---
title: 'Senior Scientist, Operations Investigation Team (OIT) #4936 at GRAIL'
canonical: 'https://feeny.ai/job/senior-scientist-operations-investigation-team-oit-4936-grail-durham-zcz4f510fq9y'
type: 'job'
last_seen: '2026-09-07'
---

# Senior Scientist, Operations Investigation Team (OIT) #4936 at GRAIL

- **Company:** GRAIL
- **Location:** Durham, NC
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-08-18
- **Last confirmed live:** 2026-09-07
- **Apply:** https://jobs.lever.co/grailbio/852cbde3-df09-4c20-8a7c-1b10a6883f1f

## Job description

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

The Senior Scientist is an experienced scientific individual contributor responsible for investigating platform and assay performance issues, identifying root causes, and developing technical solutions to improve platform reliability and operational performance. As a member of the Operations Investigation Team (OIT), this role independently conducts scientific investigations, collaborates across functions, and drives continuous improvement through data-driven problem solving and process optimization. This position works on-site full-time, 5 days/week at our office located in Durham, NC

Responsibilities:

- Independently design, plan, and execute experiments to investigate platform performance issues and support troubleshooting efforts.
- Analyze experimental data, identify root causes, and develop scientifically sound recommendations.
- Develop, optimize, and troubleshoot experimental methods, workflows, and analytical tools to improve platform robustness, reliability, and efficiency.
- Investigate sources of technical variability and recommend corrective and preventive actions.
- Prepare technical reports, presentations, and investigation summaries to communicate findings and recommendations.
- Collaborate with cross-functional teams, including R&D, Operations, Engineering, Quality, Manufacturing, and Data Science, to resolve platform-related issues.
- Provide technical expertise in experimental design, troubleshooting strategies, and data interpretation.
- Contribute to the development of new technologies, analytical tools, and process improvements that enhance platform performance.
- Ensure compliance with laboratory safety, quality, and applicable regulatory standards.
- These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.

Required Qualifications:

- Ph.D. in Molecular Biology, Biochemistry, Biotechnology, or a related scientific discipline with 2+ years of relevant experience; OR Master's degree with 5+ years of relevant experience; OR Bachelor's degree with 8+ years of relevant experience.
- Strong expertise in molecular biology, NGS technologies, assay development, or related experimental disciplines.
- Experience with laboratory or biotech automation platforms (e.g., liquid handlers, robotic workcells, automated sample-processing systems) is highly desirable.
- Proven experience independently designing and executing experiments and solving complex technical problems.
- Demonstrated experience conducting root-cause investigations and developing practical technical solutions.
- Strong scientific communication and technical presentation skills.
- Experience working in regulated laboratory environments is preferred.

Preferred Qualifications:

- Advanced troubleshooting, analytical, and root-cause investigation skills.
- Strong experimental design and data interpretation capabilities.
- Ability to manage multiple investigations and priorities in a fast-paced environment.
- Strong collaboration and communication skills with cross-functional teams.
- Innovative, self-motivated, and results-oriented with a continuous improvement mindset.

Physical Demands and Environment:

- Work may be performed in laboratory and office environments with exposure to biological samples, chemicals, and laboratory equipment.
- Requires appropriate personal protective equipment (PPE).
- May require extended hours to support critical investigations.
- Regular laboratory activities, including pipetting and operation of laboratory instrumentation.

## About GRAIL

## Company Overview
- **One-liner**: GRAIL develops a multi-cancer early detection blood test (Galleri) that screens for many of the deadliest cancer types before symptoms appear.
- **Entity Type**: Public (ticker: GRAL on Nasdaq Global Select Market)
- **Headquarters**: Menlo Park, California, USA
- **Founded**: Not publicly available from provided sources
- **Founders**: Not publicly available from provided sources

## Core Business
- Primary industry: Healthcare diagnostics / biotechnology
- Target customers: B2B (health systems, employers, insurers) and B2C (individuals aged 50+ with elevated cancer risk)
- Mission: "To detect cancer early, when it can be cured."

## Products & Services
- **[Galleri® Test]**: A multi-cancer early detection (MCED) blood test that uses next-generation sequencing, machine learning, and a proprietary methylation platform to identify cancer signals and predict the tissue of origin. Available by prescription in the U.S. as a CLIA-certified, CAP-accredited laboratory-developed test (not yet FDA cleared).

## Market Standing
- **Valuation/Market Cap**: Not publicly available from provided sources (publicly traded; market cap fluctuates)
- **Key Metric**: Over 250,000 Galleri tests commercially delivered as of November 2024; >380,000 participants enrolled across clinical studies; >300 scientific publications and presentations
- **Notable Investors/Partners**: Providence, Quest Diagnostics, athenahealth, Samsung, AstraZeneca, BeniComp, Curative Insurance Company
- **Growth Signals**: Private placement financing of $325 million (October 2025); first healthcare system (Providence) to offer Galleri; collaboration with Samsung for Asia expansion; REACH study enrolling diverse Medicare populations; long-term data from NHS-Galleri trial and PATHFINDER 2 study showing >7-fold increase in cancer detection when added to standard screenings

## Competitive Advantages
- First-of-its-kind multi-cancer early detection test that screens for cancers without recommended screening tests
- Proprietary methylation-based platform combined with machine learning and large-scale clinical data
- Extensive clinical program with >380,000 participants and >300 publications
- CAP-accredited, CLIA-certified lab facilities with >170,000 square feet and capacity for multi-year growth
- Strong IP portfolio and regulatory experience

## Strategic Focus
- Scaling commercial access through health system partnerships, employer/insurer benefits, and digital ordering platforms
- Expanding clinical evidence for diverse populations (REACH study, veterans)
- International expansion (e.g., Asia via Samsung collaboration)
- Building operational foundation as an independent public company post-Illumina spin-off
- Advancing next-generation platform and risk classification tests (e.g., lung cancer study with AstraZeneca)

## Why Work Here
- Mission-driven culture focused on solving a high-impact problem (early cancer detection)
- Recognized as a 2025 Best Place to Work by Built In and BioSpace; Fortune Change the World list (2023)
- Multidisciplinary team spanning biotech, genomics, data science, clinical development, and commercial operations
- Benefits include competitive salaries, comprehensive health coverage (medical, dental, vision), and flexible time off
- Emphasis on collaboration, agility, courage, and data-driven decision-making
- Remote/hybrid policy not specified in provided sources; office locations include Menlo Park, CA

## Sources
1. [grail.com/careers](https://grail.com/careers/)
2. [grail.com](https://grail.com/)
3. [grail.com/about-us](https://grail.com/about-us/)
4. [jobs.lever.co/grailbio](https://jobs.lever.co/grailbio)
5. [investors.grail.com (SEC Filing)](https://investors.grail.com/static-files/6f7d7c6d-1d22-4045-a6b3-bf4893548649)

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