roles, suggesting significant opportunities for leadership-level hires.

## Sources
1. [greenhouse.io](http://job-boards.greenhouse.io/praxisprecisionmedicines) - Jobs at Praxis Precision Medicines, Inc.
2. [ir.praxismedicines.com](https://ir.praxismedicines.com/news-releases/news-release-details/praxis-precision-medicines-enters-its-next-chapter-following) - Press Release: Business Outlook and Priorities for 2026
3. [linkedin.com](https://www.linkedin.com/company/praxis-precision-medicines-inc) - LinkedIn Company Profile
4. [stockanalysis.com](https://stockanalysis.com/stocks/prax/company/) - Company Profile & Key Executives

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