---
title: 'Senior Software Engineer at Heartflow'
canonical: 'https://feeny.ai/job/senior-software-engineer-heartflow-san-francisco-pztayfdt8kmg'
type: 'job'
last_seen: '2026-10-12'
---

# Senior Software Engineer at Heartflow

- **Company:** Heartflow
- **Location:** San Francisco, CA
- **Posted:** 2026-10-07
- **Last confirmed live:** 2026-10-12
- **Apply:** https://job-boards.greenhouse.io/heartflowinc/jobs/6218992004

## Job description

Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis—provides a color-coded, 3D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFRCT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare.

Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 750,000 patients worldwide.

We are seeking a collaboratively-minded Senior Software Engineer with a foundation in statistical data analysis and algorithm development. In this role, you will lead high-impact projects in a regulated medical environment to deepen our understanding of how real-world imaging conditions impact algorithm accuracy and reproducibility. If you are passionate about directly contributing to patient outcomes and have a track record of driving new data-centric product initiatives, we look forward to reading your application.

What You'll Do:

- Build robust analytical pipelines and visualizations over population-scale data to characterize dataset distributions and algorithm performance across diverse patient populations.
- Translate findings about data variance and algorithm behavior into actionable requirements and algorithmic design recommendations.
- Formulate data annotation protocols for internal product development and FDA submissions.
- Collaborate cross-functionally with Research, Product, Clinical, and Engineering to transform clinical needs into cloud-based software solutions.
- Lead regulatory submission efforts, ensuring that software components comply with relevant regulations by working closely with quality and regulatory teams.
- Lead technical projects from conception to deployment.
- Foster team growth through technical leadership and knowledge sharing.
- Diagnose and resolve complex technical issues across distributed systems, often under time constraints.

Knowledge, Skills, and Abilities:

- Master's or Ph.D. degree in Data Science, Computer Science, Statistics, Biomedical Engineering, or a related quantitative field.
- 5+ years (or 3+ with a PhD) of industry experience in Data Science, Biomedical Signal Analysis, or Biomedical Image Analysis.
- Expert proficiency in Python and statistical data analysis ecosystems (e.g., pandas, bokeh, statsmodels, or other similar libraries).
- Proven experience working with large, complex, and messy datasets.
- Strong interpersonal communicator comfortable with presenting results and recommendations to stakeholders.
- Team-oriented mindset that finds satisfaction in collaborating on difficult problems and providing mentorship.
- Proven experience with regulatory submissions, developing medical software in FDA, MDR, or similarly regulated environments.
- Experience in image processing, computer vision, or 3D computational geometry.
- Demonstrated experience with software development best practices: testing, CI/CD, and agile methodologies.
- Proficiency with orchestration tools, like GitHub Actions, and navigation of Linux systems using the CLI.
- Excellent troubleshooting and diagnostic skills across applications, networks, and cloud environments.

How To Stand Out:

- Experience collaborating directly with Product and Research teams to develop software solutions addressing real-world medical challenges.
- Deep knowledge of statistical methods, image optimization techniques, and advanced visualization tools.
- Familiarity with HIPAA compliance and data security best practices in healthcare.
- Contributions to open-source projects or publications in relevant technical or clinical fields.

If you don't tick every box, don't count yourself out! Our team cares more about finding enthusiastic people than it does ticking boxes, so if this post speaks to you, please apply.

Why Join Us:

You will work on products that directly improve patient care and clinical outcomes, tackling complex challenges with a team of fellow healthcare technology enthusiasts. Join our team to advance healthcare technology, lead innovative projects, and grow professionally in a collaborative and dynamic setting.

A reasonable estimate of the base salary compensation range is $180,000 to $215,000, bonus, and equity. #LI-IB1 Heartflow is an Equal Opportunity Employer. We are committed to a work environment that supports, inspires, and respects all individuals and do not discriminate against any employee or applicant because of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. This policy applies to every aspect of employment at Heartflow, including recruitment, hiring, training, relocation, promotion, and termination.

Positions posted for Heartflow are not intended for or open to third party recruiters / agencies. Submission of any unsolicited resumes for these positions will be considered to be free referrals.

Heartflow has become aware of a fraud where unknown entities are posing as Heartflow recruiters in an attempt to obtain personal information from individuals as part of our application or job offer process. Before providing any personal information to outside parties, please verify the following: A) all legitimate Heartflow recruiter email addresses end with “@heartflow.com” and B) the position described is found on our careers site at [www.heartflow.com/about/careers/](https://www.heartflow.com/about/careers/).

## About Heartflow

## Company Overview
- **One-liner**: Heartflow is a medical technology company that leverages AI to create personalized 3D models of the heart from a single CT scan, enabling clinicians to diagnose, treat, and manage coronary artery disease (CAD) non-invasively.
- **Entity Type**: Public (NASDAQ: HTFL) – IPO in 2025
- **Headquarters**: San Francisco, California, USA
- **Founded**: 2007
- **Founders**: Not publicly listed on primary company pages; the company was founded by a team including Dr. Charles Taylor (inventor of the core technology). *Note: Founders not explicitly named on the main website.*

## Core Business
- **Primary Industry**: Medical Technology / HealthTech / AI-Driven Diagnostics (Cardiology)
- **Target Customers**: B2B – Hospitals, health systems, and cardiology clinics; the end-users are clinicians (cardiologists, radiologists) and the ultimate beneficiaries are patients with suspected or known CAD.
- **Mission/Purpose**: To transform coronary artery disease (CAD) from the leading cause of death into a disease that can be managed for life.

## Products & Services
- **Heartflow One Platform**: The company’s core AI-driven, non-invasive precision coronary care platform. It provides a suite of analyses from a single Coronary CTA (CCTA) scan:
    - **Roadmap™ Analysis**: Visualizes the coronary anatomy and assesses blood flow anywhere in the coronary tree.
    - **FFRct Analysis**: Computes Fractional Flow Reserve from CT, determining the functional significance of a blockage (the original, most established product).
    - **Plaque Analysis**: Quantifies and characterizes plaque to inform risk stratification and disease management.
    - **Type**: SaaS/Software-as-a-Medical-Device (SaMD) integrated into clinical workflow.

## Market Standing
- **Valuation/Market Cap**: Not publicly available from the provided sources. As a recently public company (2025), market cap fluctuates. *Source: LinkedIn indicates a 2025 IPO.*
- **Key Metric**: Over **650,000 patients treated**; over **1,800 institutions** using the platform; **99.5% of U.S. lives covered** for FFRct Analysis.
- **Notable Investors/Partners**: Not listed in the provided search results. The company is now public.
- **Growth Signals**:
    - Supported by scientific statements from the American College of Cardiology (ACC) and American Heart Association (AHA) for personalized CAD management.
    - Late-breaking data at AHA 2025 reinforced the prognostic power of its Plaque Analysis.
    - Growing evidence base across the CAD care continuum, from risk stratification to CT-guided intervention planning.
    - Backed by **>625 peer-reviewed publications**.
    - LinkedIn follower growth: +32% year-over-year, indicating strong brand and market interest.

## Competitive Advantages
- **First-Mover & Gold Standard in FFRct**: Heartflow created the FFRct technology category and has the most robust clinical evidence base (over 625 peer-reviewed publications) and guideline support (ACC/AHA).
- **Integrated Platform (Heartflow One)**: It is the only complete, non-invasive, precision coronary care platform that covers the entire guideline-directed CCTA pathway (anatomy, physiology, and plaque).
- **Massive Clinical & Reimbursement Moat**: Achieving 99.5% U.S. lives covered creates an enormous barrier to entry for competitors, as reimbursement and clinical adoption are already deeply established.
- **AI-First, Non-Invasive Solution**: Replaces invasive diagnostic procedures (cardiac catheterization) with a safer, cheaper, and more comfortable CT scan, aligning with the industry shift toward value-based care.

## Strategic Focus
- **Deepening the Evidence Base**: Continuing to publish clinical data to expand the use cases for its platform (e.g., from diagnosis to guiding interventions).
- **Global Expansion**: Operating in the US, Europe, and Japan, with a focus on expanding access and adoption in these key markets.
- **Platformization**: Moving from a single product (FFRct) to a comprehensive CAD management platform (Heartflow One) that manages patients from screening through treatment.
- **Lifecycle Management**: Shifting the narrative from a one-time diagnostic test to a tool for managing CAD for the patient's entire life.

## Why Work Here
- **Mission-Driven**: The work directly impacts the world's leading cause of death. The company culture emphasizes a "patient-first" mentality.
- **Remote-First Culture**: The company is remote-first with employees across the US, Europe, and Japan. Hubs include San Francisco (HQ), Austin, London, and Tokyo.
- **Strong Benefits**: Medical/Dental/Vision (90% of premium paid by company), 401k match, parental leave, flexible PTO, and an Employee Assistance Program (EAP).
- **Engineering & Clinical Excellence**: A high-caliber team of engineers, data scientists, and clinicians working on cutting-edge AI in a regulated medical environment. The tech stack involves complex 3D modeling, AI/ML, and cloud infrastructure.
- **Growth Stage**: As a recently public company with strong adoption, it offers a balance of startup energy and established market stability. High growth potential in a mission-critical field.

## Sources
1. [heartflow.com (Company Overview)](https://www.heartflow.com/)
2. [heartflow.com (About Us)](https://www.heartflow.com/about/)
3. [heartflow.com (Careers Page)](https://www.heartflow.com/about/careers/)
4. [Greenhouse (Job Board)](http://job-boards.greenhouse.io/heartflowinc)
5. [LinkedIn (Company Profile)](https://www.linkedin.com/company/heartflow-inc)

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