---
title: 'Senior Medical Science Manager at Ultragenyx Pharmaceutical'
canonical: 'https://feeny.ai/job/senior-medical-science-manager-ultragenyx-pharmaceutical-paris-ag112d1v24xj'
type: 'job'
last_seen: '2026-09-14'
---

# Senior Medical Science Manager at Ultragenyx Pharmaceutical

- **Company:** Ultragenyx Pharmaceutical
- **Location:** Paris, France
- **Posted:** 2026-08-06
- **Last confirmed live:** 2026-09-14
- **Apply:** https://job-boards.greenhouse.io/ultragenyxpharmaceutical/jobs/4719468005?gh_jid=4719468005

## Job description

Why Join Us?

Be a hero for our rare disease patients

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultrafocused – Work together to fearlessly uncover new possibilities

As Senior Medical Science Manager (Sr. MSM) in France, you cooperate closely with our field-based team and other relevant medical colleagues. You are responsible for developing and enhancing professional relationships with medical thought leaders involved in various phases of product development, as well as key medical organizations including treatment centers of excellence and established societies and associations in France. You provide medical information through scientific exchange in a fair balanced manner and provide clinical/scientific support to the company. Your services are field-based, and you possess established professional personal and scientific credibility to interact with thought leaders and centers of excellence. You will support Ultragenyx commercialized products and pipeline in France as your primary responsibility.

Work Model:

Field: Officially documented as working as a member of the Ultragenyx field team, generally interacting with third parties on behalf of Ultragenyx.

Responsibilities:

- Build and maintain strong scientific relationships with KOLs, HCPs, and diagnostic networks to enhance disease awareness and patient identification.
- Serve as a trusted medical partner by providing balanced scientific exchange and supporting investigator-initiated research.
- Capture and communicate emerging clinical and scientific insights to inform internal decision-making and strategy.
- Apply deep knowledge of rare diseases, particularly metabolic and genetic disorders, to guide medical engagement and education.
- Leverage advanced clinical training (MD, PhD, PharmD) and strong understanding of the healthcare system to provide local thought leadership.
- Contribute to local Market Access and pricing/reimbursement discussions with scientific expertise.
- Develop and implement territory plans aligned with regional and national strategies to support Ultragenyx’s medical objectives.
- Collaborate with field-based and global medical affairs colleagues, as well as cross-functionally, to drive the successful execution of scientific initiatives.
- Partner with Clinical Operations to identify trial sites, support patient recruitment, and foster productive relationships with investigators.
- Act as a key contact for HCPs pursuing investigator-initiated research opportunities.
- Deliver high-quality scientific and clinical presentations in diverse healthcare settings and contribute to medical education initiatives.
- Provide accurate, timely medical information and updates.
- Represent Ultragenyx at scientific meetings, congresses, and symposia through presentations, discussions, and scientific support.
- Provide expert engagement at advisory boards and contribute to shaping scientific dialogue with external stakeholders.

Requirements:

- Advanced degree in clinical specialty required (MD, PhD, PharmD) and commensurate experience
- Required: 3-5 years of industry experience
- Rare disease experience is preferred, particularly in neurology and metabolic and genetic disorders
- Demonstrated experience effectively presenting clinical/scientific information required
- Expert understanding of the health care delivery system and its impact on patient pathway in France
- Highly motivated; demonstrates resilience and flexibility; effective listening skills; excellent communication and presentation skills; works autonomously to organize and prioritize one’s own work schedule; proactively and consistently delivers on commitments
- Languages: Fluent in French and English
- Approximately 50-60% of travel is required; overnight travel is required as needed
- Valid driver’s license

#LI-CT1  #LI-Remote

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

- Generous vacation time and public holidays observed by the company
- Volunteer days
- Long term incentive and Employee stock purchase plans or equivalent offerings
- Employee wellbeing benefits
- Fitness reimbursement
- Tuition sponsoring
- Professional development plans
- Benefits vary by region and country

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com.

See our [CCPA Employee and Applicant Privacy Notice](https://www.ultragenyx.com/CCPA-Notice/).

See our [Privacy Policy](https://www.ultragenyx.com/privacy-policy/).

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation.  Inquiries on developing a recruiting relationship with us, may be directed to: [talentacquisition@ultragenyx.com](http://mailto:talentacquisition@ultragenyx.com/).

## About Ultragenyx Pharmaceutical

## Company Overview
- **One-liner**: Ultragenyx Pharmaceutical is a biopharmaceutical company dedicated to developing and commercializing first-ever treatments for rare and ultra-rare genetic diseases with high unmet medical need.
- **Entity Type**: Public (NASDAQ: RARE)
- **Headquarters**: Novato, California, United States
- **Founded**: 2010
- **Founders**: Emil D. Kakkis, M.D., Ph.D.

## Core Business
- **Primary industry/industries**: Biotechnology research; rare disease therapeutics (metabolic, bone, endocrine, muscle, and central nervous system disorders).
- **Target customers**: B2B (healthcare providers, payers, government agencies) and B2C (patients and patient advocacy groups).
- **Mission or purpose statement**: “Transform the lives of those living with rare diseases” (ultragenyx.com).

## Products & Services
- **Crysvita (burosumab)**: Approved for X-linked hypophosphatemia (XLH) – a biologic therapy.
- **Dojolvi (triheptanoin)**: Approved for long-chain fatty acid oxidation disorders (LC-FAOD) – a small molecule.
- **Mepsevii (vestronidase alfa)**: Approved for mucopolysaccharidosis VII (Sly syndrome) – an enzyme replacement therapy.
- **Evinacumab-dgnb (non-U.S. rights)**: Approved by FDA and EMA for homozygous familial hypercholesterolemia; marketed outside the U.S. under a partnership with Regeneron.
- **Pipeline**: A diverse portfolio across multiple modalities – gene therapies, antisense oligonucleotides (ASOs), mRNA therapies – targeting ultra-rare diseases in bone, endocrine, metabolic, muscle, and CNS categories (ultragenyx.com).

## Market Standing
- **Valuation/Market Cap**: ~$3.3 billion (as of June 2026, per LinkedIn company page and market data).
- **Key Metric**: Annual revenue of $673 million (most recent fiscal year); total funding of $1.55 billion (including Series A, post-IPO equity, and debt).
- **Notable Investors/Partners**:
  - Investors: Ontario Municipal Employees Retirement System (led $400M post-IPO debt in 2025), multiple venture and institutional investors.
  - Partners: Kyowa Hakko Kirin, Daiichi Sankyo, Mereo BioPharma, Regeneron (non-U.S. commercial rights for evinacumab).
- **Growth Signals**:
  - One of the largest and most diverse pipelines in rare disease.
  - Awarded “Best Place to Work” by BioSpace (2020, 2021) and recognized by Deloitte’s Fast 500.
  - Active job postings: 21 openings as of mid-2026 (LinkedIn), though headcount declined 1.9% YoY to 1,247 employees.
  - Recent news: Ultragenyx Reports Inducement Grant Under Nasdaq Listing Rule 5 (June 2026).

## Competitive Advantages
- **Ultra-rare focus**: Targets diseases with no approved therapies, creating first-ever treatments and building significant regulatory and commercial expertise.
- **Multi-modality platform**: Expertise across biologics, small molecules, gene therapies, ASOs, and mRNA – reducing risk and expanding addressable disease space.
- **Global infrastructure**: Operations in 20 countries (including Brazil, Switzerland, Mexico, Japan) and commercial presence in North America, Europe, Latin America, and Asia.

## Strategic Focus
- **Commercial expansion**: Hiring for Commercial and Medical Affairs teams to support growing product portfolio.
- **Gene therapy manufacturing**: Building a new gene therapy manufacturing facility in the Boston area to scale production for pipeline candidates.
- **Pipeline advancement**: Continued clinical development of gene therapies, ASOs, and mRNA programs for ultra-rare indications.

## Why Work Here
- **Culture**: Described as “inclusive, generous, curious, and humble,” with a strong emphasis on purpose and patient impact. Named a top workplace by BioSpace and Deloitte.
- **Benefits**: Comprehensive coverage starting on day one for all regular full-time employees; includes robust health, retirement, and wellness programs.
- **Work environment**: Hybrid/office model with multiple U.S. hubs (Novato, Brisbane, Boston area) and international offices. Employer rating on LinkedIn: 3.3/5 (324 reviews) with culture rated 3.5, compensation 4.0, and work-life balance 3.2.
- **Career development**: Internships, seasonal co-ops, and postdoctoral programs; strong alumni pipeline to top biopharma companies (Genentech, BioMarin, Vertex, Amgen).

## Sources
1. [ultragenyx.com](https://www.ultragenyx.com/)
2. [ultragenyx.com – Join Our Team](https://www.ultragenyx.com/join-our-team/)
3. [ultragenyx.com – Current Opportunities](https://www.ultragenyx.com/join-our-team/current-opportunities/)
4. [LinkedIn Company Page](https://www.linkedin.com/company/ultragenyx)
5. [talent.ultragenyx.com](https://talent.ultragenyx.com/)
6. [Greenhouse Careers Page](https://job-boards.greenhouse.io/ultragenyxpharmaceutical)

## Other roles at Ultragenyx Pharmaceutical

- [UltraCare Liaison](https://feeny.ai/job/ultracare-liaison-ultragenyx-pharmaceutical-germany-b502ttkt7d2w) — Germany
- [Senior IT Analyst II - IT Research and Development](https://feeny.ai/job/senior-it-analyst-ii-it-research-and-development-ultragenyx-pharmaceutical-v2wsc9qv32cs) — United States
- [Senior Director, US Medical Lead LC-FAOD and MPSs](https://feeny.ai/job/senior-director-us-medical-lead-lc-faod-and-mpss-ultragenyx-pharmaceutical-e9cazv3hfwnx) — United States
- [Medical Director, Japan](https://feeny.ai/job/medical-director-japan-ultragenyx-pharmaceutical-tokyo-gkb6b6jcb7cc) — Tokyo, Japan
- [Facilities Technician II (GMP) – Pitman Schedule (9:00 PM–7:00 AM)](https://feeny.ai/job/facilities-technician-ii-gmp-pitman-schedule-9-00-pm-7-00-am-ultragenyx-q5hahx8cs9n6) — Bedford, MA