--- title: 'Thought Leader Liaison - Southeast at Dyne Therapeutics' canonical: 'https://feeny.ai/job/thought-leader-liaison-southeast-dyne-therapeutics-drpxdj77z6cn' type: 'job' last_seen: '2026-09-14' --- # Thought Leader Liaison - Southeast at Dyne Therapeutics - **Company:** Dyne Therapeutics - **Compensation:** $230k–$260k - **Work type:** onsite - **Posted:** 2026-07-20 - **Last confirmed live:** 2026-09-14 - **Apply:** https://job-boards.greenhouse.io/dynetherapeutics/jobs/6114395004 ## Job description Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. 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Role Summary: The Director, Thought Leader Liaison develops and executes a strategic engagement model with external thought leaders in rare neuromuscular diseases to support Dyne’s commercial objectives. This role builds credible, compliant, and value-driven relationships with neuromuscular experts and advocates, translating insights into actionable commercial strategy. The role serves as a senior external-facing representative of Dyne, shaping disease-state understanding, treatment adoption, and long-term success of Dyne’s neuromuscular portfolio, and will be responsible for defined activities within the Southeast TLL region. This is a field-based position.  Candidates must reside within the assigned territory and within reasonable driving distance of a major commercial airport capable of supporting frequent regional and national travel. Primary Responsibilities include: Thought Leader Strategy & Engagement - Develops and executes a comprehensive thought leader engagement strategy focused on rare neuromuscular diseases, aligned with Dyne’s commercial and portfolio priorities. - Identifies, profiles, and prioritizes national and regional neuromuscular thought leaders based on expertise, influence, and strategic relevance. - Builds and sustains long-term, trust-based relationships with clinicians and experts treating rare neuromuscular disorders through compliant, value-driven engagement. - Serves as a credible commercial partner in discussions related to disease state education, evolving treatment paradigms, and unmet needs in neuromuscular disease. Insight Generation & Strategic Activation - Captures, synthesizes, and translates insights from neuromuscular thought leaders into actionable recommendations for brand, launch, and lifecycle strategy. - Provides strategic input into positioning, messaging, and tactical planning that reflects the unique dynamics of rare disease diagnosis, treatment, and patient journeys. - Monitors KOL insights related to current and future market dynamics and competitive intelligence through customer meetings, congresses, advisory boards, and analytics. - Shares insights with commercial leadership and cross-functional partners to inform decision-making and optimize execution. Congress, Advisory Board & Peer-to-Peer Engagement - Leads commercial engagement strategy for key neuromuscular congresses, including pre-, during-, and post-meeting planning and follow-up. - Designs and executes advisory boards, speaker programs, and peer-to-peer educational initiatives focused on rare neuromuscular disease education. - Identifies and recruits appropriate KOLs for content development and other marketing projects, such as web content, training, handouts, and related materials. - Partners cross-functionally to ensure consistency, effectiveness, and compliance across engagement forums. Cross-Functional Leadership & Governance - Collaborates and interfaces regularly across regions and with multiple departments, including Sales, Marketing, Medical Affairs, Market Access, Training, Legal, and Compliance, to ensure aligned and compliant execution. - Manages vendor partnerships as needed, including medical education agencies, meeting services providers, and other external partners. - Establishes metrics to assess effectiveness, impact, and ROI of thought leader engagement activities. - Ensures all interactions adhere to regulatory, legal, and company compliance standards. Education and Skills Requirements: - Bachelor’s degree required; advanced degree preferred. - 10+ years of experience in biotechnology or pharmaceutical commercial roles, with experience in rare disease or specialty markets strongly preferred. - Demonstrated experience engaging neuromuscular or rare disease thought leaders in a commercial context. - Strong understanding of the rare disease commercialization landscape, including diagnosis complexity, referral dynamics, and patient advocacy. - Proven ability to translate complex scientific and clinical insights into clear, innovative, and actionable commercial strategies. Self-starter with the ability to deliver results in therapeutic areas with high unmet need. - Excellent interpersonal, oral, and written communication skills, with strong execution focus and executive presence, and the ability to influence without authority. - Strong cross-functional collaboration skills and experience operating in matrixed organizations. - Demonstrated commitment to ethical, compliant engagement practices. - Proven ability to manage a large geographical territory. - Domestic travel up to 80% is required. #LI-Remote MA Pay Range $230,000—$260,000 USD The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload. Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. ## About Dyne Therapeutics ## Company Overview - **One-liner**: Dyne Therapeutics is a clinical-stage biotechnology company developing targeted nucleic acid therapies for genetically driven neuromuscular diseases using its proprietary FORCE™ platform. - **Entity Type**: Public (NASDAQ: DYN) - **Headquarters**: Waltham, Massachusetts, United States - **Founded**: 2018 - **Founders**: Not publicly available (the company was co-founded by a team of scientists and entrepreneurs; individual names not surfaced in search results) ## Core Business - **Primary industry**: Biotechnology / Biopharmaceuticals – rare neuromuscular disease therapeutics - **Target customers**: B2B / B2G – regulatory agencies, healthcare providers, payers, and most importantly patients with Duchenne muscular dystrophy (DMD), myotonic dystrophy type 1 (DM1), facioscapulohumeral muscular dystrophy (FSHD), and Pompe disease. - **Mission / Purpose**: “Delivering functional improvement for people living with neuromuscular diseases.” [dyne-tx.com](https://www.dyne-tx.com/) ## Products & Services Dyne’s pipeline is built around its FORCE™ platform, which uses an antigen-binding fragment (Fab) conjugated to transferrin receptor 1 (TfR1) to deliver therapeutic payloads to muscle and the central nervous system. - **Z‑rostudirsen (DYNE‑251)** – An investigational therapeutic for DMD patients amenable to exon 51 skipping. Consists of a phosphorodiamidate morpholino oligomer (PMO) conjugated to an anti‑TfR1 Fab. Phase 1/2 DELIVER trial met primary endpoint; BLA submission for U.S. Accelerated Approval planned for Q2 2026 with potential launch in Q1 2027. [investors.dyne-tx.com](https://investors.dyne-tx.com/news-releases/news-release-details/dyne-therapeutics-reports-fourth-quarter-and-full-year-2025) - **Z‑basivarsen (DYNE‑101)** – Investigational therapeutic for DM1, using an antisense oligonucleotide (ASO) conjugated to anti‑TfR1 Fab. Phase 1/2 ACHIEVE trial fully enrolled; Phase 3 HARMONIA trial ongoing. [dyne-tx.com](https://www.dyne-tx.com/pipeline/) - **DYNE‑302** – Preclinical candidate for FSHD, using an siRNA payload to suppress DUX4 expression. [dyne-tx.com](https://www.dyne-tx.com/pipeline/) - **DMD Franchise Expansion** – Four additional development candidates (DYNE‑253, DYNE‑245, DYNE‑244, DYNE‑255) targeting exons 53, 45, 44, and 55 for DMD, entering IND‑enabling studies. [investors.dyne-tx.com](https://investors.dyne-tx.com/news-releases/news-release-details/dyne-therapeutics-reports-fourth-quarter-and-full-year-2025) ## Market Standing - **Valuation / Market Cap**: Not disclosed in search results (public company; market cap fluctuates with stock price; current figure not provided in the sources). - **Key Metric**: Cash, cash equivalents and marketable securities of **$1.1 billion** as of December 31, 2025, providing runway into Q1 2028. [investors.dyne-tx.com](https://investors.dyne-tx.com/news-releases/news-release-details/dyne-therapeutics-reports-fourth-quarter-and-full-year-2025) - **Notable Investors / Partners**: Not listed in provided search results (likely institutional investors; prior venture rounds not detailed here). - **Growth Signals**: - Headcount grew **38.2% YoY** to **227 employees** (2025). [linkedin.com](https://www.linkedin.com/company/dynetx) - Positive topline results from DELIVER trial for z‑rostudirsen; potential first product launch in Q1 2027 if approved. - Advancing five distinct clinical/preclinical programs across multiple neuromuscular indications. ## Competitive Advantages - **FORCE™ Platform**: Differentiated delivery technology that uses a TfR1‑binding Fab to enable broad and deep tissue penetration in both muscle and CNS – addressing one of the biggest hurdles in neuromuscular drug development. - **Best‑in‑Class Potential**: Clinical data for z‑rostudirsen showed statistically significant dystrophin expression (5.46% of normal at 6 months, 7‑fold change) and preservation of lung function (FVC%p) compared to placebo, despite a small trial not powered for functional endpoints. - **Broad Pipeline**: Covering multiple exon‑skipping opportunities in DMD as well as entirely different diseases (DM1, FSHD, Pompe) with the same core platform, reducing risk and enabling rapid expansion. ## Strategic Focus - **Regulatory Submission**: File a Biologics License Application (BLA) for z‑rostudirsen in Q2 2026 under U.S. Accelerated Approval pathway. - **Late‑Stage Trials**: Initiate two field‑defining Phase 3 confirmatory trials (FORZETTO for DMD and HARMONIA for DM1) in 2026 following FDA alignment on design. - **Pipeline Expansion**: Move four additional DMD exon‑skipping candidates into IND‑enabling studies and advance preclinical DYNE‑302 (FSHD) toward the clinic. - **Commercial Readiness**: Prepare for potential first‑ever company launch in Q1 2027 with a focus on U.S. market, while also pursuing ex‑U.S. approval pathways. ## Why Work Here - **Mission‑Driven Culture**: The company’s “One Dyne community” ethos emphasizes accountability, transparency, fearlessness, and a relentless drive to deliver functional improvement for patients and families. [dyne-tx.com](https://www.dyne-tx.com/careers-culture/) - **Competitive Benefits**: Medical, dental, vision, 401(k), flexible vacation, paid holidays including a year‑end office closure, short‑ & long‑term disability, HSA/FSA accounts. [dyne-tx.com](https://www.dyne-tx.com/careers-culture/) - **Work Environment**: Office location in Waltham, MA (Boston area). Remote/hybrid policy not specified in search results; likely on‑site or hybrid for lab‑based roles. Career page lists roles such as Associate Director, Oligonucleotide Development; Scientist, RNA; Director of Training – reflecting a mix of research, clinical, and corporate functions. [job-boards.greenhouse.io](https://job-boards.greenhouse.io/dynetherapeutics) - **Growth Opportunity**: Joining a late‑stage biotech with a validated platform, strong cash position, and a clear path to commercialization – offering employees exposure to both R&D and upcoming launch activities. - **Recruitment Scam Warning**: Dyne posts an explicit notice on its careers page that it never requests financial details or payment during hiring; all legitimate emails come from @dyne‑tx.com addresses. ## Sources 1. [dyne-tx.com – Company Overview](https://www.dyne-tx.com/) 2. [dyne-tx.com – Careers & Culture](https://www.dyne-tx.com/careers-culture/) 3. [dyne-tx.com – Pipeline](https://www.dyne-tx.com/pipeline/) 4. [investors.dyne-tx.com – Q4/Full Year 2025 Results](https://investors.dyne-tx.com/news-releases/news-release-details/dyne-therapeutics-reports-fourth-quarter-and-full-year-2025) 5. [linkedin.com – Dyne Therapeutics Company Profile](https://www.linkedin.com/company/dynetx) 6. [job-boards.greenhouse.io – Dyne Careers Page](https://job-boards.greenhouse.io/dynetherapeutics) ## Other roles at Dyne Therapeutics - [Associate Director, HCP Marketing - DMD](https://feeny.ai/job/associate-director-hcp-marketing-dmd-dyne-therapeutics-remote-r1dnck9gh1bz) - [Associate Director, Clinical Operations Study Lead](https://feeny.ai/job/associate-director-clinical-operations-study-lead-dyne-therapeutics-waltham-evbyf6dxekgd) — Waltham, MA - [Executive Director, TechOps Alliance and Strategic Partnerships](https://feeny.ai/job/executive-director-techops-alliance-and-strategic-partnerships-dyne-wxv9qjfras07) — Waltham, MA - [Senior Director, Quality Control](https://feeny.ai/job/senior-director-quality-control-dyne-therapeutics-waltham-0c14xebc380b) — Waltham, MA - [Senior Director, Medical Affairs Learning & Development](https://feeny.ai/job/senior-director-medical-affairs-learning-development-dyne-therapeutics-waltham-mvej99ejr8y0) — Waltham, MA - [Director, Clinical Scientist](https://feeny.ai/job/director-clinical-scientist-dyne-therapeutics-waltham-jw10cdn5v3ms) — Waltham, MA - [Scientist, Bioconjugation](https://feeny.ai/job/scientist-bioconjugation-dyne-therapeutics-waltham-jg9q1pw4whag) — Waltham, MA - [Principal Scientist, Oligonucleotide (PMO, ASO) Development](https://feeny.ai/job/principal-scientist-oligonucleotide-pmo-aso-development-dyne-therapeutics-2x39whh9swds) — Waltham, MA - [Director, Drug Safety & Pharmacovigilance Scientist](https://feeny.ai/job/director-drug-safety-pharmacovigilance-scientist-dyne-therapeutics-waltham-6e6cxz3bs5mx) — Waltham, MA - [Director, People Operations](https://feeny.ai/job/director-people-operations-dyne-therapeutics-waltham-x79gkrh2bafa) — Waltham, MA