---
title: 'Senior Software Engineer at Mithrl'
canonical: 'https://feeny.ai/job/senior-software-engineer-mithrl-san-francisco-2apn6aq88c90'
type: 'job'
last_seen: '2026-09-06'
---

# Senior Software Engineer at Mithrl

- **Company:** Mithrl
- **Location:** San Francisco, CA
- **Compensation:** $175k–$220k
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-01-08
- **Last confirmed live:** 2026-09-06
- **Apply:** https://jobs.ashbyhq.com/mithrl/c8cff948-a000-4d8b-93d4-f33f66c09ee9

## Job description

## ABOUT MITHRL

We imagine a world where new medicines reach patients in months, not years, and where scientific breakthroughs happen at the speed of thought.

Mithrl is building the world’s first commercially available AI Co-Scientist. It is a discovery engine that transforms messy biological data into insights in minutes. Scientists ask questions in natural language, and Mithrl responds with real analysis, novel targets, hypotheses, and patent-ready reports.

Our traction speaks for itself:

- 12X year-over-year revenue growth
- Trusted by leading biotechs and big pharma across three continents
- Driving real breakthroughs from target discovery to patient outcomes.

## ABOUT THE ROLE

We are hiring a Senior Full Stack Engineer to help build, scale, and evolve the core Mithrl product. This is a highly product-oriented engineering role with deep ownership across frontend, backend, and system design. You will work closely with product, design, ML, and scientific teams to turn complex scientific workflows into intuitive, high-performance software used daily by world-class researchers.

As a senior engineer, you will be responsible not just for execution, but for technical direction, architectural decisions, and setting engineering standards. You will own features end-to-end, from initial concept through production, iteration, and scale. This role requires strong full-stack engineering fundamentals, a bias toward shipping, and the ability to operate comfortably in ambiguous, fast-moving environments.

If you enjoy building real products used by sophisticated users, thinking deeply about system design and user experience, and taking ownership of critical parts of a fast-growing platform, this role is an ideal match.

## WHAT YOU WILL DO

- Design, build, and maintain core Mithrl product features across frontend and backend
- Own end-to-end feature development, from product requirements to production deployment and iteration
- Build intuitive user interfaces that abstract complex scientific and data workflows
- Develop scalable backend services, APIs, and data pipelines that power the Mithrl platform
- Collaborate closely with product, design, ML, and scientific teams to translate user needs into technical solutions
- Make architectural decisions that balance speed, scalability, reliability, and developer velocity
- Improve system performance, reliability, and observability as usage and data volumes grow
- Write clean, maintainable, and well-tested code that sets a high bar for quality
- Mentor junior engineers and contribute to raising the overall engineering bar
- Participate in technical planning, code reviews, and ongoing platform evolution

## WHAT YOU BRING

Required Qualifications

- 7+ years of professional software engineering experience
- Strong full-stack engineering experience with Python and React in production environments
- Proficiency in Django for building backend APIs, services, and data-intensive systems
- Strong experience building modern frontend applications using React
- Experience designing and working with GraphQL APIs, including schema design, performance considerations, and client-server data modeling
- Experience designing and working with scalable systems, databases, and data-intensive applications
- Strong understanding of system design, software architecture, and engineering best practices
- Experience shipping and owning production systems used by real customers
- Ability to work effectively in fast-paced, ambiguous environments
- Strong problem solving skills and a product-oriented mindset
- Excellent communication skills and ability to collaborate cross-functionally

## Nice to Have

- Experience building products for technical or scientific users
- Familiarity with data-heavy, analytics, or ML-enabled platforms
- Experience with cloud infrastructure such as AWS, GCP, or Azure
- Experience mentoring or leading other engineers
- Exposure to biotech, life sciences, or R&D workflows

## WHAT YOU WILL LOVE AT MITHRL

- High ownership and impact: You will own meaningful parts of a category-defining product used by leading pharma and biotech organizations. Your work will directly shape how scientists interact with AI and data on a daily basis
- Team: Join a tight-knit, talent-dense team of engineers, scientists, and builders
- Culture: We value consistency, clarity, and hard work. We solve hard problems through focused daily execution
- Speed: We ship fast (2x/week) and improve continuously based on real user feedback
- Location: Beautiful SF office with a high-energy, in-person culture
- Benefits: Comprehensive PPO health coverage through Anthem (medical, dental, and vision) + 401(k) with top-tier plans

We encourage you to apply even if you do not believe you meet every single qualification. Not all strong candidates will meet every single qualification as listed. Research shows that people who identify as being from underrepresented groups are more prone to experiencing imposter syndrome and doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely and to submit an application if you’re interested in this work. We think AI systems like the ones we’re building have enormous social and ethical implications. We think this makes representation even more important, and we strive to include a range of diverse perspectives on our team.

## About Mithrl

## Company Overview
- **One-liner**: Mithrl builds a scientific decision engine that uses natural language to generate transparent, auditable analysis pipelines for biomedical R&D, accelerating discovery from raw data to actionable insights in minutes instead of weeks.
- **Entity Type**: Private (Seed stage)
- **Headquarters**: San Francisco, California, United States
- **Founded**: 2023
- **Founders**: Vivek Adarsh (Co-Founder & CEO), Shara Balakrishnan (Co-Founder & CTO)

## Core Business
- **Primary industry/industries**: Biomedical research software; AI-driven drug discovery and biomarker analysis
- **Target customers**: B2B; pharma and biotech R&D teams (enterprise), discovery researchers across therapeutic areas
- **Mission or purpose statement**: “Help R&D teams go from idea to IND, 50% faster” [mithrl.com/company](https://www.mithrl.com/company)

## Products & Services
- **Mithrl Platform (Scientific Decision Engine)**: An enterprise SaaS platform that takes raw omics and other discovery data, processes it through AI-built custom workflows, and produces defensible, reproducible insights. Users interact via natural language, eliminating manual coding and pipeline setup. [mithrl.com](https://www.mithrl.com/)
- **Eos (mentioned on website)**: Likely a component or interface of the platform (details not fully available).

## Market Standing
- **Valuation/Market Cap**: Not disclosed (private company)
- **Key Metric**: Total Funding of USD $4.0M (Seed round, led by Bonfire Ventures, November 2024) [LinkedIn](https://www.linkedin.com/company/mithrl-ai)
- **Notable Investors/Partners**: Bonfire Ventures (lead investor); Board member Brett Queener
- **Growth Signals**: 100% headcount growth year-over-year (from 11 to 20 employees); 15 active job postings; website traffic up 199% yearly; LinkedIn followers up 145.7% year-over-year to ~6,400; recently published a paper on “the Era of the AI Co-Scientist” [LinkedIn](https://www.linkedin.com/company/mithrl-ai)

## Competitive Advantages
- **Speed & Automation**: Reduces typical analysis cycles from weeks to minutes (32x acceleration claimed) using natural language input, without requiring coding skills.
- **Transparency & Reproducibility**: Every step of the pipeline is auditable; results can be mapped to known biology, pathways, and literature, meeting regulatory-quality standards for IND filings.
- **Domain Expertise**: Built by scientists for scientists — founders and team have deep experience in biology, engineering, and AI, targeting the gap between biological intuition and computational insight. [mithrl.com/company](https://www.mithrl.com/company)

## Strategic Focus
- **Current priorities**: Continue scaling the platform to serve more enterprise pharma/biotech clients; accelerate the path from hypothesis to IND decision; expand capabilities across multiple therapeutic areas and data types (omics and beyond).
- **Direction for growth**: Growing the engineering and scientific AI team (multiple open roles), increasing market presence in drug discovery and biomarker identification.

## Why Work Here
- **Culture**: The company was built “by scientists, for scientists” — a team of biologists, engineers, and AI researchers who understand the pain of analysis backlogs. Emphasis on moving fast, using the latest AI tools, and directly impacting real drug discovery timelines. [builtinsf.com](https://www.builtinsf.com/company/mithrl)
- **Work Policy**: In-office (HQ in San Francisco’s 44 Montgomery St); all employees work from physical office. [builtinsf.com](https://www.builtinsf.com/company/mithrl)
- **Notable Perks & Engineering Culture**: Roles span Forward Deployed Engineer, ML Engineer, Bioinformatics Engineer, Data Engineer — indicating a tight connection between product engineering and scientific end-users. Rapid growth (100% headcount increase) suggests a high-energy, scaling startup environment. 15 open positions (as of mid-2025) offer significant ownership opportunities.

## Sources
1. [mithrl.com](https://www.mithrl.com/)
2. [mithrl.com/company](https://www.mithrl.com/company)
3. [LinkedIn](https://www.linkedin.com/company/mithrl-ai)
4. [builtinsf.com](https://www.builtinsf.com/company/mithrl)

## Other roles at Mithrl

- [Enterprise Account Executive](https://feeny.ai/job/enterprise-account-executive-mithrl-san-francisco-7c521br0pfxk) — San Francisco, CA
- [Application Scientist](https://feeny.ai/job/application-scientist-mithrl-san-francisco-chw2jnarq189) — San Francisco, CA
- [Design Technologist](https://feeny.ai/job/design-technologist-mithrl-san-francisco-4vdb5dv9k4k4) — San Francisco, CA
- [Data Engineer, Scientific Data Ingestion](https://feeny.ai/job/data-engineer-scientific-data-ingestion-mithrl-san-francisco-nf23typhzby9) — San Francisco, CA
- [ML Engineer, Discovery Applications](https://feeny.ai/job/ml-engineer-discovery-applications-mithrl-san-francisco-g36gc1p4xbra) — San Francisco, CA
- [ML Engineer, Biological Analysis & Simulation](https://feeny.ai/job/ml-engineer-biological-analysis-simulation-mithrl-san-francisco-dhbn7wj0zte5) — San Francisco, CA
- [Bioinformatics Engineer, Pipelines](https://feeny.ai/job/bioinformatics-engineer-pipelines-mithrl-san-francisco-spne2m87s85g) — San Francisco, CA
- [Data Scientist, Knowledge Graphs](https://feeny.ai/job/data-scientist-knowledge-graphs-mithrl-san-francisco-zmyfmxnqk200) — San Francisco, CA
- [Data Engineer, Knowledge Graphs](https://feeny.ai/job/data-engineer-knowledge-graphs-mithrl-san-francisco-b38gr7055zhy) — San Francisco, CA
- [QA Engineer, Scientific Workflows](https://feeny.ai/job/qa-engineer-scientific-workflows-mithrl-san-francisco-nw7h6bfj466w) — San Francisco, CA