--- title: 'Senior Quantitative Scientist at Pedestal Health' canonical: 'https://feeny.ai/job/senior-quantitative-scientist-pedestal-health-research-triangle-park-pw4qvrdcczj1' type: 'job' last_seen: '2026-11-09' --- # Senior Quantitative Scientist at Pedestal Health - **Company:** Pedestal Health - **Location:** Research Triangle Park, NC - **Posted:** 2026-11-04 - **Last confirmed live:** 2026-11-09 - **Apply:** https://job-boards.greenhouse.io/pedestalhealth/jobs/5471947008 ## Job description ## About Pedestal Health Pedestal Health (formerly Target RWE) combines deep health system partnerships, longitudinal data curation at scale, and modern study design to build continuous, high-quality evidence for life sciences organizations. The company partners with pharmaceutical and biotech companies, providers and payers to generate rigorous, multimodal evidence that supports clinical, regulatory and strategic decision-making across the full lifecycle of care. Pedestal Health is committed to advancing medical decision making to improve outcomes for patients. Pedestal Health is a Highlander Health company. Learn more at[pedestalhealth.com](http://pedestalhealth.com/). ## The Role In this role, you will be a foundational member of Pedestal Health’s Quantitative Sciences (QS) organization, helping to establish Pedestal as a leader in rigorous, reproducible, and regulatory-grade evidence generation. You will serve as a scientific owner of Pedestal’s data, developing deep expertise in its structure, quality, and applications while helping to build scalable data validation, curation, and analytic processes that ensure reliability and usability. Working closely with cross-functional partners in Product, Engineering, Clinical Operations, and Medical Science, you will design and execute analyses that demonstrate the value of Pedestal’s data, support customers across life sciences, regulatory, and academic settings, and build scalable, standardized analytic approaches for real-world evidence generation. ## What You'll Do Data Ownership and Quality - You will establish Pedestal Health’s data as a trusted, validated scientific asset. - Ensure Pedestal’s data are accurate, complete, and fit for regulatory and scientific use by building systems and practices that establish trust in data integrity and readiness for analysis. - Develop deep expertise in Pedestal’s data, understanding its structure, provenance, strengths, and limitations. - Design and implement validation frameworks, data quality checks, and “fitness-for-use” assessments. - Create and maintain data dictionaries and documentation that promote transparency and reproducibility. Analytical excellence - You will apply advanced analytic methods and scientific rigor to generate reliable, reproducible, and regulatory-grade real-world evidence from Pedestal’s data assets. - Support the design and execution of retrospective and prospective studies using Pedestal’s data assets. - Develop statistical analysis plans and analytic code for descriptive, comparative, and predictive analyses. - Design and implement scalable, reusable analytic frameworks and modular code structures that support consistent execution across therapeutic areas and data products. - Apply best practices in methodology, version control, code review, and documentation to ensure reproducibility. - Translate complex results into clear visualizations and insights for scientific, regulatory, and client audiences. - Contribute to publications, abstracts, and collaborations that advance Pedestal’s scientific reputation and influence. Cross functional partnership - You will work cross-functionally to connect data, science, and strategy, ensuring Pedestal’s evidence generation aligns with customer needs and business goals. - Partner closely with Commercial, Medical Science, Product, Data Insights, Engineering, and Clinical Operations teams to align on data strategy and analytic priorities. - Serve as the internal “voice of the customer,” anticipating how clients, regulators, and researchers will use Pedestal’s data. - Participate in client and partner meetings to demonstrate the validity and value of Pedestal’s data products. - Leverage your deep knowledge of Pedestal’s data assets to guide internal teams and external partners, anticipating analytical and operational challenges and helping to shape data use strategies. - Translate analytic findings and data characteristics into clear, client-facing materials that demonstrate Pedestal’s data quality, representativeness, and scientific utility. ## What You'll Bring - Advanced degree (MS or PhD) in biostatistics, epidemiology, health economics, bioinformatics, data science, or a related quantitative field. - 5-10+ years of experience working with real-world data (e.g., EMR, claims, registry, or clinical trial data). - Strong programming expertise in R, and experience with reproducible analytic frameworks. - Proven expertise in data quality assessment, validation, and curation workflows. - Demonstrated ability to build and maintain reproducible coding practices and scalable analytic processes that enable efficiency, transparency, and consistency across studies. - Strong communication, presentation and collaboration skills with cross-functional technical and scientific teams. - Demonstrated ability to translate data insights into actionable scientific or business recommendations. ## What We Offer You - Hybrid work — 3 days/week in our new office! - Comprehensive health, dental, and vision coverage for you and your family - 401(k) with company match - Generous PTO and company holidays - Paid parental leave If you are ready to be part of a team where your work truly matters—where your expertise is valued, your growth is supported, and your contributions help shape the future of healthcare—Pedestal Health is the place for you. We’re building something meaningful together, and we’d love for you to be a part of it. Pedestal Health is an equal opportunity employer and seeks candidates from diverse backgrounds and abilities. ## About Pedestal Health ## Company Overview - **One-liner**: Pedestal Health is an integrated evidence generation partner for life sciences organizations, building continuous, longitudinal patient cohorts to support drug development, regulatory decisions, and clinical care. - **Entity Type**: Private (Part of Highlander Health, a venture-backed company co-founded by Amy Abernethy and Brad Hirsch) - **Headquarters**: Durham, North Carolina, USA - **Founded**: The company emerged from the rebranding of Target RWE and NoviSci, announced in May 2026. Target RWE was founded earlier; the current entity is the result of that merger. - **Founders**: Co-CEOs: Amy Abernethy, MD, PhD, and Brad Hirsch, MD ## Core Business - **Primary industry/industries**: Healthcare Technology, Real-World Evidence (RWE), Clinical Research, Life Sciences Data & Analytics - **Target customers**: Pharmaceutical and biotech companies, health systems, payers, and regulatory bodies (FDA/EMA). - **Mission or purpose statement**: To build a modern evidence-generation engine that reduces treatment access time by 50% through continuous evidence and personalized care, moving from episodic, start-from-scratch clinical studies to an infrastructure that compounds over time. ## Products & Services - **Longitudinal Real-World Data Cohorts**: Deeply phenotyped, disease-specific patient datasets (e.g., hepatology, dermatology, gastroenterology) built directly from clinical practice, continuously queried for safety, effectiveness, and regulatory studies. - **Regulatory-Grade Evidence Generation**: Full-service design and execution of externally controlled trials, prospective interventional studies, registries, and traditional real-world evidence studies for submission to FDA/EMA/HTA bodies. - **Headwater Science (Sister Company)**: A methodological and analytical engine offering deep expertise in causal inference, comparative effectiveness, healthcare utilization, and regulatory-grade analytical software. This is a separate but closely integrated entity within Highlander Health. ## Market Standing - **Valuation/Market Cap**: Not publicly disclosed. - **Key Metric**: Formed from the merger of two established companies (Target RWE and NoviSci) with strong existing revenue and partnerships; backed by Highlander Health, which is focused on evidence generation innovation. - **Notable Investors/Partners**: Highlander Health (the lead investor and parent company). Key health system partnerships are highlighted (e.g., University of North Carolina). - **Growth Signals**: Rebranding and strategic merger in May 2026 signals significant capital and strategic ambition. The company is actively hiring across multiple roles (engineering, data science, delivery, finance). Leadership includes former FDA Deputy Commissioner (Amy Abernethy) and founder of a successful clinical trial technology company (Brad Hirsch). ## Competitive Advantages - **Continuous Evidence Infrastructure**: Unlike traditional CROs or data providers, Pedestal builds **continuous** cohorts that compound over time, avoiding the "start from scratch" model for every new study. - **Deep Clinical Domanin Expertise**: Deepest footprint in hepatology, dermatology, and gastroenterology with pre-existing, deeply phenotyped patient populations and long-standing health system relationships. - **Regulatory & C-Suite Credibility**: Leadership team with unparalleled experience (former FDA Principal Deputy Commissioner, founders of successful healthcare tech companies, top clinical researchers). This translates into regulatory-grade outputs trusted by agencies. - **Integrated Methodological Engine (Headwater Science)**: Built-in access to world-class causal inference and data science expertise for complex analytical challenges, a significant moat against generalist competitors. - **Health System Embeddedness**: Data is sourced directly from clinical practice, offering a richer, more longitudinal picture of patient journeys than claims data alone. ## Strategic Focus - **Current priorities**: Expanding into new therapeutic areas beyond their core hepatology, dermatology, and GI strongholds. Scaling the "continuous evidence system" model across more biopharma partners. Integrating more deeply with health system IT for seamless data flow. - **Direction for growth**: Becoming the "evidence infrastructure" for the life sciences industry, moving from project-based work to platform-based, recurring partnerships. Focus on solving the most complex, high-stakes regulatory and access questions. ## Why Work Here - **Culture**: The company emphasizes passion, dedication, and use of patient data to shift the healthcare paradigm. They highlight "diverse and innovative perspectives" as core to their cutting-edge approach. - **Remote/Hybrid Policy**: **Hybrid work** is explicitly offered as a benefit. - **Notable Perks & Benefits**: - Competitive Health Insurance - **Paid Parental Leave** - Professional Development Courses - Employee Recognition Programs - Paid Holidays & Floating Holidays - **401(k) with Company Match & Immediate Vesting** - Paid Time Off - **Engineering/Data Science Culture**: At the intersection of clinical research, data science, and regulatory technology. The work directly impacts drug development timelines and patient access. The team includes world-class biostatisticians, epidemiologists, data engineers, and product managers. For those passionate about data for social impact in health, this is a mission-driven, fast-paced environment backed by deep expertise. ## Sources 1. [Pedestal Health Official Website](https://www.pedestalhealth.com/) 2. [About Us / Leadership](https://www.pedestalhealth.com/about/) 3. [Careers Page (Greenhouse)](https://job-boards.greenhouse.io/pedestalhealth) 4. [Pedestal Health Careers / Benefits](https://www.pedestalhealth.com/careers/) 5. [Yahoo Finance: Target RWE and NoviSci Rebrand as Pedestal Health and Headwater Science](https://finance.yahoo.com/sectors/healthcare/articles/target-rwe-novisci-rebrand-pedestal-110000567.html) ## Other roles at Pedestal Health - [Head of Technology](https://feeny.ai/job/head-of-technology-pedestal-health-research-triangle-park-8bkezczfnq9p) — Research Triangle Park, NC - [People Partner](https://feeny.ai/job/people-partner-pedestal-health-research-triangle-park-c2nk4d7v114c) — Research Triangle Park, NC - [Principal Data Scientist](https://feeny.ai/job/principal-data-scientist-pedestal-health-united-states-zgwh50nmz6gp) — United States - [Director Data Management](https://feeny.ai/job/director-data-management-pedestal-health-united-states-em1ws5k0pbyt) — United States - [Senior AI/ML Engineer](https://feeny.ai/job/senior-ai-ml-engineer-pedestal-health-united-states-4z1bqhq3njgq) — United States