---
title: 'Senior Systems Engineer, IVD Software at Veracyte'
canonical: 'https://feeny.ai/job/senior-systems-engineer-ivd-software-veracyte-south-san-francisco-california-tdfe8mhkdyj0'
type: 'job'
last_seen: '2026-09-05'
---

# Senior Systems Engineer, IVD Software at Veracyte

- **Company:** Veracyte
- **Location:** South San Francisco California, United States
- **Compensation:** $183k–$225k
- **Posted:** 2026-06-12
- **Last confirmed live:** 2026-09-05
- **Apply:** https://veracyte.com/job-detail?gh_jid=5146940007

## Job description

At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe. Working at Veracyte enables our employees to not only make a meaningful impact on the lives of patients, but to also learn and grow within a purpose driven environment. This is what we call the Veracyte way – it’s about how we work together, guided by our values, to give clinicians the insights they need to help patients make life-changing decisions.

Our Values:

- We Seek A Better Way: We pursue bold ideas, embrace complexity, and keep pushing forward.
- We Make It Happen: We act with urgency, deliver with excellence, and always find a way.
- We Are Stronger Together: We engage with empathy, align around what's best for Veracyte, and celebrate as one team.
- We Care Deeply: We show up with integrity, kindness, and respect for one another.

The Position:

The Sr. Systems Engineer is a senior individual contributor and recognized technical authority responsible for the system architecture, reliability, and long-term operability of a commercial in vitro diagnostic (IVD) software product deployed across diverse customer environments. This role is focused exclusively on customer-facing product systems, not internal enterprise IT, and requires deep expertise in Windows-based platforms, distributed systems, and hybrid infrastructure.

At the Senior level, this role is expected to operate with broad autonomy and influence, proactively identifying systemic risks, anticipating environment-specific failure modes, and shaping system design decisions early in the product lifecycle. You will partner closely with software engineering, quality, DevOps, and product teams to ensure the product behaves safely, predictably, and reliably across development, validation, and real-world enterprise deployments.

## Responsibilities

- Own and evolve the system-level architecture of a Windows-based IVD software product deployed to customer environments.
- Act as a system-level technical authority, influencing architecture and design decisions without formal people management.
- Design, configure, and support product deployments using IIS, SQL Server, WSL, and Docker across on-premises, virtualized, and cloud environments.
- Anticipate, identify, and mitigate environment-specific risks across Windows and Linux systems, virtual machines, containers, networking, and cloud infrastructure.
- Support and stabilize a distributed product maintained over multiple years across a large enterprise install base (100+ customer installations).
- Lead deep root-cause analysis of complex issues spanning application behavior, operating systems, databases, containers, and infrastructure.
- Define, document, and enforce supported deployment models, environment assumptions, constraints, and known failure modes.
- Partner early with software engineering to surface non-obvious system dependencies, scalability limits, and operational risks.
- Contribute to containerized and orchestrated deployment strategies; experience with ECS or Kubernetes is a plus.
- Influence CI/CD pipelines and release processes to improve reliability, repeatability, and diagnosability in regulated environments.
- Apply security best practices to product systems, including hardening, access control, patching strategies, and vulnerability management.
- Drive improvements in observability through logging, monitoring, diagnostics, and operational tooling.
- Develop and maintain automation scripts to reduce manual configuration, increase consistency, and eliminate classes of environment-related issues.
- Ensure system designs, configurations, and documentation meet IVD regulatory and quality expectations.
- Create and maintain system architecture documentation, deployment guides, and operational playbooks.
- Serve as a senior escalation point and mentor for system-level issues, raising the bar for system engineering practices.

Who You Are:

- Bachelor’s degree in Computer Science, Engineering, or a related field, or equivalent practical experience.
- A minimum of 6 – 7 years of experience supporting commercial product software.
- Deep hands-on experience with Windows Server environments, including IIS and SQL Server in production.
- Strong working knowledge of Linux systems (e.g., Ubuntu, RHEL-based distributions) in product deployments.
- Proven experience with Docker and containerized application deployments.
- Experience supporting products deployed across virtualized environments (VMware, Hyper-V) and cloud infrastructure.
- Hands-on experience with AWS services such as EC2, VPC, IAM, and storage services.
- Demonstrated ability to proactively diagnose and resolve complex system-level issues across software, OS, and infrastructure layers.
- Experience developing automation scripts using Bash, PowerShell, Python, or similar languages.
- Familiarity with CI/CD pipelines and release workflows in regulated or quality-focused environments.
- Strong troubleshooting, problem-solving, and communication skills.

## Preferred Qualifications

- Direct experience supporting IVD, medical device, or other regulated software products.
- Experience maintaining a distributed product for 2–3 years across 100+ enterprise customer installations.
- Exposure to container orchestration platforms such as ECS, EKS, or Kubernetes.
- Experience with infrastructure as code or configuration management tools.
- Familiarity with monitoring and logging platforms and operational diagnostics.
- Background in regulated environments with awareness of compliance and audit expectations.
- Demonstrated ability to influence system architecture and technical direction at a product level without formal management responsibility.

#LI-Hybrid

The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to years of experience, skillset, geographic location, industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives, and restricted stock units.

Pay range $183,000—$225,000 USD

## What We Can Offer You

Veracyte is a growing company that offers significant career opportunities if you are curious, driven, patient-oriented and aspire to help us build a great company. We offer competitive compensation and benefits, and are committed to fostering an inclusive workforce, where diverse backgrounds are represented, engaged, and empowered to drive innovative ideas and decisions. We are thrilled to be recognized as a 2024 Certified™ Great Place to Work® in both the US and Israel - a testament to our dynamic, inclusive, and inspiring workplace where passion meets purpose.

## About Veracyte

Veracyte (Nasdaq: VCYT) is a global diagnostics company whose vision is to transform cancer care for patients all over the world. We empower clinicians with the high-value insights they need to guide and assure patients at pivotal moments in the race to diagnose and treat cancer. Our Veracyte Diagnostics Platform delivers high-performing cancer tests that are fueled by broad genomic and clinical data, deep bioinformatic and AI capabilities, and a powerful evidence-generation engine, which ultimately drives durable reimbursement and guideline inclusion for our tests, along with new insights to support continued innovation and pipeline development. For more information, please visit [www.veracyte.com](https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.veracyte.com%2F&esheet=54340020&newsitemid=20251015446872&lan=en-US&anchor=www.veracyte.com&index=5&md5=4d48386b00ece1531372e2e593d7cd2d) or follow us on [LinkedIn](https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fveracyte%2F&esheet=54340020&newsitemid=20251015446872&lan=en-US&anchor=LinkedIn&index=6&md5=234cba826cb637f449d2722139f551ef) or https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fx.com%2Fveracyte%3Fs%3D11&esheet=54340020&newsitemid=20251015446872&lan=en-US&anchor=X+%28Twitter%29&index=7&md5=20ead95735af622bf261b20735515b66.

Veracyte, Inc. is an Equal Opportunity Employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status or disability status. Veracyte participates in E-Verify in the United States. View our [CCPA Disclosure Notice](https://www.veracyte.com/legal/privacy-statement-for-california-residents/)

If you receive any suspicious alerts or communications through LinkedIn or other online job sites for any position at Veracyte, please exercise caution and promptly report any concerns to careers@veracyte.com

## About Veracyte

## Company Overview
- **One-liner**: Veracyte is a global cancer diagnostics company that develops molecular tests to help clinicians make more informed care decisions by analyzing the unique biology of each patient’s tumor.
- **Entity Type**: Public (traded on NASDAQ; ticker not explicitly confirmed in provided sources)
- **Headquarters**: South San Francisco, California, United States (with additional high-complexity clinical labs in San Diego, California, and Austin, Texas)
- **Founded**: Not publicly available in provided sources
- **Founders**: Not publicly available in provided sources

## Core Business
- **Primary industry**: Cancer diagnostics / molecular genomics / precision oncology
- **Target customers**: B2B – clinicians, hospitals, health systems, and laboratory service providers; B2C indirectly through patient care decisions
- **Mission statement**: “Transform cancer care for patients all over the world” (from about page)

## Products & Services
- **Afirma Genomic Sequencing Classifier**: A test for thyroid nodules to help avoid unnecessary surgery (SaaS/Service)
- **Decipher Prostate Genomic Classifier**: The only gene expression test included in the NCCN Clinical Practice Guidelines for prostate cancer (Service)
- **Decipher Bladder Genomic Classifier**: A test for bladder cancer to guide treatment decisions (Service)
- **Prosigna Breast Risk of Recurrence (ROR) Test**: Recently launched commercially in the U.S. (June 2026) to identify high-risk breast cancer patients who may safely avoid chemotherapy (Service)
- **TrueMRD Monitoring Test for MIBC**: Minimal residual disease monitoring for muscle-invasive bladder cancer; secured Medicare coverage in May 2026 (Service)
- **Provider Ordering Portal**: Digital platform for clinicians to order Veracyte tests (SaaS)
- **Scientific Publications & Evidence Engine**: AI-assisted data mining, multimodality analysis, and bioinformatics to support ongoing test development (R&D platform)

## Market Standing
- **Valuation/Market Cap**: Not publicly available in provided sources (public company; financial specifics not included in searched materials)
- **Key Metric**: Over 900,000 patients have benefited from Veracyte’s genomic tests across multiple cancer types; more than 600 peer-reviewed publications validate the platform’s clinical utility
- **Notable Investors/Partners**: NCCN (Decipher Prostate included in guidelines); collaborators on landmark OPTIMA trial (Prosigna); Medicare (coverage for TrueMRD)
- **Growth Signals**:
  - Commercial launch of Prosigna in the U.S. (June 2026)
  - Medicare coverage for TrueMRD monitoring test (May 2026)
  - Three high-complexity clinical labs operating in San Diego, South San Francisco, and Austin
  - Headcount of over 800 team members serving clinicians and patients globally
  - Landmark OPTIMA trial results published, demonstrating Prosigna’s ability to identify patients who can safely avoid chemotherapy

## Competitive Advantages
- **Evidence depth**: Only gene expression test included in NCCN Guidelines for prostate cancer; >600 peer-reviewed publications
- **Multi-cancer portfolio**: Covers thyroid, prostate, breast, bladder, and lung cancer, offering a comprehensive platform for oncology decision-making
- **Regulatory & reimbursement momentum**: Recent Medicare coverage for TrueMRD and U.S. commercial launch of Prosigna demonstrate market adoption
- **Integrated platform**: Combines genomics, transcriptomics, real-world data, and AI-driven analysis to continuously generate evidence and refine tests

## Strategic Focus
- **Geographic and product expansion**: Commercializing the Prosigna test in the U.S. and expanding reimbursement for monitoring tests like TrueMRD
- **Real-world evidence generation**: Using their evidence engine (AI, multimodal analysis, bioinformatics) to support new indications and clinical utility
- **Platform scalability**: Building a robust diagnostics platform that can be applied to additional cancer types and clinical questions
- **Clinical trial partnerships**: Leveraging studies like OPTIMA to validate clinical value and drive guideline inclusion

## Why Work Here
- **Culture**: Values-driven (“We care deeply,” “We seek a better way,” “We make it happen,” “We are stronger together”); recognized as a Great Place to Work® and listed on Forbes Mid-Cap list
- **Work model**: Hybrid/remote options available; positions in labs, offices, field locations, and remote work (as seen on careers page)
- **Benefits** (U.S. examples): Medical, dental, vision, mental health support, paid time off, parental leave, 401(k) with employer match, employee stock purchase plan (ESPP), tuition reimbursement, commuter benefits, Calm app subscription, gym reimbursement, and family care support
- **Mission-driven**: Opportunity to directly impact cancer patients’ lives by developing and delivering diagnostic tests that provide clearer answers for clinicians
- **Growth opportunities**: Roles span research, clinical development, bioinformatics, lab services, regulatory affairs, data engineering, and more

## Sources
1. [Veracyte Home Page](https://www.veracyte.com/)
2. [Veracyte About Page](https://www.veracyte.com/company/about-veracyte/)
3. [Veracyte Careers Page](https://www.veracyte.com/company/careers/)
4. [Veracyte Working at Veracyte Page](https://www.veracyte.com/company/working-at-veracyte/)
5. [Veracyte LinkedIn Profile](https://www.linkedin.com/company/veracyte)

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