---
title: 'Senior Statistician, Research & Development at Loyal'
canonical: 'https://feeny.ai/job/senior-statistician-research-development-loyal-united-states-0r3knng5j7zr'
type: 'job'
last_seen: '2026-09-10'
---

# Senior Statistician, Research & Development at Loyal

- **Company:** Loyal
- **Location:** United States
- **Work type:** remote
- **Posted:** 2026-09-08
- **Last confirmed live:** 2026-09-10
- **Apply:** https://job-boards.greenhouse.io/loyal36/jobs/5418623008

## Job description

## About Loyal

Loyal is a clinical-stage veterinary medicine company developing longevity drugs for dogs. Our mission is to help dogs live longer, healthier lives.

We're pioneering a new category of veterinary prescription drugs that proactively and preventatively target the underlying drivers of aging, delaying the onset of disease and preserving quality of life as dogs age. We've already made significant progress in our mission to develop the first FDA-approved drugs to extend canine lifespan: as of early 2026 we've completed two of three major FDA review sections for our lead program, LOY-002, and are targeting submission of the third and final section later this year.

Loyal is a [well-funded startup](https://loyal.com/posts/100m-for-first-longevity-drug) with teams of scientists, veterinarians, engineers, operators, and creatives. You'll help us continue on our path of earning FDA approval for the first lifespan extension medicine for any species, and change what's possible for the dogs we love.

## About the role

We're seeking a Senior Statistician to join the Stats & Data Science team at Loyal, taking independent ownership of our preclinical statistical portfolio – study design and power analysis, aging biomarker analytics, efficacy, target discovery, and dose and mortality modeling. Your work will directly support drug development decisions and the scientific foundation behind Loyal's path to FDA CVM approval for the first lifespan extension medicine for any species.

This role requires more than executing pre-specified analyses. You'll need to think critically about the data itself – questioning whether an endpoint is well-defined, whether a proposed target holds up statistically, and exploring open-ended questions where the right method isn't obvious. Omics is one such exploratory area we're looking to build out, using differential abundance and pathway-level analysis to facilitate target and pathway discovery.

This is a role for someone senior enough to operate independently: leading preclinical statistical strategy and analysis end-to-end and serving as the statistical point of contact for R&D programs. You'll partner closely with R&D scientists and the broader Stats & Data Science team, and will have the opportunity to grow into supporting clinical biostatistics work over time.

You will be reporting to our Statistics Manager, Research.

## Your daily work will include

- Independently leading statistical design and analysis for preclinical studies: dose-response and mortality projection modeling, aging biomarker studies, enrollment/attrition and survival modeling
- Building and applying population PK/PD models (nonlinear mixed-effects, exposure-response relationships) to support internal dose-justification and formulation decisions, extending the team's existing bioequivalence/crossover work
- Conducting exploratory analyses to support endpoint development and target/pathway discovery – thinking critically about what the data can and can't support, not just executing pre-specified analysis plans
- Serving as statistical point of contact for preclinical studies and cross-functional R&D projects, coordinating directly with scientists and program leads
- Applying survival analysis, longitudinal/mixed-effects modeling, and simulation-based power/sample size methods across preclinical programs
- Creating and contributing to internal documentation and reproducible reporting (Quarto/Rmarkdown) for preclinical analyses
- Supporting clinical biostatistics: assisting with SAP development, sitting in on regulatory strategy discussions, and drafting analysis sections for review by the Statistics Manager
- Cross-functional relationships – partnering with Statisticians, Clinicians, and Scientists to support CVM/FDA-ready data strategies and analysis outputs.
- Mentoring junior statisticians on the team
- Peer-reviewing methodology from external consultants, manuscripts, and cross-functional deliverables for statistical rigor
- Identifying opportunities to improve statistical workflows, tooling, or methods across the preclinical portfolio

## About you

- MS or PhD in Statistics, Biostatistics, Pharmacometrics, or a related field
- 8+ years of relevant statistical experience, with a demonstrated track record operating independently on a preclinical or translational statistics portfolio
- Hands-on population PK/PD modeling experience (WinNonLin, NONMEM, nlmixr2, Monolix, or equivalent) – nonlinear mixed-effects models, exposure-response analysis
- Demonstrated experience in experimental design, survival/longitudinal analysis, and post-hoc statistical analysis
- A track record of exploratory, hypothesis-generating analysis – not just confirmatory statistics – with comfort sitting with ambiguous data and pushing back on poorly defined endpoints or targets
- Strong attention to detail and ability to adhere to regulatory requirements
- Demonstrated ability to learn new statistical methods, tools, or scientific domains independently, without needing structured training
- Strong writing and communication skills, including to non-statistical audiences
- Fluency in R and/or Python; experience with Rmarkdown/Quarto or Jupyter for reproducible reporting
- Fluency in AI tools (e.g., Claude code)
- Nice to have: prior work in veterinary, animal health, or translational aging research; experience with data validation pipelines; exposure to regulatory-facing statistical writing (FDA/CVM/EMA); interest in growing into clinical trial biostatistics over time
- Excited about working at the forefront of a new category of veterinary medicine

Salary range: $107,000 - 164,000

Loyal benefits

- Full-coverage health insurance – medical, dental and vision – for you and your dependents
- $1,000 home office equipment stipend
- $1,200/year learning budget for books, courses, etc.
- $250/month wellness budget for gym, cleaners, spa, food, etc.
- All 3-day weekends are turned into 4-day weekends 🎉
- Unlimited vacation and paid holidays
- Paw-ternity leave – adopt a dog and get a day off with your new family member 🐶
- Competitive salary
- Company equity options grant for new hires

Loyal is founded and led by a first-gen female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law.

## Our values

Lean into moonshots

We don't settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have.

Opportunity is at the intersection

We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos.

Expertise without ego

Titles do not determine who has a voice. We work on hard technical problems and have a ton of fun while at it.

Learning by doing

Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes.

Lead with context

We value leading with context. We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. We empower teams to succeed.

Empathy and respect for all life

Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.

## About Loyal

## Company Overview
- **One-liner**: Loyal is a clinical-stage veterinary medicine company developing the first FDA-approved drugs intended to extend the lifespan and healthspan of dogs.
- **Entity Type**: Private (Series C)
- **Headquarters**: San Francisco, California, United States
- **Founded**: 2020
- **Founders**: Celine Halioua

## Core Business
- **Primary industry**: Veterinary Medicine / Animal Health Biotechnology
- **Target customers**: B2B (veterinary clinics) and B2C (dog owners)
- **Mission**: To help dogs live longer, healthier lives by developing drugs that target the underlying processes of aging.

## Products & Services
For each major offering:
- **[LOY-002](https://loyal.com)**: A once-daily pill targeting age-associated metabolic dysfunction in senior dogs (ages 10+, 14+ lb). It is the lead drug program and has completed the second of three major requirements for FDA conditional approval. Designed to extend lifespan and maintain quality of life.
- **[LOY-001](https://loyal.com)**: A drug program targeting age-associated metabolic dysfunction (currently in earlier stages of development).
- **Loyal Learning Hub**: A free library of RACE-approved continuing education courses for veterinary teams to improve care for senior dogs.

## Market Standing
- **Valuation/Market Cap**: Not disclosed
- **Total Funding**: $238.0M across six rounds
  - Series C (2026-02-01): $100M [LinkedIn](https://www.linkedin.com/company/loyalfordogs)
  - Series B (2025-02-01): $22M
  - Series B (2024-03-01): $45M
  - Series A (2022-04-01): $13M
  - Series A (2021-09-01): $27M
- **Key Metric**: Annual Revenue of $2.0M (pre-commercial stage) [LinkedIn](https://www.linkedin.com/company/loyalfordogs)
- **Notable Investors/Partners**: 2 investors in Series B (2025), 3 investors in Series C (2026) [LinkedIn](https://www.linkedin.com/company/loyalfordogs)
- **Growth Signals**: Headcount grew 53.3% year-over-year to 71 employees [LinkedIn](https://www.linkedin.com/company/loyalfordogs). Targeting commercial launch of LOY-002 in 2027. Completed 2/3 major FDA review sections for LOY-002 as of early 2026 [Greenhouse](https://job-boards.greenhouse.io/loyal36/jobs/5235415008).

## Competitive Advantages
- **First-to-market**: Pioneering the first FDA-approved lifespan extension drug for any species, creating a new category in veterinary prescription medicine.
- **Regulatory moat**: Achieving FDA conditional approval for a longevity drug is an extremely difficult technical and regulatory pursuit, creating a significant barrier to entry.
- **Targeting aging itself**: Unlike most veterinary drugs that treat specific diseases, Loyal targets the underlying drivers of aging to delay the onset of multiple age-related conditions.
- **Strong clinical trial infrastructure**: 70 veterinary clinics enrolled in the STAY clinical trial, with over 1,317 dogs accepted [loyal.com](https://loyal.com).

## Strategic Focus
- **Regulatory approval**: Completing the third and final FDA review section for LOY-002 and targeting submission in late 2026 [Greenhouse](https://job-boards.greenhouse.io/loyal36/jobs/5235415008).
- **Commercial launch preparation**: Scaling the company from ~70 to ~150 people, building a customer service organization, and leading product distribution platform buildout for prescription drug distribution, targeting a 2027 launch [Greenhouse](https://job-boards.greenhouse.io/loyal36/jobs/5235415008).
- **AI-leveraged efficiency**: Deploying AI tooling across operations, finance, recruiting, and customer service to scale leverage with the team [Greenhouse](https://job-boards.greenhouse.io/loyal36/jobs/5235415008).
- **Pipeline expansion**: Developing a portfolio of three drug programs (LOY-002, LOY-001, and others) targeting different aspects of aging.

## Why Work Here
- **Mission-driven**: The company is deeply committed to helping dogs live longer, healthier lives — a compelling purpose for many job seekers.
- **Culture**: Values include "Empathy and respect for all life," "Expertise without ego," "High agency, high humility," and "Lead with transparency and context" [loyal.com/careers](https://loyal.com/careers).
- **Remote-first**: All open roles are listed as "Remote - US" [Greenhouse](https://job-boards.greenhouse.io/loyal36).
- **Generous benefits** [loyal.com/careers](https://loyal.com/careers):
  - Full-coverage health insurance (medical, dental, vision) for you and dependents
  - $1,000 home office equipment stipend
  - $1,200/year learning budget
  - $250/month wellness budget (gym, cleaners, spa, food)
  - All 3-day weekends turned into 4-day weekends
  - Unlimited vacation and paid holidays
  - "Paw-ternity leave" — adopt a dog and get a day off
  - Annual company retreat at beautiful locations (recently: Tahoe, Cape Cod)
  - Competitive salary and equity options grant
- **Leadership**: Founded and led by a first-gen female CEO, Celine Halioua. The company is an equal opportunity employer.
- **Growth opportunity**: As a well-funded startup targeting a 2027 commercial launch, there is significant potential for career growth and impact.

## Sources
1. [loyal.com](https://loyal.com)
2. [loyal.com/careers](https://loyal.com/careers)
3. [LinkedIn - Loyal](https://www.linkedin.com/company/loyalfordogs)
4. [Greenhouse - Loyal Jobs](https://job-boards.greenhouse.io/loyal36)
5. [Greenhouse - COO Job Posting](https://job-boards.greenhouse.io/loyal36/jobs/5235415008)

## Other roles at Loyal

- [Director, FP&A](https://feeny.ai/job/director-fp-a-loyal-united-states-nb572c2e9bfg) — United States
- [Senior Associate Specialist, Regulatory Operations](https://feeny.ai/job/senior-associate-specialist-regulatory-operations-loyal-united-states-bd9kwj4pttpt) — United States
- [Principal Analytical QA Specialist, Drug Substance](https://feeny.ai/job/principal-analytical-qa-specialist-drug-substance-loyal-united-states-hva9wqft24jn) — United States
- [Senior Principal Scientist, Drug Substance](https://feeny.ai/job/senior-principal-scientist-drug-substance-loyal-united-states-6fv71bjzb5w0) — United States
- [Director, Regulatory Affairs - Clinical](https://feeny.ai/job/director-regulatory-affairs-clinical-loyal-united-states-1j9et5dxrqdn) — United States