--- title: 'Strategic Finance Lead at Pattern Biosciences' canonical: 'https://feeny.ai/job/strategic-finance-lead-pattern-biosciences-south-san-francisco-n9x7mg1a101x' type: 'job' last_seen: '2026-11-08' --- # Strategic Finance Lead at Pattern Biosciences - **Company:** Pattern Biosciences - **Location:** South San Francisco, CA - **Employment:** full-time - **Work type:** onsite - **Posted:** 2026-01-08 - **Last confirmed live:** 2026-11-08 - **Apply:** https://jobs.lever.co/pantheon-bio/879d55ac-0cd1-4f36-bfb4-a0440e9063ee ## Job description We’re seeking an experienced and highly analytical Strategic Finance leader to play a key operational role within our growing team. This role sits at the intersection of financial planning and operational execution serving as the connective tissue between our scientific, operational, and corporate functions. You’ll own FP&A and manage critical work streams that interface with accounting, operations, legal, and HR. This is a rare opportunity to help shape the foundation of a fast-growing biotech, translating plans into financial insight, building scalable processes, and ensuring the company operates with clarity, discipline, and foresight. Primary Responsibilities - Lead annual and quarterly budgeting cycles; drive development, consolidation, and alignment across teams. - Report on Budget vs. Actuals, perform variance analyses, and provide insights for leadership. - Build and maintain long-range forecasts and cash runway models for strategic planning. - Partner cross-functionally with R&D and functional leaders to translate scientific goals into financial projections. - Prepare finance materials for Board meetings and investor updates. - Serve as the primary contact for external partners, overseeing equity administration (Carta), payroll and HR systems (Rippling), corporate credit cards and invoices (Ramp) and 401(k)/benefits. - Ensure accuracy, compliance, and scalability across all finance and HR processes. - Oversee 409A valuations and financial models supporting fundraising and strategic planning. - Manage cap table accuracy, option pool planning, and coordination with legal counsel. - Liaise with corporate counsel to ensure smooth legal operations and governance documentation. - Partner with IP counsel to manage filings, budgets, and deadlines. - Partner with HR on offer letters, compensation benchmarking, and committee preparations. - Align HR systems, Carta equity data, and finance documentation for total rewards accuracy. - Review and approve invoices and T&E submissions for accuracy and policy compliance. - Manage corporate credit cards, bill pay and invoices (Ramp) - Oversee purchasing workflows (lab consumables, vendors, etc.) to ensure spend control and transparency. Required Skills & Qualifications - 7–10+ years of experience in FP&A, strategic finance, or business operations; biotech or life sciences background preferred. - Proven success leading budgeting, forecasting, and financial modeling processes. - Ability to balance strategic planning with hands-on execution. - Experience partnering across R&D, Legal, HR, and external finance teams. - Strong analytical skills, judgment, and discretion with sensitive information. - Ability to thrive in an early-stage, fast-paced, and evolving environment. At Pantheon Bio, we design biological circuits at the intersection of synthetic biology and AI for cell-specific targeting of cancer tissue. By integrating data-driven design into every step—from DNA constructs to AAV-based delivery systems—we are building precise, rationally engineered, curative therapies. Our mission driven team in South San Francisco is dedicated to pioneering new technologies and saving lives. ## About Pattern Biosciences ## Company Overview - **One-liner**: Pattern Biosciences builds DNA computers that run molecular programs inside human cells to treat cancer and other diseases with unprecedented precision. - **Entity Type**: Private (Privately Held; Pre-Seed Stage) - **Headquarters**: South San Francisco, California, United States (with additional presence in Switzerland) - **Founded**: 2018 (based on earliest grant funding records) - **Founders**: Yaakov (Kobi) Benenson (CEO) and Bartolomeo Angelici (VP Discovery Research) ## Core Business - **Primary Industry**: Biotechnology Research (Synthetic Biology / DNA Computing for Therapeutics) - **Target Customers**: B2B/B2C – developing therapies aimed at oncology and other hard-to-treat diseases; potential partners include pharmaceutical and biotech companies. - **Mission Statement**: “Reprogram disease for health” (from careers page) / “We build DNA computers to cure disease.” ## Products & Services - **DNA Computer Platform (Therapeutic Candidates)**: A proprietary biomolecular computing technology that uses transcription factors, microRNAs, promoters, and enhancers as inputs. The platform senses multiple molecular cues at the single‑cell level, computes a molecular program, and activates a potent therapeutic effector when a disease‑specific pattern is identified. This enables therapies that can target previously undruggable drivers of disease. ## Market Standing - **Valuation / Market Cap**: Not publicly available - **Key Metric**: Total known funding – Pre‑Seed round (September 2023, 1 investor) plus early grants: ~USD 81,868 (2019) and EUR 50,000 (2018). Additional pre‑seed amount not disclosed. - **Notable Investors**: Not named in public sources. - **Growth Signals**: - Headcount of 18 employees (+26.7% YoY growth). - Active job postings for In Vivo Scientist, Biomarker Scientist, and Finance & Business Operations Lead. - Growing LinkedIn presence (+21.5% yearly follower growth to 4,356). - Described as building a “world‑class team” to translate two decades of DNA computing research into the clinic. ## Competitive Advantages - **Proprietary DNA Computing Platform**: The only company systematically engineering multi‑input molecular computation at the single‑cell level using bottom‑up, data‑driven design. - **Targets Undruggable Drivers**: Leverages intracellular molecules (e.g., transcription factors, microRNAs) that are key disease drivers but largely inaccessible to conventional small molecules or biologics. - **Rational Engineering Approach**: Uses a build‑design‑test cycle with sophisticated *in vitro* and *in vivo* models, enabling faster iteration and higher probability of success than traditional drug discovery. ## Strategic Focus - **Current Priorities**: Advancing early‑stage pipeline of cancer therapies; validating and iterating therapeutic candidates in clinically‑relevant models; expanding the R&D team (especially in vivo pharmacology, biomarker science, and data engineering). - **Direction for Growth**: Transition from platform development toward IND‑enabling studies and eventual clinical trials, with an emphasis on curative therapies for diseases where the one‑drug‑one‑target paradigm has failed. ## Why Work Here - **Culture**: Small, tight‑knit team (18 people) with a shared mission to “cure disease” using cutting‑edge synthetic biology. Emphasis on rational, data‑driven engineering and collaborative science. - **Work Model**: Fully in‑person at the South San Francisco headquarters. No remote or hybrid options mentioned. - **Notable Perks / Engineering Culture**: Opportunity to work at the forefront of DNA computing and synthetic biology; direct impact on therapeutic design from bench to clinic; access to state‑of‑the‑art lab facilities and sophisticated model systems. The company values iterative debugging – failure modes are quickly identified and corrected. - **Open Roles (as of mid‑2025)**: In Vivo Scientist, Oncology; Biomarker Scientist, Immuno‑oncology; Finance & Business Operations Lead. ## Sources 1. [patternbio.com](https://www.patternbio.com/) – Company overview and technology description 2. [patternbio.com/careers](https://patternbio.com/careers) – Careers page with headquarters, mission, and team philosophy 3. [patternbio.com/home-copy](https://www.patternbio.com/home-copy) – Founders list and detailed platform explanation 4. [linkedin.com/company/pattern-biosciences](https://linkedin.com/company/pattern-biosciences) – Employee count, growth, funding history, job postings, and company details ## Other roles at Pattern Biosciences - [In vivo Scientist, Oncology](https://feeny.ai/job/in-vivo-scientist-oncology-pattern-biosciences-south-san-francisco-aafan0a641cs) — South San Francisco, CA - [Corporate Counsel](https://feeny.ai/job/corporate-counsel-pattern-biosciences-south-san-francisco-cykshnnbanyh) — South San Francisco, CA - [In vivo Research Associate, Oncology](https://feeny.ai/job/in-vivo-research-associate-oncology-pattern-biosciences-south-san-francisco-vt7a9t7s29tp) — South San Francisco, CA - [Strategic Finance Lead](https://feeny.ai/job/strategic-finance-lead-spark-advisors-new-york-7ycdatfjjjnv) — New York, NY - [Strategic Finance Lead](https://feeny.ai/job/strategic-finance-lead-traba-new-york-tb3036y9krcw) — New York, NY - [Strategic Finance Lead](https://feeny.ai/job/strategic-finance-lead-lambda-san-francisco-q1x9bgf21vnc) — San Francisco, CA - [Strategic Finance Lead](https://feeny.ai/job/strategic-finance-lead-numeral-new-york-3v8t01eqjxjv) — New York, NY - [Strategic Finance Lead](https://feeny.ai/job/strategic-finance-lead-inferact-san-francisco-8w870avftckq) — San Francisco, CA - [Strategic Finance Lead](https://feeny.ai/job/strategic-finance-lead-picogrid-el-segundo-80n3es14a9jv) — El Segundo, CA - [Strategic Finance Lead](https://feeny.ai/job/strategic-finance-lead-iru-miami-06rwavscd09w) — Miami, FL