---
title: 'Senior Product Manager at Probably Genetic'
canonical: 'https://feeny.ai/job/senior-product-manager-probably-genetic-san-francisco-3dm1840s7tx9'
type: 'job'
last_seen: '2026-09-24'
---

# Senior Product Manager at Probably Genetic

- **Company:** Probably Genetic
- **Location:** San Francisco, CA
- **Compensation:** $155k–$210k
- **Employment:** full-time
- **Posted:** 2026-09-21
- **Last confirmed live:** 2026-09-24
- **Apply:** https://jobs.ashbyhq.com/probablygenetic/e9752d3c-c034-47fd-9740-c81ad2cb4c2b

## Job description

## About Probably Genetic

Probably Genetic is changing the lives of patients living with severe, complex diseases. Our data platform is used by drug developers and patient advocacy groups to develop and launch treatments for these patients. Our technology discovers undiagnosed patients online, analyzes their disease state using machine learning and at-home testing, and enables compliant communication with patients. In doing so, we help patients access diagnoses, clinical trials, and treatments as early as possible. We are a tight-knit group of hard-working, ambitious problem solvers united by a mission greater than ourselves. We do well by doing right by patients. We are developing some of the most cutting-edge solutions in healthcare, and our roadmap is packed with innovations in bioinformatics, AI, and drug development. We have built a lean, all-star team to help us bring our vision to life, and we want you to be a part of it. Probably Genetic has raised multiple rounds of funding from Silicon Valley’s best investors, including Threshold, Khosla, and Y Combinator, and offer competitive salaries, comprehensive benefits, and meaningful early stage equity.

About the role: We are looking for a Senior Product Manager to lead a new product line end to end, owning the vision, strategy, and roadmap that will guide its growth. You will define requirements, run discovery, and partner with engineering to prioritize and ship improvements. You will also own the post-sale relationship for several strategic accounts (biopharma customers, R&D organizations), the primary users of this new product line, serving as an integral link so the voice of the customer stays prevalent across our products, and drives the product development strategy

What you will do:

- Lead a new product line end to end, owning the vision, strategy, and roadmap that will guide its growth
- Define product requirements and write specs, partnering closely with engineering to scope, prioritize, and ship improvements
- Run product discovery, including customer interviews, competitive research, and market analysis, to inform roadmap decisions
- Define success metrics for the product and track performance post launch, iterating based on data
- Ideate, prepare and deliver polished, data-driven insights and presentations that turn raw data into clear, compelling narratives
- Own the full post-sale relationship for key biopharma and R&D accounts, serving as the primary point of contact so the voice of the customer is prevalent across all our products
- Build lightweight AI-assisted tools and automations to streamline workflows and reduce manual effort over time
- Collaborate with leadership on product strategy, account strategy, renewal planning, and expansion opportunities across the biopharma, R&D and insurance portfolio

Who you are: We are looking for a few specific things that will help you succeed in this role:

- 5+ years of experience in product management or data science role combining strategy and execution, ideally in a biopharma or healthtech environment
- Track record of owning a product roadmap end to end, from discovery through shipping and measuring impact
- Strong data fluency, comfortable working in spreadsheets and SQL or Python to pull, clean, and package insights without heavy analytical support. Previous experience as a data scientist or data analyst preferred.
- Excellent written and verbal communication skills, with a track record of producing polished decks, dashboards, and insight summaries
- Excellent organization skills, with an ability to manage complex projects across various cross-functional stakeholders
- AI native, you use AI tools as a core part of your workflow and are comfortable vibe coding lightweight solutions without engineering support
- Experience translating customer or stakeholder feedback into product requirements and working alongside engineering to deliver improvements
- Demonstrated ability to manage senior stakeholder relationships at large organizations, including handling escalations when needed
- A hustler and a self-starter; you don’t just solve problems that others flag to you, you independently identify problems and risks before they happen, and build those solutions proactively into your plan.

Some things that are not required, but you will learn on the job:

- Familiarity with rare disease, genetics, or the biopharma drug development lifecycle
- Experience with patient-facing or healthcare data platforms
- Formal ownership of a customer-facing platform or tool

As with all new hires at Probably Genetic, you will also need to be:

- A good person. We work with some of the most marginalized populations on the planet and empathy is key
- Patient-focused and motivated to have a lasting, positive impact on humanity
- Comfortable in a fast-paced, often ambiguous environment with rapid change
- Action-oriented and excited to build a company from the ground up

The salary range for this role is $155,000-$210,000 annually. Actual compensation offered will depend on several factors including but not limited to: work experience, education, skill level, and/or other business and organizational needs. What we offer at Probably Genetic:

- An engaging and supportive team all on a mission to improve lives
- Fair and equitable compensation with competitive early-stage equity grants
- Generous Flexible Time off policy, that we actually use
- Parental Leave Benefits (12 weeks for both birthing and non-birthing)
- Hybrid, flexible work with high-trust and autonomy
- A bright, inviting, pet-friendly office in Downtown SF near transit
- Company-sponsored team lunch every Thursday
- A “work from anywhere” policy, up to 4 weeks a year
- Regular team retreats in exciting destinations
- Health Benefits including medical, dental, vision, therapy, FSA, and 401k
- And so much more!

Probably Genetic is committed to fostering a welcoming and inclusive work environment for people of all genders, sexuality, ethnicity, socioeconomic background and life experiences. We urge candidates of all backgrounds to apply. If you require specific accommodations as you interview or consider working with us, please let us know.

## About Probably Genetic

## Company Overview
- **One-liner**: Probably Genetic uses AI and at-home genetic testing to help diagnose rare genetic diseases and connect patients to treatments, while powering drug development with real-world data.
- **Entity Type**: Private (Seed-stage; Y Combinator Winter 2019 batch)
- **Headquarters**: San Francisco, California, United States
- **Founded**: 2019 (per Y Combinator; company website states 2018 – conflicting reports)
- **Founders**: Lukas Lange (CEO & Co-Founder)

## Core Business
- **Primary industry**: Healthcare / Genetic Testing / Biotechnology
- **Target customers**: B2B (drug developers, patient advocacy groups, clinical labs) and B2C (patients with undiagnosed rare diseases and their caregivers)
- **Mission**: "We develop AI to diagnose 200+ million patients living with genetic disease to help them access the treatments they need and catalyze drug development."

## Products & Services
- **Probably Genetic Platform (Patient Intelligence Platform)**: End-to-end system that identifies undiagnosed patients via an AI-powered symptom checker, ships at-home saliva or cheek swab kits, provides genetic counseling, and delivers clinical-grade reports. The platform is used by drug developers to discover and engage eligible patients for clinical trials and sponsored testing programs. (SaaS + Services)
- **Free Sponsored Testing Programs**: Offered in partnership with pharmaceutical companies and patient advocacy groups, allowing eligible patients to access genetic testing at no cost.

## Market Standing
- **Valuation**: Not publicly available
- **Key Metric**: Total Funding – USD 11.2 million (as of latest LinkedIn data) across multiple rounds (Pre-Seed led by Y Combinator, Seed, and Angel Round in 2022)
- **Notable Investors/Partners**: Y Combinator, Threshold, Khosla Ventures; partnered with 50+ patient advocacy groups (e.g., NORD, Global Genes)
- **Growth Signals**:
  - 200,000+ patients have used the platform
  - >6x year-over-year revenue growth (self-reported)
  - Profitable (stated on Y Combinator jobs page)
  - Team size: 17 (Y Combinator) vs. 12 (LinkedIn, showing -21.4% YoY headcount decline – conflicting reports)
  - Global reach: services offered internationally

## Competitive Advantages
- Proprietary AI models trained on a large, growing dataset of rare disease phenotypes and genotypes
- Direct-to-consumer at-home testing removes barriers for undiagnosed patients
- CLIA-Certified & CAP-accredited lab; HIPAA-compliant data handling
- Strong integration with drug developer workflows (patient identification, consent, data sharing)

## Strategic Focus
- Expand the dataset and refine AI algorithms to improve diagnostic accuracy for more rare diseases
- Deepen partnerships with pharmaceutical companies to launch new sponsored testing programs
- Scale patient outreach globally, especially in underserved regions
- Advance bioinformatics and machine learning capabilities to accelerate drug development

## Why Work Here
- Mission-driven culture: "We do well by doing right by patients"
- Tight-knit, ambitious team united by a challenging problem
- Remote/hybrid policy: San Francisco headquarters with remote options within the US
- Competitive salaries ($150K–$190K for senior engineering roles) plus meaningful equity
- Notable perks: "Incredible team retreats to places like Barbados, the Alps, Mexico, Costa Rica, and Portugal"
- Y Combinator backing with a profitable, high-growth trajectory

## Sources
1. [probablygenetic.com](https://www.probablygenetic.com/)
2. [probablygenetic.com/about](https://www.probablygenetic.com/about-probably-genetic)
3. [ycombinator.com](https://www.ycombinator.com/companies/probably-genetic)
4. [ycombinator.com/jobs](https://www.ycombinator.com/companies/probably-genetic/jobs)
5. [linkedin.com](https://www.linkedin.com/company/probablygenetic)

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