--- title: 'Sr. Software Engineer - ML Systems at Cleerly' canonical: 'https://feeny.ai/job/sr-software-engineer-ml-systems-cleerly-denver-colorado-2c43mr5x44ys' type: 'job' last_seen: '2026-09-06' --- # Sr. Software Engineer - ML Systems at Cleerly - **Company:** Cleerly - **Location:** Denver Colorado, United States - **Posted:** 2026-04-13 - **Last confirmed live:** 2026-09-06 - **Apply:** https://cleerly.com/careers-board?gh_jid=5967613004 ## Job description ## About Cleerly We’re Cleerly – a healthcare company that’s revolutionizing how heart disease is diagnosed, treated, and tracked. We were founded in 2017 by one of the world’s leading cardiologists and are a growing team of world-class engineering, operations, medical affairs, marketing, and sales leaders. We raised $223M in Series C funding in 2022 which has enabled rapid growth and continued support of our mission. In December 2024 we received an additional $106M in a Series C extension funding. Most of our teams work remotely and have access to our offices in Denver, Colorado, New, York, New York, Dallas, Texas, and Lisbon, Portugal with some roles requiring you to be on-site in a location. Cleerly has created a new standard of care for heart disease through value-based, AI-driven precision diagnostic solutions with the goal of helping prevent heart attacks. Our technology goes beyond traditional measures of heart disease by enabling comprehensive quantification and characterization of atherosclerosis, or plaque buildup, in each of the heart arteries. Cleerly’s solutions are supported by more than a decade of performing some of the world’s largest clinical trials to identify important findings beyond symptoms that increase a person’s risk of heart attacks. At Cleerly, we collaborate digitally and use a wide variety of systems. Our people use Google Workspace (GMail, Drive, Docs, Sheets, Slides), Slack, Confluence/Jira, and Zoom Video, prior experience in these areas is a plus. Role or department specific technology needs may vary and will be listed as requirements in the job description. While we are mostly a remote company, travel is required for some team meetings and cross function projects typically once per month or once per quarter, for some roles like sales or external facing roles travel could be up to 90% of the time. Cleerly is committed to providing safe and effective medical software that meets customer needs and our intended use. The adherence to all applicable regulatory and statutory requirements establishes a clear framework for setting measurable quality objectives. Our commitment to continually improving our products and processes proactively manages risks, ensuring ongoing compliance throughout the entire software lifecycle.  Understanding this role's relevance and importance is critical to achieving Cleerly's quality objectives. ## About the Opportunity We are seeking a Senior Software Engineer to design, build, deploy, monitor, and optimize production-ready ML services in regulated healthcare. You will work hands-on to package, test, orchestrate, deploy, and maintain ML models, improve workflows, and implement CI/CD and automated testing to ensure reliability, performance, and faster delivery of business value. ## Responsibilities - Design, build, and deploy scalable AI/ML services with clear service boundaries, making pragmatic trade-offs across performance, maintainability, security, and long-term extensibility. - Own full lifecycle delivery of complex features from architectural planning and API design to implementation and post-release observability. - Define and enforce robust verification and validation for AI services including unit, integration, and end-to-end testing to ensure reliability of code in production and compliance with our Quality Management System and regulatory standards. - Integrate CI/CD and MLOps practices for automated model builds, testing, and deployment. - Translate product requirements into well-defined technical designs proactively shaping implementation details. - Contribute to the necessary technical documentation required for regulatory submissions. - Collaborate cross functionally to reduce knowledge silos and ensure continuity in critical systems through cross-training and documentation. ## Requirements - Bachelor’s or Master’s degree in Computer Science, Software Engineering, or related field - 7+ years of software engineering experience, with expertise in AI production systems (Python, PyTorch) and data services (SQL, Postgres, NoSQL, Redis or similar). - Experience with unit, integration testing for ML models, including data validation, correctness checks, and reproducibility. - Experience with CI/CD, Orchestration tools (Airflow, MLflow, Kubernetes, Terraform) and ML/data platforms(SageMaker, Databricks, Unity Catalog, Snowflake/Snowpark) to build scalable ML data pipelines and model workflows. - Strong collaboration skills to work effectively with ML scientists, engineers, and regulatory teams. - Comfortable operating in ambiguity and driving clarity across product, engineering, and business stakeholders. This role is eligible for a 15% target annual bonus, resulting in the following base salary and Total Target Compensation (TTC) ranges: - Base Salary: $153,000 - $179,000 - TTC: $176,000 - $206,000 *Total Target Compensation (TTC): Total Cash Compensation (including base pay, variable pay, commission, bonuses, etc.) Additionally, stock options, paid benefits, and employee perks are part of your total rewards. Working at Cleerly takes HEART. Discover our Core Values: - H: Humility- be a servant leader - E: Excellence- deliver world-changing results - A: Accountability- do what you say; expect the same from others - R: Remarkable- inspire & innovate with impact - T: Teamwork- together we win Don’t meet 100 percent of the qualifications? Apply anyway and help us diversify our candidate pool and workforce. We value experience, whether gained formally or informally on the job or through other experiences. Job duties, activities and responsibilities are subject to change by our company. OUR COMPANY IS AN EQUAL OPPORTUNITY EMPLOYER.  We do not discriminate on the basis of race, color, national origin, ancestry, citizenship status, protected veteran status, religion, physical or mental disability, marital status, sex, sexual orientation, gender identity or expression, age, or any other basis protected by law, ordinance, or regulation. For more information see our Privacy Policy (https://cleerlyhealth.com/privacy-policy). All official emails will come from @cleerlyhealth.com email accounts. #Cleerly ## About Cleerly ## Company Overview - **One-liner**: Cleerly is an AI-driven platform that quantifies and assesses coronary artery disease from noninvasive CT imaging to deliver clinically actionable insights for personalized heart attack prevention. - **Entity Type**: Private (Series C‑II – latest round raised $106M) - **Headquarters**: Denver, Colorado, USA - **Founded**: 2017 - **Founders**: James K. Min, MD (Founder & CEO) ## Core Business - **Primary industry**: Healthcare technology – cardiovascular diagnostics, medical imaging, artificial intelligence - **Target customers**: B2B – hospitals, cardiology clinics, imaging centers, payors, and referring physicians - **Mission**: To establish a new standard of precision heartcare and eliminate heart attacks through comprehensive, AI‑enabled phenotyping of coronary artery disease. ## Products & Services - **Cleerly Platform** (Web‑based SaaS): AI‑powered software that analyzes coronary CCTA images to quantify plaque volume, composition, stenosis severity, and detect likely ischemia. FDA‑cleared for clinical use. Includes **Cleerly ISCHEMIA**, a module validated in the CREDENCE and PACIFIC trials against invasive FFR. - **Cleerly Labs** (Research/Development arm): Focused on continuous innovation and patent‑protected algorithms (over 112 patents filed) for plaque analysis and risk determination. ## Market Standing - **Valuation/Market Cap**: Not publicly disclosed - **Key Metric**: Total funding raised – $388.55M across multiple rounds (latest Series C‑II closed ~2024, $106M) - **Notable Investors/Partners**: Battery Ventures, Insight Partners, New Leaf Venture Partners, LRVHealth, The Cigna Group Ventures, and 17+ additional institutional investors - **Growth Signals**: Published peer‑reviewed evidence from large multicenter trials (CREDENCE, PACIFIC‑1); FDA clearance for ischemia detection; remote‑first team spanning the U.S. and Portugal; headcount growth implied by active hiring across engineering, clinical, and commercial roles. ## Competitive Advantages - **Clinical‑grade AI**: FDA‑cleared machine‑learning algorithms validated against invasive gold standards (IVUS, NIRS, FFR) in thousands of patients. - **Comprehensive evidence base**: Proven diagnostic accuracy superior to FFRCT and stress testing in the CREDENCE trial; only non‑invasive ischemia test prognostic for future MACE events in the PACIFIC trial. - **Deep patent portfolio**: 112+ patents covering systems and methods for non‑invasive plaque analysis and risk determination. - **Full‑stack workflow**: From image ingestion to structured reports, reducing unnecessary follow‑up testing and improving diagnostic confidence. ## Strategic Focus - Expand global adoption of non‑invasive CAD phenotyping as a standard of care. - Continue clinical validation and regulatory expansion (FDA clearance for additional indications). - Scale commercial partnerships with health systems, payors, and imaging providers. - Grow the remote‑first team in engineering, data science, and clinical development. ## Why Work Here - **Remote‑first culture**: HQ in Denver with hubs in New York City and Lisbon; teams collaborate via Slack, Zoom, and Google Suite; regular off‑sites. - **Comprehensive benefits**: Multiple medical/dental/vision plans, 401K with company match, generous parental leave, discretionary PTO, monthly wellness and internet stipends, annual L&D stipend, home office support. - **Equity for all**: Every team member receives equity upon joining. - **Values‑driven**: “HEART” principles – Humility, Excellence, Accountability, Remarkable, Teamwork – celebrated quarterly with awards. - **Meaningful mission**: Direct impact on preventing heart attacks; work is grounded in life‑changing clinical results. ## Sources 1. [cleerlyhealth.com](https://cleerlyhealth.com) 2. [cleerlyhealth.com/about-us](https://cleerlyhealth.com/about-us) 3. [cleerlyhealth.com/careers](https://cleerlyhealth.com/careers) 4. [cleerlyhealth.com/leadership](https://cleerlyhealth.com/leadership) 5. 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