--- title: 'Senior Software Engineer - Commercial - #4978 at GRAIL' canonical: 'https://feeny.ai/job/senior-software-engineer-commercial-4978-grail-sunnyvale-4993tw69v3h7' type: 'job' last_seen: '2026-10-19' --- # Senior Software Engineer - Commercial - #4978 at GRAIL - **Company:** GRAIL - **Location:** Sunnyvale, CA - **Employment:** full-time - **Work type:** hybrid - **Posted:** 2026-10-13 - **Last confirmed live:** 2026-10-19 - **Apply:** https://jobs.lever.co/grailbio/1676c228-f54e-4d3f-a852-05a64ffec497 ## Job description Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care. We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges. GRAIL is headquartered in the Bay Area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit grail.com GRAIL is seeking a Senior Software Engineer for the Commercial engineering team within our Technology organization. Our team builds and operates the patient- and provider-facing software behind the Galleri® test, including my.grail.com and provider.grail.com, along with the systems that collect and deliver the clinical data the test depends on. The software we write sits directly in the path between a patient ordering a test and a physician acting on the result, so correctness, reliability, and clarity matter as much as velocity. This is a backend-leaning full-stack role for an engineer who wants meaningful ownership. You will design and build cloud-native services in Go on AWS and Kubernetes, and you will follow your work through to the React interfaces that patients and clinicians actually use. You will own systems end to end — design, implementation, testing, rollout, and production operation — and you will help raise the bar for the engineers around you. If you want your work to have a direct line to earlier cancer detection, this is a rare place to do it. This role is based in Sunnyvale, California. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site. At our Sunnyvale campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities. ## Responsibilities - Design, build, and operate backend services and distributed systems that power GRAIL's commercial offerings for the Galleri® test, including my.grail.com and provider.grail.com. - Own features and services end to end, from technical design through implementation, testing, deployment, and production support. - Contribute across the stack, building and maintaining React interfaces used by patients, clinicians, and internal clinical operations teams. - Lead the technical design of projects of diverse scope, working independently and bringing designs forward for review at critical decision points. - Devise solutions where precedent is limited, adapting existing approaches and exercising judgment to select the right course of action. - Partner with product managers, clinical operations, and other engineering teams to turn ambiguous requirements into clear technical plans, advising senior stakeholders who may not share your technical background and adapting how you communicate to the audience. - Write and maintain automated tests and test protocols appropriate for software operating in a regulated healthcare environment. - Improve the reliability and observability of the systems you own, participating in on-call rotation, incident response, and follow-up remediation. - Raise engineering quality on the team through code review, pairing, and mentorship of less experienced engineers. - Identify and drive improvements to our tooling, CI/CD pipelines, and development practices. These responsibilities summarize the role's primary responsibilities and are not an exhaustive list. They may change at the company's discretion. Required Qualifications - Bachelor's degree in Computer Science, Electrical Engineering, Bioinformatics, or a similar technical field with 5+ years of related experience, or a Master's degree with 2+ years of related experience, or a PhD, or equivalent experience. - Professional experience designing, developing, testing, and maintaining production backend or full-stack applications. - Professional experience building and operating services on a major cloud platform such as AWS, GCP, or Azure. - Proficiency in at least one backend programming language such as Go, Java, Python, or C++. - Strong professional written and verbal communication skills. ## Preferred Qualifications - Experience writing production Go, and experience with gRPC-based service communication. - Experience building and maintaining production React applications. - Hands-on experience with AWS specifically, including infrastructure as code using Terraform. - Experience operating containerized workloads with Kubernetes and Docker in production. - Experience designing and scaling microservice architectures, including service boundaries, versioning, and backward compatibility. - Strong working knowledge of relational databases such as PostgreSQL or MySQL, including schema design and query performance, and of caching layers such as Redis. - Experience with CI/CD pipelines, automated testing strategies, and agile development practices. - Experience building software in healthcare or another regulated domain, including familiarity with HIPAA, PHI handling, or software quality and validation requirements. - Experience with observability and reliability tooling, and a track record of improving system uptime. - Experience mentoring engineers or leading small project teams. - A demonstrated passion for designing and building practical, high-quality software, and a desire to add value to the team. The expected, full-time, annual base pay scale for this position is $169K- $180K. At GRAIL, we believe in recognizing and rewarding the contributions our employees make to our mission and success. In addition to base pay, this role may be eligible for additional compensation, including an annual bonus and/or other incentives, in accordance with applicable plans and the company's discretion. The posted range reflects our good-faith estimate of the base pay we expect to offer for this position at the time of hire. Actual compensation will be determined based on factors such as the candidate’s experience, skills, qualifications, and other relevant considerations. At GRAIL, we invest in the health, well-being, and future of our employees and their families. Employees in this role are eligible for a comprehensive and competitive benefits package designed to support what matters most, including flexible time off or vacation, a 401(k) retirement plan with employer match, medical, dental, and vision coverage, and thoughtfully selected well-being programs. Benefits are offered in accordance with applicable plans and policies. GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position. GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us! Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. ## About GRAIL ## Company Overview - **One-liner**: GRAIL develops a multi-cancer early detection blood test (Galleri) that screens for many of the deadliest cancer types before symptoms appear. - **Entity Type**: Public (ticker: GRAL on Nasdaq Global Select Market) - **Headquarters**: Menlo Park, California, USA - **Founded**: Not publicly available from provided sources - **Founders**: Not publicly available from provided sources ## Core Business - Primary industry: Healthcare diagnostics / biotechnology - Target customers: B2B (health systems, employers, insurers) and B2C (individuals aged 50+ with elevated cancer risk) - Mission: "To detect cancer early, when it can be cured." ## Products & Services - **[Galleri® Test]**: A multi-cancer early detection (MCED) blood test that uses next-generation sequencing, machine learning, and a proprietary methylation platform to identify cancer signals and predict the tissue of origin. Available by prescription in the U.S. as a CLIA-certified, CAP-accredited laboratory-developed test (not yet FDA cleared). ## Market Standing - **Valuation/Market Cap**: Not publicly available from provided sources (publicly traded; market cap fluctuates) - **Key Metric**: Over 250,000 Galleri tests commercially delivered as of November 2024; >380,000 participants enrolled across clinical studies; >300 scientific publications and presentations - **Notable Investors/Partners**: Providence, Quest Diagnostics, athenahealth, Samsung, AstraZeneca, BeniComp, Curative Insurance Company - **Growth Signals**: Private placement financing of $325 million (October 2025); first healthcare system (Providence) to offer Galleri; collaboration with Samsung for Asia expansion; REACH study enrolling diverse Medicare populations; long-term data from NHS-Galleri trial and PATHFINDER 2 study showing >7-fold increase in cancer detection when added to standard screenings ## Competitive Advantages - First-of-its-kind multi-cancer early detection test that screens for cancers without recommended screening tests - Proprietary methylation-based platform combined with machine learning and large-scale clinical data - Extensive clinical program with >380,000 participants and >300 publications - CAP-accredited, CLIA-certified lab facilities with >170,000 square feet and capacity for multi-year growth - Strong IP portfolio and regulatory experience ## Strategic Focus - Scaling commercial access through health system partnerships, employer/insurer benefits, and digital ordering platforms - Expanding clinical evidence for diverse populations (REACH study, veterans) - International expansion (e.g., Asia via Samsung collaboration) - Building operational foundation as an independent public company post-Illumina spin-off - Advancing next-generation platform and risk classification tests (e.g., lung cancer study with AstraZeneca) ## Why Work Here - Mission-driven culture focused on solving a high-impact problem (early cancer detection) - Recognized as a 2025 Best Place to Work by Built In and BioSpace; Fortune Change the World list (2023) - Multidisciplinary team spanning biotech, genomics, data science, clinical development, and commercial operations - Benefits include competitive salaries, comprehensive health coverage (medical, dental, vision), and flexible time off - Emphasis on collaboration, agility, courage, and data-driven decision-making - Remote/hybrid policy not specified in provided sources; office locations include Menlo Park, CA ## Sources 1. [grail.com/careers](https://grail.com/careers/) 2. [grail.com](https://grail.com/) 3. [grail.com/about-us](https://grail.com/about-us/) 4. [jobs.lever.co/grailbio](https://jobs.lever.co/grailbio) 5. 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