--- title: 'Senior Research Associate/Associate Scientist, Analytical Development (Contractor) at Asimov' canonical: 'https://feeny.ai/job/senior-research-associate-associate-scientist-analytical-development-contractor-33d5zjt4mhr3' type: 'job' last_seen: '2026-11-06' --- # Senior Research Associate/Associate Scientist, Analytical Development (Contractor) at Asimov - **Company:** Asimov - **Location:** Boston, MA - **Compensation:** $40–$55/hr - **Employment:** full-time - **Posted:** 2026-10-16 - **Last confirmed live:** 2026-11-06 - **Apply:** https://jobs.ashbyhq.com/asimov/6b00e0eb-c1d4-470e-a92c-5eb8c9bed414 ## Job description Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We've built a mammalian synthetic biology platform – from cells to software – to enable the design and manufacture of next-generation therapeutics. We are seeking a highly motivated Senior Research Associate or Associate Scientist (Contractor) to join our Analytical Development team for a 6-month contract. In this role, you will run our developability and biophysical screening panel and support routine product-quality (PQ) analytical delivery for our Cell Line Development (CLD) pipeline. You will work hands-on across plate-based and chromatographic assays to characterize antibodies, multispecifics, and other engineered protein formats, generating the data that guides candidate and clone selection. You will be trained and supported by the method owner for each assay, and will grow into independent ownership of routine execution. The ideal candidate is meticulous, enjoys high-throughput laboratory work, and communicates results clearly. About the Role: - Execute the developability and biophysical screening panel at plate scale, including hydrophobic interaction chromatography (HIC), self-association by AC-SINS, thermal stability by differential scanning fluorimetry (DSF), ELISA-based non-specific binding, and size-exclusion chromatography (SEC), delivering ranked, decision-ready data on candidate molecules. - Execute routine PQ analytical delivery for CLD programs, including sample preparation, small-scale Protein A purification, and HPLC/UPLC- and capillary electrophoresis-based assays, meeting delivery timelines and data-quality benchmarks. - Manage high-throughput processing of CLD and screening samples in 96-well format, including system suitability checks, reference standard handling, and use of automated liquid handling where available. - Partner with method owners to complete installation and qualification of new assays, then take ownership of their routine execution, troubleshooting, and performance trending. - Partner with cross-functional teams to communicate analytical results and insights clearly. Manage multiple projects simultaneously, ensuring timely delivery of results and proactive communication with stakeholders. - Drive continuous process and technical improvements, including SOPs and technical reports, while maintaining accurate laboratory notebooks and electronic records, adhering to Good Laboratory Practices (GLP) and safety protocols. - This role is a full-time, 6-month contract with the potential for extension or conversion to a permanent position based on business needs and performance. About You: - You have a B.S. degree in Chemistry, Biochemistry, Biology, or a closely related field with 3+ years of relevant laboratory experience, or an M.S. degree with 1-2 years of relevant experience. Biopharma industry experience is preferred. - You possess hands-on expertise with plate-based assays and microplate readers (e.g., ELISA) and with HPLC/UPLC separations (e.g., SEC, HIC), along with careful small-scale sample preparation for protein analytics. Experience with capillary electrophoresis (CE), UV, and/or MS is a plus. - You are comfortable working in 96-well format at high throughput, with a preference for experience in automated liquid handling (e.g., Hamilton) and high-throughput purification. - You bring exposure to biophysical or developability characterization (thermal stability by DSF, self-association by AC-SINS, hydrophobicity by HIC, non-specific binding) or to label-free binding assays (e.g., Octet BLI). This is a strong plus rather than a requirement; we will train the right candidate. - You have a proven aptitude for troubleshooting analytical instruments and methods with a proactive, solution-oriented approach. - You are proficient in data interpretation and the use of statistical tools for trending, supported by strong communication skills to present complex data clearly to diverse audiences. - You demonstrate the ability to work effectively in a fast-paced, team-oriented environment with meticulous attention to detail and superior organizational skills. We’re fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives. ## About Asimov ## Company Overview - **One-liner**: Asimov builds an integrated platform of cells, genes, and software to program living systems, enabling the design and manufacture of advanced therapies. - **Entity Type**: Private (Series B, raised $175M in January 2023) - **Headquarters**: Boston, Massachusetts, USA (with a second office in Boulder, Colorado) - **Founded**: 2017 - **Founders**: Alec Nielsen (CEO), Chris Voigt, Doug Densmore, Raja Srinivas ## Core Business - **Primary industry/industries**: Synthetic biology, biotechnology, therapeutics manufacturing - **Target customers**: B2B – biotech startups, mid-size biotechs, and large pharmaceutical companies (partnered with over 25 companies) - **Mission or purpose statement**: “To radically advance humanity’s ability to design living systems, enabling biological technologies with outsized societal benefit.” ## Products & Services - **Design Software**: Cloud-based CAD platform to design, simulate, and optimize genetic systems in different cell types. - **Genetic Parts Library**: Over 1,000 experimentally validated genetic parts (transposases, expression vectors, inducible systems, tissue-specific promoters, etc.). - **Host Cell Lines**: Engineered, highly characterized GMP host cells for therapeutic production (CHO, HEK293, etc.) with regulatory documentation. - **LV Edge**: Stable cell lines and software tools for lentiviral titers up to 1E9 TU/mL. - **AAV Edge**: End-to-end payload design and production achieving titers up to 6E15 vg/L. - **RNA Edge**: Sequence design through wet-lab validation in weeks. - **CHO Edge**: Genetic tools and data-driven models delivering titers of 8–12 g/L across modalities. - **Platform Transfer & Full Service**: Two engagement models – customers use the platform in-house, or Asimov performs cell line development and process development at its Boston lab. ## Market Standing - **Valuation/Market Cap**: Not disclosed - **Key Metric**: Total funding of $205M; annual revenue of ~$4.0M (LinkedIn estimate) - **Notable Investors/Partners**: Andreessen Horowitz (seed lead), Horizons Ventures (Series A lead), CPP Investments (Series B lead), DARPA (research support). Partners include 25+ biotechs and pharma companies. - **Growth Signals**: 95 employees (25.8% YoY growth); raised $200M in Series B (Jan 2023); launched AI-driven 4th generation CHO Edge System with increased titer guarantee; expanding into RNA and cell therapy tools. ## Competitive Advantages - Only company offering an end-to-end platform that integrates mammalian synthetic biology, computer-aided design, and machine learning. - Proprietary library of 1,000+ well-characterized genetic parts and GMP-banked host cells. - “We use our own platform every day” – internal R&D teams validate improvements before releasing to customers. - Strong regulatory support (GMP documentation for host cells) that de-risks therapeutic development. ## Strategic Focus - Deepen AI/ML integration into genetic design and cell line development. - Expand platform to cover more therapeutic modalities (cell therapy, RNA therapy, biologics). - Scale partnerships with large pharma while continuing to support early-stage biotechs. - Build out the “first CAD platform for biology” to transition genetic engineering into a fully-fledged engineering discipline. ## Why Work Here - **Culture**: “A culture of recombination” – interdisciplinary team of biologists, engineers, and ML scientists. Values include mission first, urgency, continuous learning, thoughtful communication, and avoiding local optima. - **Work model**: Hybrid – employees engage in a combination of remote and on-site work (Cambridge, MA and Boulder, CO). - **Perks & growth**: Built In profile highlights career growth, compensation & benefits, work-life balance, and stability. The company is actively hiring across roles (Staff Software Engineer, Principal Scientist, Sr. Scientist, Associate Director). - **Impact**: Work at the cutting edge of synthetic biology, directly contributing to the design and manufacture of life-saving therapies. ## Sources 1. [asimov.com](https://www.asimov.com/) 2. [asimov.com/about](https://www.asimov.com/about) 3. [LinkedIn](https://www.linkedin.com/company/asimov) 4. [Built In](https://builtin.com/company/asimov) 5. [Careers Page](https://jobs.ashbyhq.com/asimov) ## Other roles at Asimov - [Principal Scientist, Lentiviral Vector Cell Line Development](https://feeny.ai/job/principal-scientist-lentiviral-vector-cell-line-development-asimov-boston-0p8n91rkhbwh) — Boston, MA - [Senior Associate Scientist, Biologics Downstream Process Development](https://feeny.ai/job/senior-associate-scientist-biologics-downstream-process-development-asimov-nesyzysj6bsz) — Boston, MA - [Scientist, Viral Vector Process Development](https://feeny.ai/job/scientist-viral-vector-process-development-asimov-boston-1qsqy03f8zyb) — Boston, MA - [Scientist, Lentiviral Vector Cell Line Development](https://feeny.ai/job/scientist-lentiviral-vector-cell-line-development-asimov-boston-vhtpf4a8bt9m) — Boston, MA - [Senior Scientist, Analytical Development](https://feeny.ai/job/senior-scientist-analytical-development-asimov-boston-9r1y790704fx) — Boston, MA - [Principal Scientist, Biologics Cell Line Development](https://feeny.ai/job/principal-scientist-biologics-cell-line-development-asimov-boston-zc098zf7xer4) — Boston, MA