---
title: 'Senior Product Manager, AI Platform at Sequencing'
canonical: 'https://feeny.ai/job/senior-product-manager-ai-platform-sequencing-united-states-fraajgrh6tvy'
type: 'job'
last_seen: '2026-09-08'
---

# Senior Product Manager, AI Platform at Sequencing

- **Company:** Sequencing
- **Location:** United States
- **Employment:** full-time
- **Work type:** remote
- **Posted:** 2026-06-08
- **Last confirmed live:** 2026-09-08
- **Apply:** https://jobs.gem.com/sequencing/am9icG9zdDqplHu8DMCLSCgtu56_VOa3

## Job description

The opportunity As Senior Product Manager, AI Platform, you will own the connected intelligence system that allows Sequencing’s current and future AI-powered products to become more contextual, personal, proactive, and valuable over time. Reporting: This role reports to the Senior Director, AI & Emerging Technologies. You will translate customer and business needs into platform capabilities across data, memory, integrations, retrieval, agent orchestration, evaluation, observability, and reliability. You will work closely with Engineering, Bioinformatics, Product, Design, and Customer Success to make the full intelligence pipeline measurable, trustworthy, and ready to support polished product experiences. This is a hands-on, AI-native product role. You should be comfortable prototyping, reading traces, interrogating failure modes, and making informed tradeoffs across deterministic and probabilistic components. You will partner closely with the Senior Product Manager, AI Applications, who owns how these capabilities become a coherent member experience.

## What you’ll own

- The roadmap and PRDs for the intelligence capabilities behind Sequencing’s AI-powered member experiences, including memory, personalization, proactive guidance, integrations, retrieval, agent orchestration, and future platform components.
- Clear system contracts across data inputs, scientific processing, retrieval and tool use, model reasoning, orchestration, and product outputs.
- A rapid prototype-to-decision loop that turns approved product intent into working agentic prototypes with explicit test criteria.
- Evaluation as a release gate, combining deterministic checks, LLM-as-judge methods, human annotation, scientific review, and observable thresholds.
- Platform observability, including trace quality, latency, cost, failure classification, and the evidence needed to make release and investment decisions.
- Cross-functional prioritization that connects Customer Success and product signals to scalable intelligence capabilities.
- The handoff from validated platform capability to polished member and partner experiences, in close partnership with product-surface owners.
- Continuous improvement of reliability, efficiency, and developer usability across the intelligence pipeline.

## Who you are

- You have 7 to 10 years of product management experience, including at least 2 to 3 years shipping production LLM or generative-AI products to real users.
- You have designed or shipped agentic systems involving tool use, orchestration, memory, retrieval, prompts or skills, and evaluation loops.
- You can distinguish using AI from building reliable AI systems, and can explain the architecture, evaluation, failure handling, and operating ownership behind systems you shipped.
- You have used evaluation suites, human annotation, LLM-as-judge methods, or comparable quality gates in production.
- You can prototype, read traces, and reason with engineers about model, data, orchestration, and reliability tradeoffs.
- You turn ambiguous customer and business needs into clear interfaces, measurable requirements, and prioritized delivery plans.
- You are rigorous about health-product trust, uncertainty, privacy, and human scientific review.
- You communicate clearly across Engineering, Bioinformatics, Product, Design, and Customer Success.
- You are based in the United States and comfortable operating autonomously in a fast-moving, fully remote environment. Helpful experience
- Healthcare, genomics, or another regulated and high-consequence domain.
- Consumer conversational products, voice interfaces, or longitudinal personalization.
- Data-platform, developer-platform, or internal-tool product ownership.

## Benefits overview

- Comprehensive medical, dental, and vision insurance coverage
- 401(k) with company matching
- Paid time off (PTO)
- Paid volunteer time off
- Fully remote work with home office stipend
- Parental bonding leave
- Clinical-grade whole genome sequencing for you and your family (private and confidential) Join Sequencing
- Redefine how people understand themselves through their DNA
- Build category-defining products alongside scientists, engineers, and innovators
- Contribute to technology that will improve and extend millions of lives
- Shape one of the most important emerging categories in AI and healthcare Sequencing Inc. is an equal opportunity employer. All aspects of employment, including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. We do not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. Where required by applicable law, candidates may request a reasonable accommodation or an alternative selection process by contacting joinus@sequencing.com.

## About Sequencing

## Company Overview
- **One-liner**: Sequencing is a genomics platform that provides clinical-grade whole genome sequencing, free lifetime DNA data storage, and AI-powered interpretation to deliver personalized health, wellness, and ancestry insights.
- **Entity Type**: Private (seed-stage; $5M total funding)
- **Headquarters**: Pasadena, California, United States
- **Founded**: 2017
- **Founders**: Brandon Colby, MD

## Core Business
- **Primary industry**: Biotechnology Research / Digital Health (genomics, bioinformatics, AI-driven health)
- **Target customers**: B2C (individuals seeking DNA insights), B2B (healthcare professionals, healthtech companies)
- **Mission**: To help everyone outsmart their genes by making genomic data accessible, actionable, and transformative for humanity.

## Products & Services
- **Clinical-Grade Whole Genome Sequencing (WGS)**: 30x coverage WGS service delivered via at-home DNA kit or direct lab partnership.
- **Free Lifetime DNA Data Storage**: Unlimited, secure storage of raw genetic data.
- **App & Report Marketplace**: Ecosystem of third-party and proprietary apps/reports for health, wellness, ancestry, and longevity.
- **AI-Powered Interpretation**: Proprietary algorithms and AI combine bioinformatics with machine learning to generate dynamic, actionable insights.
- **Personalized Health Reports**: Ongoing updates covering disease predisposition, medication response, carrier status, and wellness optimization.

## Market Standing
- **Valuation**: Not publicly disclosed
- **Key Metric**: Annual Revenue ~$8M (LinkedIn estimate); Total Funding $5M (seed rounds)
- **Notable Investors/Partners**: Lerer Hippeau (led $5M seed round in November 2022), plus additional undisclosed investors in subsequent rounds.
- **Growth Signals**: Claims to be the world’s largest provider of clinical-grade WGS by volume; global headcount of ~29 employees distributed across 5 countries; fully remote team; expanding AI and bioinformatics capabilities; hiring for senior roles across engineering, security, marketing, and product.

## Competitive Advantages
- **Scale & Data**: Largest base of clinical-grade whole genomes sequenced, providing a unique foundation for AI training and genomic intelligence.
- **Privacy & Storage**: Free, unlimited DNA data storage with strong emphasis on privacy (HIPAA compliance).
- **Marketplace Model**: Open ecosystem of DNA apps/reports that continuously add value for users.
- **AI-Native Platform**: Combines deterministic bioinformatics with AI reasoning to ensure scientifically accurate, explainable insights.
- **Clinical-Grade Quality**: 30x WGS ensures highest accuracy for actionable health decisions.

## Strategic Focus
- Building the lifelong home for every human genome – a trusted platform for storage, interpretation, and continuous value.
- Expanding the AI-native genomic intelligence layer to support prevention, longevity, and personalized care.
- Growing the developer and partner ecosystem around the Sequencing platform.
- Scaling B2B partnerships with healthcare providers and healthtech companies.
- Preparing for regulatory certifications (SOC 2, ISO 27001) to deepen enterprise trust.

## Why Work Here
- **Culture**: Fully remote, global team of doctors, scientists, engineers, and AI researchers with a mission-driven focus on genomics and health.
- **Work Environment**: Remote-first with offices in Pasadena, Los Angeles, and Sioux Falls; flexible for global time zones.
- **Perks & Engineering Culture**: Opportunity to work at the intersection of genomics, cloud infrastructure (AWS), and AI; emphasis on data privacy, security, and scientific rigor; employee rating 4.0/5.0 on Built In (compensation 4.0, culture 3.1).
- **Growth**: High-impact roles across bioinformatics engineering, AI/ML, security, and product management in a fast-growing startup.

## Sources
1. [sequencing.com](https://sequencing.com/about)
2. [builtin.com](https://builtin.com/company/sequencing-com)
3. [linkedin.com](https://www.linkedin.com/company/sequencing-com)
4. [sequencing.com](https://sequencing.com/knowledge-center/faqs/who-is-sequencing)
5. [builtin.com](https://builtin.com/company/sequencing-com/jobs)

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