--- title: 'Sr. Bioengineer, Preclinical Development (In Vivo) at Pulse Biosciences' canonical: 'https://feeny.ai/job/sr-bioengineer-preclinical-development-in-vivo-pulse-biosciences-hayward-67znvpva2sf0' type: 'job' last_seen: '2026-09-13' --- # Sr. Bioengineer, Preclinical Development (In Vivo) at Pulse Biosciences - **Company:** Pulse Biosciences - **Location:** Hayward, CA - **Work type:** onsite - **Posted:** 2026-07-31 - **Last confirmed live:** 2026-09-13 - **Apply:** https://job-boards.greenhouse.io/pulsebiosciences/jobs/5370273008 ## Job description Pulse Biosciences (Nasdaq: PLSE): Join the Future of Bioelectric Medicine Pulse Biosciences is a novel bioelectric medicine company committed to health innovation that has the potential to improve the quality of life for patients.  The Company’s proprietary CellFX® nsPFA™ (nanosecond Pulsed Field Ablation) technology delivers nanosecond pulses of electrical energy to non-thermally ablate cells while sparing adjacent noncellular tissue. The Company is actively pursuing the development of its CellFX nsPFA technology for use in the surgical treatment of atrial fibrillation and percutaneously in a select few other markets where it could have a profound positive impact on healthcare for both patients and providers. Visit [pulsebiosciences.com](https://cts.businesswire.com/ct/CT?id=smartlink&url=http%3A%2F%2Fpulsebiosciences.com%2F&esheet=53299490&newsitemid=20230202005390&lan=en-US&anchor=pulsebiosciences.com&index=2&md5=be5397cf42a2c83df28cd007fa26f3d9) to learn more. Why Join Us? At Pulse Biosciences, we are driven by purpose and innovation. - Our Mission: To build a viable Company that designs, produces, and commercializes nano-pulse technology to improve and extend the lives of patients. To solve the needs of patients, physicians, and healthcare providers with high quality and high reliability products and services, developed in accordance with rigorous scientific, engineering, and clinical standards.  We exist to make a positive difference in the lives of patients, physicians, healthcare providers, shareholders and our Pulse Biosciences team members. - Our Culture: A community of creative, forward-thinking individuals tackling challenges with ingenuity and collaboration. - Our Commitment: Hiring the best and brightest minds to advance our world-class organization. What You Will Experience: - Culture and Purpose - Purposeful and rewarding work collaborating with bright and curious minds brings us together! - Innovative Environment - An environment that fosters innovation to take products from concept to human use quickly! - Growth Opportunities - Learning culture focusing on professional and personal growth and development that you can only get in a startup-like environment! - Comprehensive Benefits - A variety of health insurance plans and supplemental insurance options, and 401k retirement savings plan. - Ownership and Rewards - Stock options awards and Employee Stock Purchase Plan (ESPP) to share in our success. - Work-Life Balance - Enjoy paid time off, paid holidays, flexible work schedule and wellness program, including onsite gym and mindfulness classes. - Diversity & Inclusion - A commitment to providing a respectful work environment to our diverse workforce. ## About the Role The Sr. Bioengineer of Preclinical Development is a key technical contributor responsible for independently executing complex preclinical studies, developing experimental models, and supporting engineering and scientific initiatives that advance the CellFX® nsPFA platform. This role leads portions of preclinical programs, troubleshoots technical challenges, and provides engineering insight that informs device design, treatment algorithms, and clinical strategy. This role mentors junior staff, supports cross‑functional teams, and contributes to the generation of high‑quality scientific and engineering evidence. To Make an Impact, You Will: - Lead execution of preclinical studies, including protocol development, experimental design input, data collection, and report authorship. - Develop and refine benchtop, ex vivo, and in vivo models to support engineering and scientific objectives. - Troubleshoot technical issues related to devices, instrumentation, and experimental workflows. - Analyze engineering and biological data to generate insights that inform product development. - Support design engineers with device testing, verification activities, and treatment parameter optimization. - Maintain and improve histology and tissue‑processing workflows; ensure data integrity and traceability. - Mentor Associate and Engineer‑level staff in laboratory techniques, data analysis, and documentation. - Collaborate with Clinical, Regulatory, and Engineering teams to support evidence generation for regulatory submissions and clinical programs. - Prepare technical presentations and documentation for internal and external stakeholders. - Manage vendor relationships related to histology, imaging, and preclinical services. - Mentor junior staff and contribute to team development. To Excel, You Will Bring: - Bachelor’s Degree with 5+ years of experience or Master’s Degree 3+ years of experience in Bioengineering, Biomedical Engineering, Biology, or related field. - Strong understanding of anatomy, imaging, surgical workflows, tissue processing, and histology. - Experience with energy‑based delivery systems is preferred. - Experience supporting preclinical or translational research required. - Startup experience preferred. - Proficient knowledge and skill in Microsoft Office Suite applications. - Strong analytical, problem‑solving, and experimental design skills. - Strong communication skills, including technical writing and data presentation. - Ability to independently execute complex preclinical studies. - Ability to manage multiple priorities in a dynamic environment. - Ability to independently execute complex preclinical studies. - Ability to work as a team member, multi-task and be very flexible to adapt to the ever-changing work priorities and requirements of a dynamic, fast growing company. - Ability to travel up to 25% of the time, including overnight travel may be required. - Ability to lift 25 pounds. Pay Range: Compensation is determined based on a wide range of factors including location, job-related skills, experience, education, and training. It is not typical for an individual to be hired at or near the top of the range for their role. This pay range is specific to Northern California location. Base salary range: $135K-$155K. This position is located onsite in Hayward, CA and candidates must reside in the San Francisco Bay Area. No relocation offered. Ready to Shape the Future of Healthcare? Apply today to join Pulse Biosciences and help us redefine the boundaries of medicine with bioelectric innovation.  To learn more about us, visit our website at [www.pulsebiosciences.com](http://www.pulsebiosciences.com). We provide equal employment opportunities (EEO) to all persons regardless of race, age, color, gender, sexual orientation, national origin, physical or mental disability, religion, or any other characteristic protected by federal, state or local law. We will make reasonable accommodations for qualified individuals with disabilities. PRINCIPALS ONLY; UNSOLICITED CANDIDATE SUBMISSIONS FROM RECRUITERS OR THIRD-PARTY AGENCIES WILL BE CONSIDERED FREE REFERRALS. ## About Pulse Biosciences ## Company Overview - **One-liner**: Pulse Biosciences is a bioelectric medicine company developing and commercializing its proprietary Nanosecond Pulsed Field Ablation (nsPFA) technology for nonthermal ablation of soft tissue, with initial applications in dermatology and expanding into cardiac electrophysiology and thyroid nodule treatment. - **Entity Type**: Public (ticker symbol not specified in provided search results; company maintains an investor relations page and files SEC reports). - **Headquarters**: Hayward, CA (derived from job listings showing Hayward addresses). - **Founded**: Not publicly available in provided sources. - **Founders**: Not publicly available in provided sources. ## Core Business - **Primary industries**: Medical devices, bioelectric medicine, electrophysiology, dermatology, and interventional cardiology. - **Target customers**: B2B – hospitals, clinics, and physicians (electrophysiologists, cardiologists, dermatologists, and surgeons). - **Mission**: “To build a viable Company that designs, produces, and commercializes nano-pulse technology to improve and extend the lives of patients.” (source: [pulsebiosciences.com/about-us](https://www.pulsebiosciences.com/about-us/)) ## Products & Services - **CellFX® nsPFA System** – The first commercial product harnessing nsPFA energy for dermatologic conditions (e.g., clearing cells nonthermally). Multi-application platform with a utilization-based revenue model. Used to treat over 6,000 patients outside of cardiology. - **nPulse™ Vybrance™ Percutaneous Electrode** – An investigational device for nonthermal ablation of benign thyroid nodules. First-in-human clinical study results presented at the 2024 NASIT Annual Meeting; 30 patients treated. Not yet cleared by FDA. - **CellFX® nsPFA™ 360 Cardiac Catheter** – Catheter-based system for atrial fibrillation (AF) ablation. First-in-human feasibility study of 150 patients showed rapid procedure times and minimal adverse effects, presented at the 31st Annual AF Symposium (Feb 2026). - **CellFX® nsPFA™ Cardiac Clamp** – A surgical cardiac ablation device designed to produce continuous linear transmural ablations. Submitted for 510(k) clearance to the FDA. - **nsPFA™ Generator Platform** – A versatile generator that connects to multiple applicator types (superficial, surgical, catheter-based), supporting the company’s pipeline. ## Market Standing - **Valuation/Market Cap**: Not disclosed in provided search results. - **Key Metric**: Over 6,000 patients treated safely and effectively outside of cardiology (source: [pulsebiosciences.com/technology](https://www.pulsebiosciences.com/technology/)). - **Notable Investors/Partners**: Not explicitly named in provided materials; the company has a deep IP portfolio and partnerships with clinical leaders such as Dr. Vivek Reddy (Mount Sinai Fuster Heart Hospital, NY). Board appointments include Maria Sainz (President & CEO of Hyperfine, Inc.) and Dr. David Kenigsberg (Chief Medical Officer of Electrophysiology). - **Growth Signals**: - Two 510(k) submissions to the FDA (Cardiac Clamp and Percutaneous Electrode) filed in 2025/2026. - First-in-human data for the Cardiac Catheter (150 patients) presented at major symposium; positive 60-day follow-up results from an early cohort. - Expansion from dermatology into cardiac and thyroid indications. - Over 130 issued patents globally (source: [pulsebiosciences.com/about-us](https://www.pulsebiosciences.com/about-us/)). ## Competitive Advantages - **Proprietary nsPFA technology** – Nonthermal mechanism spares noncellular tissue, offering potential safety benefits over thermal ablation. - **Broad IP moat** – Over 130 issued patents globally provide strong defensibility. - **Multi-application platform** – The nsPFA generator can be paired with different applicators, enabling entry into multiple large markets (dermatology, cardiac surgery, electrophysiology, thyroid). - **Clinical validation** – Demonstrated safety and efficacy in >6,000 patients across non-cardiac uses, plus promising cardiac first-in-human data. ## Strategic Focus - Securing FDA clearances for the cardiac clamp and percutaneous electrode (510(k) submissions underway). - Advancing the cardiac catheter program toward pivotal studies and commercialization. - Expanding the pipeline of nsPFA applications into additional therapy areas (e.g., other soft tissue ablations). - Growing the IP portfolio and extending the platform’s reach into surgical and interventional settings. ## Why Work Here - **Culture**: The company describes itself as “best suited for individuals who are creative, forward‑thinking and who approach challenges with an innovative attitude” (source: [job-boards.greenhouse.io/pulsebiosciences](http://job-boards.greenhouse.io/pulsebiosciences)). - **Work arrangements**: Roles are offered in Hayward, CA; some positions are hybrid (e.g., Patent Agent, Sr. Manager Technical Accounting) and others are onsite (e.g., Sr. Quality Engineer, Manager Electrical Engineering). - **Impact**: Employees work on a novel bioelectric medicine platform with the potential to change standard of care in cardiac and soft tissue ablation – directly improving patient outcomes. - **Team**: “Top experts in pulsed electric field technologies with a broad range of engineering expertise across multiple medical device domains.” (source: [pulsebiosciences.com/about-us](https://www.pulsebiosciences.com/about-us/)) ## Sources 1. [pulsebiosciences.com](https://www.pulsebiosciences.com/) – Main corporate site and latest news 2. [pulsebiosciences.com/about-us](https://www.pulsebiosciences.com/about-us/) – About Us, mission, and IP 3. [pulsebiosciences.com/technology](https://www.pulsebiosciences.com/technology/) – Technology description and patient data 4. [investors.pulsebiosciences.com](https://investors.pulsebiosciences.com/) – Investor relations (public company presence) 5. [job-boards.greenhouse.io/pulsebiosciences](http://job-boards.greenhouse.io/pulsebiosciences) – Careers page and job listings ## Other roles at Pulse Biosciences - [Sr. Clinical Research Associate (Cardiac Catheter Products)](https://feeny.ai/job/sr-clinical-research-associate-cardiac-catheter-products-pulse-biosciences-fn14sg07jk2a) — United States - [Sr. Clinical Research Associate (Soft Tissue Ablation)](https://feeny.ai/job/sr-clinical-research-associate-soft-tissue-ablation-pulse-biosciences-united-8hqypfxjpffh) — United States - [Sr. Project Manager, Electrical Engineering](https://feeny.ai/job/sr-project-manager-electrical-engineering-pulse-biosciences-hayward-tx1dxmwed5wj) — Hayward, CA