--- title: 'SRA I, Compound Management at Maze Therapeutics' canonical: 'https://feeny.ai/job/sra-i-compound-management-maze-therapeutics-south-san-francisco-qv6xjb3japxy' type: 'job' last_seen: '2026-11-08' --- # SRA I, Compound Management at Maze Therapeutics - **Company:** Maze Therapeutics - **Location:** South San Francisco, CA - **Posted:** 2026-10-27 - **Last confirmed live:** 2026-11-08 - **Apply:** http://www.mazetx.com/careers/?gh_jid=8906972002 ## Job description The Position The Drug Discovery team is looking for a Senior Research Associate I, Compound Management to join our group. In this role, you will help power the discovery of new medicines by ensuring scientists across the organization have access to the high-quality compounds and samples needed to advance research programs. Your work will directly enable scientists to advance programs aimed at translating novel genetic insights into lifesaving medicines. You will partner closely with colleagues across Drug Discovery, including Chemistry, Biology, and other cross-functional teams, to manage compound inventory, support sample management workflows, and help maintain the efficient operation of our compound management capabilities. As a key member of a collaborative and growing organization, you will contribute to the infrastructure and processes that drive our research and drug discovery goals. This role offers a unique opportunity to expand your technical expertise, develop strong cross-functional relationships, and grow your career within a dynamic biotech environment. If you are detail-oriented, analytical, and motivated to make an impact, you will find meaningful opportunities to learn and contribute as the company continues to grow. This position reports to the Director of Chemistry. The Impact You’ll Have - Manage the weighing, storage, maintenance, and distribution of compound inventories. - Responsible for the operation of automated laboratory equipment to support the processing of samples. - Proactively monitor the compound request queue and fulfill the requests in a timely manner. - Partner with Facilities Department for the shipping and tracking of compounds both locally and internationally to our collaborating CROs. - Routinely perform sample QC checks and analysis. - Coordinate with R&D operations, vendors, and CROs to procure, track, and process samples to support internal and external studies. - Assist in the development and implementation of workflows to support error-free high throughput compound processing. - Coordinate cross-departmentally for routine or ad hoc compound plating. - Maintain lab consumable inventory. ## What We’re Looking For - Minimum of a BS degree in Biological or Chemical Sciences with 3+ years of experience in small molecule compound handling and processing. - Experience with laboratory automation, specifically liquid handling platforms like Tecan EVO, Labcyte ECHO or similar. - Experience with troubleshooting and maintenance of instrumentation platforms and automated integrated systems. - Experience with optimizing compound processing workflows including knowledge and use of Mosaic is desired. - Innate attention to detail, organization skills, ability to multi-task and work across initiatives simultaneously under tight deadlines - Effective communication skills and strong interpersonal skills to engage in cross-functional collaboration and teamwork. ## About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. Our Core Values Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission. Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. Stand True – Our integrity is foundational; it guides us no matter the obstacle. The expected annual salary range for employees located in the San Francisco Bay Area is $105,000 - $128,000. Additionally, this position is eligible for an annual performance bonus. Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future. Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy. #LI-Hybrid ## About Maze Therapeutics ## Company Overview - **One-liner**: Maze Therapeutics is a clinical-stage biopharmaceutical company developing small molecule precision medicines for common diseases, primarily kidney disease, by leveraging human genetics and its proprietary Compass platform. - **Entity Type**: Public (NASDAQ: MAZE) - **Headquarters**: South San Francisco, California, United States - **Founded**: 2018 - **Founders**: Not publicly listed as individual founders; the company was established by a team of geneticists and industry veterans. ## Core Business - **Primary industry/industries**: Biotechnology / Biopharmaceuticals (Precision Medicine) - **Target customers**: B2B (partners and investors), B2C (patients with APOL1-mediated kidney disease, chronic kidney disease, and phenylketonuria) - **Mission or purpose statement**: "Harnessing the power of genetics to transform the lives of patients" by translating genetic insights into effective precision medicines. ## Products & Services - **MZE829 (Lead Program)**: An oral, small molecule, dual-mechanism APOL1 inhibitor for the treatment of APOL1-mediated kidney disease (AMKD). Recently reported positive topline Phase 2 HORIZON trial data. - **MZE782 (SLC6A19 Inhibitor)**: A precision medicine in development for chronic kidney disease (CKD) and phenylketonuria (PKU), currently in clinical trials. - **Maze Compass™ Platform**: A proprietary platform that leverages variant functionalization to link genetic variants to disease pathways, enabling the discovery and design of precision medicines. - **Other Pipeline Programs**: Several additional programs in drug discovery targeting renal, cardiovascular, and metabolic diseases. ## Market Standing - **Valuation/Market Cap**: Approximately **$1.48 Billion** (as of mid-2026, per CB Insights market cap data). - **Key Metric**: **Total Raised** (including IPO): **$496 Million**. The company also announced a **$150 Million registered offering** in 2026. - **Notable Investors/Partners**: Key investors include **Third Rock Ventures**, **Gilead Sciences**, **Genentech**, **Denali Therapeutics**, and **Calico Life Sciences** (as top talent sources and likely institutional backers). The company went public via a PIPE/IPO structure. - **Growth Signals**: - Positive topline data from the Phase 2 HORIZON trial of MZE829 (announced March 2026). - Three clinical-stage programs and several discovery-stage programs. - Active job postings increased by **120% year-over-year**. - Headcount of approximately 150 employees (based on LinkedIn data showing ~150 total employees). ## Competitive Advantages - **Proprietary Compass Platform**: A unique, data-driven platform that functionally validates genetic variants, giving Maze a differentiated ability to identify and target disease-causing pathways that are often overlooked. - **Focus on Common Diseases**: Unlike many precision medicine companies that focus on rare diseases, Maze targets large, unmet medical needs (e.g., chronic kidney disease), which represents a massive market opportunity. - **Strong Genetic Foundation**: The company’s entire strategy is built on robust human genetic evidence, reducing the risk of late-stage clinical failures and increasing the probability of success. - **Experienced Leadership Team**: The team includes veterans from leading biotech and pharma companies (Gilead, Genentech, Amgen), providing deep industry expertise in drug development and commercialization. ## Strategic Focus - **Advance Lead Programs**: Primary focus is on progressing MZE829 through Phase 2/3 trials for APOL1-mediated kidney disease and advancing MZE782 for CKD and PKU. - **Expand Pipeline**: Leveraging the Compass platform to identify and develop additional precision medicines for renal, cardiovascular, and metabolic diseases. - **Clinical Data Generation**: Delivering key clinical readouts to support regulatory filings and potential partnerships. - **Commercial Preparation**: Building the infrastructure and team (e.g., Senior Director, Talent Acquisition; Senior Director, Pharmaceutical Development) to prepare for potential late-stage success and launch. ## Why Work Here - **Mission-Driven Culture**: The company is deeply committed to "harnessing the power of genetics to transform the lives of patients," with core values of "Impact Obsessed," "Stand True" (integrity), and "Further Together" (teamwork and resilience). - **Supportive Work Environment**: Maze promotes a culture that encourages "vision, initiative, and the development of talent," with a "stimulating atmosphere where people enjoy coming to work." - **Comprehensive Benefits**: Offers "comprehensive and competitive health, financial, paid time off and many other benefits designed to promote the health and financial well-being of employees and their families." - **Equal Opportunity Employer**: Committed to diversity and non-discrimination. - **Growth Trajectory**: As a public clinical-stage company with positive clinical data and a 120% increase in job postings year-over-year, there are significant opportunities for career growth and impact. - **Location**: Based in South San Francisco (a major biotech hub), though specific remote/hybrid policy is not publicly detailed. ## Sources 1. [mazetx.com](https://mazetx.com/) 2. [mazetx.com](https://mazetx.com/about-us/) 3. [mazetx.com](https://mazetx.com/careers/) 4. [cbinsights.com](https://www.cbinsights.com/company/maze-therapeutics) 5. [linkedin.com](https://www.linkedin.com/company/mazetx) ## Other roles at Maze Therapeutics - [Director, GMP Quality Assurance](https://feeny.ai/job/director-gmp-quality-assurance-maze-therapeutics-south-san-francisco-ehw65s1rkfyr) — South San Francisco, CA - [Senior Director, Patient Advocacy](https://feeny.ai/job/senior-director-patient-advocacy-maze-therapeutics-united-states-grcygefjehsp) — United States - [Associate Director, CMC Project Management](https://feeny.ai/job/associate-director-cmc-project-management-maze-therapeutics-south-san-francisco-7wqp0jppgr7v) — South San Francisco, CA - [Director, Field Medical - West](https://feeny.ai/job/director-field-medical-west-maze-therapeutics-united-states-1mkq4fhpegeg) — United States - [Director, Field Medical - East](https://feeny.ai/job/director-field-medical-east-maze-therapeutics-united-states-6gdfvzad7y1y) — United States - [Director, Field Medical - Central](https://feeny.ai/job/director-field-medical-central-maze-therapeutics-united-states-z7tsmyrg7bgf) — United States - [Senior Director, Information Technology](https://feeny.ai/job/senior-director-information-technology-maze-therapeutics-south-san-francisco-gzknm40mvm03) — South San Francisco, CA - [Manager, Chemical Development](https://feeny.ai/job/manager-chemical-development-maze-therapeutics-south-san-francisco-8x7qw5qcxd7k) — South San Francisco, CA - [Senior Project Manager, Clinical Operations](https://feeny.ai/job/senior-project-manager-clinical-operations-maze-therapeutics-south-san-francisco-tdcv9cmr2ey2) — South San Francisco, CA - [Director, Clinical Business Operations](https://feeny.ai/job/director-clinical-business-operations-maze-therapeutics-south-san-francisco-asppwh94sg0p) — South San Francisco, CA