---
title: 'Senior Medical Science Manager North UK at Ultragenyx Pharmaceutical'
canonical: 'https://feeny.ai/job/senior-medical-science-manager-north-uk-ultragenyx-pharmaceutical-united-kingdom-rd4ajn23t7z4'
type: 'job'
last_seen: '2026-11-09'
---

# Senior Medical Science Manager North UK at Ultragenyx Pharmaceutical

- **Company:** Ultragenyx Pharmaceutical
- **Location:** United Kingdom
- **Work type:** remote
- **Posted:** 2026-10-15
- **Last confirmed live:** 2026-11-09
- **Apply:** https://job-boards.greenhouse.io/ultragenyxpharmaceutical/jobs/4739806005?gh_jid=4739806005

## Job description

Why Join Us?

Be a hero for our rare disease patients

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultraimpact – Make a difference for those who need it most

As Senior Medical Science Manager (Sr. MSM) you are responsible for developing and enhancing professional relationships with medical thought leaders involved in various phases of product development, as well as key medical organisations including treatment centres of excellence and established societies and associations in the UK. You provide medical information through scientific exchange in a fair balanced manner and provide clinical/scientific support to the company. These are field-based services and require professionals with established personal and scientific credibility to interact with thought leaders and centres of excellence. You will support Ultragenyx products in development and commercialised brands in the UK.

Work Model:

Field: Officially documented as working as a member of the Ultragenyx field team, generally interacting with third parties on behalf of Ultragenyx.

Responsibilities:

- Key Opinion Leaders (KOLs) engagement and management: identify, establish, and maintain scientific relationships with KOLs; connecting to KOL in academic and community centres
- Uncover KOL insights on existing or emerging science with the potential to impact patient care
- Act as primary liaison to HCPs interested in developing projects with Ultragenyx, explore medical practices and specificities, and share with the local team
- Support the local ISTs and CUs follow-up
- Contribute to the elaboration of the local medical affairs plan with the Medical Affairs Director, and execute the plan - in alignment with regional and national plans
- Perform activities to increase awareness of the rare diseases of Ultragenyx interest
- Provide medical information in response to unsolicited questions in academic, community, and healthcare provider settings
- Provide clinical presentations, information updates, scientific support at medical congresses or for any appropriate educational initiatives
- Collaborate with the Clinical Operations team to support our clinical development program and the team locally (e.g., in identifying appropriate clinical trial sites, in connecting with investigators in ongoing studies…), if required
- Ensure “local” literature review on a regular basis; summarise key messages for internal use
- Contribute to the medical training of the local sales team and bring medical support as needed
- Works autonomously to organise and prioritise one’s own work schedule
- Accountable for individual territory management
- Proactively and consistently delivers on commitments, prioritises time, actions, and resources to meet goals despite obstacles and setbacks
- Participation in regular meetings with the Manager and local team
- Ensure all activities are compliant with company policies and SOPs

Requirements:

- Advanced degree in a clinical or medical specialty (MD, PhD, PharmD, Master of Science Degree) and relevant clinical experience preferred
- 3-5 years of experience in pharmaceutical industry in medical affairs required, and scientific expertise in rare disease is preferred
- Good understanding of the health care delivery system and patient pathway in the country
- Languages: Fluent in English
- Location: UK
- Approximately 50-60% travel is required; overnight travel can be required as needed

#LI-CK1 #LI-Remote

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

- Generous vacation time and public holidays observed by the company
- Volunteer days
- Long term incentive and Employee stock purchase plans or equivalent offerings
- Employee wellbeing benefits
- Fitness reimbursement
- Tuition sponsoring
- Professional development plans
- Benefits vary by region and country

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com.

See our [CCPA Employee and Applicant Privacy Notice](https://www.ultragenyx.com/CCPA-Notice/).

See our [Privacy Policy](https://www.ultragenyx.com/privacy-policy/).

Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation.  Inquiries on developing a recruiting relationship with us, may be directed to: [talentacquisition@ultragenyx.com](http://mailto:talentacquisition@ultragenyx.com/).

## About Ultragenyx Pharmaceutical

## Company Overview
- **One-liner**: Ultragenyx Pharmaceutical is a biopharmaceutical company dedicated to developing and commercializing first-ever treatments for rare and ultra-rare genetic diseases with high unmet medical need.
- **Entity Type**: Public (NASDAQ: RARE)
- **Headquarters**: Novato, California, United States
- **Founded**: 2010
- **Founders**: Emil D. Kakkis, M.D., Ph.D.

## Core Business
- **Primary industry/industries**: Biotechnology research; rare disease therapeutics (metabolic, bone, endocrine, muscle, and central nervous system disorders).
- **Target customers**: B2B (healthcare providers, payers, government agencies) and B2C (patients and patient advocacy groups).
- **Mission or purpose statement**: “Transform the lives of those living with rare diseases” (ultragenyx.com).

## Products & Services
- **Crysvita (burosumab)**: Approved for X-linked hypophosphatemia (XLH) – a biologic therapy.
- **Dojolvi (triheptanoin)**: Approved for long-chain fatty acid oxidation disorders (LC-FAOD) – a small molecule.
- **Mepsevii (vestronidase alfa)**: Approved for mucopolysaccharidosis VII (Sly syndrome) – an enzyme replacement therapy.
- **Evinacumab-dgnb (non-U.S. rights)**: Approved by FDA and EMA for homozygous familial hypercholesterolemia; marketed outside the U.S. under a partnership with Regeneron.
- **Pipeline**: A diverse portfolio across multiple modalities – gene therapies, antisense oligonucleotides (ASOs), mRNA therapies – targeting ultra-rare diseases in bone, endocrine, metabolic, muscle, and CNS categories (ultragenyx.com).

## Market Standing
- **Valuation/Market Cap**: ~$3.3 billion (as of June 2026, per LinkedIn company page and market data).
- **Key Metric**: Annual revenue of $673 million (most recent fiscal year); total funding of $1.55 billion (including Series A, post-IPO equity, and debt).
- **Notable Investors/Partners**:
  - Investors: Ontario Municipal Employees Retirement System (led $400M post-IPO debt in 2025), multiple venture and institutional investors.
  - Partners: Kyowa Hakko Kirin, Daiichi Sankyo, Mereo BioPharma, Regeneron (non-U.S. commercial rights for evinacumab).
- **Growth Signals**:
  - One of the largest and most diverse pipelines in rare disease.
  - Awarded “Best Place to Work” by BioSpace (2020, 2021) and recognized by Deloitte’s Fast 500.
  - Active job postings: 21 openings as of mid-2026 (LinkedIn), though headcount declined 1.9% YoY to 1,247 employees.
  - Recent news: Ultragenyx Reports Inducement Grant Under Nasdaq Listing Rule 5 (June 2026).

## Competitive Advantages
- **Ultra-rare focus**: Targets diseases with no approved therapies, creating first-ever treatments and building significant regulatory and commercial expertise.
- **Multi-modality platform**: Expertise across biologics, small molecules, gene therapies, ASOs, and mRNA – reducing risk and expanding addressable disease space.
- **Global infrastructure**: Operations in 20 countries (including Brazil, Switzerland, Mexico, Japan) and commercial presence in North America, Europe, Latin America, and Asia.

## Strategic Focus
- **Commercial expansion**: Hiring for Commercial and Medical Affairs teams to support growing product portfolio.
- **Gene therapy manufacturing**: Building a new gene therapy manufacturing facility in the Boston area to scale production for pipeline candidates.
- **Pipeline advancement**: Continued clinical development of gene therapies, ASOs, and mRNA programs for ultra-rare indications.

## Why Work Here
- **Culture**: Described as “inclusive, generous, curious, and humble,” with a strong emphasis on purpose and patient impact. Named a top workplace by BioSpace and Deloitte.
- **Benefits**: Comprehensive coverage starting on day one for all regular full-time employees; includes robust health, retirement, and wellness programs.
- **Work environment**: Hybrid/office model with multiple U.S. hubs (Novato, Brisbane, Boston area) and international offices. Employer rating on LinkedIn: 3.3/5 (324 reviews) with culture rated 3.5, compensation 4.0, and work-life balance 3.2.
- **Career development**: Internships, seasonal co-ops, and postdoctoral programs; strong alumni pipeline to top biopharma companies (Genentech, BioMarin, Vertex, Amgen).

## Sources
1. [ultragenyx.com](https://www.ultragenyx.com/)
2. [ultragenyx.com – Join Our Team](https://www.ultragenyx.com/join-our-team/)
3. [ultragenyx.com – Current Opportunities](https://www.ultragenyx.com/join-our-team/current-opportunities/)
4. [LinkedIn Company Page](https://www.linkedin.com/company/ultragenyx)
5. [talent.ultragenyx.com](https://talent.ultragenyx.com/)
6. [Greenhouse Careers Page](https://job-boards.greenhouse.io/ultragenyxpharmaceutical)

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