---
title: 'Senior Quality Bioinformatics Engineer at Sequencing'
canonical: 'https://feeny.ai/job/senior-quality-bioinformatics-engineer-sequencing-united-states-d6xam7mgvqnz'
type: 'job'
last_seen: '2026-09-08'
---

# Senior Quality Bioinformatics Engineer at Sequencing

- **Company:** Sequencing
- **Location:** United States
- **Employment:** full-time
- **Work type:** remote
- **Posted:** 2026-08-18
- **Last confirmed live:** 2026-09-08
- **Apply:** https://jobs.gem.com/sequencing/am9icG9zdDrxK9ALYTpKMPrCT3Tsrvvs

## Job description

The opportunity

We're building AI that can reason over one of the most complex datasets in existence: the human genome. Millions of people trust Sequencing to help them understand their DNA,  which means every variant call, every pipeline output, and every genetic insight we deliver has to be right. As a Senior Quality Bioinformatics Engineer, you'll be the last line of defense between our genomic analysis pipelines and the people who depend on them. You'll combine large-scale data analysis with rigorous test automation to make sure the science stays accurate as our platform scales. This is an opportunity to apply deep bioinformatics expertise to build the quality systems that keep genetic insight trustworthy, for a platform that's reshaping how people understand their own health.

Who you are:

- 5+ years of experience in Bioinformatics, Computational Biology, or a related field.
- Strong programming skills in Python and SQL for genomic data analysis.
- Experience with NGS pipelines, variant classification, and data validation.
- A solid understanding of software testing methodologies and automation tools.
- Experience with bug tracking and Agile tools such as JIRA and Confluence.
- Fluency in English, both written and verbal.

Bonus points for:

- Experience with cloud platforms (AWS, OCI).
- Knowledge of continuous integration (CI/CD) and automated testing frameworks.

## What you'll own

- Develop automated test cases for quality control of new code deployments.
- Write scripts and pipelines to analyze large-scale genomic data and detect errors.
- Work closely with engineers and variant curators to improve workflows and catch issues before they reach production.
- Ensure genetic data accuracy and integrity through quality engineering practices across our analysis pipelines.

Why this role matters For decades, the human genome has been one of the world's richest sources of health information, but only if the insights drawn from it can be trusted. The quality systems you build will make sure that billions of genetic data points, processed through constantly evolving pipelines, translate into genetic insights people can rely on when making decisions about their health. This role sits at the intersection of precision engineering and human genetics. The accuracy you help guarantee is what makes it possible for people to trust their DNA data enough to act on it.

## About Sequencing

## Company Overview
- **One-liner**: Sequencing is a genomics platform that provides clinical-grade whole genome sequencing, free lifetime DNA data storage, and AI-powered interpretation to deliver personalized health, wellness, and ancestry insights.
- **Entity Type**: Private (seed-stage; $5M total funding)
- **Headquarters**: Pasadena, California, United States
- **Founded**: 2017
- **Founders**: Brandon Colby, MD

## Core Business
- **Primary industry**: Biotechnology Research / Digital Health (genomics, bioinformatics, AI-driven health)
- **Target customers**: B2C (individuals seeking DNA insights), B2B (healthcare professionals, healthtech companies)
- **Mission**: To help everyone outsmart their genes by making genomic data accessible, actionable, and transformative for humanity.

## Products & Services
- **Clinical-Grade Whole Genome Sequencing (WGS)**: 30x coverage WGS service delivered via at-home DNA kit or direct lab partnership.
- **Free Lifetime DNA Data Storage**: Unlimited, secure storage of raw genetic data.
- **App & Report Marketplace**: Ecosystem of third-party and proprietary apps/reports for health, wellness, ancestry, and longevity.
- **AI-Powered Interpretation**: Proprietary algorithms and AI combine bioinformatics with machine learning to generate dynamic, actionable insights.
- **Personalized Health Reports**: Ongoing updates covering disease predisposition, medication response, carrier status, and wellness optimization.

## Market Standing
- **Valuation**: Not publicly disclosed
- **Key Metric**: Annual Revenue ~$8M (LinkedIn estimate); Total Funding $5M (seed rounds)
- **Notable Investors/Partners**: Lerer Hippeau (led $5M seed round in November 2022), plus additional undisclosed investors in subsequent rounds.
- **Growth Signals**: Claims to be the world’s largest provider of clinical-grade WGS by volume; global headcount of ~29 employees distributed across 5 countries; fully remote team; expanding AI and bioinformatics capabilities; hiring for senior roles across engineering, security, marketing, and product.

## Competitive Advantages
- **Scale & Data**: Largest base of clinical-grade whole genomes sequenced, providing a unique foundation for AI training and genomic intelligence.
- **Privacy & Storage**: Free, unlimited DNA data storage with strong emphasis on privacy (HIPAA compliance).
- **Marketplace Model**: Open ecosystem of DNA apps/reports that continuously add value for users.
- **AI-Native Platform**: Combines deterministic bioinformatics with AI reasoning to ensure scientifically accurate, explainable insights.
- **Clinical-Grade Quality**: 30x WGS ensures highest accuracy for actionable health decisions.

## Strategic Focus
- Building the lifelong home for every human genome – a trusted platform for storage, interpretation, and continuous value.
- Expanding the AI-native genomic intelligence layer to support prevention, longevity, and personalized care.
- Growing the developer and partner ecosystem around the Sequencing platform.
- Scaling B2B partnerships with healthcare providers and healthtech companies.
- Preparing for regulatory certifications (SOC 2, ISO 27001) to deepen enterprise trust.

## Why Work Here
- **Culture**: Fully remote, global team of doctors, scientists, engineers, and AI researchers with a mission-driven focus on genomics and health.
- **Work Environment**: Remote-first with offices in Pasadena, Los Angeles, and Sioux Falls; flexible for global time zones.
- **Perks & Engineering Culture**: Opportunity to work at the intersection of genomics, cloud infrastructure (AWS), and AI; emphasis on data privacy, security, and scientific rigor; employee rating 4.0/5.0 on Built In (compensation 4.0, culture 3.1).
- **Growth**: High-impact roles across bioinformatics engineering, AI/ML, security, and product management in a fast-growing startup.

## Sources
1. [sequencing.com](https://sequencing.com/about)
2. [builtin.com](https://builtin.com/company/sequencing-com)
3. [linkedin.com](https://www.linkedin.com/company/sequencing-com)
4. [sequencing.com](https://sequencing.com/knowledge-center/faqs/who-is-sequencing)
5. [builtin.com](https://builtin.com/company/sequencing-com/jobs)

## Other roles at Sequencing

- [Senior Applied AI Bioinformatician](https://feeny.ai/job/senior-applied-ai-bioinformatician-sequencing-united-states-m69tcssm87yh) — United States
- [Senior Product Manager, AI Applications](https://feeny.ai/job/senior-product-manager-ai-applications-sequencing-united-states-pedmc3vyd6kp) — United States
- [Director of Growth](https://feeny.ai/job/director-of-growth-sequencing-united-states-bp96dazgk30m) — United States
- [Director of Growth](https://feeny.ai/job/director-of-growth-sequencing-united-states-8ptd5ktnqmqg) — United States
- [Senior Lifecycle Marketing Manager](https://feeny.ai/job/senior-lifecycle-marketing-manager-sequencing-united-states-tcvfm206413c) — United States
- [Senior Bioinformatics Engineer](https://feeny.ai/job/senior-bioinformatics-engineer-sequencing-united-states-y7fmfm7phzkq) — United States
- [Senior Backend Engineer, AI & Bioinformatics (TypeScript)](https://feeny.ai/job/senior-backend-engineer-ai-bioinformatics-typescript-sequencing-united-states-0m8kw9k5103y) — United States
- [Senior AI Bioinformatics Engineer](https://feeny.ai/job/senior-ai-bioinformatics-engineer-sequencing-united-states-n6e6zy6t50na) — United States
- [Senior Backend Engineer (Agentic Data Platform)](https://feeny.ai/job/senior-backend-engineer-agentic-data-platform-sequencing-united-states-ncdhe779q7m5) — United States
- [Customer Success Specialist](https://feeny.ai/job/customer-success-specialist-sequencing-united-states-gcw8hecg3bmm) — United States