---
title: 'Senior Scientist, Analytical Chemistry at Deep Genomics'
canonical: 'https://feeny.ai/job/senior-scientist-analytical-chemistry-deep-genomics-cambridge-wsfp0nvpr58m'
type: 'job'
last_seen: '2026-09-08'
---

# Senior Scientist, Analytical Chemistry at Deep Genomics

- **Company:** Deep Genomics
- **Location:** Cambridge, MA
- **Employment:** full-time
- **Work type:** hybrid
- **Posted:** 2026-05-12
- **Last confirmed live:** 2026-09-08
- **Apply:** https://jobs.lever.co/deepgenomics/ba904bda-e9e1-4cea-a6a4-a10867364aec

## Job description

## About Us

Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of RNA biology to identify novel drug targets, mechanisms, and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team in Toronto and Cambridge, MA is revolutionizing how new medicines are created.

Opportunity This role based in Cambridge, MA is focused on the analytical characterization and formulation of oligonucleotides in support of the research efforts at Deep Genomics.  The individual in this role will assure the identity and purity levels of oligonucleotides as they are obtained from external CROs as well as from pre-clinical in vitro and in vivo metabolism experiments.  The person in this role will also be responsible for the formulation of oligonucleotides for in vitro and in vivo experimentation.  Further, responsibility for the management of research samples falls within the remit of this role.  The person in this role will also lead the strategy formulation and implementation of an internal build of oligonucleotide analytics lab at Deep Genomics.

## Key Responsibilities

- Maintain efficient workflows for analytical characterization of DG oligos  at CROs.
- Working with the leader of Molecular Design Chemistry, develop and implement a potential, future plan for the installation of an LCMS system for analysis of oligonucleotides.
- Act as DG KOL for characterization of oligonucleotides in terms of  identify, purity, and stability.
- Develop analytical methods for the future LCMS system to characterize research oligonucleotide samples including characterization of chemical and metabolic stability.
- Generate Certificate of Analysis reports from such data.
- Perform formulation processes to provide research samples ready for  in vitro and in vivo experimentation including endotoxin analysis.
- Develop and maintain a sample tracking system for the compounds that come into Deep Genomics at Cambridge.
- Future responsibilities may include bioanalysis of PK samples.

## Basic Qualifications

- PhD in analytical, pharmaceutical sciences, or bio-organic chemistry including expertise in HPLC (high pressure liquid chromatography) and mass spectrometry with 2 years experience; MS in similar fields with +5 years experience.
- Excellent communication skills coupled with good collaboration style.
- Experience in the laboratory techniques for oligonucleotides.
- Experience in designing and implementing new processes for oligonucleotide samples.

## Preferred Qualifications

- Experience with oligonucleotide therapeutics, analytics, and formulation.
- Understanding of  in vitro assays and/or in vivo experiment involved in ADAR, siRNA and ASO-modality therapeutics.
- Experience in bioanalysis and GxP methods and laboratory operations would be a benefit.

## What We Offer

- A collaborative and innovative environment at the frontier of computational biology, machine learning, and drug discovery.
- Highly competitive compensation, including meaningful stock ownership.
- Comprehensive benefits - including health, vision, and dental coverage for employees and families, employee and family assistance program.
- Flexible work environment - including flexible hours, extended long weekends, holiday shutdown, unlimited personal days.
- Maternity and parental leave top-up coverage, as well as new parent paid time off.
- Focus on learning and growth for all employees - learning and development budget & lunch and learns.
- Facilities located in the heart of Toronto - the epicenter of machine learning and AI research and development, and in Kendall Square, Cambridge, Mass. - a global center of biotechnology and life sciences.

Deep Genomics encourages applications from all backgrounds who seek the opportunity to build the world's leading AI-driven genetic medicine company.

If you have a disability or special need, accommodation is available on request for candidates taking part in all aspects of the selection process.

*This posting reflects a current vacancy.

We offer competitive compensation aligned with local market benchmarks. The salary range for this role is $150,000 - $180,000, and reflects Cambridge, USA-based roles; compensation may differ for Canada-based candidates.

## About Deep Genomics

## Company Overview
- **One-liner**: Deep Genomics uses an AI‑driven platform built on deep learning and RNA biology to discover and develop genetic medicines.
- **Entity Type**: Private (Series C, $236.7M total funding)
- **Headquarters**: Toronto, Ontario, Canada (with a Boston, MA office)
- **Founded**: 2014
- **Founders**: Brendan Frey, Ph.D.

## Core Business
- **Primary industry**: Biotechnology / AI‑powered drug discovery
- **Target customers**: B2B (pharmaceutical partners) and internal drug development programs; ultimately serves patients with genetic conditions
- **Mission/purpose**: “Building the world’s leading AI‑driven genetic medicine company” – [deepgenomics.com/careers](https://www.deepgenomics.com/careers/)

## Products & Services
- **BioFM (Biological Foundation Model) Platform**: A proprietary AI platform that integrates lab‑in‑the‑loop workflows, model development, fit‑for‑purpose training datasets, and screening technologies to predict pathogenic mutations, identify therapeutic targets, and accelerate drug development. – [linkedin.com](https://linkedin.com/company/deep-genomics)

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed
- **Key Metric**: Total funding of $236.7M (6 rounds); annual revenue estimated at $5M – [linkedin.com](https://linkedin.com/company/deep-genomics)
- **Notable Investors/Partners**: Khosla Ventures (Series A lead), Future Ventures (Series B lead), SoftBank Vision Fund (Series C lead) – [linkedin.com](https://linkedin.com/company/deep-genomics)
- **Growth Signals**: Headcount of 83 (+23.9% YoY); 4 active job postings as of early 2026; offices in Toronto and Boston; strong publication record (over a dozen papers in Nature, Science, Cell) – [linkedin.com](https://linkedin.com/company/deep-genomics), [deepgenomics.com/team](https://www.deepgenomics.com/team)

## Competitive Advantages
- **Proprietary AI platform** that combines deep learning, RNA biology, and automation with an integrated wet‑lab/dry‑lab feedback loop.
- **World‑class scientific team** with expertise spanning AI, genomics, drug development, and clinical research; led by Brendan Frey, a pioneer in deep learning (co‑author of the wake‑sleep algorithm).
- **Strong publication track record** in top‑tier journals, providing a defensible moat in the AI‑biotech space.
- **Lab‑in‑the‑loop approach** that continuously improves model predictions with real experimental data.

## Strategic Focus
- Scaling the BioFM platform to discover and develop a pipeline of genetic medicines.
- Expanding the team across machine learning, computational biology, and in vitro pharmacology (current openings: Senior Research Scientist ML, Senior MLOps Engineer, Senior Research Engineer ML, Associate Director in vitro Pharmacology) – [jobs.lever.co](https://jobs.lever.co/deepgenomics)
- Strengthening clinical development capabilities out of the Boston office.

## Why Work Here
- **Culture**: Collaborative, innovative environment at the intersection of computational biology and drug discovery. Team has published more AI‑meets‑biology papers than any other lab or company.
- **Compensation**: Highly competitive, including meaningful stock ownership; comprehensive health/vision/dental coverage; parental leave top‑up; unlimited personal days.
- **Work environment**: Flexible hours, hybrid/remote options, extended long weekends, holiday shutdown. Offices in Toronto (MaRS Discovery District) and Boston (Kendall Square).
- **Growth**: Strong focus on learning and development (tuition support, lunch‑and‑learns).
- **Employee rating**: 2.8/5.0 on LinkedIn (23 reviews) – mixed feedback on career progression (2.8) but stronger on work‑life balance (3.5) and culture (3.3) – [linkedin.com](https://linkedin.com/company/deep-genomics)

## Sources
1. [deepgenomics.com/careers](https://www.deepgenomics.com/careers/)
2. [linkedin.com/company/deep-genomics](https://linkedin.com/company/deep-genomics)
3. [jobs.lever.co/deepgenomics](https://jobs.lever.co/deepgenomics)
4. [deepgenomics.com/team](https://www.deepgenomics.com/team)
5. [cbinsights.com/company/deep-genomics](https://www.cbinsights.com/company/deep-genomics)

## Other roles at Deep Genomics

- [Senior Research Scientist, Machine Learning (BioFM)](https://feeny.ai/job/senior-research-scientist-machine-learning-biofm-deep-genomics-toronto-00w9gt5xfgam) — Toronto, Canada