---
title: 'Sr. Scientist, Downstream Process Development at GenScript/ProBio'
canonical: 'https://feeny.ai/job/sr-scientist-downstream-process-development-genscript-probio-united-states-a2qsx1dhjcv8'
type: 'job'
last_seen: '2026-09-08'
---

# Sr. Scientist, Downstream Process Development at GenScript/ProBio

- **Company:** GenScript/ProBio
- **Location:** United States
- **Posted:** 2026-08-21
- **Last confirmed live:** 2026-09-08
- **Apply:** https://job-boards.greenhouse.io/genscript/jobs/5218660007

## Job description

## About GenScript

Founded in 2002 in New Jersey, GenScript Biotech Corporation accelerates innovation in biotech and healthcare by providing researchers and companies with the building blocks needed to develop groundbreaking treatments and products. Guided by its mission to Make People and Nature Healthier Through Biotechnology, and its role as a well-recognized biotechnology company, GenScript has a team of approximately 6,165 employees and has served more than 200,000 customers across over 100 countries and regions.

About ProBio:

ProBio, a subsidiary of GenScript, is a global CDMO offering end-to-end services from discovery to GMP for plasmids, antibodies, and cell & gene therapies. We bring together multidisciplinary expertise to accelerate development and manufacturing through customized, and comprehensive services. ProBio has established companies in the United States, the Netherlands, South Korea, and China (Hong Kong, Shanghai, and Nanjing) and other regions to serve global customers, and has helped customers in the United States, Europe, Asia Pacific and other regions obtain more than 150 IND approvals since October 2017.

Position Overview:

The position reports to the Associate Director, Downstream Viral Vector Process Development & MSAT Department. This role is ideally suited for a dynamic bench-focused individual to support/lead translation of research process to GMP-compliant manufacturing, and will develop, scale-up, and evaluate the technology transfer of viral vector processes. This is a great opportunity to join a fast-paced company, develop, and expand technical expertise to lead by example and potentially lead a small team in the near future.

Responsibilities:

- Hands-on experimental work in the development and optimization of downstream unit operations (TFF, Affinity/Ion Exchange/multimodal Chromatography, Viral clearance, Sterile filtration, etc.) for viral vector manufacturing process.
- Contribute to the planning, design, and execution of AAV/LVV purification-related experiments to analyze, interpret, and report data summary packages.
- Interact and collaborate with internal/external partnerships to evaluate and implement new bioprocessing technologies and strategies.
- Interact with cross functional teams (Analytic team, MFG, Supply chain, Facility, QA, QC) to support process technology transfer, cGMP risk evaluation, and deviation management.
- Maintain and follow detailed and comprehensive project timelines.
- Support in the preparation of CMC sections for regulatory submissions (IND, Annual Reports, and BLA), invention disclosures, progress reports, and publications.
- Present updates to project or upper management teams on process development and manufacturing support activities.
- Read and understand scientific literature in gene and cell therapy. Use the knowledge to generate ideas and contribute to process design and development.
- Perform other duties as assigned based on business needs.

Qualifications:

- Master’s or Ph.D. degree with 5+ years’ relevant industry experience in Chemical/Biochemical Engineering, Biological Sciences, or a related scientific discipline in biotech development with particular experience in gene and cell therapy product design. Experience with LVV and AAV process development is a plus.
- Previous experience in viral vector process development and manufacturing is highly preferred.
- Strong understanding of process scale-up and scale-down modeling.
- Good understanding of Design of Experiment (DOE) and statistical analysis.
- Experience in CMC regulatory affairs for FDA, and EMA is a plus.
- Strong organizational skills and detailed documentation abilities are required.
- Work independently in hands-on laboratory setting, self-motivated to learn and develop new techniques.
- Strong interpersonal, verbal, and written communication skills.
- Results oriented, be able to effectively prioritize and complete tasks on time.
- Collaboration and teamwork.

Pay range is estimated between $100k - $130k based on skill set and experience.

#PB

#LW Benefits:

Benefits include medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and company holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.

Please note: Genscript USA Inc./ProBio Inc. will only contact candidates through verified application sources. GenScript/Probio does not request personal information from candidates through individual email or any other platform.

## About GenScript/ProBio

## Company Overview
- **One-liner**: GenScript Biotech Corporation, through its subsidiary ProBio, provides end-to-end contract development and manufacturing (CDMO) services for biologics, cell and gene therapies, and mRNA innovations, accelerating drug development from discovery to commercialization.
- **Entity Type**: Public (Hong Kong Stock Exchange: 1548.HK)
- **Headquarters**: Piscataway, New Jersey, United States (GenScript HQ); ProBio’s U.S. CDMO center of excellence in Hopewell, New Jersey
- **Founded**: 2002 (GenScript)
- **Founders**: Not publicly listed on provided sources; GenScript was founded by a team of scientists and entrepreneurs.

## Core Business
- **Primary industry/industries**: Biotechnology – Contract Development and Manufacturing Organization (CDMO); Life Science CRO; Cell & Gene Therapy; Biologics; mRNA therapeutics.
- **Target customers**: Biotech and pharmaceutical companies of all sizes (startups to large pharma), academic researchers, and clinical-stage developers – B2B focused.
- **Mission or purpose statement**: “Make People and Nature Healthier Through Biotechnology” (GenScript); ProBio’s mission: “Through our commitment to quality, collaboration and innovation, ProBio delivers customized solutions to transform scientific discoveries into market-ready therapies that make a lasting impact on patients’ health and well-being.”

## Products & Services
- **Plasmid DNA Development & GMP Manufacturing**: Specialized services for cell and gene therapy programs, from early development through clinical and commercial supply, manufactured at the Hopewell, New Jersey facility (FDA-compliant).
- **Viral Vector Development & GMP Manufacturing**: End-to-end support for AAV, lentivirus, and other vectors for clinical and commercial programs.
- **mRNA Development & Manufacturing**: Integrated solutions for speed, scalability, and quality, covering process development and GMP production.
- **Biologics Discovery & Development**: Antibody discovery, engineering, cell line development, upstream/downstream processing, and drug product manufacturing for monoclonal, bispecific, and multi-specific antibodies and recombinant proteins.
- **CMC Services for CGT**: Full CMC support for plasmids, viral vectors, mRNA, and nucleic acid drugs – from IND filing to commercial manufacturing, including cell banking, process characterization, analytical development, and stability studies.
- **Integrated Services**: Process development, bioanalytical development, formulation, and in vitro/in vivo pharmacology.

## Market Standing
- **Valuation/Market Cap**: Not publicly available from provided sources (GenScript is a public company with ticker 1548.HK; market cap varies – check financial platforms for latest).
- **Key Metric**: GenScript employs approximately 6,165 people and has served over 200,000 customers across more than 100 countries. ProBio has helped customers obtain more than 150 IND approvals since October 2017.
- **Notable Investors/Partners**: GenScript is a publicly traded company; ProBio is a wholly owned subsidiary. No specific investor names provided. Key partners include biotech and pharma companies globally.
- **Growth Signals**: Global expansion with facilities in the US, Netherlands, South Korea, and China (Hong Kong, Shanghai, Nanjing). GMP capacity meeting FDA, EMA, and NMPA regulatory standards. Growing network of development and manufacturing sites to support international programs.

## Competitive Advantages
- **End-to-End Platform**: ProBio offers a fully integrated “DNA-to-GMP” platform covering discovery, development, and manufacturing across multiple modalities (plasmids, viral vectors, mRNA, antibodies) – reducing handoffs and risk.
- **Regulatory Expertise**: Facilities designed to meet FDA, EMA, and NMPA requirements, enabling clients to navigate global submissions.
- **Proprietary Technology**: Technology-driven platform processes that minimize variability and accelerate timelines from early development to commercial supply.
- **Proven Track Record**: 150+ IND approvals since 2017 and partnerships with companies of all sizes demonstrate reliability and depth.

## Strategic Focus
- **Current priorities and direction for growth**: Expand global footprint to be closer to customers and align with regional regulatory needs; invest in cutting-edge capabilities for advanced therapies (CGT, mRNA); maintain a customer-centric, innovation-driven culture to accelerate client programs.
- **Key initiatives**: Building out purpose-built facilities for each modality, enhancing proprietary platform processes, and recruiting talent across R&D, manufacturing, and business development.

## Why Work Here
- **Culture highlights**: Mission-driven environment focused on “making people and nature healthier.” Core values: Customer Centric, Innovation, and Integrity. Emphasis on ethical standards, transparency, and collaboration.
- **Remote/hybrid/office policy**: Not explicitly stated in provided sources; roles appear to be based at specific sites (e.g., Hopewell, NJ; Piscataway, NJ; Europe; Asia). Some positions (e.g., Commercial Technical Support Specialist) offer remote in Europe.
- **Notable perks or engineering culture**: Opportunity to work on cutting-edge therapies (gene editing, mRNA, biologics) that directly impact patient health. Global career opportunities across multiple continents. The company encourages “new ideas and challenging traditional approaches” – a strong innovation culture for scientists and engineers.

## Sources
1. [genscriptprobio.com](https://genscriptprobio.com/about-us.html?src=fromgenscriptsubpage)
2. [genscript.com](https://www.genscript.com/our-business.html)
3. [probiocdmo.com](https://www.probiocdmo.com/careers.html)
4. [greenhouse.io](https://job-boards.greenhouse.io/genscript/jobs/4697895007)

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